EG21755A - Process for preparing of lercanidipine hydrochloride and their use for the treatment of angina and coronary disease - Google Patents

Process for preparing of lercanidipine hydrochloride and their use for the treatment of angina and coronary disease

Info

Publication number
EG21755A
EG21755A EG40296A EG40296A EG21755A EG 21755 A EG21755 A EG 21755A EG 40296 A EG40296 A EG 40296A EG 40296 A EG40296 A EG 40296A EG 21755 A EG21755 A EG 21755A
Authority
EG
Egypt
Prior art keywords
angina
preparing
treatment
coronary disease
lercanidipine hydrochloride
Prior art date
Application number
EG40296A
Other languages
English (en)
Inventor
Amedeo Leonardi
Original Assignee
Recordati Chem Pharm
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Recordati Chem Pharm filed Critical Recordati Chem Pharm
Application granted granted Critical
Publication of EG21755A publication Critical patent/EG21755A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/80—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D211/84—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen directly attached to ring carbon atoms
    • C07D211/90—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Hydrogenated Pyridines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Plural Heterocyclic Compounds (AREA)
EG40296A 1995-05-12 1996-05-09 Process for preparing of lercanidipine hydrochloride and their use for the treatment of angina and coronary disease EG21755A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ITMI950957A IT1274480B (it) 1995-05-12 1995-05-12 Procedimento migliorato per la preparazione della lercanidipina cloridrato

Publications (1)

Publication Number Publication Date
EG21755A true EG21755A (en) 2002-02-27

Family

ID=11371581

Family Applications (1)

Application Number Title Priority Date Filing Date
EG40296A EG21755A (en) 1995-05-12 1996-05-09 Process for preparing of lercanidipine hydrochloride and their use for the treatment of angina and coronary disease

Country Status (37)

Country Link
EP (1) EP0824517B1 (fr)
JP (1) JP4038622B2 (fr)
KR (1) KR100395441B1 (fr)
CN (1) CN1101810C (fr)
AR (1) AR002739A1 (fr)
AT (1) ATE221050T1 (fr)
AU (1) AU694046B2 (fr)
BG (1) BG62400B1 (fr)
BR (1) BR9608374A (fr)
CA (1) CA2217849C (fr)
CZ (1) CZ288634B6 (fr)
DE (1) DE69622552T2 (fr)
DK (1) DK0824517T3 (fr)
DZ (1) DZ2032A1 (fr)
EA (1) EA000346B1 (fr)
EE (1) EE03351B1 (fr)
EG (1) EG21755A (fr)
ES (1) ES2179942T3 (fr)
HU (1) HU226709B1 (fr)
IL (1) IL118143A (fr)
IN (1) IN188486B (fr)
IT (1) IT1274480B (fr)
MA (1) MA23858A1 (fr)
MX (1) MX9708662A (fr)
MY (1) MY113802A (fr)
NO (1) NO309423B1 (fr)
NZ (1) NZ309059A (fr)
PL (1) PL185260B1 (fr)
PT (1) PT824517E (fr)
RO (1) RO119616B1 (fr)
SA (1) SA96170216B1 (fr)
SK (1) SK283321B6 (fr)
TN (1) TNSN96069A1 (fr)
TW (1) TW404940B (fr)
UA (1) UA46769C2 (fr)
WO (1) WO1996035668A1 (fr)
ZA (1) ZA963716B (fr)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6852737B2 (en) 2001-08-06 2005-02-08 Recordati Ireland Limited Crude and crystalline forms of lercanidipine hydrochloride
ITMI20011726A1 (it) * 2001-08-06 2003-02-06 Recordati Ind Chimica E Farma Forme polimorfe della lercanidipina cloridrato
WO2004035051A1 (fr) * 2002-10-16 2004-04-29 Recordati Ireland Limited Polytherapie a base de lisinopril/lercanidipine
AR052918A1 (es) 2005-02-25 2007-04-11 Recordati Ireland Ltd Clorhidrato de lercanidipina amorfo
KR100713136B1 (ko) * 2005-05-04 2007-05-02 주식회사 대희화학 무수 레르카니디핀 염화수소 결정다형의 개선된 신규결정화 방법
PT1891009E (pt) * 2005-06-15 2010-01-19 Hetero Drugs Ltd Processo inédito para a preparação de lercanidipina
KR20080048065A (ko) 2005-09-16 2008-05-30 그렌마크 파머수티칼스 엘티디. 다형 형태의 염산 레르카니디핀 및 이것의 제조방법
KR100811497B1 (ko) * 2005-10-19 2008-03-07 신풍제약주식회사 무수 염산 1,4-디하이드로피리딘 유도체의 제조 방법
ATE415389T1 (de) * 2006-05-24 2008-12-15 Cf Pharma Ltd Verfahren zur herstellung von lercanipidin
KR100808281B1 (ko) * 2006-06-30 2008-03-03 주식회사 하원정밀화학 레르카니디핀 및 그 산부가염의 제조방법
CN102020602B (zh) * 2009-09-18 2013-12-25 深圳信立泰药业股份有限公司 盐酸乐卡地平晶型及其制备方法和含有该晶型的药物组合物
WO2011161223A2 (fr) 2010-06-23 2011-12-29 Krka, Tovarna Zdravil, D.D., Novo Mesto Formes pharmaceutiques à usage oral comprenant de la lercanidipine et de l'énalapril et leurs sels pharmaceutiquement acceptables
SI2654729T1 (sl) 2010-12-24 2016-08-31 Krka, D.D., Novo Mesto Homogene farmacevtske oralne dozirne oblike, ki obsegajo lerkanidipin in enalapril ali njune farmacevtsko sprejemljive soli skupaj z organsko kislino
CN102516160B (zh) * 2011-12-16 2014-04-02 华润赛科药业有限责任公司 一种高纯盐酸乐卡地平的合成工艺
CN102558032B (zh) * 2011-12-16 2014-02-26 华润赛科药业有限责任公司 一种无定形盐酸乐卡地平及其制备方法
CN102584682A (zh) * 2011-12-31 2012-07-18 苏州二叶制药有限公司 盐酸乐卡地平的制备方法
CN109956943B (zh) * 2019-04-18 2021-07-20 合肥合源药业有限公司 一种二氢吡啶类药物中脱羧缩合杂质及其制备、控制方法

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8403866D0 (en) * 1984-02-14 1984-03-21 Recordati Chem Pharm Diphenylalkylaminoalkyl esters

Also Published As

Publication number Publication date
IL118143A (en) 2001-06-14
PT824517E (pt) 2002-12-31
EA000346B1 (ru) 1999-04-29
IN188486B (fr) 2002-10-05
HUP9801913A3 (en) 1999-01-28
NO975176D0 (no) 1997-11-11
PL323236A1 (en) 1998-03-16
KR100395441B1 (ko) 2004-02-05
RO119616B1 (ro) 2005-01-28
TW404940B (en) 2000-09-11
CZ288634B6 (cs) 2001-08-15
EE03351B1 (et) 2001-02-15
KR19990008378A (ko) 1999-01-25
MA23858A1 (fr) 1996-12-31
PL185260B1 (pl) 2003-04-30
JP4038622B2 (ja) 2008-01-30
CZ356797A3 (cs) 1998-04-15
CA2217849A1 (fr) 1996-11-14
DK0824517T3 (da) 2002-11-18
NO975176L (no) 1997-11-11
CN1184468A (zh) 1998-06-10
ATE221050T1 (de) 2002-08-15
ES2179942T3 (es) 2003-02-01
IL118143A0 (en) 1996-09-12
HU226709B1 (en) 2009-07-28
SK151497A3 (en) 1998-05-06
DZ2032A1 (fr) 2002-07-21
DE69622552T2 (de) 2003-01-23
EP0824517B1 (fr) 2002-07-24
EA199700374A1 (ru) 1998-10-29
IT1274480B (it) 1997-07-17
UA46769C2 (uk) 2002-06-17
MY113802A (en) 2002-05-31
AU694046B2 (en) 1998-07-09
HUP9801913A2 (hu) 1998-12-28
JPH11504932A (ja) 1999-05-11
ITMI950957A0 (it) 1995-05-12
BG102034A (en) 1998-04-30
WO1996035668A1 (fr) 1996-11-14
ZA963716B (en) 1996-11-20
DE69622552D1 (de) 2002-08-29
EP0824517A1 (fr) 1998-02-25
ITMI950957A1 (it) 1996-11-12
NO309423B1 (no) 2001-01-29
SA96170216B1 (ar) 2005-12-21
BG62400B1 (bg) 1999-10-29
AU5898596A (en) 1996-11-29
AR002739A1 (es) 1998-04-29
CN1101810C (zh) 2003-02-19
TNSN96069A1 (fr) 2005-03-15
BR9608374A (pt) 1999-08-24
CA2217849C (fr) 2007-09-11
NZ309059A (en) 1998-10-28
MX9708662A (es) 1998-08-30
SK283321B6 (sk) 2003-06-03

Similar Documents

Publication Publication Date Title
EG21755A (en) Process for preparing of lercanidipine hydrochloride and their use for the treatment of angina and coronary disease
HUP9600255A1 (en) Various forms of paroxetin hydrochloride and process for their preparation
NO962179D0 (no) Fremgangsmåte for fremstilling av metallocen og anvendelse derav
HUP9801836A3 (en) Guanine derivative and process for producing thereof
HUP9603112A2 (en) New pharmaceutical formulation and process for its production
HU9603484D0 (en) Pharmaceutical compositions and process for producing symptom-transduction
HU9600596D0 (en) Method of treating cardiac in flammatory disease
HUP9601492A3 (en) Benzimidazol derivatives, process for producing them and pharmaceutical use of them
HUP9801697A3 (en) Modified mp52-protein and process for producing thereof
IL124473A0 (en) Therapeutic garments for scars and a process for the preparation thereof
HUP9900947A3 (en) Process for the preparation of piperidine derivatives, intermediates and preparation thereof
HU9402832D0 (en) Imidazol-4-yl-piperidine derivatives, process for producing them and pharmaceutical use of them
EP0761718A3 (fr) Procédé pour la préparation de poly-o-hydroxyamides et de poly-o-mercaptoamides
HU9600624D0 (en) Piperidine derivatives, process for producing them and their pharmaceutical use
EP0837626A4 (fr) Clou et son procede de forgeage
EP0722949A3 (fr) Procédé de préparation de composés cyclopentadiényles
HU9502503D0 (en) 2,3-cyclic-condensed-1,4-dihydro-pyridine derivatives, process for producing them and pharmaceutical use of them
DE69615316D1 (de) Keramischer Wabenkörper und Verfahren zu dessen Herstellung
EP0761721A3 (fr) Procédé pour la préparation de poly-o-hydroxyamides et de poly-o-mercaptoamides
HK1016180A1 (en) Process for the preparation of anti-malarial drugs
EP0761719A3 (fr) Procédé pour la préparation de poly-o-hydroxyamides et de poly-o-mercaptoamides
HU9503782D0 (en) 1-oxo-2-(phenyl-sulfonyl-amino)-pentyl-piperidine derivatives, process for producing them and pharmaceutical use of them
EP0761720A3 (fr) Procédé pour la préparation de poly-o-hydroxyamides et de poly-o-mercaptoamides
NO971419L (no) Fremgangsmåte for fremstilling av 1,3-alkendioler og 3-hydroksyaldehyder
IL117191A0 (en) Process for the preparation of oxazolidinones and their use