EE04498B1 - Erütromütsiini derivaadid, nende valmistamismeetod ja neid sisaldav farmatseutiline kompositsioon - Google Patents

Erütromütsiini derivaadid, nende valmistamismeetod ja neid sisaldav farmatseutiline kompositsioon

Info

Publication number
EE04498B1
EE04498B1 EE9500080A EE9500080A EE04498B1 EE 04498 B1 EE04498 B1 EE 04498B1 EE 9500080 A EE9500080 A EE 9500080A EE 9500080 A EE9500080 A EE 9500080A EE 04498 B1 EE04498 B1 EE 04498B1
Authority
EE
Estonia
Prior art keywords
preparation
pharmaceutical composition
composition containing
erythromycin derivatives
erythromycin
Prior art date
Application number
EE9500080A
Other languages
English (en)
Estonian (et)
Other versions
EE9500080A (et
Inventor
Agouridas Constantin
Benedetti Yannick
Chantot Jean-Fran�Ois
Denis Alexis
Le Martret Odile
Original Assignee
Roussel Uclaf
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Roussel Uclaf filed Critical Roussel Uclaf
Publication of EE9500080A publication Critical patent/EE9500080A/xx
Publication of EE04498B1 publication Critical patent/EE04498B1/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
    • C07H17/08—Hetero rings containing eight or more ring members, e.g. erythromycins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oncology (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Communicable Diseases (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
EE9500080A 1994-04-08 1995-04-06 Erütromütsiini derivaadid, nende valmistamismeetod ja neid sisaldav farmatseutiline kompositsioon EE04498B1 (et)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR9404154A FR2718450B1 (fr) 1994-04-08 1994-04-08 Nouveaux dérivés de l'érythromycine, leur procédé de préparation et leur application comme médicaments.
PCT/FR1995/000441 WO1995027720A1 (fr) 1994-04-08 1995-04-06 Nouveaux derives de l'erythromycine, leur procede de preparation et leur application comme medicaments

Publications (2)

Publication Number Publication Date
EE9500080A EE9500080A (et) 1996-12-16
EE04498B1 true EE04498B1 (et) 2005-06-15

Family

ID=9461886

Family Applications (1)

Application Number Title Priority Date Filing Date
EE9500080A EE04498B1 (et) 1994-04-08 1995-04-06 Erütromütsiini derivaadid, nende valmistamismeetod ja neid sisaldav farmatseutiline kompositsioon

Country Status (49)

Country Link
US (2) US5656607A (oth)
EP (1) EP0676409B1 (oth)
JP (1) JP3000023B2 (oth)
KR (1) KR100317148B1 (oth)
CN (1) CN1059445C (oth)
AP (1) AP587A (oth)
AT (1) ATE234853T1 (oth)
AU (1) AU684939B2 (oth)
BG (1) BG61916B1 (oth)
BR (1) BR9506147A (oth)
CA (1) CA2164638C (oth)
CO (1) CO4370097A1 (oth)
CZ (1) CZ296005B6 (oth)
DE (1) DE69529934T2 (oth)
DK (1) DK0676409T3 (oth)
DZ (1) DZ1869A1 (oth)
EE (1) EE04498B1 (oth)
ES (1) ES2189820T3 (oth)
FI (1) FI111264B (oth)
FR (1) FR2718450B1 (oth)
GB (1) GB2288174A (oth)
GE (1) GEP19991836B (oth)
HR (1) HRP950217B1 (oth)
HU (1) HU215396B (oth)
IL (1) IL112954A (oth)
IS (1) IS1865B (oth)
JO (1) JO1850B1 (oth)
LV (1) LV11182B (oth)
MA (1) MA23501A1 (oth)
MD (1) MD663G2 (oth)
MY (1) MY114672A (oth)
NO (1) NO308361B1 (oth)
NZ (1) NZ284498A (oth)
OA (1) OA10200A (oth)
PE (1) PE2896A1 (oth)
PL (1) PL180837B1 (oth)
PT (1) PT676409E (oth)
RO (1) RO115634B1 (oth)
RU (1) RU2141965C1 (oth)
SA (1) SA97170757A (oth)
SI (1) SI0676409T1 (oth)
SK (1) SK284079B6 (oth)
SV (1) SV1995000018A (oth)
TN (1) TNSN95026A1 (oth)
TW (1) TW316908B (oth)
UA (1) UA44705C2 (oth)
WO (1) WO1995027720A1 (oth)
YU (1) YU49221B (oth)
ZA (1) ZA952059B (oth)

Families Citing this family (50)

* Cited by examiner, † Cited by third party
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FR2732023B1 (fr) * 1995-03-22 1997-04-30 Roussel Uclaf Nouveaux derives de l'erythromycine, leur procede de preparation et leur application comme medicaments
FR2742757B1 (fr) * 1995-12-22 1998-01-30 Roussel Uclaf Nouveaux derives de l'erythromycine, leur procede de preparation et leur application comme medicaments
FR2745289B1 (fr) * 1996-02-28 1998-05-29 Roussel Uclaf Nouveaux derives de l'acide 1(2h) quinoleine carboxylique, leur procede de preparation et leur application a la synthese de produits doues de proprietes antibiotiques
US5750510A (en) * 1997-04-04 1998-05-12 Abbott Laboratories 3-descladinose-2,3-anhydroerythromycin derivatives
JP2002502366A (ja) * 1996-05-07 2002-01-22 アボット・ラボラトリーズ ３―デスクラジノース―２，３―無水エリスロマイシン誘導体
FR2748746B1 (fr) * 1996-05-14 1998-08-14 Hoechst Marion Roussel Inc Nouveau procede d'isomerisation du radical methyle en 10 de derives de l'erythromycine
FR2751656B1 (fr) * 1996-07-24 1998-10-16 Hoechst Marion Roussel Inc Nouveaux derives de l'erythromycine, leur procede de preparation et leur application comme medicaments
UA51730C2 (uk) * 1996-09-04 2002-12-16 Ебботт Лабораторіз 6-o-заміщені кетоліди з антибактеріальною активністю, спосіб їх одержання (варіанти), фармацевтична композиція та спосіб регулювання бактеріальної інфекції у ссавців
DE69733723T2 (de) * 1996-09-04 2006-04-20 Abbott Laboratories, Abbott Park 6-o-Substituierte Ketoliden mit antibakteriellen Wirkung
FR2757168B1 (fr) * 1996-12-12 1999-06-11 Hoechst Marion Roussel Inc Nouveaux derives de l'erythromycine, leur procede de preparation et leur application comme medicaments
FR2760017B1 (fr) * 1997-02-27 1999-04-30 Hoechst Marion Roussel Inc Nouveaux derives de l'erytromycine, leur procede de preparation et leur application comme medicaments
WO1998040392A1 (fr) * 1997-03-10 1998-09-17 Taisho Pharmaceutical Co., Ltd. Derives d'erythromycine a
US6140479A (en) * 1997-03-24 2000-10-31 Taisho Pharmaceuticals Co., Ltd. Erythromycin a derivatives
WO1998051696A1 (en) * 1997-05-09 1998-11-19 Pfizer Products Inc. Erythromycin derivatives
US5922683A (en) * 1997-05-29 1999-07-13 Abbott Laboratories Multicyclic erythromycin derivatives
CZ9904388A3 (cs) * 1997-06-11 2002-10-16 Pfizer Products Inc. 9-Oximové deriváty erythromycinu
FR2771008B1 (fr) * 1997-11-17 2000-04-28 Hoechst Marion Roussel Inc Utilisation des ketolides pour la preparation de compositions pharmaceutiques destinees a prevenir les complications thrombotiques arterielles liees a l'atherosclerose
AP1060A (en) * 1998-01-02 2002-04-23 Pfizer Prod Inc Novel erythromycin derivatives.
HRP980189B1 (en) * 1998-04-06 2004-04-30 Pliva Pharm & Chem Works Novel 15-membered lactams ketolides
WO2000017218A1 (en) 1998-09-22 2000-03-30 Pfizer Products Inc. Carbamate and carbazate ketolide antibiotics
FR2786188B1 (fr) * 1998-11-24 2002-10-31 Hoechst Marion Roussel Inc Nouveaux derives de l'erythromycine, leur procede de preparation et leur applicaion comme medicaments
EP1749832A3 (en) * 1998-12-10 2008-03-26 Pfizer Products Incorporated Carbamate and carbazate ketolide antibiotics
EP1298138B1 (en) * 1998-12-10 2006-11-02 Pfizer Products Inc. Carbamate and Carbazate Ketolide Antibiotics
TR200102129T2 (tr) 1998-12-10 2002-01-21 Pfizer Products Inc. Karbamat ve karbazat ketolid antibiyotikleri.
FR2789392B1 (fr) * 1999-02-04 2001-10-05 Hoechst Marion Roussel Inc Nouveaux derives de l'erythromycine, leur procede de preparation et leur application comme medicaments
US6054435A (en) * 1999-03-19 2000-04-25 Abbott Laboratories 6-O-substituted macrolides having antibacterial activity
ID30547A (id) * 1999-04-16 2001-12-20 Kosan Biosciences Inc Zat anti-infeksi makrolida
US6590083B1 (en) 1999-04-16 2003-07-08 Ortho-Mcneil Pharmaceutical, Inc. Ketolide antibacterials
IL145976A0 (en) 1999-04-16 2002-07-25 Ortho Mcneil Pharm Inc Ketolide antibacterials
EA200100983A1 (ru) * 1999-05-24 2002-10-31 Пфайзер Продактс Инк. Производные 13-метилэритромицина
WO2003004509A2 (en) * 2001-07-03 2003-01-16 Chiron Corporation C12 modified erythromycin macrolides and ketolides having antibacterial activity
KR101035043B1 (ko) 2002-07-01 2011-05-19 아르키온 라이프 사이언씨즈 엘엘씨 글루코사민 및 ｎ-아세틸글루코사민의 제조를 위한 물질및 공정
ES2552682T3 (es) 2003-03-10 2015-12-01 Merck Sharp & Dohme Corp. Agentes antibacterianos novedosos
US7163924B2 (en) * 2003-04-25 2007-01-16 Chiron Corporation Ketolide derivatives
US7332476B2 (en) * 2003-04-25 2008-02-19 Novartis Ag Pyridyl substituted ketolide antibiotics
CN105732745A (zh) 2007-10-25 2016-07-06 森普拉制药公司 大环内酯类抗菌剂的制备方法
AU2009308182B2 (en) * 2008-10-24 2016-05-19 Cempra Pharmaceuticals, Inc. Biodefenses using triazole-containing macrolides
US9937194B1 (en) 2009-06-12 2018-04-10 Cempra Pharmaceuticals, Inc. Compounds and methods for treating inflammatory diseases
US9480679B2 (en) 2009-09-10 2016-11-01 Cempra Pharmaceuticals, Inc. Methods for treating malaria, tuberculosis and MAC diseases
DK2550286T3 (en) 2010-03-22 2016-02-29 Cempra Pharmaceuticals Inc CRYSTALLINE FORMS OF A MACROLID AND APPLICATIONS THEREOF
CN105198944B (zh) 2010-05-20 2018-06-01 森普拉制药公司 制备大环内酯和酮内酯及其中间体的方法
EP2613630A4 (en) 2010-09-10 2014-01-15 Cempra Pharmaceuticals Inc HYDROGEN BOND FOR THE PREPARATION OF FLUOROCHETOLIDES FOR THE TREATMENT OF DISEASES
MX2014011537A (es) 2012-03-27 2015-02-10 Cempra Pharmaceuticals Inc Formulaciones parenterales para la administracion de antibioticos macrolidos.
HK1217665A1 (zh) 2013-03-14 2017-01-20 森普拉制药公司 用於治療呼吸道疾病的方法及其製劑
RU2015138797A (ru) 2013-03-15 2017-04-24 Семпра Фармасьютикалс, Инк. Конвергентные способы получения макролидных антибактериальных агентов
US9982005B2 (en) 2013-04-04 2018-05-29 President And Fellows Of Harvard College Macrolides and methods of their preparation and use
US10633407B2 (en) 2014-10-08 2020-04-28 President And Fellows Of Harvard College 14-membered ketolides and methods of their preparation and use
JP2018509452A (ja) 2015-03-25 2018-04-05 プレジデント アンド フェローズ オブ ハーバード カレッジ 修飾デソサミン糖をもつマクロライドおよびその使用
MD1222Z (ro) * 2017-05-31 2018-08-31 ИНСТИТУТ ЭЛЕКТРОННОЙ ИНЖЕНЕРИИ И НАНОТЕХНОЛОГИЙ "D. Ghitu" АНМ Procedeu de tratare a materialului săditor al florilor înainte de plantare
JP7199722B2 (ja) 2019-12-25 2023-01-06 旭精工株式会社 硬貨搬送振分機構及びそれを備えた硬貨識別搬送装置

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US3868414A (en) * 1973-01-22 1975-02-25 Merck & Co Inc Tetrahydrofluorene carboxylic acids and related compounds
AT342770B (de) * 1975-04-07 1978-04-25 Thomae Gmbh Dr K Verfahren zur herstellung neuer erythromycinderivate
DE2842759A1 (de) * 1978-09-30 1980-04-10 Merck Patent Gmbh Basische aether, diese enthaltende pharmazeutische zubereitungen und verfahren zu ihrer herstellung
IL114589A (en) * 1990-11-21 1999-12-22 Roussel Uclaf Intermediates for the preparation of erythromycin derivatives
FR2692579B1 (fr) * 1992-06-19 1995-06-02 Roussel Uclaf Nouveaux dérivés de la picromycine, leur procédé de préparation et leur application comme médicaments.
US5527780A (en) * 1992-11-05 1996-06-18 Roussel Uclaf Erythromycin derivatives
FR2697524B1 (fr) * 1992-11-05 1994-12-23 Roussel Uclaf Nouveaux dérivés de l'érythromycine, leur procédé de préparation et leur application comme médicaments.
HRP930014A2 (en) * 1993-01-08 1994-08-31 Pliva Pharm & Chem Works 9-deoxo-9a-aza-11-deoxy-9a-homoeritromycin a 9a, 11-cyclic carbamates
FR2702480B1 (fr) * 1993-03-09 1995-04-28 Roussel Uclaf Nouveaux dérivés de l'érythromycine, leur procédé de préparation et leur application comme médicaments.

Also Published As

Publication number Publication date
HUT73772A (en) 1996-09-30
FI955913A7 (fi) 1995-12-08
CZ322395A3 (en) 1996-08-14
BG100150A (bg) 1996-06-28
CZ296005B6 (cs) 2005-12-14
HRP950217B1 (en) 2004-06-30
HU9503505D0 (en) 1996-02-28
SI0676409T1 (en) 2003-06-30
NZ284498A (en) 1997-07-27
DZ1869A1 (fr) 2002-02-17
LV11182A (lv) 1996-04-20
HU215396B (hu) 1998-12-28
AU2310795A (en) 1995-10-30
ATE234853T1 (de) 2003-04-15
AP587A (en) 1997-04-29
UA44705C2 (uk) 2002-03-15
SV1995000018A (es) 1997-10-24
WO1995027720A1 (fr) 1995-10-19
CA2164638C (fr) 2003-12-30
PL311871A1 (en) 1996-03-18
JP3000023B2 (ja) 2000-01-17
FR2718450A1 (fr) 1995-10-13
GB9506856D0 (en) 1995-05-24
EP0676409B1 (fr) 2003-03-19
JO1850B1 (en) 1995-12-27
MA23501A1 (fr) 1995-12-31
IS4309A (is) 1995-11-17
BR9506147A (pt) 1996-04-16
JPH07278177A (ja) 1995-10-24
LV11182B (en) 1997-04-20
FI955913A0 (fi) 1995-12-08
ES2189820T3 (es) 2003-07-16
YU49221B (sh) 2004-11-25
CA2164638A1 (fr) 1995-10-19
DK0676409T3 (da) 2003-06-23
PL180837B1 (pl) 2001-04-30
BG61916B1 (bg) 1998-09-30
HRP950217A2 (en) 1997-08-31
US5760233A (en) 1998-06-02
RO115634B1 (ro) 2000-04-28
AU684939B2 (en) 1998-01-08
IL112954A0 (en) 1995-06-29
SK154695A3 (en) 1996-10-02
AP9500743A0 (en) 1995-07-31
GEP19991836B (en) 1999-11-05
NO954942L (no) 1996-02-07
CN1126997A (zh) 1996-07-17
MD663G2 (ro) 1997-07-31
SA97170757A (ar) 2005-12-03
YU21695A (sh) 1997-12-05
MD663F1 (ro) 1997-01-31
IS1865B (is) 2003-05-02
NO954942D0 (no) 1995-12-06
PT676409E (pt) 2003-08-29
OA10200A (fr) 1996-12-18
TW316908B (oth) 1997-10-01
MY114672A (en) 2002-12-31
CO4370097A1 (es) 1996-10-07
FR2718450B1 (fr) 1997-01-10
ZA952059B (en) 1996-03-13
RU2141965C1 (ru) 1999-11-27
NO308361B1 (no) 2000-09-04
EP0676409A1 (fr) 1995-10-11
US5656607A (en) 1997-08-12
EE9500080A (et) 1996-12-16
TNSN95026A1 (fr) 1996-02-06
KR100317148B1 (ko) 2002-06-22
SK284079B6 (sk) 2004-09-08
DE69529934D1 (de) 2003-04-24
DE69529934T2 (de) 2003-09-04
CN1059445C (zh) 2000-12-13
PE2896A1 (es) 1996-02-12
IL112954A (en) 2000-07-16
GB2288174A (en) 1995-10-11
FI111264B (fi) 2003-06-30

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