|
EP0781138B1
(en)
|
1994-08-29 |
2008-05-21 |
Wake Forest University |
Lipid analogs for treating viral infections
|
|
US7135584B2
(en)
|
1995-08-07 |
2006-11-14 |
Wake Forest University |
Lipid analogs for treating viral infections
|
|
DE69709671T2
(de)
*
|
1996-10-18 |
2002-08-22 |
Vertex Pharmaceuticals Inc., Cambridge |
Inhibitoren von serinproteasen, insbesondere von ns3-protease des hepatitis-c-virus
|
|
GB9707659D0
(en)
*
|
1997-04-16 |
1997-06-04 |
Peptide Therapeutics Ltd |
Hepatitis C NS3 Protease inhibitors
|
|
IL134233A0
(en)
*
|
1997-08-11 |
2001-04-30 |
Boehringer Ingelheim Ca Ltd |
Hepatitis c inhibitor peptide analogues
|
|
NZ503262A
(en)
*
|
1997-08-11 |
2002-10-25 |
Boehringer Ingelheim Ca Ltd |
Hepatitis C NS3 protease inhibitor peptides and peptide analogues
|
|
US6767991B1
(en)
|
1997-08-11 |
2004-07-27 |
Boehringer Ingelheim (Canada) Ltd. |
Hepatitis C inhibitor peptides
|
|
GB9806815D0
(en)
*
|
1998-03-30 |
1998-05-27 |
Hoffmann La Roche |
Amino acid derivatives
|
|
WO1999050230A1
(en)
*
|
1998-03-31 |
1999-10-07 |
Vertex Pharmaceuticals Incorporated |
Inhibitors of serine proteases, particularly hepatitis c virus ns3 protease
|
|
GB9809664D0
(en)
*
|
1998-05-06 |
1998-07-01 |
Hoffmann La Roche |
a-Ketoamide derivatives
|
|
GB9812523D0
(en)
*
|
1998-06-10 |
1998-08-05 |
Angeletti P Ist Richerche Bio |
Peptide inhibitors of hepatitis c virus ns3 protease
|
|
US6323180B1
(en)
|
1998-08-10 |
2001-11-27 |
Boehringer Ingelheim (Canada) Ltd |
Hepatitis C inhibitor tri-peptides
|
|
AR022061A1
(es)
*
|
1998-08-10 |
2002-09-04 |
Boehringer Ingelheim Ca Ltd |
Peptidos inhibidores de la hepatitis c, una composicion farmaceutica que los contiene, el uso de los mismos para preparar una composicion farmaceutica, el uso de un producto intermedio para la preparacion de estos peptidos y un procedimiento para la preparacion de un peptido analogo de los mismos.
|
|
JP2002538151A
(ja)
|
1999-03-02 |
2002-11-12 |
ベーリンガー インゲルハイム ファーマシューティカルズ インコーポレイテッド |
カテプシンの可逆的インヒビターとして有用な化合物
|
|
US6608027B1
(en)
|
1999-04-06 |
2003-08-19 |
Boehringer Ingelheim (Canada) Ltd |
Macrocyclic peptides active against the hepatitis C virus
|
|
UA74546C2
(en)
*
|
1999-04-06 |
2006-01-16 |
Boehringer Ingelheim Ca Ltd |
Macrocyclic peptides having activity relative to hepatitis c virus, a pharmaceutical composition and use of the pharmaceutical composition
|
|
WO2001002424A2
(en)
*
|
1999-07-07 |
2001-01-11 |
Du Pont Pharmaceuticals Company |
Peptide boronic acid inhibitors of hepatitis c virus protease
|
|
WO2001007407A1
(en)
*
|
1999-07-26 |
2001-02-01 |
Bristol-Myers Squibb Pharma Company |
Lactam inhibitors of hepatitis c virus ns3 protease
|
|
US7122627B2
(en)
|
1999-07-26 |
2006-10-17 |
Bristol-Myers Squibb Company |
Lactam inhibitors of Hepatitis C virus NS3 protease
|
|
US6420364B1
(en)
|
1999-09-13 |
2002-07-16 |
Boehringer Ingelheim Pharmaceuticals, Inc. |
Compound useful as reversible inhibitors of cysteine proteases
|
|
US7026469B2
(en)
|
2000-10-19 |
2006-04-11 |
Wake Forest University School Of Medicine |
Compositions and methods of double-targeting virus infections and cancer cells
|
|
CA2390349A1
(en)
*
|
1999-12-03 |
2001-06-07 |
Bristol-Myers Squibb Pharma Company |
Alpha-ketoamide inhibitors of hepatitis c virus ns3 protease
|
|
ATE299494T1
(de)
*
|
1999-12-07 |
2005-07-15 |
Theravance Inc |
Carbamat-derivate als muscarin-rezeptor antonisten
|
|
WO2001064678A2
(en)
*
|
2000-02-29 |
2001-09-07 |
Bristol-Myers Squibb Pharma Company |
Inhibitors of hepatitis c virus ns3 protease
|
|
WO2001074768A2
(en)
*
|
2000-04-03 |
2001-10-11 |
Vertex Pharmaceuticals Incorporated |
Inhibitors of serine proteases, particularly hepatitis c virus ns3 protease
|
|
AU2006202124B2
(en)
*
|
2000-04-03 |
2010-01-21 |
Vertex Pharmaceuticals Incorporated |
Inhibitors of Serine Proteases, Particularly Hepatitis C Virus NS3 Protease
|
|
PL359359A1
(en)
|
2000-04-05 |
2004-08-23 |
Schering Corporation |
Macrocyclic ns3-serine protease inhibitors of hepatitis c virus comprising n-cyclic p2 moieties
|
|
PL358591A1
(en)
|
2000-04-19 |
2004-08-09 |
Schering Corporation |
Macrocyclic ns3-serine protease inhibitors of hepatitis c virus comprising alkyl and aryl alanine p2 moieties
|
|
PE20011350A1
(es)
|
2000-05-19 |
2002-01-15 |
Vertex Pharma |
PROFARMACO DE UN INHIBIDOR DE ENZIMA CONVERTIDORA DE INTERLEUCINA-1ß (ICE)
|
|
MY164523A
(en)
|
2000-05-23 |
2017-12-29 |
Univ Degli Studi Cagliari |
Methods and compositions for treating hepatitis c virus
|
|
EA007867B1
(ru)
|
2000-05-26 |
2007-02-27 |
Айденикс (Кайман) Лимитед |
Композиции для лечения флавивирусных и пестивирусных инфекций и способы их применения
|
|
US20020007324A1
(en)
*
|
2000-06-09 |
2002-01-17 |
Centner David J. |
System and method for effectively conducting transactions between buyers and suppliers
|
|
US7244721B2
(en)
*
|
2000-07-21 |
2007-07-17 |
Schering Corporation |
Peptides as NS3-serine protease inhibitors of hepatitis C virus
|
|
HU229997B1
(en)
*
|
2000-07-21 |
2015-04-28 |
Dendreon Corp San Diego |
Peptides as ns3-serine protease inhibitors of hepatitis c virus
|
|
AR029851A1
(es)
|
2000-07-21 |
2003-07-16 |
Dendreon Corp |
Nuevos peptidos como inhibidores de ns3-serina proteasa del virus de hepatitis c
|
|
CZ2003195A3
(cs)
|
2000-07-21 |
2003-04-16 |
Schering Corporation |
Peptidové inhibitory serinové proteázy NS3 a farmaceutický prostředek
|
|
AR034127A1
(es)
*
|
2000-07-21 |
2004-02-04 |
Schering Corp |
Imidazolidinonas como inhibidores de ns3-serina proteasa del virus de hepatitis c, composicion farmaceutica, un metodo para su preparacion, y el uso de las mismas para la manufactura de un medicamento
|
|
SV2003000617A
(es)
*
|
2000-08-31 |
2003-01-13 |
Lilly Co Eli |
Inhibidores de la proteasa peptidomimetica ref. x-14912m
|
|
US20040106539A1
(en)
*
|
2000-10-12 |
2004-06-03 |
Ulrich Schubert |
Agents for the treatment of viral infections
|
|
US20030087873A1
(en)
|
2000-10-18 |
2003-05-08 |
Lieven Stuyver |
Modified nucleosides for the treatment of viral infections and abnormal cellular proliferation
|
|
US7309696B2
(en)
|
2000-10-19 |
2007-12-18 |
Wake Forest University |
Compositions and methods for targeting cancer cells
|
|
US6846806B2
(en)
|
2000-10-23 |
2005-01-25 |
Bristol-Myers Squibb Company |
Peptide inhibitors of Hepatitis C virus NS3 protein
|
|
HUP0303436A2
(hu)
*
|
2000-12-12 |
2004-01-28 |
Schering Corp. |
Diaril-peptidek mint a hepatitis C vírus NS3-szerin proteáz inhibitorai, ezeket tartalmazó gyógyszerkészítmények és alkalmazásuk
|
|
US6653295B2
(en)
|
2000-12-13 |
2003-11-25 |
Bristol-Myers Squibb Company |
Inhibitors of hepatitis C virus NS3 protease
|
|
WO2002048157A2
(en)
*
|
2000-12-13 |
2002-06-20 |
Bristol-Myers Squibb Pharma Company |
Imidazolidinones and their related derivatives as hepatitis c virus ns3 protease inhibitors
|
|
NZ526703A
(en)
|
2001-01-22 |
2004-12-24 |
Merck & Co Inc |
Nucleoside derivatives as inhibitors of RNA-dependent RNA viral polymerase
|
|
CA2449504A1
(en)
|
2001-07-11 |
2003-01-23 |
Vertex Pharmaceuticals Incorporated |
Bridged bicyclic serine protease inhibitors
|
|
KR100871648B1
(ko)
|
2001-08-31 |
2008-12-03 |
톰슨 라이센싱 |
조건부 액세스 시스템을 구현하는 방법, 컨텐트를 전송하는 방법 및 그 장치 및 컨텐트를 수신하고 처리하는 방법 및 그 장치
|
|
WO2003026589A2
(en)
|
2001-09-28 |
2003-04-03 |
Idenix (Cayman) Limited |
Methods and compositions for treating hepatitis c virus using 4'-modified nucleosides
|
|
EP1441720B8
(en)
*
|
2001-10-24 |
2012-03-28 |
Vertex Pharmaceuticals Incorporated |
Inhibitors of serine protease, particularly hepatitis c virus ns3-ns4a protease, incorporating a fused ring system
|
|
MY151199A
(en)
*
|
2001-11-02 |
2014-04-30 |
Rigel Pharmaceuticals Inc |
Substituted diphenyl heterocycles useful for treating hcv infection
|
|
CA2473070C
(en)
|
2002-01-23 |
2009-10-13 |
Schering Corporation |
Proline compounds as ns3-serine protease inhibitors for use in treatment of hepatites c virus infection
|
|
US7119072B2
(en)
|
2002-01-30 |
2006-10-10 |
Boehringer Ingelheim (Canada) Ltd. |
Macrocyclic peptides active against the hepatitis C virus
|
|
US6642204B2
(en)
|
2002-02-01 |
2003-11-04 |
Boehringer Ingelheim International Gmbh |
Hepatitis C inhibitor tri-peptides
|
|
US7091184B2
(en)
|
2002-02-01 |
2006-08-15 |
Boehringer Ingelheim International Gmbh |
Hepatitis C inhibitor tri-peptides
|
|
US7273885B2
(en)
*
|
2002-04-11 |
2007-09-25 |
Vertex Pharmaceuticals Incorporated |
Inhibitors of serine proteases, particularly HCV NS3-NS4A protease
|
|
PL213029B1
(pl)
|
2002-05-20 |
2012-12-31 |
Bristol Myers Squibb Co |
Podstawiona pochodna cykloalkilowa, zawierajaca ja kompozycja oraz ich zastosowanie
|
|
MY140680A
(en)
|
2002-05-20 |
2010-01-15 |
Bristol Myers Squibb Co |
Hepatitis c virus inhibitors
|
|
PL215228B1
(pl)
*
|
2002-05-20 |
2013-11-29 |
Bristol Myers Squibb Co |
Zwiazki tripeptydowe, ich zastosowanie i kompozycja farmaceutyczna je zawierajaca oraz jej zastosowanie
|
|
PL211889B1
(pl)
|
2002-05-20 |
2012-07-31 |
Bristol Myers Squibb Co |
Pochodna heterocyklosulfonamidowa, kompozycja ją zawierająca oraz ich zastosowanie
|
|
CN104193791A
(zh)
|
2002-06-28 |
2014-12-10 |
埃迪尼克斯医药公司 |
用于治疗黄病毒感染的修饰的2’和3’-核苷前药
|
|
AU2003277891A1
(en)
*
|
2002-09-23 |
2004-04-08 |
Medivir Ab |
Hcv ns-3 serine protease inhibitors
|
|
US20050075279A1
(en)
|
2002-10-25 |
2005-04-07 |
Boehringer Ingelheim International Gmbh |
Macrocyclic peptides active against the hepatitis C virus
|
|
CA2506129C
(en)
|
2002-11-15 |
2015-02-17 |
Idenix (Cayman) Limited |
2'-branched nucleosides and flaviviridae mutation
|
|
AU2004230946A1
(en)
*
|
2003-04-11 |
2004-10-28 |
Vertex Pharmaceuticals, Incorporated |
Inhibitors of serine proteases, particularly HCV NS3-NS4A protease
|
|
EP1613620A1
(en)
|
2003-04-11 |
2006-01-11 |
Vertex Pharmaceuticals Incorporated |
Inhibitors of serine proteases, particularly hcv ns3-ns4a protease
|
|
AU2011203054B2
(en)
*
|
2003-04-11 |
2012-04-26 |
Vertex Pharmaceuticals, Incorporated |
Inhibitors of Serine Proteases, Particularly HCV NS3-NS4A Protease
|
|
WO2004099165A2
(en)
|
2003-05-02 |
2004-11-18 |
Rigel Pharmaceuticals, Inc. |
Heterocyclic compounds and hydro isomers thereof
|
|
CN1791599A
(zh)
|
2003-05-21 |
2006-06-21 |
贝林格尔.英格海姆国际有限公司 |
丙型肝炎抑制剂化合物
|
|
PT3521297T
(pt)
|
2003-05-30 |
2022-03-18 |
Gilead Pharmasset Llc |
Análogos de nucleosídeo fluorados modificados
|
|
CN1852920B
(zh)
*
|
2003-07-18 |
2010-12-15 |
沃泰克斯药物股份有限公司 |
丝氨酸蛋白酶抑制剂、特别是hcv ns3-ns4a蛋白酶抑制剂
|
|
PL1658302T3
(pl)
|
2003-07-25 |
2011-03-31 |
Idenix Pharmaceuticals Inc |
Analogi nukleozydów purynowych do leczenia chorób spowodowanych przez Flaviviridae obejmujących zapalenie wątroby typu C
|
|
US7223745B2
(en)
|
2003-08-14 |
2007-05-29 |
Cephalon, Inc. |
Proteasome inhibitors and methods of using the same
|
|
US7576206B2
(en)
|
2003-08-14 |
2009-08-18 |
Cephalon, Inc. |
Proteasome inhibitors and methods of using the same
|
|
EP1664090A2
(en)
|
2003-08-26 |
2006-06-07 |
Schering Corporation |
Novel peptidomimetic ns3-serine protease inhibitors of hepatitis c virus
|
|
TWI359147B
(en)
|
2003-09-05 |
2012-03-01 |
Vertex Pharma |
Inhibitors of serine proteases, particularly hcv n
|
|
WO2005028502A1
(en)
*
|
2003-09-18 |
2005-03-31 |
Vertex Pharmaceuticals, Incorporated |
Inhibitors of serine proteases, particularly hcv ns3-ns4a protease
|
|
ATE500264T1
(de)
|
2003-09-22 |
2011-03-15 |
Boehringer Ingelheim Int |
Makrozyklische peptide mit wirkung gegen das hepatitis-c-virus
|
|
ATE497505T1
(de)
|
2003-09-26 |
2011-02-15 |
Schering Corp |
Makrocyclische inhibitoren der ns3-serinprotease des hepatitis-c-virus
|
|
CN101857631A
(zh)
|
2003-10-10 |
2010-10-13 |
沃泰克斯药物股份有限公司 |
丝氨酸蛋白酶、特别是hcv ns3-ns4a蛋白酶的抑制剂
|
|
CA2540858C
(en)
|
2003-10-14 |
2009-12-08 |
Intermune, Inc. |
Macrocyclic carboxylic acids and acylsulfonamides as inhibitors of hcv replication
|
|
JP4890254B2
(ja)
|
2003-10-27 |
2012-03-07 |
バーテックス ファーマシューティカルズ インコーポレイテッド |
Hcvns3−ns4aプロテアーゼ耐性突然変異体
|
|
WO2005043118A2
(en)
|
2003-10-27 |
2005-05-12 |
Vertex Pharmaceuticals Incorporated |
Drug discovery method
|
|
EP1944042A1
(en)
|
2003-10-27 |
2008-07-16 |
Vertex Pharmceuticals Incorporated |
Combinations for HCV treatment
|
|
US7132504B2
(en)
|
2003-11-12 |
2006-11-07 |
Bristol-Myers Squibb Company |
Hepatitis C virus inhibitors
|
|
US7309708B2
(en)
|
2003-11-20 |
2007-12-18 |
Birstol-Myers Squibb Company |
Hepatitis C virus inhibitors
|
|
MXPA06005683A
(es)
|
2003-11-20 |
2006-12-14 |
Schering Corp |
Inhibidores despeptidizados de la proteasa ns3 del virus de la hepatitis c.
|
|
US7135462B2
(en)
|
2003-11-20 |
2006-11-14 |
Bristol-Myers Squibb Company |
Hepatitis C virus inhibitors
|
|
GB0500020D0
(en)
|
2005-01-04 |
2005-02-09 |
Novartis Ag |
Organic compounds
|
|
ES2358333T3
(es)
|
2004-01-21 |
2011-05-09 |
Boehringer Ingelheim International Gmbh |
Péptidos macrocíclicos con acción contra el virus de la hepatitis c.
|
|
EP1713822B1
(en)
*
|
2004-01-30 |
2010-03-17 |
Medivir AB |
Hcv ns-3 serine protease inhibitors
|
|
CA2554999A1
(en)
|
2004-02-04 |
2005-08-25 |
Vertex Pharmaceuticals Incorporated |
Inhibitors of serine proteases, particularly hcv ns3-ns4a protease
|
|
SI1719773T1
(sl)
|
2004-02-24 |
2009-08-31 |
Japan Tobacco Inc |
Kondenzirane heterotetraciklične spojine in njihova uporaba kot inhibitorji polimeraze HCV
|
|
US20070049593A1
(en)
|
2004-02-24 |
2007-03-01 |
Japan Tobacco Inc. |
Tetracyclic fused heterocyclic compound and use thereof as HCV polymerase inhibitor
|
|
ATE434621T1
(de)
|
2004-02-27 |
2009-07-15 |
Schering Corp |
Neue verbindungen als inhibitoren der ns3- serinprotease des hepatitis-c-virus
|
|
US7816326B2
(en)
|
2004-02-27 |
2010-10-19 |
Schering Corporation |
Sulfur compounds as inhibitors of hepatitis C virus NS3 serine protease
|
|
AU2005222055A1
(en)
|
2004-02-27 |
2005-09-22 |
Schering Corporation |
Compounds as inhibitors of hepatitis C virus NS3 serine protease
|
|
EP1730110B9
(en)
|
2004-02-27 |
2011-11-02 |
Schering Corporation |
Sulfur compounds as inhibitors of hepatitis c virus ns3 serine protease
|
|
CN1950393A
(zh)
|
2004-02-27 |
2007-04-18 |
先灵公司 |
丙型肝炎病毒ns3蛋白酶的抑制剂
|
|
PL2399916T3
(pl)
*
|
2004-03-12 |
2015-06-30 |
Vertex Pharma |
Sposoby i związki pośrednie do wytwarzania acetali asparaginowych jako inhibitorów kaspazy
|
|
JP5616569B2
(ja)
|
2004-04-15 |
2014-10-29 |
オニキス セラピューティクス, インク.Onyx Therapeutics, Inc. |
酵素阻害のための化合物
|
|
US8198270B2
(en)
*
|
2004-04-15 |
2012-06-12 |
Onyx Therapeutics, Inc. |
Compounds for proteasome enzyme inhibition
|
|
EP2030981B1
(en)
*
|
2004-05-10 |
2014-07-09 |
Onyx Therapeutics, Inc. |
Compounds for proteasome enzyme inhibition
|
|
WO2005113581A1
(en)
|
2004-05-20 |
2005-12-01 |
Schering Corporation |
Substituted prolines as inhibitors of hepatitis c virus ns3 serine protease
|
|
PL1778702T3
(pl)
|
2004-07-16 |
2011-12-30 |
Gilead Sciences Inc |
Związki przeciwwirusowe
|
|
UY29016A1
(es)
|
2004-07-20 |
2006-02-24 |
Boehringer Ingelheim Int |
Analogos de dipeptidos inhibidores de la hepatitis c
|
|
CA2573346C
(en)
|
2004-07-20 |
2011-09-20 |
Boehringer Ingelheim International Gmbh |
Hepatitis c inhibitor peptide analogs
|
|
CN101023094B
(zh)
|
2004-07-21 |
2011-05-18 |
法莫赛特股份有限公司 |
烷基取代的2-脱氧-2-氟代-d-呋喃核糖基嘧啶和嘌呤及其衍生物的制备
|
|
KR20070085227A
(ko)
*
|
2004-08-09 |
2007-08-27 |
앨리오스 바이오파마 인크. |
합성 초글리코실화, 프로테아제 저항성 폴리펩티드 변이체,경구 제제 및 이를 이용한 방법
|
|
US7597884B2
(en)
*
|
2004-08-09 |
2009-10-06 |
Alios Biopharma, Inc. |
Hyperglycosylated polypeptide variants and methods of use
|
|
EP1797111B1
(en)
|
2004-08-27 |
2011-06-22 |
Schering Corporation |
Acylsulfonamide compounds as inhibitors of hepatitis c virus ns3 serine protease
|
|
EP1809301B1
(en)
|
2004-09-14 |
2019-11-06 |
Gilead Pharmasset LLC |
2-fluoro-2-alkyl-substituted d-ribonolactone intermediates
|
|
SG155967A1
(en)
|
2004-10-01 |
2009-10-29 |
Vertex Pharma |
Hcv ns3-ns4a protease inhibition
|
|
US7659263B2
(en)
|
2004-11-12 |
2010-02-09 |
Japan Tobacco Inc. |
Thienopyrrole compound and use thereof as HCV polymerase inhibitor
|
|
US7323447B2
(en)
|
2005-02-08 |
2008-01-29 |
Bristol-Myers Squibb Company |
Hepatitis C virus inhibitors
|
|
US7468383B2
(en)
|
2005-02-11 |
2008-12-23 |
Cephalon, Inc. |
Proteasome inhibitors and methods of using the same
|
|
US7592336B2
(en)
|
2005-05-10 |
2009-09-22 |
Bristol-Myers Squibb Company |
Hepatitis C virus inhibitors
|
|
EA016071B1
(ru)
|
2005-05-13 |
2012-01-30 |
Вирокем Фарма Инк. |
Соединения и способы лечения или предотвращения флавивирусных инфекций
|
|
WO2006127289A1
(en)
*
|
2005-05-20 |
2006-11-30 |
Valeant Research & Development |
Treatment of hcv with subtherapeutic doses of ribavirin
|
|
NZ563365A
(en)
|
2005-06-02 |
2011-02-25 |
Schering Corp |
Combination of HCV protease inhibitors with a surfactant
|
|
US20060276404A1
(en)
*
|
2005-06-02 |
2006-12-07 |
Anima Ghosal |
Medicaments and methods combining a HCV protease inhibitor and an AKR competitor
|
|
US20070237818A1
(en)
*
|
2005-06-02 |
2007-10-11 |
Malcolm Bruce A |
Controlled-release formulation of HCV protease inhibitor and methods using the same
|
|
NZ563361A
(en)
|
2005-06-02 |
2011-02-25 |
Schering Corp |
HCV protease inhibitors in combination with food
|
|
AR054778A1
(es)
|
2005-06-17 |
2007-07-18 |
Novartis Ag |
Uso de sangliferina en hcv
|
|
US7608592B2
(en)
*
|
2005-06-30 |
2009-10-27 |
Virobay, Inc. |
HCV inhibitors
|
|
US7601686B2
(en)
|
2005-07-11 |
2009-10-13 |
Bristol-Myers Squibb Company |
Hepatitis C virus inhibitors
|
|
EP1924594A2
(en)
|
2005-07-25 |
2008-05-28 |
Intermune, Inc. |
Novel macrocyclic inhibitors of hepatitis c virus replication
|
|
PE20070210A1
(es)
|
2005-07-29 |
2007-04-16 |
Tibotec Pharm Ltd |
Compuestos macrociclicos como inhibidores del virus de hepatitis c
|
|
SI1919898T1
(sl)
|
2005-07-29 |
2011-05-31 |
Tibotec Pharm Ltd |
Makrociklični inhibitorji virusa hepatitisa C
|
|
AR057704A1
(es)
|
2005-07-29 |
2007-12-12 |
Tibotec Pharm Ltd |
Inhibidores macrociclicos del virus de la hepatitis c, composicion farmaceutica y proceso de preparacion del compuesto
|
|
EP1912996B1
(en)
|
2005-07-29 |
2012-06-20 |
Janssen R&D Ireland |
Macrocyclic inhibitors of hepatitis c virus
|
|
CN101273028B
(zh)
|
2005-07-29 |
2013-08-21 |
泰博特克药品有限公司 |
丙型肝炎病毒的大环抑制剂
|
|
JO2768B1
(en)
|
2005-07-29 |
2014-03-15 |
تيبوتيك فارماسيوتيكالز ليمتد |
Large cyclic inhibitors of hepatitis C virus
|
|
HRP20110885T1
(hr)
|
2005-07-29 |
2011-12-31 |
Tibotec Pharmaceuticals |
Makrociklički inhibitori virusa hepatitisa c
|
|
PE20070211A1
(es)
|
2005-07-29 |
2007-05-12 |
Medivir Ab |
Compuestos macrociclicos como inhibidores del virus de hepatitis c
|
|
JP5171624B2
(ja)
|
2005-07-29 |
2013-03-27 |
テイボテク・フアーマシユーチカルズ |
C型肝炎ウイルスの大環状阻害剤
|
|
EP1915382A2
(en)
*
|
2005-08-01 |
2008-04-30 |
Phenomix Corporation |
Hepatitis c serine protease inhibitors and uses therefor
|
|
EP2402331A1
(en)
*
|
2005-08-02 |
2012-01-04 |
Vertex Pharmaceuticals Incorporated |
Inhibitors of serine proteases
|
|
SI2194043T1
(sl)
|
2005-08-19 |
2014-04-30 |
Vertex Pharmaceuticals Incorporated |
Postopki
|
|
US8399615B2
(en)
|
2005-08-19 |
2013-03-19 |
Vertex Pharmaceuticals Incorporated |
Processes and intermediates
|
|
AR055395A1
(es)
|
2005-08-26 |
2007-08-22 |
Vertex Pharma |
Compuestos inhibidores de la actividad de la serina proteasa ns3-ns4a del virus de la hepatitis c
|
|
US7964624B1
(en)
|
2005-08-26 |
2011-06-21 |
Vertex Pharmaceuticals Incorporated |
Inhibitors of serine proteases
|
|
KR20080066949A
(ko)
*
|
2005-10-11 |
2008-07-17 |
인터뮨, 인크. |
바이러스 복제 억제제
|
|
EA200801050A1
(ru)
|
2005-10-11 |
2008-12-30 |
Интермьюн, Инк. |
Соединения и способы ингибирования репликации вирусного гепатита с
|
|
US7772183B2
(en)
|
2005-10-12 |
2010-08-10 |
Bristol-Myers Squibb Company |
Hepatitis C virus inhibitors
|
|
US7741281B2
(en)
|
2005-11-03 |
2010-06-22 |
Bristol-Myers Squibb Company |
Hepatitis C virus inhibitors
|
|
MY171061A
(en)
|
2005-11-09 |
2019-09-24 |
Onyx Therapeutics Inc |
Compounds for enzyme inhibition
|
|
EP2392589A3
(en)
|
2005-11-11 |
2012-06-20 |
Vertex Pharmaceuticals Incorporated |
Hepatitis C virus variants
|
|
US7705138B2
(en)
|
2005-11-11 |
2010-04-27 |
Vertex Pharmaceuticals Incorporated |
Hepatitis C virus variants
|
|
JP5473334B2
(ja)
|
2005-12-23 |
2014-04-16 |
ジーランド ファーマ アクティーゼルスカブ |
修飾リジン模倣化合物
|
|
WO2007089618A2
(en)
*
|
2006-01-27 |
2007-08-09 |
Phenomix Corporation |
Hepatitis c serine protease inhibitors and uses therefor
|
|
TW200800265A
(en)
*
|
2006-02-09 |
2008-01-01 |
Schering Corp |
Combinations comprising HCV protease inhibitor(s) and HCV polymerase inhibitor(s), and methods of treatment related thereto
|
|
WO2007098270A2
(en)
|
2006-02-27 |
2007-08-30 |
Vertex Pharmaceuticals Incorporated |
Co-crystals comprising vx-950 and pharmaceutical compositions comprising the same
|
|
NZ571280A
(en)
*
|
2006-03-16 |
2011-10-28 |
Vertex Pharma |
Deuterated hepatitis C protease inhibitors
|
|
US7825152B2
(en)
|
2006-04-11 |
2010-11-02 |
Novartis Ag |
Organic compounds and their uses
|
|
US8017612B2
(en)
|
2006-04-18 |
2011-09-13 |
Japan Tobacco Inc. |
Piperazine compound and use thereof as a HCV polymerase inhibitor
|
|
RU2419626C2
(ru)
|
2006-05-23 |
2011-05-27 |
Айрм Ллк |
Соединения и композиции в качестве ингибиторов протеазы, активирующей каналы
|
|
AU2007261345B2
(en)
|
2006-06-19 |
2012-02-23 |
Onyx Therapeutics, Inc. |
Peptide epoxyketones for proteasome inhibition
|
|
EP2049474B1
(en)
|
2006-07-11 |
2015-11-04 |
Bristol-Myers Squibb Company |
Hepatitis c virus inhibitors
|
|
EP1886685A1
(en)
|
2006-08-11 |
2008-02-13 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods, uses and compositions for modulating replication of hcv through the farnesoid x receptor (fxr) activation or inhibition
|
|
US20080131398A1
(en)
*
|
2006-08-21 |
2008-06-05 |
United Therapeutics Corporation |
Combination therapy for treatment of viral infections
|
|
WO2008027397A2
(en)
*
|
2006-08-28 |
2008-03-06 |
Vertex Pharmaceuticals Incorporated |
Method for identifying protease inhibitors
|
|
US8343477B2
(en)
|
2006-11-01 |
2013-01-01 |
Bristol-Myers Squibb Company |
Inhibitors of hepatitis C virus
|
|
US7772180B2
(en)
|
2006-11-09 |
2010-08-10 |
Bristol-Myers Squibb Company |
Hepatitis C virus inhibitors
|
|
DK2104674T3
(da)
|
2006-11-15 |
2013-07-15 |
Vertex Pharmaceuticals Canada Inc |
Thiophenanaloger til behandling eller forebyggelse af flavivirus-infektioner
|
|
US7888464B2
(en)
|
2006-11-16 |
2011-02-15 |
Bristol-Myers Squibb Company |
Hepatitis C virus inhibitors
|
|
US8003604B2
(en)
|
2006-11-16 |
2011-08-23 |
Bristol-Myers Squibb Company |
Hepatitis C virus inhibitors
|
|
US7763584B2
(en)
|
2006-11-16 |
2010-07-27 |
Bristol-Myers Squibb Company |
Hepatitis C virus inhibitors
|
|
MX2009006056A
(es)
*
|
2006-12-07 |
2009-06-16 |
Schering Corp |
Formulacion de matriz sensible al ph.
|
|
US20080188545A1
(en)
|
2006-12-21 |
2008-08-07 |
Alimardanov Asaf R |
Synthesis of pyrrolidine compounds
|
|
AU2007339382B2
(en)
|
2006-12-22 |
2013-05-02 |
Merck Sharp & Dohme Llc |
4,5-ring annulated indole derivatives for treating or preventing of HCV and related viral infections
|
|
CN101611002A
(zh)
|
2006-12-22 |
2009-12-23 |
先灵公司 |
用于治疗或预防hcv和相关病毒感染的4,5-环化吲哚衍生物
|
|
WO2008136815A2
(en)
|
2006-12-22 |
2008-11-13 |
Schering Corporation |
5, 6-ring annulated indole derivatives and use thereof
|
|
ES2541660T3
(es)
|
2007-02-08 |
2015-07-23 |
Janssen Sciences Ireland Uc |
Inhibidores del VHC macrocíclicos sustituidos con pirimidina
|
|
EP2117537A1
(en)
*
|
2007-02-09 |
2009-11-18 |
Irm Llc |
Compounds and compositions as channel activating protease inhibitors
|
|
CN101687856A
(zh)
*
|
2007-02-27 |
2010-03-31 |
弗特克斯药品有限公司 |
共晶体和包含该共晶体的药物组合物
|
|
US8575208B2
(en)
|
2007-02-27 |
2013-11-05 |
Vertex Pharmaceuticals Incorporated |
Inhibitors of serine proteases
|
|
DK2144604T3
(da)
|
2007-02-28 |
2011-10-17 |
Conatus Pharmaceuticals Inc |
Fremgangsmåder til behandling af kronisk viral hepatitis C under anvendelse af RO 113-0830
|
|
WO2008106167A1
(en)
*
|
2007-02-28 |
2008-09-04 |
Conatus Pharmaceuticals, Inc. |
Combination therapy comprising matrix metalloproteinase inhibitors and caspase inhibitors for the treatment of liver diseases
|
|
US7964580B2
(en)
|
2007-03-30 |
2011-06-21 |
Pharmasset, Inc. |
Nucleoside phosphoramidate prodrugs
|
|
AU2008248116A1
(en)
|
2007-05-04 |
2008-11-13 |
Vertex Pharmaceuticals Incorporated |
Combination therapy for the treatment of HCV infection
|
|
UA98494C2
(uk)
|
2007-06-29 |
2012-05-25 |
Гіліад Сайєнсіз, Інк. |
Противірусні сполуки
|
|
BRPI0813733A2
(pt)
|
2007-06-29 |
2019-11-05 |
Gilead Sciences Inc |
composto com atividade inibidora de hcv, sua composição farmacêutica e seu uso.
|
|
US8143305B2
(en)
|
2007-08-29 |
2012-03-27 |
Schering Corporation |
2,3-substituted indole derivatives for treating viral infections
|
|
CN101842374A
(zh)
|
2007-08-29 |
2010-09-22 |
先灵公司 |
用于治疗病毒感染的2,3-取代的氮杂吲哚衍生物
|
|
AU2008295484B2
(en)
|
2007-08-29 |
2013-09-26 |
Merck Sharp & Dohme Llc |
Substituted indole derivatives and methods of use thereof
|
|
CN101835774B
(zh)
*
|
2007-08-30 |
2014-09-17 |
弗特克斯药品有限公司 |
共晶体和包含该共晶体的药物组合物
|
|
GB0718575D0
(en)
|
2007-09-24 |
2007-10-31 |
Angeletti P Ist Richerche Bio |
Nucleoside derivatives as inhibitors of viral polymerases
|
|
KR20170040374A
(ko)
|
2007-10-04 |
2017-04-12 |
오닉스 세라퓨틱스, 인크. |
결정형 펩티드 에폭시 케톤 프로테아제 저해제 및 아미노산 케토-에폭시드의 합성
|
|
CN102099351A
(zh)
|
2007-11-16 |
2011-06-15 |
先灵公司 |
3-杂环取代的吲哚衍生物及其使用方法
|
|
US8377928B2
(en)
|
2007-11-16 |
2013-02-19 |
Merck Sharp & Dohme Corp. |
3-aminosulfonyl substituted indole derivatives and methods of use thereof
|
|
US8202996B2
(en)
|
2007-12-21 |
2012-06-19 |
Bristol-Myers Squibb Company |
Crystalline forms of N-(tert-butoxycarbonyl)-3-methyl-L-valyl-(4R)-4-((7-chloro-4-methoxy-1-isoquinolinyl)oxy)-N- ((1R,2S)-1-((cyclopropylsulfonyl)carbamoyl)-2-vinylcyclopropyl)-L-prolinamide
|
|
NZ587133A
(en)
|
2008-02-04 |
2012-10-26 |
Idenix Pharmaceuticals Inc |
Macrocyclic serine protease inhibitor compounds for treating an HCV infection
|
|
TW200946541A
(en)
|
2008-03-27 |
2009-11-16 |
Idenix Pharmaceuticals Inc |
Solid forms of an anti-HIV phosphoindole compound
|
|
US8163921B2
(en)
|
2008-04-16 |
2012-04-24 |
Bristol-Myers Squibb Company |
Hepatitis C virus inhibitors
|
|
US8044023B2
(en)
|
2008-05-29 |
2011-10-25 |
Bristol-Myers Squibb Company |
Hepatitis C virus inhibitors
|
|
US7964560B2
(en)
|
2008-05-29 |
2011-06-21 |
Bristol-Myers Squibb Company |
Hepatitis C virus inhibitors
|
|
WO2009152200A1
(en)
|
2008-06-13 |
2009-12-17 |
Schering Corporation |
Tricyclic indole derivatives and methods of use thereof
|
|
EP2307434B1
(en)
|
2008-07-02 |
2014-02-12 |
IDENIX Pharmaceuticals, Inc. |
Compounds and pharmaceutical compositions for the treatment of viral infections
|
|
TWI409265B
(zh)
|
2008-08-20 |
2013-09-21 |
Merck Sharp & Dohme |
經取代之吡啶及嘧啶衍生物及彼等於治療病毒感染之用途
|
|
US8470834B2
(en)
|
2008-08-20 |
2013-06-25 |
Merck Sharp & Dohme Corp. |
AZO-substituted pyridine and pyrimidine derivatives and their use in treating viral infections
|
|
JP5619743B2
(ja)
|
2008-08-20 |
2014-11-05 |
メルク・シャープ・アンド・ドーム・コーポレーションMerck Sharp & Dohme Corp. |
エテニル置換ピリジンおよびピリミジン誘導体およびウイルス感染の治療におけるそれらの使用
|
|
WO2010022125A1
(en)
|
2008-08-20 |
2010-02-25 |
Schering Corporation |
Ethynyl-substituted pyridine and pyrimidine derivatives and their use in treating viral infections
|
|
US8207341B2
(en)
|
2008-09-04 |
2012-06-26 |
Bristol-Myers Squibb Company |
Process or synthesizing substituted isoquinolines
|
|
US8563505B2
(en)
|
2008-09-29 |
2013-10-22 |
Bristol-Myers Squibb Company |
Hepatitis C virus inhibitors
|
|
US8044087B2
(en)
|
2008-09-29 |
2011-10-25 |
Bristol-Myers Squibb Company |
Hepatitis C virus inhibitors
|
|
EP2341924A4
(en)
|
2008-10-02 |
2013-01-23 |
David Gladstone Inst |
METHOD FOR THE TREATMENT OF HEPATITIS C VIRUS INFECTIONS
|
|
EP3090737A1
(en)
|
2008-10-21 |
2016-11-09 |
Onyx Therapeutics, Inc. |
Combination therapy with peptide epoxyketones
|
|
BRPI0922364A2
(pt)
|
2008-12-03 |
2017-08-29 |
Presidio Pharmaceuticals Inc |
Composto, composição farmacêutica e uso de um composto
|
|
WO2010065674A1
(en)
|
2008-12-03 |
2010-06-10 |
Presidio Pharmaceuticals, Inc. |
Inhibitors of hcv ns5a
|
|
US8283310B2
(en)
|
2008-12-15 |
2012-10-09 |
Bristol-Myers Squibb Company |
Hepatitis C virus inhibitors
|
|
US8914351B2
(en)
|
2008-12-16 |
2014-12-16 |
Clinton A. Krislov |
Method and system for secure automated document registration from social media networks
|
|
US8589372B2
(en)
|
2008-12-16 |
2013-11-19 |
Clinton A. Krislov |
Method and system for automated document registration with cloud computing
|
|
UY32325A
(es)
*
|
2008-12-19 |
2010-07-30 |
Gilead Sciences Inc |
Inhibidores de ns3 proteasa del vhc
|
|
PA8855601A1
(es)
|
2008-12-23 |
2010-07-27 |
|
Forformidatos de nucleósidos
|
|
NZ617066A
(en)
|
2008-12-23 |
2015-02-27 |
Gilead Pharmasset Llc |
Nucleoside analogs
|
|
WO2010075554A1
(en)
|
2008-12-23 |
2010-07-01 |
Pharmasset, Inc. |
Synthesis of purine nucleosides
|
|
US8102720B2
(en)
*
|
2009-02-02 |
2012-01-24 |
Qualcomm Incorporated |
System and method of pulse generation
|
|
WO2010101967A2
(en)
|
2009-03-04 |
2010-09-10 |
Idenix Pharmaceuticals, Inc. |
Phosphothiophene and phosphothiazole hcv polymerase inhibitors
|
|
JP2012520884A
(ja)
|
2009-03-18 |
2012-09-10 |
ザ ボード オブ トラスティーズ オブ ザ リランド スタンフォード ジュニア ユニバーシティー |
フラビウイルス科ウイルス感染症を治療する方法および組成物
|
|
AR075899A1
(es)
|
2009-03-20 |
2011-05-04 |
Onyx Therapeutics Inc |
Tripeptidos epoxicetonas cristalinos inhibidores de proteasa
|
|
AU2010229795A1
(en)
|
2009-03-27 |
2011-10-13 |
Presidio Pharmaceuticals, Inc. |
Fused ring inhibitors of hepatitis C
|
|
EP2416765B1
(en)
|
2009-04-06 |
2016-03-30 |
PTC Therapeutics, Inc. |
Hcv inhibitor and therapeutic agent combinations
|
|
WO2010117936A1
(en)
|
2009-04-06 |
2010-10-14 |
Schering Corporation |
Combinations of a hcv inhibitor such as bicyclic pyrrole derivatives and a therapeutic agent
|
|
US8377962B2
(en)
|
2009-04-08 |
2013-02-19 |
Idenix Pharmaceuticals, Inc. |
Macrocyclic serine protease inhibitors
|
|
US20110182850A1
(en)
|
2009-04-10 |
2011-07-28 |
Trixi Brandl |
Organic compounds and their uses
|
|
US8512690B2
(en)
|
2009-04-10 |
2013-08-20 |
Novartis Ag |
Derivatised proline containing peptide compounds as protease inhibitors
|
|
US8618076B2
(en)
|
2009-05-20 |
2013-12-31 |
Gilead Pharmasset Llc |
Nucleoside phosphoramidates
|
|
TWI583692B
(zh)
|
2009-05-20 |
2017-05-21 |
基利法瑪席特有限責任公司 |
核苷磷醯胺
|
|
JP2012528195A
(ja)
|
2009-05-29 |
2012-11-12 |
メルク・シャープ・アンド・ドーム・コーポレーション |
C型肝炎などの疾患を処置するための3つの結合アリール部分で構成された抗菌性化合物
|
|
TW201117812A
(en)
|
2009-08-05 |
2011-06-01 |
Idenix Pharmaceuticals Inc |
Macrocyclic serine protease inhibitors
|
|
AU2009352688B2
(en)
|
2009-09-15 |
2014-04-17 |
Taigen Biotechnology Co., Ltd. |
HCV protease inhibitors
|
|
US8853147B2
(en)
|
2009-11-13 |
2014-10-07 |
Onyx Therapeutics, Inc. |
Use of peptide epoxyketones for metastasis suppression
|
|
WO2011063076A1
(en)
|
2009-11-19 |
2011-05-26 |
Itherx Pharmaceuticals, Inc. |
Methods of treating hepatitis c virus with oxoacetamide compounds
|
|
WO2011068715A1
(en)
|
2009-11-25 |
2011-06-09 |
Vertex Pharmaceuticals Incorporated |
5-alkynyl-thiophene-2-carboxylic acid derivatives and their use for the treatment or prevention of flavivirus infections
|
|
JP2013512246A
(ja)
|
2009-11-25 |
2013-04-11 |
メルク・シャープ・アンド・ドーム・コーポレーション |
ウイルス疾患治療に有用な縮合型三環式化合物およびその誘導体
|
|
CA2784748A1
(en)
|
2009-12-18 |
2011-06-23 |
Idenix Pharmaceuticals, Inc. |
5,5-fused arylene or heteroarylene hepatitis c virus inhibitors
|
|
EP2516449A1
(en)
|
2009-12-22 |
2012-10-31 |
Cephalon, Inc. |
Proteasome inhibitors and processes for their preparation, purification and use
|
|
US20130156731A1
(en)
|
2009-12-22 |
2013-06-20 |
Kevin X. Chen |
Fused tricyclic compounds and methods of use thereof for the treatment of viral diseas
|
|
JP2013515746A
(ja)
|
2009-12-24 |
2013-05-09 |
ヴァーテックス ファーマシューティカルズ、 インコーポレイテッド |
フラビウイルス感染症の治療又は予防のための類似体
|
|
JP5833022B2
(ja)
|
2010-01-27 |
2015-12-16 |
エービー・ファーマ・リミテッド |
C型肝炎ウィルス阻害剤としてのポリ複素環式化合物
|
|
EP2536410B1
(en)
|
2010-02-18 |
2015-09-23 |
Merck Sharp & Dohme Corp. |
Substituted pyrimidine derivatives and their use in treating viral infections
|
|
BR112012022060A2
(pt)
|
2010-03-01 |
2018-05-08 |
Onyx Therapeutics Inc |
composto para a inibição de imunoproteassoma
|
|
WO2011112516A1
(en)
|
2010-03-08 |
2011-09-15 |
Ico Therapeutics Inc. |
Treating and preventing hepatitis c virus infection using c-raf kinase antisense oligonucleotides
|
|
JP2013522202A
(ja)
|
2010-03-09 |
2013-06-13 |
メルク・シャープ・エンド・ドーム・コーポレイション |
縮合三環式シリル化合物およびウイルス疾患の治療のためのその使用方法
|
|
CA2794181A1
(en)
|
2010-03-24 |
2011-09-29 |
Vertex Pharmaceuticals Incorporated |
Analogues for the treatment or prevention of flavivirus infections
|
|
MX2012010918A
(es)
|
2010-03-24 |
2013-01-18 |
Vertex Pharma |
Analogos para el tratamiento o prevencion de infecciones por flavivirus.
|
|
TW201139438A
(en)
|
2010-03-24 |
2011-11-16 |
Vertex Pharma |
Analogues for the treatment or prevention of flavivirus infections
|
|
TW201141857A
(en)
|
2010-03-24 |
2011-12-01 |
Vertex Pharma |
Analogues for the treatment or prevention of flavivirus infections
|
|
CL2011000718A1
(es)
|
2010-03-31 |
2012-04-09 |
Gilead Pharmasset Llc |
Proceso para la preparacion de compuestos fosforados enantiomericos.
|
|
WO2011123586A1
(en)
|
2010-04-01 |
2011-10-06 |
Idenix Pharmaceuticals, Inc. |
Compounds and pharmaceutical compositions for the treatment of viral infections
|
|
WO2011136905A2
(en)
|
2010-04-07 |
2011-11-03 |
Onyx Therapeutics, Inc. |
Crystalline peptide epoxyketone immunoproteasome inhibitor
|
|
CA2800509A1
(en)
|
2010-05-24 |
2011-12-01 |
Presidio Pharmaceuticals, Inc. |
Inhibitors of hcv ns5a
|
|
WO2011156545A1
(en)
|
2010-06-09 |
2011-12-15 |
Vertex Pharmaceuticals Incorporated |
Viral dynamic model for hcv combination therapy
|
|
US20130157258A1
(en)
|
2010-06-15 |
2013-06-20 |
Vertex Pharmaceuticals Incorporated |
Hcv ns5b protease mutants
|
|
WO2012006070A1
(en)
|
2010-06-28 |
2012-01-12 |
Vertex Pharmaceuticals Incorporated |
Compounds and methods for the treatment or prevention of flavivirus infections
|
|
WO2012006060A1
(en)
|
2010-06-28 |
2012-01-12 |
Vertex Pharmaceuticals Incorporated |
Compounds and methods for the treatment or prevention of flavivirus infections
|
|
MX2012014918A
(es)
|
2010-06-28 |
2013-04-08 |
Vertex Pharma |
Compuestos y metodos para tratamiento o prevencion de infecciones por flavivirus.
|
|
US20140377223A1
(en)
|
2010-07-26 |
2014-12-25 |
Joseph A. Kozlowski |
Substituted biphenylene compounds and methods of use thereof for the treatment of viral diseases
|
|
WO2012020036A1
(en)
|
2010-08-13 |
2012-02-16 |
F. Hoffmann-La Roche Ag |
Hepatitis c virus inhibitors
|
|
MX2013001869A
(es)
|
2010-08-17 |
2013-06-28 |
Vertex Pharma |
Compuestos y metodos para el tratamiento o prevencion de infecciones virales por flaviviridae.
|
|
EP2621279B1
(en)
|
2010-09-29 |
2018-04-04 |
Merck Sharp & Dohme Corp. |
Fused tetracycle derivatives and methods of use thereof for the treatment of viral diseases
|
|
EP2624826B1
(en)
|
2010-10-08 |
2018-07-18 |
Novartis AG |
Vitamin e formulations of sulfamide ns3 inhibitors
|
|
CA2815855C
(en)
|
2010-11-01 |
2016-02-02 |
Rfs Pharma, Llc |
Novel specific hcv ns3 protease inhibitors
|
|
WO2012075140A1
(en)
|
2010-11-30 |
2012-06-07 |
Pharmasset, Inc. |
Compounds
|
|
AR085352A1
(es)
|
2011-02-10 |
2013-09-25 |
Idenix Pharmaceuticals Inc |
Inhibidores macrociclicos de serina proteasa, sus composiciones farmaceuticas y su uso para tratar infecciones por hcv
|
|
WO2012107589A1
(en)
|
2011-02-11 |
2012-08-16 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods and pharmaceutical compositions for the treatment and prevention of hcv infections
|
|
WO2012123298A1
(en)
|
2011-03-11 |
2012-09-20 |
F. Hoffmann-La Roche Ag |
Antiviral compounds
|
|
US20120252721A1
(en)
|
2011-03-31 |
2012-10-04 |
Idenix Pharmaceuticals, Inc. |
Methods for treating drug-resistant hepatitis c virus infection with a 5,5-fused arylene or heteroarylene hepatitis c virus inhibitor
|
|
EP2691409B1
(en)
|
2011-03-31 |
2018-02-21 |
Idenix Pharmaceuticals LLC. |
Compounds and pharmaceutical compositions for the treatment of viral infections
|
|
WO2012142075A1
(en)
|
2011-04-13 |
2012-10-18 |
Merck Sharp & Dohme Corp. |
2'-azido substituted nucleoside derivatives and methods of use thereof for the treatment of viral diseases
|
|
US8957203B2
(en)
|
2011-05-05 |
2015-02-17 |
Bristol-Myers Squibb Company |
Hepatitis C virus inhibitors
|
|
US10501493B2
(en)
|
2011-05-27 |
2019-12-10 |
Rqx Pharmaceuticals, Inc. |
Broad spectrum antibiotics
|
|
US8691757B2
(en)
|
2011-06-15 |
2014-04-08 |
Bristol-Myers Squibb Company |
Hepatitis C virus inhibitors
|
|
CA2857705A1
(en)
|
2011-06-16 |
2012-12-20 |
AB Pharma Ltd. |
Macrocyclic heterocyclic compounds for inhibiting hepatitis c virus and preparation and use thereof
|
|
BR112013032188A2
(pt)
|
2011-06-23 |
2016-12-20 |
Digna Biotech Sl |
composição, produto e método para tratar pacientes com hepatite c crônica
|
|
WO2012175581A1
(en)
|
2011-06-24 |
2012-12-27 |
F. Hoffmann-La Roche Ag |
Antiviral compounds
|
|
CN102807607B
(zh)
*
|
2011-07-22 |
2013-10-23 |
爱博新药研发(上海)有限公司 |
抑制丙肝病毒的稠环杂环类化合物、其中间体及其应用
|
|
TW201313697A
(zh)
|
2011-07-26 |
2013-04-01 |
Vertex Pharma |
製備噻吩化合物之方法
|
|
WO2013016499A1
(en)
|
2011-07-26 |
2013-01-31 |
Vertex Pharmaceuticals Incorporated |
Methods for preparation of thiophene compounds
|
|
WO2013033901A1
(en)
|
2011-09-08 |
2013-03-14 |
Merck Sharp & Dohme Corp. |
Heterocyclic-substituted benzofuran derivatives and methods of use thereof for the treatment of viral diseases
|
|
WO2013033899A1
(en)
|
2011-09-08 |
2013-03-14 |
Merck Sharp & Dohme Corp. |
Substituted benzofuran compounds and methods of use thereof for the treatment of viral diseases
|
|
WO2013033900A1
(en)
|
2011-09-08 |
2013-03-14 |
Merck Sharp & Dohme Corp. |
Tetracyclic heterocycle compounds and methods of use thereof for the treatment of viral diseases
|
|
CN103906759A
(zh)
|
2011-09-12 |
2014-07-02 |
埃迪尼克斯医药公司 |
用于治疗病毒感染的化合物和药物组合物
|
|
US9403863B2
(en)
|
2011-09-12 |
2016-08-02 |
Idenix Pharmaceuticals Llc |
Substituted carbonyloxymethylphosphoramidate compounds and pharmaceutical compositions for the treatment of viral infections
|
|
WO2013039876A1
(en)
|
2011-09-14 |
2013-03-21 |
Merck Sharp & Dohme Corp. |
Silyl-containing heterocyclic compounds and methods of use thereof for the treatment of viral diseases
|
|
HK1199454A1
(en)
|
2011-10-10 |
2015-07-03 |
F. Hoffmann-La Roche Ag |
Antiviral compounds
|
|
WO2013056046A1
(en)
|
2011-10-14 |
2013-04-18 |
Idenix Pharmaceuticals, Inc. |
Substituted 3',5'-cyclic phosphates of purine nucleotide compounds and pharmaceutical compositions for the treatment of viral infections
|
|
US20130123276A1
(en)
|
2011-11-14 |
2013-05-16 |
Sven Ruf |
Use of telaprevir and related compounds in atherosclerosis, heart failure, renal diseases, liver diseases or inflammatory diseases
|
|
US8889159B2
(en)
|
2011-11-29 |
2014-11-18 |
Gilead Pharmasset Llc |
Compositions and methods for treating hepatitis C virus
|
|
CN104185420B
(zh)
|
2011-11-30 |
2017-06-09 |
埃默里大学 |
用于治疗或预防逆转录病毒和其它病毒感染的抗病毒jak抑制剂
|
|
WO2013086133A1
(en)
|
2011-12-06 |
2013-06-13 |
The Board Of Trustees Of The Leland Stanford Junior University |
Methods and compositions for treating viral diseases
|
|
CN103987723B
(zh)
|
2011-12-16 |
2017-03-01 |
弗·哈夫曼-拉罗切有限公司 |
Hcv ns5a 的抑制剂
|
|
PT2794628T
(pt)
|
2011-12-20 |
2017-07-05 |
Riboscience Llc |
Derivados nucleosídicos 4¿-azido-3¿-fluoro substituídos como inibidores de replicação de arn de vhc
|
|
CA2856179C
(en)
|
2011-12-20 |
2017-02-28 |
F. Hoffmann-La Roche Ag |
2',4'-difluoro-2'-methyl substituted nucleoside derivatives as inhibitors of hcv rna replication
|
|
US8809354B2
(en)
|
2011-12-31 |
2014-08-19 |
Sheikh Riazuddin |
3-amino-2-(4-nitrophenyl)-4-(3H)-quinazolinone or derivatives thereof for treating or preventing antiviral infections
|
|
WO2013106689A1
(en)
|
2012-01-12 |
2013-07-18 |
Ref Pharma, Llc. |
Hcv ns3 protease inhibitors
|
|
WO2013133927A1
(en)
|
2012-02-13 |
2013-09-12 |
Idenix Pharmaceuticals, Inc. |
Pharmaceutical compositions of 2'-c-methyl-guanosine, 5'-[2-[(3-hydroxy-2,2-dimethyl-1-oxopropyl)thio]ethyl n-(phenylmethyl)phosphoramidate]
|
|
HK1205736A1
(en)
*
|
2012-02-16 |
2015-12-24 |
阿奇克斯制药公司 |
Linear peptide antibiotics
|
|
CN104185624B
(zh)
*
|
2012-02-24 |
2016-10-12 |
弗·哈夫曼-拉罗切有限公司 |
抗病毒化合物
|
|
EP2827876A4
(en)
|
2012-03-22 |
2015-10-28 |
Alios Biopharma Inc |
PHARMACEUTICAL COMBINATIONS WITH A THIONUCLEOTIDE ANALOG
|
|
EP2852605B1
(en)
|
2012-05-22 |
2018-01-31 |
Idenix Pharmaceuticals LLC |
3',5'-cyclic phosphate prodrugs for hcv infection
|
|
US9109001B2
(en)
|
2012-05-22 |
2015-08-18 |
Idenix Pharmaceuticals, Inc. |
3′,5′-cyclic phosphoramidate prodrugs for HCV infection
|
|
MX355708B
(es)
|
2012-05-22 |
2018-04-27 |
Idenix Pharmaceuticals Llc |
Compuestos de d-aminoacidos para enfermedades del higado.
|
|
US20140010783A1
(en)
|
2012-07-06 |
2014-01-09 |
Hoffmann-La Roche Inc. |
Antiviral compounds
|
|
US9309283B2
(en)
|
2012-07-09 |
2016-04-12 |
Onyx Therapeutics, Inc. |
Prodrugs of peptide epoxy ketone protease inhibitors
|
|
WO2014053533A1
(en)
|
2012-10-05 |
2014-04-10 |
Sanofi |
Use of substituted 3-heteroaroylamino-propionic acid derivatives as pharmaceuticals for prevention/treatment of atrial fibrillation
|
|
EA030189B8
(ru)
|
2012-10-08 |
2018-10-31 |
Иденикс Фармасьютикалз Ллс |
Аналоги 2'-хлоронуклеозидов для инфекции вгс
|
|
US20140112886A1
(en)
|
2012-10-19 |
2014-04-24 |
Idenix Pharmaceuticals, Inc. |
Dinucleotide compounds for hcv infection
|
|
KR20150074051A
(ko)
|
2012-10-19 |
2015-07-01 |
브리스톨-마이어스 스큅 컴퍼니 |
C형 간염 바이러스 억제제
|
|
EP2909222B1
(en)
|
2012-10-22 |
2021-05-26 |
Idenix Pharmaceuticals LLC |
2',4'-bridged nucleosides for hcv infection
|
|
US10260089B2
(en)
|
2012-10-29 |
2019-04-16 |
The Research Foundation Of The State University Of New York |
Compositions and methods for recognition of RNA using triple helical peptide nucleic acids
|
|
WO2014071007A1
(en)
|
2012-11-02 |
2014-05-08 |
Bristol-Myers Squibb Company |
Hepatitis c virus inhibitors
|
|
US9643999B2
(en)
|
2012-11-02 |
2017-05-09 |
Bristol-Myers Squibb Company |
Hepatitis C virus inhibitors
|
|
WO2014070964A1
(en)
|
2012-11-02 |
2014-05-08 |
Bristol-Myers Squibb Company |
Hepatitis c virus inhibitors
|
|
US9409943B2
(en)
|
2012-11-05 |
2016-08-09 |
Bristol-Myers Squibb Company |
Hepatitis C virus inhibitors
|
|
EP2920195A1
(en)
|
2012-11-14 |
2015-09-23 |
IDENIX Pharmaceuticals, Inc. |
D-alanine ester of rp-nucleoside analog
|
|
EP2938624A1
(en)
|
2012-11-14 |
2015-11-04 |
IDENIX Pharmaceuticals, Inc. |
D-alanine ester of sp-nucleoside analog
|
|
EP2935304A1
(en)
|
2012-12-19 |
2015-10-28 |
IDENIX Pharmaceuticals, Inc. |
4'-fluoro nucleosides for the treatment of hcv
|
|
BR112015017414A2
(pt)
|
2013-01-23 |
2017-07-11 |
Hoffmann La Roche |
derivados de triazol antivirais
|
|
WO2014134251A1
(en)
|
2013-02-28 |
2014-09-04 |
Vertex Pharmaceuticals Incorporated |
Pharmaceutical compositions
|
|
EP2970358B1
(en)
|
2013-03-04 |
2021-06-30 |
Idenix Pharmaceuticals LLC |
3'-deoxy nucleosides for the treatment of hcv
|
|
US9339541B2
(en)
|
2013-03-04 |
2016-05-17 |
Merck Sharp & Dohme Corp. |
Thiophosphate nucleosides for the treatment of HCV
|
|
RU2015136256A
(ru)
|
2013-03-05 |
2017-04-10 |
Ф. Хоффманн-Ля Рош Аг |
Противовирусные соединения
|
|
JP6342922B2
(ja)
|
2013-03-07 |
2018-06-13 |
ブリストル−マイヤーズ スクイブ カンパニーBristol−Myers Squibb Company |
C型肝炎ウイルス阻害剤
|
|
WO2014165542A1
(en)
|
2013-04-01 |
2014-10-09 |
Idenix Pharmaceuticals, Inc. |
2',4'-fluoro nucleosides for the treatment of hcv
|
|
MX2015015781A
(es)
|
2013-05-16 |
2016-06-02 |
Riboscience Llc |
Derivados de nucleósido 4'-azido, 3'-deoxi-3'-fluoro sustituido.
|
|
MX2015015782A
(es)
|
2013-05-16 |
2016-06-02 |
Riboscience Llc |
Derivados de nucleosido 4'-fluoro-2'-metil sustituido.
|
|
US20180200280A1
(en)
|
2013-05-16 |
2018-07-19 |
Riboscience Llc |
4'-Fluoro-2'-Methyl Substituted Nucleoside Derivatives as Inhibitors of HCV RNA Replication
|
|
US10005779B2
(en)
|
2013-06-05 |
2018-06-26 |
Idenix Pharmaceuticals Llc |
1′,4′-thio nucleosides for the treatment of HCV
|
|
WO2015017713A1
(en)
|
2013-08-01 |
2015-02-05 |
Idenix Pharmaceuticals, Inc. |
D-amino acid phosphoramidate pronucleotides of halogeno pyrimidine compounds for liver disease
|
|
US20160194358A1
(en)
*
|
2013-08-14 |
2016-07-07 |
Rqx Pharmaceuticals, Inc. |
Linear peptide antibiotcs
|
|
SG11201600919UA
(en)
|
2013-08-27 |
2016-03-30 |
Gilead Pharmasset Llc |
Combination formulation of two antiviral compounds
|
|
EP3046924A1
(en)
|
2013-09-20 |
2016-07-27 |
IDENIX Pharmaceuticals, Inc. |
Hepatitis c virus inhibitors
|
|
WO2015061683A1
(en)
|
2013-10-25 |
2015-04-30 |
Idenix Pharmaceuticals, Inc. |
D-amino acid phosphoramidate and d-alanine thiophosphoramidate pronucleotides of nucleoside compounds useful for the treatment of hcv
|
|
WO2015065817A1
(en)
|
2013-10-30 |
2015-05-07 |
Merck Sharp & Dohme Corp. |
Pseudopolymorphs of an hcv ns5a inhibitor and uses thereof
|
|
WO2015066370A1
(en)
|
2013-11-01 |
2015-05-07 |
Idenix Pharmaceuticals, Inc. |
D-alanine phosphoramidate pronucleotides of 2'-methyl 2'-fluoro guanosine nucleoside compounds for the treatment of hcv
|
|
US20170198005A1
(en)
|
2013-11-27 |
2017-07-13 |
Idenix Pharmaceuticals Llc |
2'-dichloro and 2'-fluoro-2'-chloro nucleoside analogues for hcv infection
|
|
WO2015095419A1
(en)
|
2013-12-18 |
2015-06-25 |
Idenix Pharmaceuticals, Inc. |
4'-or nucleosides for the treatment of hcv
|
|
EP2899207A1
(en)
|
2014-01-28 |
2015-07-29 |
Amikana.Biologics |
New method for testing HCV protease inhibition
|
|
EP3114122A1
(en)
|
2014-03-05 |
2017-01-11 |
Idenix Pharmaceuticals LLC |
Solid forms of a flaviviridae virus inhibitor compound and salts thereof
|
|
WO2015134561A1
(en)
|
2014-03-05 |
2015-09-11 |
Idenix Pharmaceuticals, Inc. |
Pharmaceutical compositions comprising a 5,5-fused heteroarylene flaviviridae inhibitor and their use for treating or preventing flaviviridae infection
|
|
EP3113763A1
(en)
|
2014-03-05 |
2017-01-11 |
Idenix Pharmaceuticals LLC |
Solid prodrug forms of 2'-chloro-2'-methyl uridine for hcv
|
|
EP3131914B1
(en)
|
2014-04-16 |
2023-05-10 |
Idenix Pharmaceuticals LLC |
3'-substituted methyl or alkynyl nucleosides for the treatment of hcv
|
|
CA3005551A1
(en)
|
2015-11-20 |
2017-05-26 |
Rqx Pharmaceuticals, Inc. |
Macrocyclic broad spectrum antibiotics
|
|
US10526315B2
(en)
|
2016-06-21 |
2020-01-07 |
Orion Ophthalmology LLC |
Carbocyclic prolinamide derivatives
|
|
DK3472149T3
(da)
|
2016-06-21 |
2023-11-27 |
Orion Ophthalmology LLC |
Heterocykliske prolinamidderivater
|
|
EP3472130B1
(en)
|
2016-06-21 |
2022-02-16 |
Orion Ophthalmology LLC |
Aliphatic prolinamide derivatives
|
|
WO2018036942A1
(en)
*
|
2016-08-23 |
2018-03-01 |
F. Hoffmann-La Roche Ag |
New difluoroketamide derivatives as htra1 inhibitors
|
|
JP6989864B2
(ja)
|
2017-05-05 |
2022-02-03 |
ジーランド ファーマ,アー/エス |
ギャップ結合細胞間コミュニケーションモジュレータ及び糖尿病性眼疾患の治療のためのそれらの使用
|
|
GB2563396B
(en)
*
|
2017-06-12 |
2020-09-23 |
Ustav Organicke Chemie A Biochemie Av Cr V V I |
Inhibitors of Rhomboid Intramembrane Proteases
|
|
US10682369B2
(en)
|
2017-09-21 |
2020-06-16 |
Riboscience Llc |
4′-fluoro-2′-methyl substituted nucleoside derivatives as inhibitors of HCV RNA replication
|
|
CN113167802B
(zh)
|
2018-12-04 |
2025-02-07 |
百时美施贵宝公司 |
通过多同位素体反应监测使用样品内校准曲线的分析方法
|
|
IL288294B
(en)
|
2019-05-28 |
2022-09-01 |
Hoffmann La Roche |
Macrocyclic broad spectrum antibiotics
|