EA030246B1 - Полимерные соединения-иммуномодулирующие средства - Google Patents

Полимерные соединения-иммуномодулирующие средства Download PDF

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Publication number
EA030246B1
EA030246B1 EA201171480A EA201171480A EA030246B1 EA 030246 B1 EA030246 B1 EA 030246B1 EA 201171480 A EA201171480 A EA 201171480A EA 201171480 A EA201171480 A EA 201171480A EA 030246 B1 EA030246 B1 EA 030246B1
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EA
Eurasian Patent Office
Prior art keywords
polymer
solution
alkyl
compound according
poly
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EA201171480A
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English (en)
Russian (ru)
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EA201171480A1 (ru
Inventor
Чарльз Зепп
Грэйсон Б. Липфорд
Юнь Гао
Ллойд Джонстон
Фынь-ни Фу
Марк Дж. Киган
Сэм Болдуин
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Селекта Байосайенсиз, Инк.
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Publication of EA201171480A1 publication Critical patent/EA201171480A1/ru
Publication of EA030246B1 publication Critical patent/EA030246B1/ru

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K39/39—Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • C07D473/26—Heterocyclic compounds containing purine ring systems with an oxygen, sulphur, or nitrogen atom directly attached in position 2 or 6, but not in both
    • C07D473/32—Nitrogen atom
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    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/437—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a five-membered ring having nitrogen as a ring hetero atom, e.g. indolizine, beta-carboline
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    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
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