EA013740B1 - Новые пиридиноновые производные и их применение в качестве позитивных аллостерических модуляторов mglur2-рецепторов - Google Patents

Новые пиридиноновые производные и их применение в качестве позитивных аллостерических модуляторов mglur2-рецепторов Download PDF

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Publication number
EA013740B1
EA013740B1 EA200700617A EA200700617A EA013740B1 EA 013740 B1 EA013740 B1 EA 013740B1 EA 200700617 A EA200700617 A EA 200700617A EA 200700617 A EA200700617 A EA 200700617A EA 013740 B1 EA013740 B1 EA 013740B1
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EA
Eurasian Patent Office
Prior art keywords
pyridin
chlorobenzyl
methoxyphenyl
alkyl
fluorobenzyl
Prior art date
Application number
EA200700617A
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English (en)
Russian (ru)
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EA200700617A1 (ru
Inventor
Хассан Жюльен Имогай
Хосе Мария Сид-Нуньес
Гийом Альбер Жак Дювей
Кристелль Мартин Болеа
Вантеа Нем
Терри Патрик Финн
Эмманюэль Кристиан Ле Пуль
Жан-Филипп Франсуа Кристиан Роше
Роберт Иоганнес Лютьенс
Original Assignee
Орто-Макнейл-Янссен Фармасьютикалз, Инк.
Аддекс Фарма Са
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Publication of EA200700617A1 publication Critical patent/EA200700617A1/ru
Publication of EA013740B1 publication Critical patent/EA013740B1/ru

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    • C07D211/68—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D211/72—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, directly attached to ring carbon atoms
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    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
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EA200700617A 2004-09-17 2005-09-16 Новые пиридиноновые производные и их применение в качестве позитивных аллостерических модуляторов mglur2-рецепторов EA013740B1 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB0420722A GB0420722D0 (en) 2004-09-17 2004-09-17 Novel allosteric modulators
PCT/EP2005/054636 WO2006030032A1 (en) 2004-09-17 2005-09-16 Novel pyridinone derivatives and their use as positive allosteric modulators of mglur2-receptors

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EA200700617A1 EA200700617A1 (ru) 2007-10-26
EA013740B1 true EA013740B1 (ru) 2010-06-30

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US8399493B2 (en) 2013-03-19
ES2527418T3 (es) 2015-01-23
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TW200633982A (en) 2006-10-01
CA2581144C (en) 2014-04-01
WO2006030032A1 (en) 2006-03-23
UA98098C2 (ru) 2012-04-25
EP1799646A1 (en) 2007-06-27
CA2581144A1 (en) 2006-03-23
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JP2008513414A (ja) 2008-05-01
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CN101061098B (zh) 2012-05-23
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JP2013047254A (ja) 2013-03-07
JP5723850B2 (ja) 2015-05-27
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SG155938A1 (en) 2009-10-29
AU2005284098A1 (en) 2006-03-23
JP5179873B2 (ja) 2013-04-10
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KR20070085262A (ko) 2007-08-27
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