DZ312A1 - Interferons et procédé pour leur préparation. - Google Patents

Interferons et procédé pour leur préparation.

Info

Publication number
DZ312A1
DZ312A1 DZ816241A DZ816241A DZ312A1 DZ 312 A1 DZ312 A1 DZ 312A1 DZ 816241 A DZ816241 A DZ 816241A DZ 816241 A DZ816241 A DZ 816241A DZ 312 A1 DZ312 A1 DZ 312A1
Authority
DZ
Algeria
Prior art keywords
interferes
preparation
Prior art date
Application number
DZ816241A
Other languages
English (en)
French (fr)
Inventor
David Van Norman Goeddel
Sidney Pestka
Original Assignee
Genentech Inc
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=27496622&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DZ312(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from US06/256,204 external-priority patent/US6610830B1/en
Application filed by Genentech Inc, Hoffmann La Roche filed Critical Genentech Inc
Application granted granted Critical
Publication of DZ312A1 publication Critical patent/DZ312A1/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/555—Interferons [IFN]
    • C07K14/56—IFN-alpha
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/70—Vectors or expression systems specially adapted for E. coli
    • C12N15/71—Expression systems using regulatory sequences derived from the trp-operon
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00—Preparation of peptides or proteins
    • C12P21/02—Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Toxicology (AREA)
  • Medicinal Chemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
DZ816241A 1980-07-01 1981-06-29 Interferons et procédé pour leur préparation. DZ312A1 (fr)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US16498680A 1980-07-01 1980-07-01
US18490980A 1980-09-08 1980-09-08
US20557880A 1980-11-10 1980-11-10
US06/256,204 US6610830B1 (en) 1980-07-01 1981-04-21 Microbial production of mature human leukocyte interferons

Publications (1)

Publication Number Publication Date
DZ312A1 true DZ312A1 (fr) 2004-09-13

Family

ID=27496622

Family Applications (1)

Application Number Title Priority Date Filing Date
DZ816241A DZ312A1 (fr) 1980-07-01 1981-06-29 Interferons et procédé pour leur préparation.

Country Status (36)

Country Link
EP (2) EP0043980B1 (es)
AR (1) AR242833A1 (es)
AT (3) ATE79901T1 (es)
AU (1) AU552004B2 (es)
BG (1) BG42189A3 (es)
BR (1) BR8104189A (es)
CH (2) CH657141A5 (es)
CS (1) CS273152B2 (es)
DD (3) DD202307A5 (es)
DE (3) DE3125706C2 (es)
DK (1) DK173543B1 (es)
DZ (1) DZ312A1 (es)
ES (1) ES503528A0 (es)
FI (1) FI82712C (es)
FR (1) FR2486098B1 (es)
GB (1) GB2079291B (es)
GE (1) GEP19960519B (es)
GR (1) GR75714B (es)
HK (1) HK49285A (es)
HU (1) HU196457B (es)
IE (1) IE49255B1 (es)
IT (1) IT1137272B (es)
KE (1) KE3534A (es)
LU (1) LU83461A1 (es)
MC (1) MC1396A1 (es)
MY (1) MY8700711A (es)
NL (1) NL8103151A (es)
NO (1) NO159392C (es)
NZ (1) NZ197572A (es)
PH (1) PH18036A (es)
PL (3) PL148260B1 (es)
PT (1) PT73289B (es)
RO (1) RO87590A (es)
SE (2) SE8104093L (es)
SU (1) SU1414319A3 (es)
YU (1) YU47700B (es)

Families Citing this family (50)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ZA811368B (en) * 1980-03-24 1982-04-28 Genentech Inc Bacterial polypedtide expression employing tryptophan promoter-operator
IL62552A0 (en) 1980-04-03 1981-06-29 Biogen Nv Dna sequences,recombinant dna molecules and processes for producing human fibroblast interferon-like polypeptides
DE3176011D1 (en) * 1980-06-12 1987-04-23 Japan Found Cancer Plasmid
DK489481A (da) * 1980-11-10 1982-05-11 Searle & Co Plasmidvektor og frmgangsmaade til fremstilling deraf
NZ199722A (en) * 1981-02-25 1985-12-13 Genentech Inc Dna transfer vector for expression of exogenous polypeptide in yeast;transformed yeast strain
EP0085693A1 (en) * 1981-08-14 1983-08-17 A/S Alfred Benzon Subjects relating to human inteferon-alpha subtype proteins and corresponding antibodies
JPS58110548A (ja) * 1981-12-24 1983-07-01 Asahi Chem Ind Co Ltd 新規な生理活性ペプチド
US4975276A (en) * 1982-01-15 1990-12-04 Cetus Corporation Interferon-alpha 54
US5098703A (en) * 1982-01-15 1992-03-24 Cetus Corporation Interferon-alpha 76
US4973479A (en) * 1982-01-15 1990-11-27 Cetus Corporation Interferon-α61
US4775622A (en) * 1982-03-08 1988-10-04 Genentech, Inc. Expression, processing and secretion of heterologous protein by yeast
US6432677B1 (en) 1982-03-08 2002-08-13 Genentech, Inc. Non-human animal interferons
US5827694A (en) * 1982-03-08 1998-10-27 Genentech, Inc. DNA encoding non-human animal interferons, vectors and hosts therefor, and recombinant production of IFN polypeptides
IE54592B1 (en) * 1982-03-08 1989-12-06 Genentech Inc Anumal interferons, processes involved in their production, compositions containing them, dna sequences coding therefor and espression vehicles containing such sequences and cells transformed thereby
EP0088994B1 (en) * 1982-03-15 1991-06-19 Schering Corporation Hybrid dna, binding composition prepared thereby and processes therefor
US4695543A (en) * 1982-03-23 1987-09-22 Bristol-Myers Company Alpha Interferon GX-1
US4748233A (en) * 1982-03-23 1988-05-31 Bristol-Myers Company Alpha-interferon Gx-1
CA1210714A (en) * 1982-03-23 1986-09-02 Alan Sloma .alpha.-INTERFERON GX-1
US6936694B1 (en) 1982-05-06 2005-08-30 Intermune, Inc. Manufacture and expression of large structural genes
US5831023A (en) * 1982-11-01 1998-11-03 Genentech, Inc. Recombinant animal interferon polypeptides
GB2150573B (en) * 1983-02-24 1987-11-11 Inst Organicheskogo Sinteza Ak Leukocytic human interferon n and method to obtain it in bacterial cells
EP0165942A1 (en) * 1983-12-23 1986-01-02 Monash University PRODUCTION OF HUMAN INTERFERON-$g(a)
SU1364343A1 (ru) * 1984-07-13 1988-01-07 Всесоюзный научно-исследовательский институт генетики и селекции промышленных микроорганизмов Способ получени человеческого лейкоцитарного интерферона альфа-2
IL76360A0 (en) 1984-09-26 1986-01-31 Takeda Chemical Industries Ltd Mutual separation of proteins
WO1986002068A1 (en) * 1984-09-26 1986-04-10 Takeda Chemical Industries, Ltd. Mutual separation of proteins
US5196323A (en) * 1985-04-27 1993-03-23 Boehringer Ingelheim International Gmbh Process for preparing and purifying alpha-interferon
DE3515336C2 (de) * 1985-04-27 1994-01-20 Boehringer Ingelheim Int Verfahren zur Herstellung und Reinigung von â-Interferon
JP2514950B2 (ja) * 1986-03-10 1996-07-10 エフ・ホフマン―ラ ロシユ アーゲー 化学修飾蛋白質，その製造法および中間体
JPS6463395A (en) * 1987-05-04 1989-03-09 Oncogen Oncostatin m and novel composition having antitumor activity
CA1309044C (en) * 1987-11-09 1992-10-20 Toshiya Takano Method of producing foreign gene products
GB8813032D0 (en) * 1988-06-02 1988-07-06 Boehringer Ingelheim Int Antiviral pharmaceutical composition
WO1991003251A1 (en) * 1989-09-08 1991-03-21 California Institute Of Biological Research Cr2 ligand compositions and methods for modulating immune cell functions
DE3932311A1 (de) * 1989-09-28 1991-04-11 Boehringer Ingelheim Int Verfahren zur reinigung von beta-interferon
EP0741577B1 (en) * 1994-03-07 2002-11-06 IMPERIAL COLLEGE OF SCIENCE, TECHNOLOGY & MEDICINE The use of interferon subtype alpha 8 in the preparation of medicaments to treat viral infections of the liver
DE69522492T2 (de) * 1994-04-09 2002-05-23 Hoffmann La Roche Verfahren zur Herstellung von Alpha-Interferon
GB9609932D0 (en) * 1996-05-13 1996-07-17 Hoffmann La Roche Use of IL-12 and IFN alpha for the treatment of infectious diseases
US20030190307A1 (en) 1996-12-24 2003-10-09 Biogen, Inc. Stable liquid interferon formulations
ZA9811070B (en) 1997-12-08 2000-07-03 Genentech Inc Type I interferons.
US6299869B1 (en) 1997-12-08 2001-10-09 Genentech, Inc. Human interferon-epsilon: a type I interferon
CN102161984B (zh) 1998-08-06 2016-06-01 山景药品公司 分离四聚体尿酸氧化酶的方法
US6783965B1 (en) 2000-02-10 2004-08-31 Mountain View Pharmaceuticals, Inc. Aggregate-free urate oxidase for preparation of non-immunogenic polymer conjugates
US6268178B1 (en) 1999-05-25 2001-07-31 Phage Biotechnology Corp. Phage-dependent super-production of biologically active protein and peptides
AU2002228886B2 (en) * 2000-11-03 2007-08-30 Pestka Biomedical Laboratories, Inc. Interferons, uses and compositions related thereto
FR2822845B1 (fr) 2001-03-30 2003-12-12 Genodyssee Nouveaux polynucleotides comportant des polymorphismes de type snp fonctionnels dans la sequence nucleotidique du gene ifn-alpha-21 ainsi que de nouveaux polypeptides codes par ces polynucleotides et leurs utilisations therapeutiques
FR2823220B1 (fr) 2001-04-04 2003-12-12 Genodyssee Nouveaux polynucleotides et polypeptides de l'erythropoietine (epo)
FR2825716B1 (fr) 2001-06-11 2004-09-24 Genodyssee Nouveaux polynucleotides et polypeptides de l'ifn alpha 7
HUE052976T2 (hu) 2005-04-11 2021-06-28 Horizon Pharma Rheumatology Llc Urát-oxidáz variáns formái és azok alkalmazása
EP2245044A2 (en) * 2008-01-18 2010-11-03 F. Hoffmann-La Roche AG Purification of non-glycosylated proteins
MX347903B (es) 2009-06-25 2017-05-18 Crealta Pharmaceuticals Llc Metodos y equipos para predecir el riesgo de reaccion a la infusion y perdida de respuesta mediada por anticuerpos al supervisar el acido urico en suero durante una terapia con uricasa conjugada con peg.
WO2018087345A1 (en) 2016-11-14 2018-05-17 F. Hoffmann-La Roche Ag COMBINATION THERAPY OF AN HBsAg INHIBITOR, A NUCLEOS(T)IDE ANALOGUE AND AN INTERFERON

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IN150740B (es) * 1978-11-24 1982-12-04 Hoffmann La Roche
FI77877C (fi) * 1979-04-20 1989-05-10 Technobiotic Ltd Foerfarande foer framstaellning och rening av human le-formig interferonprotein.
GR73557B (es) * 1980-01-08 1984-03-15 Biogen Inc
DE3005897A1 (de) * 1980-02-16 1981-09-03 Hoechst Ag, 6000 Frankfurt Genprodukt eines hoeheren organismus aus einem dieses gen enhtaltenden mikroorganismus
DE3176011D1 (en) * 1980-06-12 1987-04-23 Japan Found Cancer Plasmid
ES8302778A1 (es) * 1980-11-10 1983-02-01 Genentech Inc Un procedimiento para producir un polipeptido antiviral.
FI64813C (fi) * 1980-12-31 1984-01-10 Ilkka Antero Palva Foerfarande foer producering av ett utvalt aeggviteaemne och vid foerfarandet anvaenda rekombinantplasmidvektorer
EP0062971B1 (en) * 1981-03-27 1990-03-07 Imperial Chemical Industries Plc Genetically modified microorganisms

Also Published As

Publication number Publication date
DE3125706C2 (de) 1995-05-24
PT73289A (en) 1981-07-01
PL231940A1 (en) 1983-07-18
EP0043980A3 (en) 1982-09-15
DD210304A5 (de) 1984-06-06
DK291081A (da) 1982-01-02
AT380272B (de) 1986-05-12
ES8207514A1 (es) 1982-10-01
CS273152B2 (en) 1991-03-12
DE3177288D1 (de) 1992-10-01
NO812247L (no) 1982-01-04
EP0043980A2 (en) 1982-01-20
AU552004B2 (en) 1986-05-22
AU7246281A (en) 1982-01-07
GB2079291A (en) 1982-01-20
MY8700711A (en) 1987-12-31
DE3176448D1 (en) 1987-10-22
GEP19960519B (en) 1996-07-02
PL148261B1 (en) 1989-09-30
PL148260B1 (en) 1989-09-30
DD210305A5 (de) 1984-06-06
KE3534A (en) 1985-06-07
FI82712B (fi) 1990-12-31
EP0211148A1 (en) 1987-02-25
IT1137272B (it) 1986-09-03
YU162281A (en) 1984-02-29
NZ197572A (en) 1985-07-31
PT73289B (en) 1983-05-11
CH657141A5 (de) 1986-08-15
HK49285A (en) 1985-07-05
FR2486098A1 (fr) 1982-01-08
IE49255B1 (en) 1985-09-04
LU83461A1 (de) 1983-04-06
DD202307A5 (de) 1983-09-07
DE3177288T3 (de) 2000-03-16
NL8103151A (nl) 1982-02-01
GB2079291B (en) 1984-06-13
BG42189A3 (en) 1987-10-15
BR8104189A (pt) 1982-03-16
IT8122682A0 (it) 1981-07-01
PH18036A (en) 1985-03-06
SU1414319A3 (ru) 1988-07-30
MC1396A1 (fr) 1982-04-27
CH651308A5 (de) 1985-09-13
CS503781A2 (en) 1990-07-12
GR75714B (es) 1984-08-02
EP0211148B2 (en) 1999-11-24
SE465223B (sv) 1991-08-12
DE3125706A1 (de) 1982-04-15
RO87590A (ro) 1986-07-30
AR242833A1 (es) 1993-05-31
NO159392B (no) 1988-09-12
ATE79901T1 (de) 1992-09-15
ATA290981A (de) 1985-09-15
ES503528A0 (es) 1982-10-01
FR2486098B1 (fr) 1985-12-27
EP0211148B1 (en) 1992-08-26
PL148276B1 (en) 1989-09-30
HU196457B (en) 1988-11-28
DK173543B1 (da) 2001-02-05
YU47700B (sh) 1996-01-08
EP0043980B1 (en) 1987-09-16
FI82712C (fi) 1991-04-10
IE811463L (en) 1982-01-01
ATE29727T1 (de) 1987-10-15
DE3177288T2 (de) 1992-12-10
NO159392C (no) 1988-12-21
SE8104093L (sv) 1982-01-02
SE465223C5 (sv) 1998-02-10
FI812067L (fi) 1982-01-02

Similar Documents

Publication Publication Date Title
DZ312A1 (fr) Interferons et procédé pour leur préparation.
OA06914A (fr) Procédé de préparation d'iminodiacides substitués.
BE854009A (fr) Acrylamide-amidons et procede pour leur preparation
MC1389A1 (fr) Derives d'imidazole et procede pour leur preparation
BE877595A (fr) Nouveaux prostenoides et procede pour leur preparation
BE862578A (fr) Electrocatalyseurs et procede pour leur preparation
NO811959L (no) Apparat for raffinering av smeltet metall.
BE893707R (fr) Azabicyclohexanes et procede de leur preparation
BE889049A (fr) Nouvelles quinoxaline-2-yl-ethenylcetones et leur procede de preparation
BE864739A (fr) Polypeptides et procede pour leur preparation
OA06794A (fr) 2-Nitroimidazoles, et procédés pour leur préparation.
OA07341A (fr) Nouveaux oximéthers, procédé pour leur préparation, agents contenant les nouveaux oximéthers et leur application.
BE888740A (fr) Elements de refroidissement de four et leur procede d'obtention
BE862800A (fr) Nouvelles dithienylalkylamines et procede pour leur preparation
BE851681A (fr) 2,9-dioxatricyclo-4,3,03,7- decanes et procede pour leur preparation
BE873464A (fr) Analogues de beta h-endorphine et procede pour leur preparation
OA06314A (fr) Benzimidazoles et procédés pour leur préparation.
MC1549A1 (fr) Anthracycline-glycosides,procede pour leur preparation et medicaments les contenant
NO156613C (no) Apparat for raffinering av smeltet metall.
MA18466A1 (fr) Fongicides et procede pour leur preparation
BE889339A (fr) 6-hydrazono-pyrido(2,1-b)quinazoline-11-ones et procede pour leur preparation
BE869407A (fr) 2-cyclopropyl-chromones substituees et procede pour leur preparation
BE857981R (fr) 2,9-dioxatricyclo (4,3,1,0 3,7) decanes et procede pour leur preparation
OA06845A (fr) Interférons et procédé pour leur préparation.
FR2533917B1 (fr) Derives 15-cycloaliphatiques de 13,14-bisdeshydro-carboprostacyclines et procede pour leur preparation