DK173034B1 - Vandopløselige S-isomerer og racemiske blandinger af camptothecinanaloger, fremgangsmåde til fremstilling deraf samt midler - Google Patents

Vandopløselige S-isomerer og racemiske blandinger af camptothecinanaloger, fremgangsmåde til fremstilling deraf samt midler Download PDF

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Publication number
DK173034B1
DK173034B1 DK198806636A DK663688A DK173034B1 DK 173034 B1 DK173034 B1 DK 173034B1 DK 198806636 A DK198806636 A DK 198806636A DK 663688 A DK663688 A DK 663688A DK 173034 B1 DK173034 B1 DK 173034B1
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Denmark
Prior art keywords
hydroxy
compound
tumor
isomer
formula
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DK198806636A
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Danish (da)
English (en)
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DK663688D0 (da
DK663688A (da
Inventor
Jeffrey Charles Boehm
Sidney Michael Hecht
Kenneth George Holden
Randall Keith Johnson
William Dennis Kingsbury
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Smithkline Beecham Corp
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/12—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains three hetero rings
    • C07D491/14—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/22—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains four or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
DK198806636A 1987-12-01 1988-11-28 Vandopløselige S-isomerer og racemiske blandinger af camptothecinanaloger, fremgangsmåde til fremstilling deraf samt midler DK173034B1 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US12714887A 1987-12-01 1987-12-01
US12714887 1987-12-01

Publications (3)

Publication Number Publication Date
DK663688D0 DK663688D0 (da) 1988-11-28
DK663688A DK663688A (da) 1989-06-02
DK173034B1 true DK173034B1 (da) 1999-11-29

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ID=22428545

Family Applications (1)

Application Number Title Priority Date Filing Date
DK198806636A DK173034B1 (da) 1987-12-01 1988-11-28 Vandopløselige S-isomerer og racemiske blandinger af camptothecinanaloger, fremgangsmåde til fremstilling deraf samt midler

Country Status (25)

Country Link
US (1) US5004758A (fr)
EP (1) EP0321122B1 (fr)
JP (1) JPH0633268B2 (fr)
KR (1) KR930009357B1 (fr)
CN (3) CN1027265C (fr)
AT (1) ATE143368T1 (fr)
AU (1) AU612735B2 (fr)
CA (1) CA1308102C (fr)
CY (1) CY2017A (fr)
DE (2) DE19775017I2 (fr)
DK (1) DK173034B1 (fr)
ES (1) ES2094721T3 (fr)
FI (1) FI89923C (fr)
GR (1) GR3021990T3 (fr)
HK (1) HK81097A (fr)
IE (1) IE74873B1 (fr)
IL (1) IL88517A (fr)
LU (2) LU90026I2 (fr)
MX (1) MX9203744A (fr)
NL (1) NL970017I2 (fr)
NO (2) NO170487C (fr)
NZ (1) NZ227124A (fr)
PT (1) PT89111B (fr)
SG (1) SG66254A1 (fr)
ZA (1) ZA888938B (fr)

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US5004758A (en) 1991-04-02
AU612735B2 (en) 1991-07-18
EP0321122A3 (fr) 1990-12-27
SG66254A1 (en) 1999-07-20
DE3855575T2 (de) 1997-03-20
ZA888938B (en) 1990-03-28
NO1998003I1 (no) 1998-01-15
FI885569A (fi) 1989-06-02
FI89923B (fi) 1993-08-31
IE74873B1 (en) 1997-08-13
CN1035380C (zh) 1997-07-09
NO170487B (no) 1992-07-13
NO885352L (no) 1989-06-02
MX9203744A (es) 1992-09-01
KR930009357B1 (ko) 1993-09-28
JPH0633268B2 (ja) 1994-05-02
NO885352D0 (no) 1988-11-30
LU90053I2 (fr) 1997-07-01
CY2017A (en) 1998-02-20
NL970017I2 (nl) 1997-09-01
CA1308102C (fr) 1992-09-29
PT89111B (pt) 1994-01-31
FI885569A0 (fi) 1988-11-30
CN1034724A (zh) 1989-08-16
JPH01186893A (ja) 1989-07-26
FI89923C (fi) 1993-12-10
DK663688D0 (da) 1988-11-28
CN1083817A (zh) 1994-03-16
CN1087637A (zh) 1994-06-08
KR890009934A (ko) 1989-08-05
NZ227124A (en) 1991-12-23
DE19775017I2 (de) 2002-11-07
NO170487C (no) 1992-10-21
DE3855575D1 (de) 1996-10-31
DK663688A (da) 1989-06-02
IE883576L (en) 1989-06-01
GR3021990T3 (en) 1997-03-31
PT89111A (pt) 1989-12-29
CN1037574C (zh) 1998-03-04
IL88517A0 (en) 1989-06-30
IL88517A (en) 1994-10-07
EP0321122A2 (fr) 1989-06-21
NL970017I1 (nl) 1997-06-02
HK81097A (en) 1997-06-20
ATE143368T1 (de) 1996-10-15
ES2094721T3 (es) 1997-02-01
EP0321122B1 (fr) 1996-09-25
AU2639488A (en) 1989-06-01
CN1027265C (zh) 1995-01-04
LU90026I2 (fr) 1997-04-22

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