DK153289A - Selektiv forstaerkning af maal-polynucleotidsekvenser - Google Patents

Selektiv forstaerkning af maal-polynucleotidsekvenser

Info

Publication number
DK153289A
DK153289A DK153289A DK153289A DK153289A DK 153289 A DK153289 A DK 153289A DK 153289 A DK153289 A DK 153289A DK 153289 A DK153289 A DK 153289A DK 153289 A DK153289 A DK 153289A
Authority
DK
Denmark
Prior art keywords
copies
sequence
target
target polynucleotide
polynucleotide sequences
Prior art date
Application number
DK153289A
Other languages
Danish (da)
English (en)
Other versions
DK153289D0 (da
Inventor
Lawrence James Burg
Philippe Jacques Pouletty
John Charles Boothroyd
Original Assignee
Univ Leland Stanford Junior
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=22157643&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK153289(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Univ Leland Stanford Junior filed Critical Univ Leland Stanford Junior
Publication of DK153289D0 publication Critical patent/DK153289D0/da
Publication of DK153289A publication Critical patent/DK153289A/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/5308Immunoassay; Biospecific binding assay; Materials therefor for analytes not provided for elsewhere, e.g. nucleic acids, uric acid, worms, mites
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/67General methods for enhancing the expression
    • C12N15/69Increasing the copy number of the vector
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6844Nucleic acid amplification reactions
    • C12Q1/6865Promoter-based amplification, e.g. nucleic acid sequence amplification [NASBA], self-sustained sequence replication [3SR] or transcription-based amplification system [TAS]
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6888Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms
    • C12Q1/6893Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms for protozoa

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Analytical Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Immunology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Physics & Mathematics (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Biophysics (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Urology & Nephrology (AREA)
  • General Physics & Mathematics (AREA)
  • Cell Biology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Plant Pathology (AREA)
  • Pathology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Saccharide Compounds (AREA)
  • Multicomponent Fibers (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Traffic Control Systems (AREA)
DK153289A 1987-07-31 1989-03-30 Selektiv forstaerkning af maal-polynucleotidsekvenser DK153289A (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US8047987A 1987-07-31 1987-07-31
PCT/US1988/002601 WO1989001050A1 (en) 1987-07-31 1988-07-29 Selective amplification of target polynucleotide sequences

Publications (2)

Publication Number Publication Date
DK153289D0 DK153289D0 (da) 1989-03-30
DK153289A true DK153289A (da) 1989-03-30

Family

ID=22157643

Family Applications (1)

Application Number Title Priority Date Filing Date
DK153289A DK153289A (da) 1987-07-31 1989-03-30 Selektiv forstaerkning af maal-polynucleotidsekvenser

Country Status (13)

Country Link
US (2) US5437990A (pt)
EP (2) EP0682120B1 (pt)
JP (1) JP2774121B2 (pt)
KR (1) KR960013577B1 (pt)
AT (1) ATE135053T1 (pt)
CA (1) CA1340843C (pt)
DE (2) DE3856455T2 (pt)
DK (1) DK153289A (pt)
ES (1) ES2086298T3 (pt)
FI (1) FI891436A0 (pt)
IE (1) IE72468B1 (pt)
PT (1) PT88168B (pt)
WO (1) WO1989001050A1 (pt)

Families Citing this family (433)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5714380A (en) 1986-10-23 1998-02-03 Amoco Corporation Closed vessel for isolating target molecules and for performing amplification
US6090591A (en) * 1987-07-31 2000-07-18 The Board Of Trustees Of The Leland Stanford Junior University Selective amplification of target polynucleotide sequences
JP2774121B2 (ja) * 1987-07-31 1998-07-09 ザ ボード オブ トラスティーズ オブ ザ リーランド スタンフォード ジュニア ユニバーシティ 標的ポリヌクレオチド配列の選択的増幅
JP2846018B2 (ja) * 1988-01-21 1999-01-13 ジェネンテク,インコーポレイテッド 核酸配列の増幅および検出
JP2650159B2 (ja) * 1988-02-24 1997-09-03 アクゾ・ノベル・エヌ・ベー 核酸増幅方法
CA1340807C (en) * 1988-02-24 1999-11-02 Lawrence T. Malek Nucleic acid amplification process
US5130238A (en) * 1988-06-24 1992-07-14 Cangene Corporation Enhanced nucleic acid amplification process
KR0148265B1 (ko) * 1988-12-16 1998-10-15 에프.지이.엠 헤르만스 자가-지속 서열 복제 시스템
US5112734A (en) * 1989-05-26 1992-05-12 Gene-Trak Systems Target-dependent synthesis of an artificial gene for the synthesis of a replicatable rna
DE69034265D1 (de) 1989-06-02 2009-04-09 Pasteur Institut Nukleotid-Sequenzen von HIV-1, HIV-2 und SIV Retrovirusgenomen, ihre Verwendung zur Amplifizierung von pol-Sequenzen dieser Retroviren und zur In Vitro Diagnostik von diesen Viren verursachten Infektionen
FR2650839A1 (fr) * 1989-08-08 1991-02-15 Oris Ind Cie Procede de detection en phase homogene liquide de sequences specifiques d'acides nucleiques et ses applications
EP0478630B1 (fr) * 1989-06-12 1993-09-01 Cis Bio International Procede de detection de sequences specifiques d'acides nucleiques et ses applications
US7009041B1 (en) 1989-07-11 2006-03-07 Gen-Probe Incorporated Oligonucleotides for nucleic acid amplification and for the detection of Mycobacterium tuberculosis
ES2091225T3 (es) * 1989-07-11 1996-11-01 Gen Probe Inc Metodos para la amplificacion de las secuencias de acidos nucleicos.
CA2020958C (en) * 1989-07-11 2005-01-11 Daniel L. Kacian Nucleic acid sequence amplification methods
US6589734B1 (en) 1989-07-11 2003-07-08 Gen-Probe Incorporated Detection of HIV
US5766849A (en) * 1989-07-11 1998-06-16 Gen-Probe Incorporated Methods of amplifying nucleic acids using promoter-containing primer sequence
WO1991004340A1 (en) * 1989-09-20 1991-04-04 Cambridge Biotech Corporation In vitro, isothermal nucleic acid amplification
US5545522A (en) * 1989-09-22 1996-08-13 Van Gelder; Russell N. Process for amplifying a target polynucleotide sequence using a single primer-promoter complex
US7049102B1 (en) 1989-09-22 2006-05-23 Board Of Trustees Of Leland Stanford University Multi-gene expression profile
US5215899A (en) * 1989-11-09 1993-06-01 Miles Inc. Nucleic acid amplification employing ligatable hairpin probe and transcription
NO904633L (no) * 1989-11-09 1991-05-10 Molecular Diagnostics Inc Amplifikasjon av nukleinsyrer ved transkriberbar haarnaalsprobe.
IE65771B1 (en) * 1990-01-25 1995-11-15 Zeneca Ltd Amplification of nucleotide sequences using vectorette units
GB9002625D0 (en) * 1990-02-06 1990-04-04 Univ Singapore Human leukocyte antigen typing
US5194370A (en) * 1990-05-16 1993-03-16 Life Technologies, Inc. Promoter ligation activated transcription amplification of nucleic acid sequences
US5707796A (en) * 1990-06-11 1998-01-13 Nexstar Pharmaceuticals, Inc. Method for selecting nucleic acids on the basis of structure
FR2664290B1 (fr) * 1990-07-05 1993-01-29 Centre Nat Rech Scient Sondes genetiques specifiques de toxoplasma gondii, et leur utilisation pour la detection in vitro de toxoplasma gondii et pour le typage des souches toxoplasmiques.
US5162209A (en) * 1991-01-18 1992-11-10 Beth Israel Hospital Association Synthesis of full-length, double-stranded dna from a single-stranded linear dna template
WO1992020820A1 (en) * 1991-05-15 1992-11-26 Vanderbilt University Method to determine metastatic potential of tumor cells
DE4129653A1 (de) * 1991-09-06 1993-03-11 Boehringer Mannheim Gmbh Verfahren zum nachweis aehnlicher nukleinsaeuren
WO1993005184A1 (en) * 1991-09-10 1993-03-18 Love Jack D Dna/rna target and signal amplification
DE69214243T2 (de) * 1991-09-23 1997-02-06 Pfizer Verfahren für die Detektion von spezifische mRNS und DNS in Zellen
DE4213029A1 (de) * 1991-09-26 1993-04-01 Boehringer Mannheim Gmbh Verfahren zur spezifischen vervielfaeltigung von nukleins aeuresequenzen
DE4132133A1 (de) * 1991-09-26 1993-04-01 Boehringer Mannheim Gmbh Verfahren zur spezifischen herstellung von ribonukleinsaeuren
US5981179A (en) * 1991-11-14 1999-11-09 Digene Diagnostics, Inc. Continuous amplification reaction
US6100099A (en) * 1994-09-06 2000-08-08 Abbott Laboratories Test strip having a diagonal array of capture spots
CA2135073C (en) * 1992-05-06 2002-11-19 Daniel L. Kacian Nucleic acid sequence amplification method, composition and kit
US5843640A (en) * 1992-06-19 1998-12-01 Northwestern University Method of simultaneously detecting amplified nucleic acid sequences and cellular antigens in cells
KR100189229B1 (ko) * 1993-07-23 1999-06-01 다니엘 엘. 캐시앙, 헨리 엘. 노르호프 핵산 증폭을 강화하는 방법
FR2708288B1 (fr) 1993-07-26 1995-09-01 Bio Merieux Procédé d'amplification d'acides nucléiques par transcription utilisant le déplacement, réactifs et nécessaire pour la mise en Óoeuvre de ce procédé.
EP0682121B1 (en) * 1993-12-01 2002-08-28 Toyo Boseki Kabushiki Kaisha Method of amplifying and detecting target nucleic acid sequence by using thermostable enzymes
KR100230718B1 (ko) * 1994-03-16 1999-11-15 다니엘 엘. 캐시앙, 헨리 엘. 노르호프 등온 가닥 변위 핵산 증폭법
FR2724934B1 (fr) * 1994-09-26 1997-01-24 Bio Merieux Oligonucleotide chimere et son utilisation dans l'obtention de transcrits d'un acide nucleique
US5514551A (en) * 1994-10-14 1996-05-07 Gen-Probe Incorporated Compositions for the detection of Chlamydia trachomatis
US5932450A (en) * 1995-06-07 1999-08-03 Gen-Probe Incorporated Enzymatic synthesis of oligonucleotides using digestible templates
US5652126A (en) * 1995-06-07 1997-07-29 Gen-Probe Incorporated Use of restriction endonuclease sequences for cleaving phosphorothioate oligonucleotides
US5916777A (en) * 1995-06-07 1999-06-29 Gen-Probe Incorporated Enzymatic synthesis of oligonucleotides using 3'-ribonucleotide primers
US5739311A (en) * 1995-06-07 1998-04-14 Gen-Probe Incorporated Enzymatic synthesis of phosphorothioate oligonucleotides using restriction endonucleases
US6436638B1 (en) 1996-05-09 2002-08-20 Metropolitan Water District Of Southern California Cryptosporidium detection method
US5770368A (en) * 1996-05-09 1998-06-23 Metropolitan Water District Of Southern California Cryptosporidium detection method
WO1997044488A2 (en) 1996-05-22 1997-11-27 Gen-Probe Incorporated Compositions and methods for the detection of mycobacterium kansasii
JPH1028585A (ja) * 1996-07-16 1998-02-03 Toyobo Co Ltd 耐熱性リボヌクレアーゼhを用いる核酸増幅法
ATE339514T1 (de) 1996-07-16 2006-10-15 Gen Probe Inc Verfahren zum nachweis und amplifikation von nukleinsäuresequenzen unter verbrauch von modifizierten oligonukleotiden mit erhöhter zielschmelztemperatur (tm)
US7070925B1 (en) 1996-07-16 2006-07-04 Gen-Probe Incorporated Method for determining the presence of an RNA analyte in a sample using a modified oligonucleotide probe
US5838267A (en) * 1996-10-09 1998-11-17 Ericsson, Inc. Method and apparatus for encoding and decoding digital information
US6025133A (en) * 1996-12-30 2000-02-15 Gen-Probe Incorporated Promoter-sequestered oligonucleoside and method of use
JP3968810B2 (ja) * 1997-01-24 2007-08-29 東ソー株式会社 核酸配列分析方法
AU6846698A (en) 1997-04-01 1998-10-22 Glaxo Group Limited Method of nucleic acid amplification
US6429007B1 (en) * 1997-05-02 2002-08-06 BIOMéRIEUX, INC. Nucleic acid amplification reaction station for disposable test devices
IL124275A (en) * 1997-05-02 2002-03-10 Bio Merieux Vitek Inc A method to produce sequences of nucleic acids
US6534273B2 (en) 1997-05-02 2003-03-18 Gen-Probe Incorporated Two-step hybridization and capture of a polynucleotide
US5989499A (en) * 1997-05-02 1999-11-23 Biomerieux, Inc. Dual chamber disposable reaction vessel for amplification reactions
ES2271994T3 (es) 1997-05-02 2007-04-16 Gen-Probe Incorporated Hibridacion en dos pasos y captura de un polinucleotido.
US5786182A (en) * 1997-05-02 1998-07-28 Biomerieux Vitek, Inc. Dual chamber disposable reaction vessel for amplification reactions, reaction processing station therefor, and methods of use
US6558901B1 (en) * 1997-05-02 2003-05-06 Biomerieux Vitek Nucleic acid assays
US6410275B1 (en) 1997-05-02 2002-06-25 Biomerieux, Inc. Disposable test devices for performing nucleic acid amplification reactions
US5932451A (en) * 1997-11-19 1999-08-03 Incyte Pharmaceuticals, Inc. Method for unbiased mRNA amplification
ATE363339T1 (de) 1998-05-01 2007-06-15 Gen Probe Inc Rührvorrichtung für den fluiden inhalt eines behälters
AR021833A1 (es) 1998-09-30 2002-08-07 Applied Research Systems Metodos de amplificacion y secuenciacion de acido nucleico
US6153411A (en) 1998-10-30 2000-11-28 American Water Works Company, Inc. Methods and kits for detection of Cryptosporidium parvum using immunomagnetic separation and amplification
US6582906B1 (en) 1999-04-05 2003-06-24 Affymetrix, Inc. Proportional amplification of nucleic acids
US6132997A (en) * 1999-05-28 2000-10-17 Agilent Technologies Method for linear mRNA amplification
US6864050B2 (en) * 1999-07-30 2005-03-08 Affymetrix, Inc. Single-phase amplification of nucleic acids
AT410218B (de) 1999-08-20 2003-03-25 Baxter Ag Verfahren zur herstellung eines qualitätsgesicherten pools biologischer proben
US6692918B2 (en) * 1999-09-13 2004-02-17 Nugen Technologies, Inc. Methods and compositions for linear isothermal amplification of polynucleotide sequences
DK1218542T3 (da) 1999-09-13 2004-08-02 Nugen Technologies Inc Fremgangsmåder og sammensætninger til lineær isotermisk amplifikation af polynukleotidsekvenser
WO2001038572A1 (fr) * 1999-11-19 2001-05-31 Takara Bio Inc. Methode d'amplification d'acides nucleiques
US6794138B1 (en) 1999-12-16 2004-09-21 Affymetrix, Inc. Methods of small sample amplification
US6582938B1 (en) 2001-05-11 2003-06-24 Affymetrix, Inc. Amplification of nucleic acids
US6489114B2 (en) 1999-12-17 2002-12-03 Bio Merieux Process for labeling a ribonucleic acid, and labeled RNA fragments which are obtained thereby
US6902891B2 (en) 1999-12-17 2005-06-07 Bio Merieux Process for labeling a nucleic acid
DE60141087D1 (de) 2000-06-26 2010-03-04 Nugen Technologies Inc Methoden und zusammensetzungen zur auf transkription basierenden vervielfältigung von nukleinsäuren
US7846733B2 (en) 2000-06-26 2010-12-07 Nugen Technologies, Inc. Methods and compositions for transcription-based nucleic acid amplification
DE60040874D1 (de) 2000-09-01 2009-01-02 Gen Probe Inc Amplifizierung von hiv-1 sequenzen zur detektion ven einhergehen
EP1399585B1 (en) 2000-10-23 2008-02-20 Gen-Probe Incorporated Compositions and methods for detecting human immunodeficiency virus 2 (hiv-2)
AR031640A1 (es) 2000-12-08 2003-09-24 Applied Research Systems Amplificacion isotermica de acidos nucleicos en un soporte solido
EP1427847B1 (en) 2000-12-13 2010-07-28 Nugen Technologies, Inc. Methods and compositions for generation of multiple copies of nucleic acid sequences and methods of detection thereof
US6794141B2 (en) 2000-12-22 2004-09-21 Arcturus Bioscience, Inc. Nucleic acid amplification
US6867021B2 (en) * 2001-02-20 2005-03-15 Board Of Trustees Of Michigan State University Multiplex RT-PCR/PCR for simultaneous detection of bovine coronavirus, bovine rotavirus, Cryptosporidium parvum, and Escherichia coli
JP2005508135A (ja) * 2001-03-09 2005-03-31 ニューゲン テクノロジーズ, インコーポレイテッド Rna配列の増幅のための方法および組成物
MXPA02012739A (es) 2001-03-09 2004-04-20 Nugen Technologies Inc Metodos y composiciones para amplificacion de secuencias de arn.
US8137911B2 (en) * 2001-05-22 2012-03-20 Cellscript, Inc. Preparation and use of single-stranded transcription substrates for synthesis of transcription products corresponding to target sequences
US7838270B2 (en) * 2001-05-22 2010-11-23 The University Of Chicago Target-dependent transcription using deletion mutants of N4 RNA polymerase
US6872529B2 (en) * 2001-07-25 2005-03-29 Affymetrix, Inc. Complexity management of genomic DNA
US7297778B2 (en) 2001-07-25 2007-11-20 Affymetrix, Inc. Complexity management of genomic DNA
TWI335938B (en) * 2001-08-15 2011-01-11 Rna replication and amplification
US7045319B2 (en) 2001-10-30 2006-05-16 Ribomed Biotechnologies, Inc. Molecular detection systems utilizing reiterative oligonucleotide synthesis
KR100446621B1 (ko) * 2001-12-18 2004-09-07 삼성전자주식회사 다중 중합효소 연쇄반응에 의한 mody3유전자의 증폭을 위한 프라이머 세트
JP2005513457A (ja) * 2001-12-19 2005-05-12 アフィメトリックス インコーポレイテッド アレイプレートおよびアレイプレートを構築するための方法
AU2003220249A1 (en) * 2002-03-15 2003-09-29 Arcturus Bioscience, Inc. Improved nucleic acid amplification
US7498171B2 (en) 2002-04-12 2009-03-03 Anthrogenesis Corporation Modulation of stem and progenitor cell differentiation, assays, and uses thereof
KR20050008720A (ko) 2002-05-17 2005-01-21 벡톤 디킨슨 앤드 컴퍼니 표적 핵산 서열의 분리, 증폭 및 검출을 위한 자동화 시스템
AU2003253651C1 (en) 2002-06-14 2010-06-03 Gen-Probe Incorporated Compositions and methods for detecting hepatitis B virus
KR100442832B1 (ko) * 2002-07-10 2004-08-02 삼성전자주식회사 다중 중합효소 연쇄반응에 의한 mody2 유전자의증폭을 위한 프라이머 세트
US20040009483A1 (en) * 2002-07-12 2004-01-15 Ilsley Diane D. Method of linear mRNA amplification using total RNA
US7504215B2 (en) 2002-07-12 2009-03-17 Affymetrix, Inc. Nucleic acid labeling methods
US20050003369A1 (en) * 2002-10-10 2005-01-06 Affymetrix, Inc. Method for depleting specific nucleic acids from a mixture
EP2977470B1 (en) 2002-10-16 2018-01-03 Gen-Probe Incorporated Compositions and methods for detecting west nile virus
CA2504234C (en) 2002-10-29 2011-09-13 Riken Process for amplifying nucleic acids
US20040101844A1 (en) * 2002-11-21 2004-05-27 Amorese Douglas A. Methods and compositions for producing linearly amplified amounts of (+) strand RNA
AU2003294440A1 (en) * 2002-11-21 2004-06-18 Epicentre Technologies Methods for using riboprimers for strand displacement replication of target sequences
US6852494B2 (en) 2003-01-10 2005-02-08 Linden Technologies, Inc. Nucleic acid amplification
WO2004083806A2 (en) 2003-01-22 2004-09-30 University Of South Florida Autonomous genosensor apparatus and methods for use
WO2004092418A2 (en) 2003-04-14 2004-10-28 Nugen Technologies, Inc. Global amplification using a randomly primed composite primer
US20040248102A1 (en) 2003-06-03 2004-12-09 Diane Ilsley-Tyree Methods and compositions for performing template dependent nucleic acid primer extension reactions that produce a reduced complexity product
EP2327796A1 (en) 2003-06-10 2011-06-01 The Trustees Of Boston University Detection methods for disorders of the lung
US8173785B2 (en) 2003-11-26 2012-05-08 Advandx, Inc. Peptide nucleic acid probes for analysis of certain Staphylococcus species
DE602004028862D1 (de) 2003-12-19 2010-10-07 Gen Probe Inc Der nukleinsäuren von hiv-1 und hiv-2
US20050147975A1 (en) * 2003-12-24 2005-07-07 Schembri Carol T. Methods and compositions for amplification of genomic DNA
JP3897805B2 (ja) 2003-12-25 2007-03-28 独立行政法人理化学研究所 核酸の増幅法およびこれを利用した変異核酸の検出法
WO2005071117A2 (en) 2004-01-23 2005-08-04 Biomerieux, Inc. Primer and probe design for efficient amplification and detection of hcv 3′ non-translating region
US20050191682A1 (en) 2004-02-17 2005-09-01 Affymetrix, Inc. Methods for fragmenting DNA
WO2005083121A1 (en) * 2004-02-27 2005-09-09 Seegene, Inc. Method for amplifying members of a gene family
CN102680440A (zh) 2004-06-07 2012-09-19 先锋生物科技股份有限公司 用于微流体器件的光学透镜系统和方法
AU2005262317B2 (en) 2004-07-13 2009-07-16 Gen-Probe Incorporated Compositions and methods for detection of hepatitis A virus nucleic acid
JPWO2006006722A1 (ja) 2004-07-13 2008-05-01 武田薬品工業株式会社 細胞機能の調節方法
CN1993481A (zh) * 2004-07-30 2007-07-04 东曹株式会社 用于测定不均一核核糖核蛋白B1(hnRNP B1)mRNA的方法
CA2957197C (en) 2004-08-27 2017-12-12 Gen-Probe Incorporated Single-primer nucleic acid amplification methods
US7713697B2 (en) * 2004-08-27 2010-05-11 Gen-Probe Incorporated Methods and kits for amplifying DNA
EP1647600A3 (en) 2004-09-17 2006-06-28 Affymetrix, Inc. (A US Entity) Methods for identifying biological samples by addition of nucleic acid bar-code tags
DK2975139T3 (da) 2004-09-30 2019-12-09 Gen Probe Inc Assay til at detektere og kvantificere hiv-1
US20060073511A1 (en) 2004-10-05 2006-04-06 Affymetrix, Inc. Methods for amplifying and analyzing nucleic acids
EP1652580A1 (en) 2004-10-29 2006-05-03 Affymetrix, Inc. High throughput microarray, package assembly and methods of manufacturing arrays
US7682782B2 (en) 2004-10-29 2010-03-23 Affymetrix, Inc. System, method, and product for multiple wavelength detection using single source excitation
EP1809772B1 (en) * 2004-11-09 2013-06-05 Gen-Probe Incorporated Compositions and methods for detecting group a streptococci
EP1841879A4 (en) 2005-01-25 2009-05-27 Population Genetics Technologi ISOTHERMAL DNA AMPLIFICATION
JP5897780B2 (ja) 2005-01-28 2016-03-30 デューク ユニバーシティ プリント回路基板上の液滴操作装置及び方法
DE602006018586D1 (de) * 2005-02-07 2011-01-13 Gen Probe Inc Zusammensetzungen und verfahren zum nachweis von streptokokken der gruppe b
WO2006089154A1 (en) * 2005-02-18 2006-08-24 Gen-Probe Incorporated Sample preparation method incorporating an alkaline shock
CN101128604A (zh) * 2005-02-28 2008-02-20 生物探索公司 用于进行涉及核酸分子的直接酶反应的方法
US20060223071A1 (en) * 2005-04-01 2006-10-05 Wisniewski Michele E Methods, compositions, and kits for detecting nucleic acids in a single vessel
US20100035244A1 (en) 2005-04-14 2010-02-11 The Trustees Of Boston University Diagnostic for lung disorders using class prediction
CA2605015C (en) 2005-05-06 2013-09-10 Gen-Probe Incorporated Compositions and assays to detect influenza virus a and b nucleic acids
AU2006246975B2 (en) 2005-05-17 2011-08-11 Ozgene Pty Ltd Sequential cloning system
US7550264B2 (en) 2005-06-10 2009-06-23 Datascope Investment Corporation Methods and kits for sense RNA synthesis
GB0514910D0 (en) 2005-07-20 2005-08-24 Solexa Ltd Method for sequencing a polynucleotide template
GB0514935D0 (en) 2005-07-20 2005-08-24 Solexa Ltd Methods for sequencing a polynucleotide template
US20070054301A1 (en) * 2005-09-06 2007-03-08 Gen-Probe Incorporated Methods, compositions and kits for isothermal amplification of nucleic acids
WO2007030759A2 (en) 2005-09-07 2007-03-15 Nugen Technologies, Inc. Improved nucleic acid amplification procedure
EP2400037A1 (en) 2005-10-17 2011-12-28 Gen-Probe Incorporated Compositions and methods to detect legionella pneumophila nucleic acid
ATE504044T1 (de) 2005-11-14 2011-04-15 Gen Probe Inc Parametrisches kalibrationsverfahren
WO2008018904A2 (en) 2006-01-18 2008-02-14 Argos Therapeutics, Inc. Systems and methods for processing samples in a closed container, and related devices
US7368265B2 (en) * 2006-01-23 2008-05-06 Compass Genetics, Llc Selective genome amplification
SG169356A1 (en) 2006-02-08 2011-03-30 Illumina Cambridge Ltd Method for sequencing a polynucleotide template
US20110143344A1 (en) * 2006-03-01 2011-06-16 The Washington University Genetic polymorphisms and substance dependence
US20090176878A1 (en) * 2007-10-05 2009-07-09 Washington University In St. Louis Genetic polymorphisms and substance dependence
EP2605018A1 (en) 2006-03-09 2013-06-19 The Trustees of the Boston University Diagnostic and prognostic methods for lung disorders using gene expression profiles from nose epithelial cells
JP5154548B2 (ja) * 2006-05-12 2013-02-27 ジェン−プローブ・インコーポレーテッド 腸球菌核酸を検出するための組成物及び方法
JP2009539404A (ja) 2006-06-12 2009-11-19 オンコメチローム サイエンシズ エス.エイ. 大腸癌の早期検出および予後のためのメチル化マーカー
US9051601B2 (en) 2006-08-01 2015-06-09 Gen-Probe Incorporated Methods of nonspecific target capture of nucleic acids
EP2057465A4 (en) 2006-08-09 2010-04-21 Homestead Clinical Corp SPECIFIC ORGAN PROTEINS AND METHODS OF USE
US7754429B2 (en) 2006-10-06 2010-07-13 Illumina Cambridge Limited Method for pair-wise sequencing a plurity of target polynucleotides
US9845494B2 (en) 2006-10-18 2017-12-19 Affymetrix, Inc. Enzymatic methods for genotyping on arrays
US20090275632A1 (en) * 2006-10-27 2009-11-05 Oncomethylome Sciences Sa Methods of diagnosis and treatment
CA2668235A1 (en) 2006-11-02 2008-06-05 Yale University Assessment of oocyte competence
US8293684B2 (en) * 2006-11-29 2012-10-23 Exiqon Locked nucleic acid reagents for labelling nucleic acids
US8198027B2 (en) 2006-12-21 2012-06-12 Gen-Probe Incorporated Methods and compositions for nucleic acid amplification
GB0701253D0 (en) 2007-01-23 2007-02-28 Diagnostics For The Real World Nucleic acid amplification and testing
WO2008093098A2 (en) 2007-02-02 2008-08-07 Illumina Cambridge Limited Methods for indexing samples and sequencing multiple nucleotide templates
US8183359B2 (en) * 2007-03-01 2012-05-22 Gen-Probe Incorporated Kits for amplifying DNA
US8039214B2 (en) * 2007-06-29 2011-10-18 Cellscript, Inc. Synthesis of tagged nucleic acids
JP2010532986A (ja) * 2007-07-09 2010-10-21 マイクロセンス メドテック リミテッド 改良された微生物の検出
US8420315B2 (en) 2007-08-06 2013-04-16 Orion Genomics Llc Single nucleotide polymorphisms and combinations of novel and known polymorphisms for determining the allele-specific expression of the IGF2 gene
CA2639416C (en) 2007-09-11 2019-12-31 F. Hoffmann-La Roche Ag Diagnostic test for susceptibility to b-raf kinase inhibitors
JP5697448B2 (ja) 2007-09-17 2015-04-08 エムディーエックスヘルス エスエー 膀胱癌の検出のための新規なマーカー
WO2009037438A1 (en) 2007-09-17 2009-03-26 Oncomethylome Sciences Sa Improved detection of mage-a expression
WO2009059317A2 (en) 2007-11-01 2009-05-07 University Of Iowa Research Foundation Predicting amd with snps within or near c2, factor b, plekha1, htra1, prelp, or loc387715
EP2235214B1 (en) 2007-12-26 2014-07-09 Gen Probe Inc COMPOSITIONS AND METHODS FOR DETECTING CANDIDA ALBICANS NUCLEIC ACID
WO2009089598A2 (en) * 2008-01-18 2009-07-23 Katholieke Universiteit Leuven Msmb-gene methylation based diagnosis, staging and prognosis of prostate cancer
US20090203531A1 (en) 2008-02-12 2009-08-13 Nurith Kurn Method for Archiving and Clonal Expansion
EP2677041A3 (en) 2008-02-19 2014-04-09 MDxHealth SA Detection and prognosis of lung cancer
WO2011025477A1 (en) 2009-08-25 2011-03-03 Illumina, Inc. Methods for selecting and amplifying polynucleotides
US12060554B2 (en) 2008-03-10 2024-08-13 Illumina, Inc. Method for selecting and amplifying polynucleotides
EP2626435B1 (en) 2008-03-21 2016-06-01 MDxHealth S.A. Detection and prognosis of cervical cancer
US7846666B2 (en) 2008-03-21 2010-12-07 Nugen Technologies, Inc. Methods of RNA amplification in the presence of DNA
EP3957754A1 (en) 2008-04-21 2022-02-23 Gen-Probe Incorporated Method for detecting chikungunya virus
US8242243B2 (en) 2008-05-15 2012-08-14 Ribomed Biotechnologies, Inc. Methods and reagents for detecting CpG methylation with a methyl CpG binding protein (MBP)
WO2009158119A2 (en) 2008-05-30 2009-12-30 Gen-Probe Incorporated Compositions, kits and related methods for the detection and/or monitoring of salmonella
WO2010009060A2 (en) 2008-07-13 2010-01-21 Ribomed Biotechnologies, Inc. Molecular beacon-based methods for detection of targets using abscription
WO2010011506A2 (en) * 2008-07-23 2010-01-28 The Washington University Risk factors and a therapeutic target for neurodegenerative disorders
GB0814570D0 (en) 2008-08-08 2008-09-17 Diagnostics For The Real World Isolation of nucleic acid
CA2679750A1 (en) 2008-09-23 2010-03-23 Nexus Dx, Inc. Methods for detecting nucleic acids in a sample
US9127312B2 (en) 2011-02-09 2015-09-08 Bio-Rad Laboratories, Inc. Analysis of nucleic acids
US8728764B2 (en) 2008-10-02 2014-05-20 Illumina Cambridge Limited Nucleic acid sample enrichment for sequencing applications
CA2751303C (en) 2009-02-03 2020-09-01 Mdxhealth Sa Methods of detecting colorectal cancer
AU2010213727A1 (en) 2009-02-11 2011-09-29 Orion Genomics Llc Combinations of polymorphisms for determining allele-specific expression of IGF2
WO2010093465A1 (en) 2009-02-11 2010-08-19 Caris Mpi, Inc. Molecular profiling of tumors
EP3257859B1 (en) 2009-02-26 2020-09-23 Gen-Probe Incorporated Assay for detection of human parvovirus nucleic acid
WO2010102823A1 (en) 2009-03-13 2010-09-16 Oncomethylome Sciences Sa Novel markers for bladder cancer detection
CA2755668A1 (en) 2009-03-15 2010-09-23 Ribomed Biotechnologies, Inc. Abscription based molecular detection
BRPI1009873A2 (pt) 2009-03-17 2016-03-08 Glaxosmithkline Biolog Sa detecção aperfeiçoada de expressão gênica
WO2010126913A1 (en) 2009-04-27 2010-11-04 Gen-Probe Incorporated Methods and kits for use in the selective amplification of target sequences
CN102459649A (zh) * 2009-05-29 2012-05-16 肺结核诊断公司 先进的病原体检测和筛选
EP2446057B1 (en) 2009-06-23 2014-11-19 Gen-Probe Incorporated Compositions and methods for detecting nucleic acid from mollicutes
AU2010266234B2 (en) 2009-07-01 2013-07-25 Gen-Probe Incorporated Methods and compositions for nucleic acid amplification
US20110059453A1 (en) * 2009-08-23 2011-03-10 Affymetrix, Inc. Poly(A) Tail Length Measurement by PCR
WO2011032040A1 (en) 2009-09-10 2011-03-17 Centrillion Technology Holding Corporation Methods of targeted sequencing
US10174368B2 (en) 2009-09-10 2019-01-08 Centrillion Technology Holdings Corporation Methods and systems for sequencing long nucleic acids
US8182994B2 (en) 2009-09-15 2012-05-22 Illumina Cambridge Limited Centroid markers for image analysis of high denisty clusters in complex polynucleotide sequencing
WO2011036173A1 (en) 2009-09-24 2011-03-31 Oncomethylome Sciences S.A. Detection and prognosis of cervical cancer
CA2779223A1 (en) 2009-10-27 2011-05-12 Caris Mpi, Inc. Molecular profiling for personalized medicine
EP2504448B1 (en) * 2009-11-25 2016-10-19 Bio-Rad Laboratories, Inc. Methods and compositions for detecting genetic material
US8501122B2 (en) 2009-12-08 2013-08-06 Affymetrix, Inc. Manufacturing and processing polymer arrays
US8835358B2 (en) 2009-12-15 2014-09-16 Cellular Research, Inc. Digital counting of individual molecules by stochastic attachment of diverse labels
US9315857B2 (en) 2009-12-15 2016-04-19 Cellular Research, Inc. Digital counting of individual molecules by stochastic attachment of diverse label-tags
WO2011078439A1 (en) * 2009-12-24 2011-06-30 Seegene, Inc. Real-time multiplexing detection of target nucleic acid sequences with elimination of false signals
EP2529026B1 (en) 2010-01-25 2013-11-13 Rd Biosciences Inc. Self-folding amplification of target nucleic acid
EP3604558B1 (en) 2010-02-17 2022-10-12 Gen-Probe Incorporated Compositions and methods to detect atopobium vaginae nucleic acid
WO2011128096A1 (en) 2010-04-16 2011-10-20 Roche Diagnostics Gmbh Polymorphism markers for predicting response to interleukin-6 receptor-inhibiting monoclonal antibody drug treatment
WO2011133811A2 (en) 2010-04-21 2011-10-27 Gen-Probe Incorporated Compositions, methods and kits to detect herpes simplex virus nucleic acid
WO2011135058A2 (en) 2010-04-30 2011-11-03 Mdxhealth Sa Methods for detecting epigenetic modifications
KR101176139B1 (ko) 2010-05-20 2012-08-22 광주과학기술원 관절염 동물모델로서 연골 특이적 HIF?2α 형질전환 마우스 및 이의 용도
KR101223660B1 (ko) 2010-05-20 2013-01-17 광주과학기술원 HIF-2α 억제제를 유효성분으로 포함하는 관절염 예방 또는 치료용 약제학적 조성물
US20130143214A1 (en) 2010-06-04 2013-06-06 Chronix Biomedical Prostate cancer associated circulating nucleic acid biomarkers
US9234249B2 (en) 2010-07-12 2016-01-12 Gen-Probe Incorporated Compositions and assays to detect swine H1N1 influenza A virus, seasonal H1 influenza A virus and seasonal H3 influenza A virus nucleic acids
CN103543282A (zh) 2010-07-23 2014-01-29 贝克曼考尔特公司 用于处理化验盒的系统
US20130261003A1 (en) 2010-08-06 2013-10-03 Ariosa Diagnostics, In. Ligation-based detection of genetic variants
US20120034603A1 (en) 2010-08-06 2012-02-09 Tandem Diagnostics, Inc. Ligation-based detection of genetic variants
US10167508B2 (en) 2010-08-06 2019-01-01 Ariosa Diagnostics, Inc. Detection of genetic abnormalities
WO2012019168A2 (en) 2010-08-06 2012-02-09 Moderna Therapeutics, Inc. Engineered nucleic acids and methods of use thereof
US20140342940A1 (en) 2011-01-25 2014-11-20 Ariosa Diagnostics, Inc. Detection of Target Nucleic Acids using Hybridization
US11031095B2 (en) 2010-08-06 2021-06-08 Ariosa Diagnostics, Inc. Assay systems for determination of fetal copy number variation
US8700338B2 (en) 2011-01-25 2014-04-15 Ariosa Diagnosis, Inc. Risk calculation for evaluation of fetal aneuploidy
US20130040375A1 (en) 2011-08-08 2013-02-14 Tandem Diagnotics, Inc. Assay systems for genetic analysis
US10533223B2 (en) 2010-08-06 2020-01-14 Ariosa Diagnostics, Inc. Detection of target nucleic acids using hybridization
US11203786B2 (en) 2010-08-06 2021-12-21 Ariosa Diagnostics, Inc. Detection of target nucleic acids using hybridization
EP2606150B1 (en) 2010-08-20 2016-03-16 Life Technologies Corporation Quantitative real-time pcr assay using fret dual-labeled primers
EP2611932A2 (en) 2010-08-30 2013-07-10 Gen-Probe Incorporated Compositions, methods and reaction mixtures for the detection of xenotropic murine leukemia virus-related virus
WO2012040619A2 (en) 2010-09-24 2012-03-29 Massachusetts Eye And Ear Infirmary Methods and compositions for prognosing and/or detecting age-related macular degeneration
CA2821992A1 (en) 2010-10-01 2012-04-05 Moderna Therapeutics, Inc. Engineered nucleic acids and methods of use thereof
EP3438289A1 (en) 2010-10-04 2019-02-06 Gen-Probe Prodesse, Inc. Compositions, methods and kits to detect adenovirus nucleic acids
US9994897B2 (en) 2013-03-08 2018-06-12 Ariosa Diagnostics, Inc. Non-invasive fetal sex determination
US20120190021A1 (en) 2011-01-25 2012-07-26 Aria Diagnostics, Inc. Detection of genetic abnormalities
US11270781B2 (en) 2011-01-25 2022-03-08 Ariosa Diagnostics, Inc. Statistical analysis for non-invasive sex chromosome aneuploidy determination
US10131947B2 (en) 2011-01-25 2018-11-20 Ariosa Diagnostics, Inc. Noninvasive detection of fetal aneuploidy in egg donor pregnancies
US8756020B2 (en) 2011-01-25 2014-06-17 Ariosa Diagnostics, Inc. Enhanced risk probabilities using biomolecule estimations
EP2813851B1 (en) 2011-02-24 2016-06-08 Hill's Pet Nutrition, Inc. Compositions and methods for diagnosing kidney disorders in a feline
WO2012118745A1 (en) 2011-02-28 2012-09-07 Arnold Oliphant Assay systems for detection of aneuploidy and sex determination
USRE49975E1 (en) 2011-03-10 2024-05-21 Gen-Probe Incorporated Methods and compositions for the selection and optimization of oligonucleotide tag sequences
DE12722942T1 (de) 2011-03-31 2021-09-30 Modernatx, Inc. Freisetzung und formulierung von manipulierten nukleinsäuren
US20120252682A1 (en) 2011-04-01 2012-10-04 Maples Corporate Services Limited Methods and systems for sequencing nucleic acids
EP3272886B1 (en) 2011-04-25 2019-09-25 Gen-Probe Incorporated Compositions and methods for detecting bv-associated bacterial nucleic acid
WO2012174294A1 (en) 2011-06-15 2012-12-20 Hill's Pet Nutrition, Inc. Compositions and methods for diagnosing and monitoring hyperthyroidism in a feline
US20140275211A1 (en) 2011-06-21 2014-09-18 Alnylam Pharmaceuticals, Inc. Assays and methods for determining activity of a therapeutic agent in a subject
WO2013012708A1 (en) 2011-07-15 2013-01-24 Gen-Probe Incorporated Compositions and method for detecting human parvovirus nucleic acid and for detecting hepatitis a virus nucleic acids in single-plex or multiplex assays
WO2013024173A1 (en) 2011-08-17 2013-02-21 Technische Universität München Computer implemented method for identifying regulatory regions or regulatory variations
WO2013030167A1 (en) 2011-08-31 2013-03-07 F. Hoffmann-La Roche Ag Responsiveness to angiogenesis inhibitors
AU2012300986A1 (en) 2011-08-31 2014-02-13 F. Hoffmann-La Roche Ag Method for predicting risk of hypertension associated with anti-angiogenesis therapy
US8712697B2 (en) 2011-09-07 2014-04-29 Ariosa Diagnostics, Inc. Determination of copy number variations using binomial probability calculations
AU2012304327B2 (en) 2011-09-08 2015-07-09 Gen-Probe Incorporated Compositions and methods for detecting BV-associated bacterial nucleic acid
US9464124B2 (en) 2011-09-12 2016-10-11 Moderna Therapeutics, Inc. Engineered nucleic acids and methods of use thereof
CN103930111A (zh) 2011-09-19 2014-07-16 霍夫曼-拉罗奇有限公司 包含c-met拮抗剂和b-raf拮抗剂的组合治疗
GB201206209D0 (en) 2012-04-06 2012-05-23 Univ Leuven Kath Marker gene based diagnosis, staging and prognosis of prostate caner
EP3492109B1 (en) 2011-10-03 2020-03-04 ModernaTX, Inc. Modified nucleosides, nucleotides, and nucleic acids, and uses thereof
FR2981088B1 (fr) 2011-10-06 2013-11-29 Biomerieux Sa Arn polymerases mutees
ES2729554T3 (es) 2011-10-21 2019-11-04 Chronix Biomedical Biomarcadores de ácidos nucleicos en circulación asociados al cáncer colorrectal
ES2729283T3 (es) 2011-11-07 2019-10-31 Beckman Coulter Inc Sistema de centrífuga y flujo de trabajo
BR112014011035A2 (pt) 2011-11-07 2017-06-13 Beckman Coulter, Inc. sistema de aliquotagem e fluxo de trabalho
BR112014010955A2 (pt) 2011-11-07 2017-06-06 Beckman Coulter Inc sistema e método para processar amostras
ES2844324T3 (es) 2011-11-07 2021-07-21 Beckman Coulter Inc Brazo robótico
US8973736B2 (en) 2011-11-07 2015-03-10 Beckman Coulter, Inc. Magnetic damping for specimen transport system
KR20140091033A (ko) 2011-11-07 2014-07-18 베크만 컬터, 인코포레이티드 검체 컨테이너 검출
CA2854568A1 (en) 2011-11-23 2013-05-30 Life Sciences Research Partners Vzw Responsiveness to angiogenesis inhibitors
DE102011120550B4 (de) 2011-12-05 2013-11-07 Gen-Probe Prodesse, Inc. Zusammensetzungen, Verfahren und Kits zur Detektion von Adenovirusnukleinsäuren
JP2015501844A (ja) 2011-12-16 2015-01-19 モデルナ セラピューティクス インコーポレイテッドModerna Therapeutics,Inc. 修飾ヌクレオシド、ヌクレオチドおよび核酸組成物
AU2012355775B2 (en) 2011-12-19 2015-10-08 Hill's Pet Nutrition, Inc. Compositions and methods for diagnosing and treating hyperthyroidism in companion animals
US9115394B2 (en) 2011-12-22 2015-08-25 Roche Molecular Systems, Inc. Methods and reagents for reducing non-specific amplification
AU2013205010B2 (en) 2012-02-24 2016-10-20 Gen-Probe Incorporated Detection of Shiga toxin genes in bacteria
CN104364392B (zh) 2012-02-27 2018-05-25 赛卢拉研究公司 用于分子计数的组合物和试剂盒
ES2776673T3 (es) 2012-02-27 2020-07-31 Univ North Carolina Chapel Hill Métodos y usos para etiquetas moleculares
US9572897B2 (en) 2012-04-02 2017-02-21 Modernatx, Inc. Modified polynucleotides for the production of cytoplasmic and cytoskeletal proteins
US9878056B2 (en) 2012-04-02 2018-01-30 Modernatx, Inc. Modified polynucleotides for the production of cosmetic proteins and peptides
US9283287B2 (en) 2012-04-02 2016-03-15 Moderna Therapeutics, Inc. Modified polynucleotides for the production of nuclear proteins
EP2833923A4 (en) 2012-04-02 2016-02-24 Moderna Therapeutics Inc MODIFIED POLYNUCLEOTIDES FOR THE PRODUCTION OF PROTEINS
AU2013205110B2 (en) 2012-04-24 2016-10-13 Gen-Probe Incorporated Compositions, Methods and Kits to Detect Herpes Simplex Virus Nucleic Acids
US10289800B2 (en) 2012-05-21 2019-05-14 Ariosa Diagnostics, Inc. Processes for calculating phased fetal genomic sequences
CN104736722B (zh) 2012-05-21 2018-08-07 斯克利普斯研究所 样品制备方法
GB201208926D0 (en) 2012-05-21 2012-07-04 Vela Operations Pte Ltd Extraction control for DNA
AU2013205064B2 (en) 2012-06-04 2015-07-30 Gen-Probe Incorporated Compositions and Methods for Amplifying and Characterizing HCV Nucleic Acid
AU2013205087B2 (en) 2012-07-13 2016-03-03 Gen-Probe Incorporated Method for detecting a minority genotype
AU2013292287A1 (en) 2012-07-19 2015-02-19 Ariosa Diagnostics, Inc. Multiplexed sequential ligation-based detection of genetic variants
EP2877952B1 (en) 2012-07-27 2023-04-12 Gen-Probe Incorporated Dual reference calibration method and system for quantifying polynucleotides
AU2013202808B2 (en) 2012-07-31 2014-11-13 Gen-Probe Incorporated System and method for performing multiplex thermal melt analysis
CA2883219C (en) 2012-08-30 2020-12-29 Gen-Probe Incorporated Multiphase nucleic acid amplification
BR112015007606A2 (pt) 2012-10-04 2018-01-30 Univ Leland Stanford Junior métodos e reagentes para a detecção, quantificação e serotipagem de vírus da dengue
AU2013205122B2 (en) 2012-10-11 2016-11-10 Gen-Probe Incorporated Compositions and Methods for Detecting Human Papillomavirus Nucleic Acid
LT2922554T (lt) 2012-11-26 2022-06-27 Modernatx, Inc. Terminaliai modifikuota rnr
AU2013205090B2 (en) 2012-12-07 2016-07-28 Gen-Probe Incorporated Compositions and Methods for Detecting Gastrointestinal Pathogen Nucleic Acid
EP2948566A4 (en) 2013-01-24 2016-10-05 California Inst Of Techn CHROMOPHORE-BASED CHARACTERIZATION AND DETECTION METHODS
US10077475B2 (en) 2013-01-24 2018-09-18 California Institute Of Technology FRET-based analytes detection and related methods and systems
WO2014152937A1 (en) 2013-03-14 2014-09-25 Ibis Biosciences, Inc. Nucleic acid control panels
AU2013202805B2 (en) 2013-03-14 2015-07-16 Gen-Probe Incorporated System and method for extending the capabilities of a diagnostic analyzer
US8980864B2 (en) 2013-03-15 2015-03-17 Moderna Therapeutics, Inc. Compositions and methods of altering cholesterol levels
AU2014228343B2 (en) * 2013-03-15 2019-11-07 Gen-Probe Incorporated Calibration method, apparatus and computer program product
KR101403507B1 (ko) 2013-03-21 2014-06-09 주식회사 현일바이오 결핵균 및 비결핵 마이코박테리아의 선택적 검출 방법, 그리고 이를 이용한 키트
JP2016517687A (ja) 2013-03-27 2016-06-20 サンプル テクノロジーズ,インコーポレイティド 組換えファージ及び細菌検出方法
KR101507505B1 (ko) 2013-04-18 2015-04-07 사회복지법인 삼성생명공익재단 제 1 형 근긴장성 이영양증의 진단 방법
HRP20190209T4 (hr) 2013-05-29 2023-09-15 Chronix Biomedical Detekcija i kvantifikacija acelularne dnk darivatelja u krvotoku primatelja presađivanja organa
ES2971972T3 (es) 2013-06-13 2024-06-10 Hoffmann La Roche Análisis estadístico para la determinación no invasiva de aneuploidía del cromosoma Y
CA2915820A1 (en) 2013-06-19 2014-12-24 Michael Sandor Koeris Phage-based bacterial detection assay
WO2015018943A2 (en) 2013-08-08 2015-02-12 Institut Pasteur Correlation of disease activity with clonal expansions of human papillomavirus 16-specific cd8+ t-cells in patients with severe erosive oral lichen planus
CA2920672C (en) 2013-08-14 2022-12-13 Gen-Probe Incorporated Compositions and methods for detecting hev nucleic acid
KR102536833B1 (ko) 2013-08-28 2023-05-26 벡톤 디킨슨 앤드 컴퍼니 대량의 동시 단일 세포 분석
WO2015048744A2 (en) 2013-09-30 2015-04-02 Moderna Therapeutics, Inc. Polynucleotides encoding immune modulating polypeptides
EP3052521A1 (en) 2013-10-03 2016-08-10 Moderna Therapeutics, Inc. Polynucleotides encoding low density lipoprotein receptor
US9582877B2 (en) 2013-10-07 2017-02-28 Cellular Research, Inc. Methods and systems for digitally counting features on arrays
WO2015071759A1 (en) 2013-11-15 2015-05-21 Institut Pasteur A molecular marker of plasmodium falciparum artemisinin resistance
GB201322034D0 (en) 2013-12-12 2014-01-29 Almac Diagnostics Ltd Prostate cancer classification
SG10201808565QA (en) 2014-03-31 2018-11-29 Debiopharm Int Sa Fgfr fusions
EP3191604B1 (en) 2014-09-09 2021-04-14 Igenomx International Genomics Corporation Methods and compositions for rapid nucleic acid library preparation
WO2016077366A1 (en) 2014-11-10 2016-05-19 Genentec, Inc. Therapeutic and diagnostic methods for il-33-mediated disorders
JP6944873B2 (ja) 2015-01-09 2021-10-06 ジェン−プローブ・インコーポレーテッド 細菌性膣症を診断するための方法および組成物
KR101718800B1 (ko) 2015-01-21 2017-03-24 주식회사 디알나노 약물 및 siRNA의 공동―운반용 나노복합체 및 이의 용도
EP3259371B1 (en) 2015-02-19 2020-09-02 Becton, Dickinson and Company High-throughput single-cell analysis combining proteomic and genomic information
EP3262192B1 (en) 2015-02-27 2020-09-16 Becton, Dickinson and Company Spatially addressable molecular barcoding
AU2016233298B2 (en) 2015-03-16 2021-09-02 Gen-Probe Incorporated Methods and compositions for detecting bacterial nucleic acid and diagnosing bacterial vaginosis
US11535882B2 (en) 2015-03-30 2022-12-27 Becton, Dickinson And Company Methods and compositions for combinatorial barcoding
WO2016172373A1 (en) 2015-04-23 2016-10-27 Cellular Research, Inc. Methods and compositions for whole transcriptome amplification
JP6966681B2 (ja) 2015-04-24 2021-11-17 アティラ バイオシステムズ インコーポレイテッドAtila Biosystems Incorporated 限られたヌクレオチド組成を有するプライマーを用いた増幅
WO2016196229A1 (en) 2015-06-01 2016-12-08 Cellular Research, Inc. Methods for rna quantification
GB201510684D0 (en) 2015-06-17 2015-08-05 Almac Diagnostics Ltd Gene signatures predictive of metastatic disease
EP3995589A1 (en) 2015-08-17 2022-05-11 Kura Oncology, Inc. Methods of treating cancer patients with farnesyl transferase inhibitors
US10619186B2 (en) 2015-09-11 2020-04-14 Cellular Research, Inc. Methods and compositions for library normalization
CN108138226B (zh) 2015-10-18 2022-02-11 阿费梅特里克斯公司 单核苷酸多态性和插入缺失的多等位基因基因分型
KR101651817B1 (ko) 2015-10-28 2016-08-29 대한민국 Ngs 라이브러리 제작용 프라이머 세트 및 이를 이용한 ngs 라이브러리 제작방법 및 키트
CA3010232A1 (en) 2016-01-04 2017-07-13 Gen-Probe Incorporated Methods and compositions for detecting candida species
GB201605110D0 (en) 2016-03-24 2016-05-11 Mologic Ltd Detecting sepsis
WO2017184968A1 (en) 2016-04-22 2017-10-26 Kura Oncology, Inc. Methods of selecting cancer patients for treatment with farnesyltransferase inhibitors
EP3452614B1 (en) 2016-05-02 2023-06-28 Becton, Dickinson and Company Accurate molecular barcoding
US10301677B2 (en) 2016-05-25 2019-05-28 Cellular Research, Inc. Normalization of nucleic acid libraries
EP4407625A3 (en) 2016-05-26 2024-10-23 Becton, Dickinson and Company Molecular label counting adjustment methods
US10202641B2 (en) 2016-05-31 2019-02-12 Cellular Research, Inc. Error correction in amplification of samples
US10640763B2 (en) 2016-05-31 2020-05-05 Cellular Research, Inc. Molecular indexing of internal sequences
US10508312B2 (en) 2016-06-10 2019-12-17 Gen-Probe Incorporated Compositions and methods for detecting Zika virus nucleic acid
US20190218623A1 (en) 2016-08-10 2019-07-18 Institut Pasteur Methods and reagents for detecting piperaquine-resistant plasmodium falciparum malaria
CA3034924A1 (en) 2016-09-26 2018-03-29 Cellular Research, Inc. Measurement of protein expression using reagents with barcoded oligonucleotide sequences
EP3529381B1 (en) 2016-10-19 2022-07-06 Gen-Probe Incorporated Compositions and methods for detecting or quantifying hepatitis c virus
CA3042747A1 (en) 2016-11-03 2018-05-11 Kura Oncology, Inc. Methods of treating cancer patients with farnesyltransferase inhibitors
SG11201903158RA (en) 2016-11-08 2019-05-30 Cellular Res Inc Methods for cell label classification
US11164659B2 (en) 2016-11-08 2021-11-02 Becton, Dickinson And Company Methods for expression profile classification
CN110088302A (zh) 2016-11-21 2019-08-02 简·探针公司 用于检测或定量乙型肝炎病毒的组合物和方法
US10427162B2 (en) 2016-12-21 2019-10-01 Quandx Inc. Systems and methods for molecular diagnostics
KR101936799B1 (ko) 2017-01-09 2019-01-11 주식회사 엠이티라이프사이언스 구강전암의 치료용 약학 조성물 및 구강전암 또는 구강암의 예측 또는 진단 방법
US10722880B2 (en) 2017-01-13 2020-07-28 Cellular Research, Inc. Hydrophilic coating of fluidic channels
EP3577232A1 (en) 2017-02-01 2019-12-11 Cellular Research, Inc. Selective amplification using blocking oligonucleotides
CN109475550A (zh) 2017-02-21 2019-03-15 库拉肿瘤学公司 使用法尼基转移酶抑制剂治疗癌症的方法
US10137121B2 (en) 2017-02-21 2018-11-27 Kura Oncology, Inc. Methods of treating cancer with farnesyltransferase inhibitors
US10844425B2 (en) 2017-03-24 2020-11-24 Gen-Probe Incorporated Compositions and methods for detecting or quantifying parainfluenza virus
CA3176536C (en) 2017-03-24 2024-03-05 Gen-Probe Incorporated Compositions and methods for detection of viral pathogens in samples
US11603557B2 (en) 2017-06-02 2023-03-14 Affymetrix, Inc. Array-based methods for analysing mixed samples using differently labelled allele-specific probes
WO2018223053A1 (en) 2017-06-02 2018-12-06 Affymetrix, Inc. Array-based methods for analysing mixed samples using differently labelled allele-specific probes
CA3059559A1 (en) 2017-06-05 2018-12-13 Becton, Dickinson And Company Sample indexing for single cells
AU2018281196B2 (en) 2017-06-07 2022-04-28 Gen-Probe Incorporated Detecting Babesia species nucleic acid in a sample
KR101956315B1 (ko) 2017-07-19 2019-03-08 국민대학교 산학협력단 파킨슨병 바이오마커로서의 miR494 및 이를 이용한 진단키트
WO2019017680A2 (ko) 2017-07-19 2019-01-24 국민대학교 산학협력단 파킨슨병 바이오마커로서의 miRNA 및 이를 이용한 진단키트
US10806730B2 (en) 2017-08-07 2020-10-20 Kura Oncology, Inc. Methods of treating cancer with farnesyltransferase inhibitors
WO2019032489A1 (en) 2017-08-07 2019-02-14 Kura Oncology, Inc. METHODS OF TREATING CANCER WITH FARNESYLTRANSFERASE INHIBITORS
AU2018316218B2 (en) 2017-08-11 2024-07-25 Gen-Probe Incorporated Compositions and methods for detecting Staphylococcus aureus
WO2019094578A1 (en) 2017-11-09 2019-05-16 Alnylam Pharmaceuticals Inc. Assays and methods for determining expression of the lect2 gene
CA3082909C (en) 2017-11-17 2023-07-25 Gen-Probe Incorporated Compositions and methods for detecting c1orf43 nucleic acid
EP3724354A1 (en) 2017-12-15 2020-10-21 Gen-Probe Incorporated Compositions and methods for detecting toxigenic clostridium difficile
CN111492068A (zh) 2017-12-19 2020-08-04 贝克顿迪金森公司 与寡核苷酸相关联的颗粒
CA3226165A1 (en) 2018-02-09 2019-08-15 Genentech, Inc. Therapeutic and diagnostic methods for mast cell-mediated inflammatory diseases
ES2945191T3 (es) 2018-05-03 2023-06-29 Becton Dickinson Co Análisis de muestras multiómicas de alto rendimiento
US11365409B2 (en) 2018-05-03 2022-06-21 Becton, Dickinson And Company Molecular barcoding on opposite transcript ends
GB2597569B (en) 2018-06-13 2023-01-25 Gen Probe Inc Compositions and methods for detecting group B streptococcus nucleic acid
AU2019314449A1 (en) 2018-08-01 2021-03-11 Gen-Probe Incorporated Compositions and methods for detecting nucleic acids of Epstein-Barr virus
AU2019319203A1 (en) 2018-08-08 2021-03-11 Gen-Probe Incorporated Compositions, methods and kits for detecting
AU2019326462A1 (en) 2018-08-21 2021-03-25 Gen-Probe Incorporated Compositions and methods for amplifying, detecting or quantifying human cytomegalovirus
EP3841222A1 (en) 2018-08-24 2021-06-30 Gen-Probe Incorporated Compositions and methods for detecting bacterial nucleic acid and diagnosing bacterial vaginosis
EP3856934A2 (en) 2018-09-27 2021-08-04 Gen-Probe Incorporated COMPOSITIONS AND METHODS FOR DETECTING BORDETELLA PERTUSSIS AND BORDETELLA
PARAPERTUSSIS NUCLEIC ACID
WO2020072380A1 (en) 2018-10-01 2020-04-09 Cellular Research, Inc. Determining 5' transcript sequences
AU2019365821A1 (en) 2018-10-22 2021-06-10 Gen-Probe Incorporated Compositions and methods for amplifying, detecting or quantifying human polyomavirus BK virus
EP3873469A2 (en) 2018-11-01 2021-09-08 Kura Oncology, Inc. Methods of treating cancer with farnesyltransferase inhibitors
WO2020097315A1 (en) 2018-11-08 2020-05-14 Cellular Research, Inc. Whole transcriptome analysis of single cells using random priming
JP7462632B2 (ja) 2018-11-30 2024-04-05 カリス エムピーアイ インコーポレイテッド 次世代分子プロファイリング
WO2020123384A1 (en) 2018-12-13 2020-06-18 Cellular Research, Inc. Selective extension in single cell whole transcriptome analysis
TW202030333A (zh) 2018-12-20 2020-08-16 美商簡 探針公司 用於檢測瘧原蟲物種核酸之組成物及方法
WO2020150356A1 (en) 2019-01-16 2020-07-23 Becton, Dickinson And Company Polymerase chain reaction normalization through primer titration
WO2020154247A1 (en) 2019-01-23 2020-07-30 Cellular Research, Inc. Oligonucleotides associated with antibodies
WO2020167920A1 (en) 2019-02-14 2020-08-20 Cellular Research, Inc. Hybrid targeted and whole transcriptome amplification
GB201902458D0 (en) 2019-02-22 2019-04-10 Mologic Ltd Treatment stratification for an excerbation of inflamation
US20220142983A1 (en) 2019-03-01 2022-05-12 Kura Oncology, Inc. Methods of treating cancer with farnesyltransferase inhibitors
EP3942078A1 (en) 2019-03-22 2022-01-26 Gen-Probe Incorporated Compositions and methods for detecting group a streptococcus
AU2020254492A1 (en) 2019-03-29 2021-11-11 Kura Oncology, Inc. Methods of treating Squamous Cell Carcinomas with farnesyltransferase inhibitors
TW202102218A (zh) 2019-04-01 2021-01-16 美商庫拉腫瘤技術股份有限公司 以法呢基(farnesyl)轉移酶抑制劑治療癌症的方法
CN114051537A (zh) 2019-04-17 2022-02-15 艾基诺米公司 用于早期诊断子宫平滑肌瘤和平滑肌肉瘤的改进方法
US11965208B2 (en) 2019-04-19 2024-04-23 Becton, Dickinson And Company Methods of associating phenotypical data and single cell sequencing data
US20220305001A1 (en) 2019-05-02 2022-09-29 Kura Oncology, Inc. Methods of treating acute myeloid leukemia with farnesyltransferase inhibitors
JP2022540801A (ja) 2019-07-03 2022-09-20 ジェン-プローブ・インコーポレーテッド 試料中のTrichomonas vaginalisの存在を決定する際に使用するためのオリゴヌクレオチド
EP4004231A1 (en) 2019-07-22 2022-06-01 Becton, Dickinson and Company Single cell chromatin immunoprecipitation sequencing assay
JP2022545280A (ja) 2019-08-23 2022-10-26 ジェン-プローブ・インコーポレーテッド Treponema pallidumを検出するための組成物、方法、およびキット
JP7556945B2 (ja) 2019-09-05 2024-09-26 ジェン-プローブ・インコーポレーテッド Chlamydia trachomatis変異体の核酸の検出
GB201914538D0 (en) 2019-10-08 2019-11-20 Momentum Bioscience Ltd Microorganism capture from antimicrobial-containing solution
WO2021092386A1 (en) 2019-11-08 2021-05-14 Becton Dickinson And Company Using random priming to obtain full-length v(d)j information for immune repertoire sequencing
MX2022006589A (es) 2019-12-02 2023-01-11 Caris Mpi Inc Predictor de respuesta de platino pan-cancer.
JP2023503946A (ja) 2019-12-09 2023-02-01 ジェン-プローブ・インコーポレーテッド 乾燥試料からのポリヌクレオチド分析物の定量化
CN115244184A (zh) 2020-01-13 2022-10-25 贝克顿迪金森公司 用于定量蛋白和rna的方法和组合物
CA3167112A1 (en) 2020-01-16 2021-07-22 Dnae Diagnostics Limited Compositions, kits and methods for isolating target polynucleotides
EP4114985A1 (en) 2020-03-04 2023-01-11 Gen-Probe Incorporated Compositions and methods for detecting sars-cov-2 nucleic acid
JP2023516497A (ja) 2020-03-13 2023-04-19 メドイミューン・リミテッド Il33にリスクアレルを有する対象を治療するための治療方法
US20230220499A1 (en) 2020-05-07 2023-07-13 Grifols Diagnostic Solutions Inc. Methods and compositions for detecting sars-cov-2 nucleic acid
WO2021231779A1 (en) 2020-05-14 2021-11-18 Becton, Dickinson And Company Primers for immune repertoire profiling
KR20230007464A (ko) 2020-06-05 2023-01-12 주식회사 씨젠 호흡기 병원체 검출을 위한 검체수송 키트 및 이를 이용한 호흡기 병원체 검출방법
US11932901B2 (en) 2020-07-13 2024-03-19 Becton, Dickinson And Company Target enrichment using nucleic acid probes for scRNAseq
CA3188657A1 (en) 2020-07-17 2022-01-20 Gen-Probe Incorporated Detection of macrolide-resistant mycoplasma genitalium
CN116635533A (zh) 2020-11-20 2023-08-22 贝克顿迪金森公司 高表达的蛋白和低表达的蛋白的谱分析
US20240218469A1 (en) 2021-05-14 2024-07-04 Gen-Probe Incorporated Compositions and methods for detecting human adenovirus nucleic acid
US20240254572A1 (en) 2021-07-01 2024-08-01 Gen-Probe Incorporated Enzyme formulations and reaction mixtures for nucleic acid amplification
GB202110479D0 (en) 2021-07-21 2021-09-01 Dnae Diagnostics Ltd Compositions, kits and methods for sequencing target polynucleotides
EP4373965A1 (en) 2021-07-21 2024-05-29 DNAe Diagnostics Limited Method and system comprising a cartridge for sequencing target polynucleotides
GB202110485D0 (en) 2021-07-21 2021-09-01 Dnae Diagnostics Ltd Compositions, kits and methods for sequencing target polynucleotides
EP4382620A3 (en) 2021-07-27 2024-08-07 Gen-Probe Incorporated Compositions and methods for detecting c. jejuni and at least one of salmonella, c. coli, shigella, and stec
EP4424242A1 (en) 2021-10-29 2024-09-04 Seegene, Inc. Sample collecting swab tool and method for detection of respiratory pathogen
EP4282980A1 (en) 2022-05-23 2023-11-29 Mobidiag Oy Methods for amplifying a nucleic acid
WO2024015331A1 (en) 2022-07-12 2024-01-18 Genentech, Inc. Therapeutic and diagnostic methods for multiple sclerosis
WO2024054924A1 (en) 2022-09-08 2024-03-14 Gen-Probe Incorporated Method of detecting nucleic acid analytes using dual-specificity primers
WO2024081776A1 (en) 2022-10-13 2024-04-18 Gen-Probe Incorporated Cellularity control for nucleic acid assays
WO2024137379A2 (en) 2022-12-19 2024-06-27 Gen-Probe Incorporated Compositions and methods for detecting gastrointestinal pathogens
EP4389887A1 (en) 2022-12-21 2024-06-26 Mobidiag Oy Isolating and lysing cells
EP4389911A1 (en) 2022-12-21 2024-06-26 Mobidiag Oy Methods and systems for isolating an analyte
WO2024161179A1 (en) 2023-01-31 2024-08-08 Mobidiag Oy Compositions and methods for detecting stx nucleic acids
WO2024192338A1 (en) 2023-03-16 2024-09-19 Gen-Probe Incorporated Compositions and methods for detecting gastrointestinal parasites

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4683194A (en) 1984-05-29 1987-07-28 Cetus Corporation Method for detection of polymorphic restriction sites and nucleic acid sequences
AU606043B2 (en) 1985-03-28 1991-01-31 F. Hoffmann-La Roche Ag Detection of viruses by amplification and hybridization
US4683195A (en) * 1986-01-30 1987-07-28 Cetus Corporation Process for amplifying, detecting, and/or-cloning nucleic acid sequences
US4683202A (en) * 1985-03-28 1987-07-28 Cetus Corporation Process for amplifying nucleic acid sequences
DK171161B1 (da) 1985-03-28 1996-07-08 Hoffmann La Roche Fremgangsmåde til påvisning af forekomst eller fravær af mindst én specifik nukleinsyresekvens i en prøve eller til skelnen mellem to forskellige nukleinsyresekvenser i denne prøve
EP0224126A3 (en) * 1985-11-25 1989-02-01 The University of Calgary Covalently linked complementary oligodeoxynucleotides as universal nucleic acid sequencing primer linkers
WO1987003451A1 (en) * 1985-12-05 1987-06-18 Fred Hutchinson Cancer Research Center Anti-sense rna for treatment of retroviral disease states
EP0272098A3 (en) * 1986-12-15 1990-06-06 City Of Hope National Medical Center Method for amplification and detection of rna sequences
IL86724A (en) * 1987-06-19 1995-01-24 Siska Diagnostics Inc Methods and kits for amplification and testing of nucleic acid sequences
JP2774121B2 (ja) * 1987-07-31 1998-07-09 ザ ボード オブ トラスティーズ オブ ザ リーランド スタンフォード ジュニア ユニバーシティ 標的ポリヌクレオチド配列の選択的増幅
EP0400097A1 (de) 1988-04-30 1990-12-05 Korfmacher Trading Gmbh Lagerungs- oder stützmatte, insbesondere für verpackungszwecke
US5130238A (en) * 1988-06-24 1992-07-14 Cangene Corporation Enhanced nucleic acid amplification process
JP2905144B2 (ja) 1995-09-14 1999-06-14 有限会社野々川商事 棒状化粧料容器
DE19636774C2 (de) 1996-09-10 1999-04-22 Herberts Gmbh Verfahren zur Anpassung einer Farbrezeptur

Also Published As

Publication number Publication date
DK153289D0 (da) 1989-03-30
FI891436A (fi) 1989-03-23
IE882348L (en) 1989-01-31
PT88168A (pt) 1989-06-30
JP2774121B2 (ja) 1998-07-09
FI891436A0 (fi) 1989-03-23
EP0682120B1 (en) 2001-02-14
IE72468B1 (en) 1997-04-09
PT88168B (pt) 1995-03-01
DE3855064T2 (de) 1996-08-29
CA1340843C (en) 1999-12-07
DE3856455T2 (de) 2001-07-26
US5437990A (en) 1995-08-01
EP0310229A1 (en) 1989-04-05
JPH02501532A (ja) 1990-05-31
EP0682120A1 (en) 1995-11-15
KR890701764A (ko) 1989-12-21
DE3856455D1 (de) 2001-03-22
EP0310229B1 (en) 1996-03-06
ES2086298T3 (es) 1996-07-01
US6410276B1 (en) 2002-06-25
DE3855064D1 (de) 1996-04-11
ATE135053T1 (de) 1996-03-15
WO1989001050A1 (en) 1989-02-09
KR960013577B1 (ko) 1996-10-09

Similar Documents

Publication Publication Date Title
DK153289D0 (da) Selektiv forstaerkning af maal-polynucleotidsekvenser
ATE238434T1 (de) Eine in kaskaden verlaufende vervielfältigungsreaktion von nukleinsäuren
DE69428252D1 (de) Verfahren zur Verbesserung der Nukleinsäureamplifizierung
FR2724934B1 (fr) Oligonucleotide chimere et son utilisation dans l'obtention de transcrits d'un acide nucleique
DK0675969T3 (da) Fremgangsmåde til mangfoldiggørelse af målrettede nucleinsyresegmenter under anvendelse af grupperet polymerase-kædereaktion
KR920014937A (ko) 사슬 치환에 의한 증폭방법
ATE236269T1 (de) Ein elektrochemiluminescenter nachweis von nukleinsäuren auf basis der selbsttragenden sequenzreplikation
ATE269908T1 (de) Methode zur sequenzierung von nukleinsäuren
ATE251674T1 (de) Verfahren, reagenz und salz zum nachweis und amplifikation von nukleinsäuresequenzen
DE69128077D1 (de) Nuklein-säure amplifikation mit dns abhängigen rns polymerasen aktivität von rns-replikasen
PT87769A (pt) Transcripton-based nucleic acid amplification detection systems
DE69736667D1 (de) Verfahren zum nachweis und amplifikation von nukleinsäuresequenzen unter verbrauch von modifizierten oligonukleotiden mit erhöhter zielschmelztemperatur (tm)
DK342289A (da) Fremgangsmaade til sekvensbestemmelse af en dna-streng og reagenssaet til brug ved fremgangsmaaden
DK0549107T3 (da) Fremgangsmåde til fremstilling af et polynukleotidtil anvendelse ved enkeltprimeramplifikation og phosphorthioatholdige oli
ATE184321T1 (de) Dns-abhängige rns-polymerase-transkripte als reportermoleküle zur signalverstärkung in nukleinsäure-hybridisierungsuntersuchungen
DE69427876D1 (de) Methode zur detektion einer gezielten nukleinsäure
ATE87932T1 (de) Alpha-oligonukleotide.
EP0272098A3 (en) Method for amplification and detection of rna sequences
KR930008138A (ko) 특정한 뉴클레오티드 시퀀스를 포함하는 약독화(弱毒化)된 홍역 백신 바이러스 균주와 그의 완벽한 동정 방법
ATE130634T1 (de) Enzymatisches amplifizierungsverfahren in vitro.
ATE144557T1 (de) Nucleinsäure-proben und verfahren zum nachweis von giardia lamblia
MY111893A (en) Method for detecting a target nucleic acid

Legal Events

Date Code Title Description
AHB Application shelved due to non-payment
PUP Patent expired