ATE251674T1 - Verfahren, reagenz und salz zum nachweis und amplifikation von nukleinsäuresequenzen - Google Patents

Verfahren, reagenz und salz zum nachweis und amplifikation von nukleinsäuresequenzen

Info

Publication number
ATE251674T1
ATE251674T1 AT93918645T AT93918645T ATE251674T1 AT E251674 T1 ATE251674 T1 AT E251674T1 AT 93918645 T AT93918645 T AT 93918645T AT 93918645 T AT93918645 T AT 93918645T AT E251674 T1 ATE251674 T1 AT E251674T1
Authority
AT
Austria
Prior art keywords
detection
nucleic acid
amplification
reagent
salt
Prior art date
Application number
AT93918645T
Other languages
English (en)
Inventor
Craig W Adams
David W Daniels
Original Assignee
Beckman Coulter Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26748925&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ATE251674(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Beckman Coulter Inc filed Critical Beckman Coulter Inc
Application granted granted Critical
Publication of ATE251674T1 publication Critical patent/ATE251674T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6844—Nucleic acid amplification reactions
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6844—Nucleic acid amplification reactions
    • C12Q1/6858—Allele-specific amplification
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6844—Nucleic acid amplification reactions
    • C12Q1/6862—Ligase chain reaction [LCR]

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
AT93918645T 1992-08-04 1993-08-04 Verfahren, reagenz und salz zum nachweis und amplifikation von nukleinsäuresequenzen ATE251674T1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US92505992A 1992-08-04 1992-08-04
US08/068,393 US6180338B1 (en) 1992-08-04 1993-05-27 Method, reagent and kit for the detection and amplification of nucleic acid sequences
PCT/US1993/007342 WO1994003630A2 (en) 1992-08-04 1993-08-04 Method, reagent and kit for the detection and amplification of nucleic acid sequences

Publications (1)

Publication Number Publication Date
ATE251674T1 true ATE251674T1 (de) 2003-10-15

Family

ID=26748925

Family Applications (1)

Application Number Title Priority Date Filing Date
AT93918645T ATE251674T1 (de) 1992-08-04 1993-08-04 Verfahren, reagenz und salz zum nachweis und amplifikation von nukleinsäuresequenzen

Country Status (11)

Country Link
US (1) US6180338B1 (de)
EP (1) EP0658212B1 (de)
JP (1) JPH07509371A (de)
AT (1) ATE251674T1 (de)
AU (1) AU676197B2 (de)
CA (1) CA2141537A1 (de)
DE (1) DE69333242T2 (de)
FI (1) FI950487A (de)
PL (1) PL307341A1 (de)
RU (1) RU95106503A (de)
WO (1) WO1994003630A2 (de)

Families Citing this family (36)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0686200A4 (de) * 1993-01-27 1997-07-02 Oncor Inc Amplifikation von nukleinsäuresequenzen
US7135312B2 (en) 1993-04-15 2006-11-14 University Of Rochester Circular DNA vectors for synthesis of RNA and DNA
US6077668A (en) * 1993-04-15 2000-06-20 University Of Rochester Highly sensitive multimeric nucleic acid probes
US6096880A (en) * 1993-04-15 2000-08-01 University Of Rochester Circular DNA vectors for synthesis of RNA and DNA
AU1911395A (en) * 1994-02-04 1995-08-21 Beckman Instruments, Inc. Method, reagent and kit for the detection and amplification of nucleic acid sequences
DE69427876T2 (de) * 1994-05-23 2002-04-11 Biotronics Corp Methode zur detektion einer gezielten nukleinsäure
US5750341A (en) * 1995-04-17 1998-05-12 Lynx Therapeutics, Inc. DNA sequencing by parallel oligonucleotide extensions
JPH11506605A (ja) * 1995-06-07 1999-06-15 アボツト・ラボラトリーズ 増幅反応におけるバックグラウンドを減少させるためにプローブをマスキングする方法
AU704750B2 (en) 1995-12-05 1999-05-06 Jorn Erland Koch A cascade nucleic acid amplification reaction
US6852487B1 (en) 1996-02-09 2005-02-08 Cornell Research Foundation, Inc. Detection of nucleic acid sequence differences using the ligase detection reaction with addressable arrays
US20020150921A1 (en) * 1996-02-09 2002-10-17 Francis Barany Detection of nucleic acid sequence differences using the ligase detection reaction with addressable arrays
GB9609213D0 (en) * 1996-05-02 1996-07-03 Tepnel Medical Ltd Amplification of nucleic acids
EP1736554B1 (de) * 1996-05-29 2013-10-09 Cornell Research Foundation, Inc. Bestimmung von Unterschieden in der Nukleinsäuresequenz mittels einer Kombination von Ligasebestimmung und Polymerasekettenreaktion
GB9626074D0 (en) 1996-12-16 1997-02-05 Cytocell Ltd Nucleic acids amplification assay
FR2779154B1 (fr) * 1998-05-27 2002-07-12 Bio Merieux Procede d'amplification d'au moins une sequence nucleotidique particuliere et amorces de mise en oeuvre
US6911307B1 (en) 1998-12-08 2005-06-28 Proteus S.A. Method of detection in vitro of a target substance in a sample comprising the labelling of said substance with a reporter gene and with the sequences necessary for the expression of said reporter gene in vitro
FR2786789B1 (fr) * 1998-12-08 2001-12-28 Proteus Methode de detection in vitro d'une sequence d'acide nucleique cible dans un echantillon d'acide nucleique
US6506594B1 (en) * 1999-03-19 2003-01-14 Cornell Res Foundation Inc Detection of nucleic acid sequence differences using the ligase detection reaction with addressable arrays
US6368834B1 (en) * 1999-04-06 2002-04-09 Genome Technologies, Llc PCR genome walking with synthetic primer
JP2001249996A (ja) * 1999-12-28 2001-09-14 Sony Corp ホームドクターシステム、血液収納用カプセルおよび注射装置
US20040146918A1 (en) * 2000-02-18 2004-07-29 Weiner Michael L. Hybrid nucleic acid assembly
US7198924B2 (en) 2000-12-11 2007-04-03 Invitrogen Corporation Methods and compositions for synthesis of nucleic acid molecules using multiple recognition sites
US6942972B2 (en) * 2001-10-24 2005-09-13 Beckman Coulter, Inc. Efficient synthesis of protein-oligonucleotide conjugates
BRPI0408967B8 (pt) 2003-03-31 2021-07-27 Hoffmann La Roche kit e métodos para detecção de um ácido nucléico de vários membros do sorogrupo do vírus da encefalite japonesa em uma amostra biológica sob condições de hibridização rigorosas
ATE489481T1 (de) 2003-09-12 2010-12-15 Univ Cincinnati Verfahren zur risikobeurteilung, überlebensvorhersage und behandlung von herzversagen und anderen leiden auf der grundlage von polymorphismen adrenerger rezeptoren
WO2006031955A2 (en) 2004-09-14 2006-03-23 The Regents Of The University Of Colorado, A Body Corporate Method for treatment with bucindolol based on genetic targeting
US7700287B2 (en) * 2005-01-28 2010-04-20 Life Technologies Corporation Compositions and methods for terminating a sequencing reaction at a specific location in a target DNA template
CN101238221B (zh) 2005-04-12 2011-11-16 Novia公司名下的现场Rcp公司 新型环形探针及其在鉴定生物分子中的用途
ATE483032T1 (de) 2005-04-12 2010-10-15 Olink Ab Verfahren zur herstellung von oligonukleotiden
US7501254B2 (en) * 2006-07-20 2009-03-10 Ghc Technologies, Inc. Methods and compositions for amplification and capture of nucleic acid sequences
GB2466442A (en) * 2008-12-18 2010-06-23 Dublin Inst Of Technology A system to analyze a sample on a slide using Raman spectroscopy on an identified area of interest
KR20210056458A (ko) 2011-05-04 2021-05-18 바이오셉트 인코포레이티드 핵산 서열 변이체를 검출하는 방법
US20150011396A1 (en) 2012-07-09 2015-01-08 Benjamin G. Schroeder Methods for creating directional bisulfite-converted nucleic acid libraries for next generation sequencing
EP2971130A4 (de) 2013-03-15 2016-10-05 Nugen Technologies Inc Sequentielle sequenzierung
WO2015073711A1 (en) * 2013-11-13 2015-05-21 Nugen Technologies, Inc. Compositions and methods for identification of a duplicate sequencing read
US11099202B2 (en) 2017-10-20 2021-08-24 Tecan Genomics, Inc. Reagent delivery system

Family Cites Families (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4883750A (en) 1984-12-13 1989-11-28 Applied Biosystems, Inc. Detection of specific sequences in nucleic acids
US4683202A (en) 1985-03-28 1987-07-28 Cetus Corporation Process for amplifying nucleic acid sequences
US4683195A (en) 1986-01-30 1987-07-28 Cetus Corporation Process for amplifying, detecting, and/or-cloning nucleic acid sequences
CA1338457C (en) 1986-08-22 1996-07-16 Henry A. Erlich Purified thermostable enzyme
IL86164A0 (en) 1987-04-28 1988-11-15 Tamir Biotechnology Ltd Improved dna probes
US5093245A (en) 1988-01-26 1992-03-03 Applied Biosystems Labeling by simultaneous ligation and restriction
IE61148B1 (en) 1988-03-10 1994-10-05 Ici Plc Method of detecting nucleotide sequences
US4988617A (en) 1988-03-25 1991-01-29 California Institute Of Technology Method of detecting a nucleotide change in nucleic acids
WO1989009835A1 (en) 1988-04-08 1989-10-19 The Salk Institute For Biological Studies Ligase-based amplification method
JP2801051B2 (ja) 1988-06-24 1998-09-21 アムジエン・インコーポレーテツド 核酸塩基配列を検出するための方法及び試薬
EP0425563B1 (de) * 1988-07-20 1996-05-15 David Segev Verfahren zur amplifizierung und zum nachweis von nukleinsäuresequenzen
US5185243A (en) 1988-08-25 1993-02-09 Syntex (U.S.A.) Inc. Method for detection of specific nucleic acid sequences
GB2225112A (en) 1988-11-22 1990-05-23 Ici Plc Hybridisation probes
AU627809B2 (en) 1988-12-16 1992-09-03 Abbott Laboratories Isolating thermostable enzymes from engineered mesophiles
US4994370A (en) 1989-01-03 1991-02-19 The United States Of America As Represented By The Department Of Health And Human Services DNA amplification technique
KR950013953B1 (ko) 1990-01-26 1995-11-18 애보트 래보라토리즈 리가제 연쇄 반응에 적용가능한 표적 핵산의 증폭 방법
US5427930A (en) * 1990-01-26 1995-06-27 Abbott Laboratories Amplification of target nucleic acids using gap filling ligase chain reaction
CA2039517C (en) 1990-04-03 2006-11-07 David Segev Dna probe signal amplification
HU218095B (hu) 1990-05-01 2000-05-28 Amgen Inc. Eljárás átvitt szennyeződések csökkentésére, amplifikációs eljárásokban
DK0528882T3 (da) 1990-05-03 2008-01-14 Cornell Res Foundation Inc DNA-amplifikationssystem til påvisning af genetiske sygdomme ved hjælp af termostabil ligase
CA2049879A1 (en) 1990-08-30 1992-03-01 Keith C. Backman Controlled initial target-dependent production of templates for ligase chain reaction
CA2052413C (en) 1990-09-28 2004-07-13 Jeffrey L. Joseph Nucleotides sequences useful as type-specific probes, pcr primers and lcr probes for the amplifications and detection of human papilloma virus, and related kits and methods
AU1911395A (en) * 1994-02-04 1995-08-21 Beckman Instruments, Inc. Method, reagent and kit for the detection and amplification of nucleic acid sequences

Also Published As

Publication number Publication date
RU95106503A (ru) 1997-05-10
AU4802793A (en) 1994-03-03
EP0658212A1 (de) 1995-06-21
FI950487A0 (fi) 1995-02-03
WO1994003630A2 (en) 1994-02-17
JPH07509371A (ja) 1995-10-19
CA2141537A1 (en) 1994-02-17
EP0658212B1 (de) 2003-10-08
DE69333242D1 (de) 2003-11-13
AU676197B2 (en) 1997-03-06
US6180338B1 (en) 2001-01-30
FI950487A (fi) 1995-03-10
DE69333242T2 (de) 2004-08-26
WO1994003630A3 (en) 1994-03-31
PL307341A1 (en) 1995-05-15

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