ATE204333T1 - Verfahren zur dämpfung der fluoreszenz von fluoreszenzmarkierten oligonukleotiden in lösung - Google Patents
Verfahren zur dämpfung der fluoreszenz von fluoreszenzmarkierten oligonukleotiden in lösungInfo
- Publication number
- ATE204333T1 ATE204333T1 AT95117981T AT95117981T ATE204333T1 AT E204333 T1 ATE204333 T1 AT E204333T1 AT 95117981 T AT95117981 T AT 95117981T AT 95117981 T AT95117981 T AT 95117981T AT E204333 T1 ATE204333 T1 AT E204333T1
- Authority
- AT
- Austria
- Prior art keywords
- fluorescence
- label
- oligonucleotide
- labled
- oligonucleotides
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
- C12Q1/6816—Hybridisation assays characterised by the detection means
- C12Q1/6818—Hybridisation assays characterised by the detection means involving interaction of two or more labels, e.g. resonant energy transfer
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
- C12Q1/6816—Hybridisation assays characterised by the detection means
- C12Q1/6823—Release of bound markers
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6844—Nucleic acid amplification reactions
- C12Q1/6851—Quantitative amplification
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US08/347,657 US5571673A (en) | 1994-11-23 | 1994-11-23 | Methods for in-solution quenching of fluorescently labeled oligonucleotide probes |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE204333T1 true ATE204333T1 (de) | 2001-09-15 |
Family
ID=23364666
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT95117981T ATE204333T1 (de) | 1994-11-23 | 1995-11-15 | Verfahren zur dämpfung der fluoreszenz von fluoreszenzmarkierten oligonukleotiden in lösung |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US5571673A (de) |
| EP (1) | EP0713921B1 (de) |
| JP (1) | JP3600333B2 (de) |
| KR (1) | KR100431421B1 (de) |
| CN (1) | CN1131320C (de) |
| AT (1) | ATE204333T1 (de) |
| AU (1) | AU700885B2 (de) |
| CA (1) | CA2163388C (de) |
| DE (1) | DE69522176T2 (de) |
| DK (1) | DK0713921T3 (de) |
| ES (1) | ES2162630T3 (de) |
| NZ (1) | NZ280506A (de) |
| PT (1) | PT713921E (de) |
| RU (1) | RU2149186C1 (de) |
Families Citing this family (76)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5925517A (en) * | 1993-11-12 | 1999-07-20 | The Public Health Research Institute Of The City Of New York, Inc. | Detectably labeled dual conformation oligonucleotide probes, assays and kits |
| US5837442A (en) | 1995-11-29 | 1998-11-17 | Roche Molecular Systems, Inc. | Oligonucleotide primers for amplifying HCV nucleic acid |
| US5763184A (en) | 1996-01-30 | 1998-06-09 | Roche Molecular Systems, Inc. | Nucleotide sequence variation in the ABO glycosyltransferase gene |
| JP3898228B2 (ja) * | 1996-04-12 | 2007-03-28 | ザ パブリック ヘルス リサーチ インスティチュート オブ ザ シティー オブ ニューヨーク インク | 検出プローブ、キット及びアッセイ |
| US5691145A (en) * | 1996-08-27 | 1997-11-25 | Becton, Dickinson And Company | Detection of nucleic acids using G-quartets |
| US7803528B1 (en) | 1997-02-28 | 2010-09-28 | Quest Diagnostics Incorporated | Fluorescence energy transfer by competitive hybridization |
| US6503709B1 (en) | 1997-07-03 | 2003-01-07 | Id Biomedical Corporation | Methods for rapidly detecting methicillin resistant staphylococci |
| AU9220498A (en) | 1997-09-04 | 1999-03-22 | Bayer Corporation | Oligonucleotide probes bearing quenchable fluorescent labels, and methods of usethereof |
| US6289229B1 (en) | 1998-01-20 | 2001-09-11 | Scimed Life Systems, Inc. | Readable probe array for in vivo use |
| US5952202A (en) * | 1998-03-26 | 1999-09-14 | The Perkin Elmer Corporation | Methods using exogenous, internal controls and analogue blocks during nucleic acid amplification |
| GB9815799D0 (en) * | 1998-07-21 | 1998-09-16 | Pharmagene Lab Limited | Quantitative analysis of gene expression |
| US6037130A (en) * | 1998-07-28 | 2000-03-14 | The Public Health Institute Of The City Of New York, Inc. | Wavelength-shifting probes and primers and their use in assays and kits |
| US7235358B2 (en) | 2001-06-08 | 2007-06-26 | Expression Diagnostics, Inc. | Methods and compositions for diagnosing and monitoring transplant rejection |
| US7026121B1 (en) | 2001-06-08 | 2006-04-11 | Expression Diagnostics, Inc. | Methods and compositions for diagnosing and monitoring transplant rejection |
| US6905827B2 (en) | 2001-06-08 | 2005-06-14 | Expression Diagnostics, Inc. | Methods and compositions for diagnosing or monitoring auto immune and chronic inflammatory diseases |
| US20050175987A1 (en) * | 2001-08-23 | 2005-08-11 | Kathrin Jansen | Fluorescent multiplex hpv pcr assays using multiple fluorophores |
| PT2014671E (pt) * | 2002-03-11 | 2010-06-16 | Lab 21 Ltd | Métodos e composições para identificar e caracterizar a hepatite c |
| US7659060B2 (en) * | 2002-09-02 | 2010-02-09 | Toyo Boseki Kabushiki Kaisha | Method for identifying nucleotide polymorphism |
| JP4782668B2 (ja) | 2003-03-31 | 2011-09-28 | エフ．ホフマン−ラ ロシュ アーゲー | 日本脳炎ウィルス血清グループのメンバーを包含する一定のフラビウィルスを検出するための組成物及び方法 |
| WO2004094986A2 (en) | 2003-04-16 | 2004-11-04 | Handylab, Inc. | System and method for electrochemical detection of biological compounds |
| US7892745B2 (en) | 2003-04-24 | 2011-02-22 | Xdx, Inc. | Methods and compositions for diagnosing and monitoring transplant rejection |
| US7939251B2 (en) | 2004-05-06 | 2011-05-10 | Roche Molecular Systems, Inc. | SENP1 as a marker for cancer |
| WO2006029184A2 (en) | 2004-09-08 | 2006-03-16 | Expression Diagnostics, Inc. | Genes useful for diagnosing and monitoring inflammation related disorders |
| US20100003665A1 (en) * | 2005-04-28 | 2010-01-07 | Taddeo Frank J | Real-time HPV PCR Assays |
| US11001881B2 (en) | 2006-08-24 | 2021-05-11 | California Institute Of Technology | Methods for detecting analytes |
| US9133504B2 (en) * | 2006-06-05 | 2015-09-15 | California Institute Of Technology | Real time microarrays |
| US11525156B2 (en) | 2006-07-28 | 2022-12-13 | California Institute Of Technology | Multiplex Q-PCR arrays |
| WO2008014485A2 (en) | 2006-07-28 | 2008-01-31 | California Institute Of Technology | Multiplex q-pcr arrays |
| US7993832B2 (en) | 2006-08-14 | 2011-08-09 | Xdx, Inc. | Methods and compositions for diagnosing and monitoring the status of transplant rejection and immune disorders |
| US11560588B2 (en) | 2006-08-24 | 2023-01-24 | California Institute Of Technology | Multiplex Q-PCR arrays |
| WO2008140484A2 (en) | 2006-11-09 | 2008-11-20 | Xdx, Inc. | Methods for diagnosing and monitoring the status of systemic lupus erythematosus |
| EP2574681B1 (de) | 2007-03-28 | 2016-03-23 | Signal Diagnostics | System und Verfahren zur Hochauflösungsanalyse von Nucleinsäuren zur Detektion von Sequenzabweichungen |
| FR2915208A1 (fr) * | 2007-04-20 | 2008-10-24 | Millipore Corp | Composition comprenant l'association d'edta et de pei pour augmenter la permeabilite des parois des microorganismes et utilisations de ladite composition |
| EP2952588A1 (de) | 2007-08-06 | 2015-12-09 | Orion Genomics, LLC | Einzelnukleotid-polymorphismen zur bestimmung der allelspezifischen expression des igf2-gens |
| JP2009077712A (ja) | 2007-09-11 | 2009-04-16 | F Hoffmann La Roche Ag | Ｂ−Ｒａｆキナーゼ阻害剤に対する感受性についての診断試験 |
| BRPI0908748A2 (pt) * | 2008-03-15 | 2015-07-28 | Hologic Inc | Composições e métodos para análise de moléculas de ácido nucleico durante reações de amplificação |
| US10669574B2 (en) | 2008-11-18 | 2020-06-02 | XCR Diagnostics, Inc. | DNA amplification technology |
| EP2396429B1 (de) | 2009-02-11 | 2015-05-27 | Orion Genomics, LLC | Kombinationen aus polymorphismen zur bestimmung von allelspezifischer igf2-expression |
| WO2011128096A1 (en) | 2010-04-16 | 2011-10-20 | Roche Diagnostics Gmbh | Polymorphism markers for predicting response to interleukin-6 receptor-inhibiting monoclonal antibody drug treatment |
| MX2014002307A (es) | 2011-08-31 | 2014-08-26 | Hoffmann La Roche | Metodo para predecir el riesgo de hipertension asociado a la terapia antiangiogenesis. |
| AU2012300985A1 (en) | 2011-08-31 | 2014-02-13 | F. Hoffmann-La Roche Ag | Responsiveness to angiogenesis inhibitors |
| CN103930111A (zh) | 2011-09-19 | 2014-07-16 | 霍夫曼-拉罗奇有限公司 | 包含c-met拮抗剂和b-raf拮抗剂的组合治疗 |
| RU2014123166A (ru) | 2011-11-23 | 2015-12-27 | Ф.Хоффманн-Ля Рош Аг | Восприимчивость к ингибиторам ангиогенеза |
| US10294529B2 (en) | 2012-04-10 | 2019-05-21 | Life Sciences Research Partners Vzw | Microsatellite instability markers in detection of cancer |
| US10633707B2 (en) | 2012-04-10 | 2020-04-28 | Vib Vzw | Markers for detecting microsatellite instability in cancer and determining synthetic lethality with inhibition of the DNA base excision repair pathway |
| US9828629B2 (en) | 2013-03-15 | 2017-11-28 | Roche Molecular Systems, Inc. | Nucleic acid target identification by structure based probe cleavage |
| AU2014331828B2 (en) | 2013-10-09 | 2020-05-14 | Fluoresentric, Inc. | Multiplex probes |
| US20150176060A1 (en) | 2013-12-20 | 2015-06-25 | Roche Molecular Systems, Inc. | Method For Coding Of Multiple PCR Reactions For Assay Recognition |
| US9637791B2 (en) | 2013-12-20 | 2017-05-02 | Roche Molecular Systems, Inc. | Multiplexed nucleic acid target identification by strucutre based probe cleavage |
| US9243289B2 (en) | 2013-12-23 | 2016-01-26 | Roche Molecular Systems, Inc. | Method for screening reagents used in PCR assays |
| US20160053302A1 (en) | 2014-04-22 | 2016-02-25 | Roche Molecular Systems, Inc. | Method for visual identification of pcr solutions for accurate reaction setup |
| EP3167060B1 (de) | 2014-07-10 | 2021-11-24 | Fluoresentric, Inc. | Dna-amplifikationstechnologie |
| US11708608B2 (en) | 2014-11-10 | 2023-07-25 | Genentech, Inc. | Therapeutic and diagnostic methods for IL-33-mediated disorders |
| US9708647B2 (en) | 2015-03-23 | 2017-07-18 | Insilixa, Inc. | Multiplexed analysis of nucleic acid hybridization thermodynamics using integrated arrays |
| PT3277842T (pt) | 2015-08-17 | 2019-09-05 | Kura Oncology Inc | Métodos de tratamento de doentes com cancro usando inibidores da farnesiltransferase |
| US9499861B1 (en) | 2015-09-10 | 2016-11-22 | Insilixa, Inc. | Methods and systems for multiplex quantitative nucleic acid amplification |
| WO2017155858A1 (en) | 2016-03-07 | 2017-09-14 | Insilixa, Inc. | Nucleic acid sequence identification using solid-phase cyclic single base extension |
| WO2017184968A1 (en) | 2016-04-22 | 2017-10-26 | Kura Oncology, Inc. | Methods of selecting cancer patients for treatment with farnesyltransferase inhibitors |
| WO2017201315A1 (en) | 2016-05-18 | 2017-11-23 | Roche Sequencing Solutions, Inc. | Quantitative real time pcr amplification using an electrowetting-based device |
| KR102468174B1 (ko) | 2016-09-15 | 2022-11-17 | 에프. 호프만-라 로슈 아게 | 멀티플렉스 pcr 수행 방법 |
| EA201991091A1 (ru) | 2016-11-03 | 2019-11-29 | Способы лечения пациентов со злокачественными новообразованиями с применением ингибиторов фарнезилтрансферазы | |
| US11031099B2 (en) | 2016-11-09 | 2021-06-08 | Roche Molecular Systems, Inc. | Detection of sequence variants |
| US9956215B1 (en) | 2017-02-21 | 2018-05-01 | Kura Oncology, Inc. | Methods of treating cancer with farnesyltransferase inhibitors |
| TWI663974B (zh) | 2017-02-21 | 2019-07-01 | 美商庫拉腫瘤技術股份有限公司 | 以法呢基轉移酶(farnesyltransferase)抑制劑治療癌症之方法 |
| US10806730B2 (en) | 2017-08-07 | 2020-10-20 | Kura Oncology, Inc. | Methods of treating cancer with farnesyltransferase inhibitors |
| WO2019032489A1 (en) | 2017-08-07 | 2019-02-14 | Kura Oncology, Inc. | METHODS OF TREATING CANCER WITH FARNESYLTRANSFERASE INHIBITORS |
| JP7418337B2 (ja) | 2018-02-09 | 2024-01-19 | ジェネンテック， インコーポレイテッド | マスト細胞媒介性炎症性疾患の治療法及び診断法 |
| SG11202104296TA (en) | 2018-11-01 | 2021-05-28 | Kura Oncology Inc | Methods of treating cancer with farnesyltransferase inhibitors |
| WO2020180663A1 (en) | 2019-03-01 | 2020-09-10 | Kura Oncology, Inc. | Methods of treating cancer with farnesyltransferase inhibitors |
| JP2022525322A (ja) | 2019-03-14 | 2022-05-12 | インシリクサ， インコーポレイテッド | 時間ゲート蛍光ベースの検出のための方法およびシステム |
| CN113795253A (zh) | 2019-03-29 | 2021-12-14 | 库拉肿瘤学公司 | 用法呢基转移酶抑制剂治疗鳞状细胞癌的方法 |
| TW202102218A (zh) | 2019-04-01 | 2021-01-16 | 美商庫拉腫瘤技術股份有限公司 | 以法呢基(farnesyl)轉移酶抑制劑治療癌症的方法 |
| US20220305001A1 (en) | 2019-05-02 | 2022-09-29 | Kura Oncology, Inc. | Methods of treating acute myeloid leukemia with farnesyltransferase inhibitors |
| JP2023516497A (ja) | 2020-03-13 | 2023-04-19 | メドイミューン・リミテッド | Ｉｌ３３にリスクアレルを有する対象を治療するための治療方法 |
| EP4267764A1 (de) | 2020-12-22 | 2023-11-01 | F. Hoffmann-La Roche AG | Verfahren zur durchführung von multiplexierter echtzeit-pcr unter verwendung von grossen stokes-verschiebungsfluoreszenzfarbstoffen |
| WO2023104812A1 (en) | 2021-12-09 | 2023-06-15 | F. Hoffmann-La Roche Ag | Mass based detection of pcr amplicons |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA1307480C (en) * | 1985-07-10 | 1992-09-15 | Nanibhushan Dattagupta | Prolonged chemiluminescence |
| FR2627590A1 (fr) * | 1988-02-24 | 1989-08-25 | Ire Celltarg Sa | Sonde d'acides nucleiques comportant un nucleotide terminal modifie chimiquement en 5(prime) (oh) en vue de son marquage non radioactif et procedes de preparation |
| AU7579891A (en) * | 1990-03-14 | 1991-10-10 | Regents Of The University Of California, The | Multichromophore fluorescent probes |
| US5210015A (en) * | 1990-08-06 | 1993-05-11 | Hoffman-La Roche Inc. | Homogeneous assay system using the nuclease activity of a nucleic acid polymerase |
| US5994056A (en) * | 1991-05-02 | 1999-11-30 | Roche Molecular Systems, Inc. | Homogeneous methods for nucleic acid amplification and detection |
| JP3494646B2 (ja) * | 1992-06-08 | 2004-02-09 | ジェン−プローブ・インコーポレイテッド | 単核細胞からの核酸の調製 |
| US5491063A (en) * | 1994-09-01 | 1996-02-13 | Hoffmann-La Roche Inc. | Methods for in-solution quenching of fluorescently labeled oligonucleotide probes |
-
1994
- 1994-11-23 US US08/347,657 patent/US5571673A/en not_active Expired - Lifetime
-
1995
- 1995-11-15 AT AT95117981T patent/ATE204333T1/de active
- 1995-11-15 DK DK95117981T patent/DK0713921T3/da active
- 1995-11-15 ES ES95117981T patent/ES2162630T3/es not_active Expired - Lifetime
- 1995-11-15 PT PT95117981T patent/PT713921E/pt unknown
- 1995-11-15 DE DE69522176T patent/DE69522176T2/de not_active Expired - Lifetime
- 1995-11-15 EP EP95117981A patent/EP0713921B1/de not_active Expired - Lifetime
- 1995-11-21 NZ NZ280506A patent/NZ280506A/en not_active IP Right Cessation
- 1995-11-21 CA CA002163388A patent/CA2163388C/en not_active Expired - Lifetime
- 1995-11-22 AU AU39010/95A patent/AU700885B2/en not_active Expired
- 1995-11-22 JP JP30430795A patent/JP3600333B2/ja not_active Expired - Lifetime
- 1995-11-23 RU RU95120014A patent/RU2149186C1/ru active
- 1995-11-23 KR KR1019950043097A patent/KR100431421B1/ko not_active IP Right Cessation
- 1995-11-23 CN CN95121850A patent/CN1131320C/zh not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| RU2149186C1 (ru) | 2000-05-20 |
| CA2163388A1 (en) | 1996-05-24 |
| CN1133888A (zh) | 1996-10-23 |
| CN1131320C (zh) | 2003-12-17 |
| DK0713921T3 (da) | 2001-11-12 |
| JPH08220092A (ja) | 1996-08-30 |
| US5571673A (en) | 1996-11-05 |
| EP0713921B1 (de) | 2001-08-16 |
| DE69522176T2 (de) | 2002-05-29 |
| EP0713921A2 (de) | 1996-05-29 |
| KR100431421B1 (ko) | 2004-12-03 |
| CA2163388C (en) | 2008-01-15 |
| DE69522176D1 (de) | 2001-09-20 |
| AU700885B2 (en) | 1999-01-14 |
| KR960017858A (ko) | 1996-06-17 |
| PT713921E (pt) | 2002-02-28 |
| AU3901095A (en) | 1996-05-30 |
| ES2162630T3 (es) | 2002-01-01 |
| NZ280506A (en) | 1997-07-27 |
| EP0713921A3 (de) | 1996-09-11 |
| JP3600333B2 (ja) | 2004-12-15 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| ATE204333T1 (de) | Verfahren zur dämpfung der fluoreszenz von fluoreszenzmarkierten oligonukleotiden in lösung | |
| DE69531133D1 (de) | Verfahren zur Dämpfung der Fluoreszene in Lösung von Fluoreszenzmarkierten Oligonucleotidsonden | |
| US6447724B1 (en) | DNA sequencing using multiple fluorescent labels being distinguishable by their decay times | |
| ATE545710T1 (de) | Verfahren zur vervielfältigung von nukleinsäuren | |
| DE69937447D1 (de) | Verfahren zur erkennung von nukleinsäuren | |
| FI950487A (fi) | Menetelmä, reagenssi ja testipakkaus nukleiinihapposekvenssien totamiseksi ja monistamiseksi | |
| ATE414096T1 (de) | Verfahren zum nachweis und zur quantifizierung von analyten in komplexen mischungen | |
| ATE206764T1 (de) | Verfahren zum sensitiven nachweis von nukleinsäuren | |
| ES2173670T3 (es) | Procedimiento de identificacion de acidos nucleicos mediante espectrometria de masas laser de desorcion/ionizacion asistidas por matriz. | |
| RU95120014A (ru) | Способы гашения в растворе флуорисцентномеченых олигонуклеотидных зондов | |
| DE60133111D1 (de) | Verfahren zur erkennung und zum assay von nukleinsäuresequenzen | |
| ATE305476T1 (de) | Met/fret markierte amplifikationsoligonukleotide und ihre vewendung in verfahren | |
| DE69622347T2 (de) | Oligonukleotid-Primer für Amplifizierung von HCV-Nukleinsäure | |
| ES543660A0 (es) | Un metodo para determinar una secuencia particular de poli- nucleotidos en un medio de ensayo que contiene acidos nu- cleicos monocatenarios | |
| ATE298804T1 (de) | Verfahren zur nachweis von nukleinsäuren | |
| ATE325893T1 (de) | Fluorometrisches verfahren zur überwachung und zum nachweis von nucleinsäure-amplifizierung | |
| ATE455864T1 (de) | Verfahren zum nachweis von in einer polymerase- kettenreaktion amplifizierten nukleinsäuremolekülen | |
| ATE287969T1 (de) | Amplifizierungsverfahen zum nachweis von zielnukleinsäuren unter verwendung von fluoreszenzenergieübertragung | |
| JP2003506068A5 (de) |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification |