US7501254B2 - Methods and compositions for amplification and capture of nucleic acid sequences - Google Patents
Methods and compositions for amplification and capture of nucleic acid sequences Download PDFInfo
- Publication number
- US7501254B2 US7501254B2 US11/879,966 US87996607A US7501254B2 US 7501254 B2 US7501254 B2 US 7501254B2 US 87996607 A US87996607 A US 87996607A US 7501254 B2 US7501254 B2 US 7501254B2
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- primer
- annealing
- extended
- forward primer
- capture
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6844—Nucleic acid amplification reactions
- C12Q1/6846—Common amplification features
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- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Health & Medical Sciences (AREA)
- Biophysics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Immunology (AREA)
- Microbiology (AREA)
- Molecular Biology (AREA)
- Analytical Chemistry (AREA)
- Physics & Mathematics (AREA)
- Biotechnology (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Abstract
Description
Claims (45)
Priority Applications (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US11/879,966 US7501254B2 (en) | 2006-07-20 | 2007-07-19 | Methods and compositions for amplification and capture of nucleic acid sequences |
PCT/US2007/016531 WO2008011180A2 (en) | 2006-07-20 | 2007-07-20 | Methods and compositions for amplification and capture of nucleic acid sequences |
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US83204906P | 2006-07-20 | 2006-07-20 | |
US92179607P | 2007-04-04 | 2007-04-04 | |
US11/879,966 US7501254B2 (en) | 2006-07-20 | 2007-07-19 | Methods and compositions for amplification and capture of nucleic acid sequences |
Publications (2)
Publication Number | Publication Date |
---|---|
US20080171364A1 US20080171364A1 (en) | 2008-07-17 |
US7501254B2 true US7501254B2 (en) | 2009-03-10 |
Family
ID=38957422
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
US11/879,966 Expired - Fee Related US7501254B2 (en) | 2006-07-20 | 2007-07-19 | Methods and compositions for amplification and capture of nucleic acid sequences |
Country Status (2)
Country | Link |
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US (1) | US7501254B2 (en) |
WO (1) | WO2008011180A2 (en) |
Families Citing this family (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7501254B2 (en) * | 2006-07-20 | 2009-03-10 | Ghc Technologies, Inc. | Methods and compositions for amplification and capture of nucleic acid sequences |
WO2011057354A1 (en) * | 2009-11-13 | 2011-05-19 | Commonwealth Scientific And Industrial Research Organisation | Epigenetic analysis |
MY179753A (en) * | 2013-09-23 | 2020-11-12 | Chow Tai Fook Jewellery Co Ltd | Presentation apparatus (iot) |
CN105354525B (en) * | 2015-12-04 | 2018-08-14 | 威海北洋电气集团股份有限公司 | A kind of lane device and direction recognizing method based on RFID |
Citations (71)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0300796A2 (en) | 1987-07-23 | 1989-01-25 | Syntex (U.S.A.) Inc. | Amplification method for polynucleotide assays |
WO1990014439A1 (en) | 1989-05-26 | 1990-11-29 | Gene-Trak Systems | Target-dependent synthesis of a replicatable rna |
WO1991001384A1 (en) | 1989-07-11 | 1991-02-07 | Gen-Probe, Incorporated | Nucleic acid sequence amplification methods utilizing a transcription complex |
WO1991004340A1 (en) | 1989-09-20 | 1991-04-04 | Cambridge Biotech Corporation | In vitro, isothermal nucleic acid amplification |
US5011769A (en) | 1985-12-05 | 1991-04-30 | Meiogenics U.S. Limited Partnership | Methods for detecting nucleic acid sequences |
WO1992001813A1 (en) | 1990-07-25 | 1992-02-06 | Syngene, Inc. | Circular extension for generating multiple nucleic acid complements |
US5270184A (en) | 1991-11-19 | 1993-12-14 | Becton, Dickinson And Company | Nucleic acid target generation |
US5273879A (en) | 1987-07-23 | 1993-12-28 | Syntex (U.S.A.) Inc. | Amplification method for polynucleotide assays |
US5356774A (en) | 1986-04-16 | 1994-10-18 | The Trustees Of Columbia University In The City Of New York | Replicative RNA-based amplification/detection systems |
WO1995003430A1 (en) | 1993-07-23 | 1995-02-02 | Gen-Probe Incorporated | Methods for enhancing nucleic acid amplification |
US5418149A (en) | 1990-07-24 | 1995-05-23 | Hoffmann-La Roche Inc. | Reduction of non-specific amplification glycosylase using DUTP and DNA uracil |
WO1995025180A1 (en) | 1994-03-16 | 1995-09-21 | Gen-Probe Incorporated | Isothermal strand displacement nucleic acid amplification |
US5471676A (en) | 1989-10-17 | 1995-11-28 | Nakajima All Precision Co., Ltd. | Character data compressing method and character modifying method |
WO1996017079A1 (en) | 1994-11-28 | 1996-06-06 | Akzo Nobel N.V. | Terminal repeat amplification method |
WO1996023904A1 (en) | 1995-02-03 | 1996-08-08 | Replicon, Inc. | Methods for the isothermal amplification of nucleic acid molecules |
US5591609A (en) | 1992-08-04 | 1997-01-07 | Replicon, Inc. | Methods for the isothermal amplification of nucleic acid molecules |
US5648211A (en) | 1994-04-18 | 1997-07-15 | Becton, Dickinson And Company | Strand displacement amplification using thermophilic enzymes |
WO1997027331A2 (en) | 1996-01-23 | 1997-07-31 | Rapigene, Inc. | Methods and compositions for determining the sequence of nucleic acid molecules |
US5674679A (en) | 1991-09-27 | 1997-10-07 | Amersham Life Science, Inc. | DNA cycle sequencing |
US5712124A (en) | 1991-01-31 | 1998-01-27 | Becton, Dickinson And Company | Strand displacement amplification |
EP0826779A1 (en) | 1996-08-22 | 1998-03-04 | Becton, Dickinson and Company | Strand displacement amplification using boronated nucleotides |
WO1998011255A1 (en) | 1996-09-16 | 1998-03-19 | Li-Cor, Inc. | Cycle labeling and sequencing with thermostable polymerases |
US5756285A (en) | 1991-09-27 | 1998-05-26 | Amersham Life Science, Inc. | DNA cycle sequencing |
WO1998038296A1 (en) | 1997-02-27 | 1998-09-03 | Gesher-Israel Advanced Biotecs (1996) Ltd. | Method for simultaneous ligation of multiple dna fragments |
US5814492A (en) | 1995-06-07 | 1998-09-29 | Abbott Laboratories | Probe masking method of reducing background in an amplification reaction |
US5824517A (en) | 1995-07-24 | 1998-10-20 | Bio Merieux | Method for amplifying nucleic acid sequences by strand displacement using DNA/RNA chimeric primers |
WO1999018241A1 (en) | 1997-10-08 | 1999-04-15 | Yale University | Multiple displacement amplification |
US5908744A (en) | 1989-07-11 | 1999-06-01 | Gen-Probe Incorporated | Detecting Mycobacterium tuberculosis by nucleic acid sequence amplification |
EP0971039A2 (en) | 1998-06-24 | 2000-01-12 | Enzo Diagnostics, Inc. | Processes useful for nucleic acid amplification and sequencing, and for the production of nucleic acid having decreased thermodynamic stability |
US6033881A (en) | 1995-06-13 | 2000-03-07 | Himmler; Gottfried | Method for one step isothermal non-transcription based amplification of nucleic acids |
WO2000028084A1 (en) | 1998-11-06 | 2000-05-18 | Molecular Biology Resources, Inc. | Isothermal nucleic acid amplification methods |
WO2000041524A2 (en) | 1999-01-11 | 2000-07-20 | President And Fellows Of Harvard College | Isothermal amplification of dna |
WO2000062036A1 (en) | 1999-04-12 | 2000-10-19 | Nanogen/Becton Dickinson Partnership | Amplification and separation of nucleic acid sequences using strand displacement amplification and bioelectronic microchip technology |
US6143495A (en) | 1995-11-21 | 2000-11-07 | Yale University | Unimolecular segment amplification and sequencing |
WO2000070095A2 (en) | 1999-05-17 | 2000-11-23 | Dade Behring Inc. | Homogeneous isothermal amplification and detection of nucleic acids using a template switch oligonucleotide |
US6180338B1 (en) | 1992-08-04 | 2001-01-30 | Beckman Coulter, Inc. | Method, reagent and kit for the detection and amplification of nucleic acid sequences |
US6207368B1 (en) | 1992-08-04 | 2001-03-27 | Beckman Coulter, Inc. | Methods and reagents for controlling chain extension and ligation chain reactions |
US6225062B1 (en) | 1996-11-12 | 2001-05-01 | Visible Genetics Inc. | Method and kit for direct isothermal sequencing of nucleic acids |
US6225067B1 (en) | 1999-04-13 | 2001-05-01 | BIOMéRIEUX, INC. | Methods and devices for performing analysis of a nucleic acid sample |
US6248567B1 (en) | 2000-04-24 | 2001-06-19 | Wisconsin Alumni Research Foundation | Template-specific termination in a polymerase chain reaction |
US6251639B1 (en) | 1999-09-13 | 2001-06-26 | Nugen Technologies, Inc. | Methods and compositions for linear isothermal amplification of polynucleotide sequences, using a RNA-DNA composite primer |
US6255082B1 (en) | 1998-09-15 | 2001-07-03 | Yale University | Artificial long terminal repeat vectors |
US6261808B1 (en) | 1992-08-04 | 2001-07-17 | Replicon, Inc. | Amplification of nucleic acid molecules via circular replicons |
US20010036629A1 (en) | 1989-06-07 | 2001-11-01 | William J Dower | Sequencing of surface immobilized polymers utilizing microfluorescence detection |
US20020058270A1 (en) | 2000-06-26 | 2002-05-16 | Nurith Kurn | Methods and compositions for transcription-based nucleic acid amplification |
US20020137036A1 (en) | 1999-10-29 | 2002-09-26 | Sorge Joseph A. | Methods for detection of a target nucleic acid by capture |
US20020187477A1 (en) | 2001-06-06 | 2002-12-12 | Hong Xue | Method for detecting single nucleotide polymorphisms (SNPs) and point mutations |
EP1275715A1 (en) | 2000-04-07 | 2003-01-15 | Eiken Kagaku Kabushiki Kaisha | Method for amplifying nucleic acid by using double-stranded nucleic acid as template |
US20030044779A1 (en) | 1991-03-05 | 2003-03-06 | Philip Goelet | Nucleic acid typing by polymerase extension of oligonucleotides using terminator mixtures |
US20030082572A1 (en) | 2001-04-16 | 2003-05-01 | Eugene Spier | Methods and compositions for nucleotide analysis |
US20030087271A1 (en) | 1996-03-01 | 2003-05-08 | Ebersole Richard C. | Method for the amplification and detection of a nucleic acid fragment of interest |
US20030104431A1 (en) | 2001-07-15 | 2003-06-05 | Keck Graduate Institute | Nucleic acid amplification using nicking agents |
US20030143587A1 (en) | 2001-10-15 | 2003-07-31 | Molecular Staging, Inc. | Nucleic acid amplification |
US20030190627A1 (en) | 2002-04-09 | 2003-10-09 | Xiaodong Zhao | Primer extension using modified nucleotides |
US6692918B2 (en) | 1999-09-13 | 2004-02-17 | Nugen Technologies, Inc. | Methods and compositions for linear isothermal amplification of polynucleotide sequences |
US20040038258A1 (en) | 2002-04-29 | 2004-02-26 | Harley John B. | Methods for detecting DNA polymorphisms |
US6716580B2 (en) | 1990-06-11 | 2004-04-06 | Somalogic, Inc. | Method for the automated generation of nucleic acid ligands |
US20040175729A1 (en) | 2002-11-08 | 2004-09-09 | Sysmex Corporation | Primer for nucleic acid amplification to detect carcinoembryonic antigen and test method using such primer |
US6821734B2 (en) | 2001-10-30 | 2004-11-23 | Hitachi, Ltd. | Method for testing nucleic acid sequence |
US20040234996A1 (en) | 2001-10-30 | 2004-11-25 | Ribomed Biotechnologies, Inc. | Molecular detection systems utilizing reiterative oligonucleotide synthesis |
US20040248105A1 (en) | 2003-06-06 | 2004-12-09 | Gyanendra Kumar | Method of whole genome amplification with reduced artifact production |
US20050095610A1 (en) | 2003-04-11 | 2005-05-05 | Kuo Sophia S. | Method of generating size standard nucleic acids |
US20050239109A1 (en) | 2004-03-18 | 2005-10-27 | Atom Sciences | DNA sequence detection by limited primer extension |
US6994963B1 (en) | 2000-07-10 | 2006-02-07 | Ambion, Inc. | Methods for recombinatorial nucleic acid synthesis |
US20060084068A1 (en) | 2004-10-07 | 2006-04-20 | Johnson Mark K | Process for detecting a nucleic acid target |
US20060099607A1 (en) | 2004-11-08 | 2006-05-11 | Yukie Nakashima | Method, apparatus and kit for analyzing sample nucleic acid |
US20060115838A1 (en) | 2004-10-19 | 2006-06-01 | Trevigen Inc. | Real-time detection of amplicons using nucleic acid repair enzymes |
US20060160084A1 (en) | 2002-10-29 | 2006-07-20 | Yasumasa Mitani | Process for amplifying nucleic acid |
US20060160108A1 (en) | 2004-11-10 | 2006-07-20 | Romanov Sergei R | Populations of reporter sequences and methods of their use |
US20060166250A1 (en) | 2005-01-25 | 2006-07-27 | Sydney Brenner | Isothermal DNA amplification |
US20060172333A1 (en) | 2005-01-28 | 2006-08-03 | Applera Corporation | Compositions and methods for terminating a sequencing reaction at a specific location in a target DNA template |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7501254B2 (en) * | 2006-07-20 | 2009-03-10 | Ghc Technologies, Inc. | Methods and compositions for amplification and capture of nucleic acid sequences |
-
2007
- 2007-07-19 US US11/879,966 patent/US7501254B2/en not_active Expired - Fee Related
- 2007-07-20 WO PCT/US2007/016531 patent/WO2008011180A2/en active Application Filing
Patent Citations (97)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5011769A (en) | 1985-12-05 | 1991-04-30 | Meiogenics U.S. Limited Partnership | Methods for detecting nucleic acid sequences |
US5356774A (en) | 1986-04-16 | 1994-10-18 | The Trustees Of Columbia University In The City Of New York | Replicative RNA-based amplification/detection systems |
US5273879A (en) | 1987-07-23 | 1993-12-28 | Syntex (U.S.A.) Inc. | Amplification method for polynucleotide assays |
US5397698A (en) | 1987-07-23 | 1995-03-14 | Syntex (U.S.A.) Inc. | Amplification method for polynucleotide detection assays |
US4994368A (en) | 1987-07-23 | 1991-02-19 | Syntex (U.S.A.) Inc. | Amplification method for polynucleotide assays |
EP0300796A2 (en) | 1987-07-23 | 1989-01-25 | Syntex (U.S.A.) Inc. | Amplification method for polynucleotide assays |
WO1990014439A1 (en) | 1989-05-26 | 1990-11-29 | Gene-Trak Systems | Target-dependent synthesis of a replicatable rna |
US5112734A (en) | 1989-05-26 | 1992-05-12 | Gene-Trak Systems | Target-dependent synthesis of an artificial gene for the synthesis of a replicatable rna |
US20010036629A1 (en) | 1989-06-07 | 2001-11-01 | William J Dower | Sequencing of surface immobilized polymers utilizing microfluorescence detection |
US5908744A (en) | 1989-07-11 | 1999-06-01 | Gen-Probe Incorporated | Detecting Mycobacterium tuberculosis by nucleic acid sequence amplification |
WO1991001384A1 (en) | 1989-07-11 | 1991-02-07 | Gen-Probe, Incorporated | Nucleic acid sequence amplification methods utilizing a transcription complex |
WO1991004340A1 (en) | 1989-09-20 | 1991-04-04 | Cambridge Biotech Corporation | In vitro, isothermal nucleic acid amplification |
US5471676A (en) | 1989-10-17 | 1995-11-28 | Nakajima All Precision Co., Ltd. | Character data compressing method and character modifying method |
US6716580B2 (en) | 1990-06-11 | 2004-04-06 | Somalogic, Inc. | Method for the automated generation of nucleic acid ligands |
US5418149A (en) | 1990-07-24 | 1995-05-23 | Hoffmann-La Roche Inc. | Reduction of non-specific amplification glycosylase using DUTP and DNA uracil |
WO1992001813A1 (en) | 1990-07-25 | 1992-02-06 | Syngene, Inc. | Circular extension for generating multiple nucleic acid complements |
US5712124A (en) | 1991-01-31 | 1998-01-27 | Becton, Dickinson And Company | Strand displacement amplification |
US20030044779A1 (en) | 1991-03-05 | 2003-03-06 | Philip Goelet | Nucleic acid typing by polymerase extension of oligonucleotides using terminator mixtures |
US5756285A (en) | 1991-09-27 | 1998-05-26 | Amersham Life Science, Inc. | DNA cycle sequencing |
US5674679A (en) | 1991-09-27 | 1997-10-07 | Amersham Life Science, Inc. | DNA cycle sequencing |
US5741640A (en) | 1991-09-27 | 1998-04-21 | Amersham Life Science, Inc. | DNA cycle sequencing |
US5270184A (en) | 1991-11-19 | 1993-12-14 | Becton, Dickinson And Company | Nucleic acid target generation |
US5591609A (en) | 1992-08-04 | 1997-01-07 | Replicon, Inc. | Methods for the isothermal amplification of nucleic acid molecules |
US6261808B1 (en) | 1992-08-04 | 2001-07-17 | Replicon, Inc. | Amplification of nucleic acid molecules via circular replicons |
US6207368B1 (en) | 1992-08-04 | 2001-03-27 | Beckman Coulter, Inc. | Methods and reagents for controlling chain extension and ligation chain reactions |
US6180338B1 (en) | 1992-08-04 | 2001-01-30 | Beckman Coulter, Inc. | Method, reagent and kit for the detection and amplification of nucleic acid sequences |
WO1995003430A1 (en) | 1993-07-23 | 1995-02-02 | Gen-Probe Incorporated | Methods for enhancing nucleic acid amplification |
USRE39007E1 (en) | 1994-03-16 | 2006-03-07 | Gen-Probe Incorporated | Isothermal strand displacement nucleic acid amplification |
US6214587B1 (en) | 1994-03-16 | 2001-04-10 | Gen-Probe Incorporated | Isothermal strand displacement nucleic acid amplification |
USRE38960E1 (en) | 1994-03-16 | 2006-01-31 | Gen-Probe Incorporated | Isothermal strand displacement nucleic acid amplification |
WO1995025180A1 (en) | 1994-03-16 | 1995-09-21 | Gen-Probe Incorporated | Isothermal strand displacement nucleic acid amplification |
US6087133A (en) | 1994-03-16 | 2000-07-11 | Gen-Probe Incorporated | Isothermal strand displacement nucleic acid amplification |
US5744311A (en) | 1994-04-18 | 1998-04-28 | Becton, Dickinson And Company | Strand displacement amplification using thermophilic enzymes |
US5648211A (en) | 1994-04-18 | 1997-07-15 | Becton, Dickinson And Company | Strand displacement amplification using thermophilic enzymes |
WO1996017079A1 (en) | 1994-11-28 | 1996-06-06 | Akzo Nobel N.V. | Terminal repeat amplification method |
WO1996023904A1 (en) | 1995-02-03 | 1996-08-08 | Replicon, Inc. | Methods for the isothermal amplification of nucleic acid molecules |
US5814492A (en) | 1995-06-07 | 1998-09-29 | Abbott Laboratories | Probe masking method of reducing background in an amplification reaction |
US6033881A (en) | 1995-06-13 | 2000-03-07 | Himmler; Gottfried | Method for one step isothermal non-transcription based amplification of nucleic acids |
US5824517A (en) | 1995-07-24 | 1998-10-20 | Bio Merieux | Method for amplifying nucleic acid sequences by strand displacement using DNA/RNA chimeric primers |
US6143495A (en) | 1995-11-21 | 2000-11-07 | Yale University | Unimolecular segment amplification and sequencing |
WO1997027331A2 (en) | 1996-01-23 | 1997-07-31 | Rapigene, Inc. | Methods and compositions for determining the sequence of nucleic acid molecules |
US20030087271A1 (en) | 1996-03-01 | 2003-05-08 | Ebersole Richard C. | Method for the amplification and detection of a nucleic acid fragment of interest |
JPH1066589A (en) | 1996-08-22 | 1998-03-10 | Becton Dickinson & Co | Strand displacement amplification with boronated nucleotide |
EP0826779A1 (en) | 1996-08-22 | 1998-03-04 | Becton, Dickinson and Company | Strand displacement amplification using boronated nucleotides |
WO1998011255A1 (en) | 1996-09-16 | 1998-03-19 | Li-Cor, Inc. | Cycle labeling and sequencing with thermostable polymerases |
US6225062B1 (en) | 1996-11-12 | 2001-05-01 | Visible Genetics Inc. | Method and kit for direct isothermal sequencing of nucleic acids |
WO1998038296A1 (en) | 1997-02-27 | 1998-09-03 | Gesher-Israel Advanced Biotecs (1996) Ltd. | Method for simultaneous ligation of multiple dna fragments |
US20040063144A1 (en) | 1997-10-08 | 2004-04-01 | Lizardi Paul M. | Multiple displacement amplification |
US6124120A (en) | 1997-10-08 | 2000-09-26 | Yale University | Multiple displacement amplification |
WO1999018241A1 (en) | 1997-10-08 | 1999-04-15 | Yale University | Multiple displacement amplification |
US6280949B1 (en) | 1997-10-08 | 2001-08-28 | Yale University | Multiple displacement amplification |
US6642034B2 (en) | 1997-10-08 | 2003-11-04 | Yale University | Multiple displacement amplification |
US20030143536A1 (en) | 1997-10-08 | 2003-07-31 | Yale University | Multiple displacement amplification |
EP0971039A2 (en) | 1998-06-24 | 2000-01-12 | Enzo Diagnostics, Inc. | Processes useful for nucleic acid amplification and sequencing, and for the production of nucleic acid having decreased thermodynamic stability |
US20050260573A1 (en) | 1998-06-24 | 2005-11-24 | Elazar Rabbani | Novel processes for non-linearly amplifying nucleic acids using a primer with three segments |
US6255082B1 (en) | 1998-09-15 | 2001-07-03 | Yale University | Artificial long terminal repeat vectors |
WO2000028084A1 (en) | 1998-11-06 | 2000-05-18 | Molecular Biology Resources, Inc. | Isothermal nucleic acid amplification methods |
WO2000041524A2 (en) | 1999-01-11 | 2000-07-20 | President And Fellows Of Harvard College | Isothermal amplification of dna |
US20050164213A1 (en) | 1999-01-11 | 2005-07-28 | Stanley Tabor | Isothermal amplification of DNA |
WO2000062036A1 (en) | 1999-04-12 | 2000-10-19 | Nanogen/Becton Dickinson Partnership | Amplification and separation of nucleic acid sequences using strand displacement amplification and bioelectronic microchip technology |
US20030104430A1 (en) | 1999-04-12 | 2003-06-05 | Nerenberg Michael I. | Amplification and separation of nucleic acid sequences using strand displacement amplification and bioelectronic microchip technology |
US6225067B1 (en) | 1999-04-13 | 2001-05-01 | BIOMéRIEUX, INC. | Methods and devices for performing analysis of a nucleic acid sample |
WO2000070095A2 (en) | 1999-05-17 | 2000-11-23 | Dade Behring Inc. | Homogeneous isothermal amplification and detection of nucleic acids using a template switch oligonucleotide |
US6692918B2 (en) | 1999-09-13 | 2004-02-17 | Nugen Technologies, Inc. | Methods and compositions for linear isothermal amplification of polynucleotide sequences |
US6251639B1 (en) | 1999-09-13 | 2001-06-26 | Nugen Technologies, Inc. | Methods and compositions for linear isothermal amplification of polynucleotide sequences, using a RNA-DNA composite primer |
US20040203025A1 (en) | 1999-09-13 | 2004-10-14 | Nurith Kurn | Methods and compositions for linear isothermal amplification of polynucleotide sequences using a RNA DNA composite primer |
US20020137036A1 (en) | 1999-10-29 | 2002-09-26 | Sorge Joseph A. | Methods for detection of a target nucleic acid by capture |
EP1275715A1 (en) | 2000-04-07 | 2003-01-15 | Eiken Kagaku Kabushiki Kaisha | Method for amplifying nucleic acid by using double-stranded nucleic acid as template |
US20030207292A1 (en) | 2000-04-07 | 2003-11-06 | Tsugunori Notomi | Method of amplifying nucleic acid by using double-stranded nucleic acid as template |
US6248567B1 (en) | 2000-04-24 | 2001-06-19 | Wisconsin Alumni Research Foundation | Template-specific termination in a polymerase chain reaction |
US20040203019A1 (en) | 2000-06-26 | 2004-10-14 | Nurith Kurn | Methods and compositions for transcription-based nucleic acid amplification |
US6686156B2 (en) | 2000-06-26 | 2004-02-03 | Nugen Technologies, Inc. | Methods and compositions for transcription-based nucleic acid amplification |
US20020058270A1 (en) | 2000-06-26 | 2002-05-16 | Nurith Kurn | Methods and compositions for transcription-based nucleic acid amplification |
US6994963B1 (en) | 2000-07-10 | 2006-02-07 | Ambion, Inc. | Methods for recombinatorial nucleic acid synthesis |
US20030082572A1 (en) | 2001-04-16 | 2003-05-01 | Eugene Spier | Methods and compositions for nucleotide analysis |
US6825010B2 (en) | 2001-04-16 | 2004-11-30 | Applera Corporation | Methods and compositions for nucleotide analysis |
US20030017487A1 (en) | 2001-06-06 | 2003-01-23 | Pharmacogenetics, Ltd. | Method for detecting single nucleotide polymorphisms (SNP'S) and point mutations |
US20020187477A1 (en) | 2001-06-06 | 2002-12-12 | Hong Xue | Method for detecting single nucleotide polymorphisms (SNPs) and point mutations |
US6972174B2 (en) | 2001-06-06 | 2005-12-06 | Pharmacogenetics, Ltd. | Method for detecting single nucleotide polymorphisms (SNP's) and point mutations |
US20030104431A1 (en) | 2001-07-15 | 2003-06-05 | Keck Graduate Institute | Nucleic acid amplification using nicking agents |
US7074600B2 (en) | 2001-10-15 | 2006-07-11 | Qiagen Gmbh | Amplification of denatured and stabilized nucleic acids |
US20030143587A1 (en) | 2001-10-15 | 2003-07-31 | Molecular Staging, Inc. | Nucleic acid amplification |
US6821734B2 (en) | 2001-10-30 | 2004-11-23 | Hitachi, Ltd. | Method for testing nucleic acid sequence |
US20040234996A1 (en) | 2001-10-30 | 2004-11-25 | Ribomed Biotechnologies, Inc. | Molecular detection systems utilizing reiterative oligonucleotide synthesis |
US20030190627A1 (en) | 2002-04-09 | 2003-10-09 | Xiaodong Zhao | Primer extension using modified nucleotides |
US20040038258A1 (en) | 2002-04-29 | 2004-02-26 | Harley John B. | Methods for detecting DNA polymorphisms |
US20060160084A1 (en) | 2002-10-29 | 2006-07-20 | Yasumasa Mitani | Process for amplifying nucleic acid |
US20040175729A1 (en) | 2002-11-08 | 2004-09-09 | Sysmex Corporation | Primer for nucleic acid amplification to detect carcinoembryonic antigen and test method using such primer |
US20050095610A1 (en) | 2003-04-11 | 2005-05-05 | Kuo Sophia S. | Method of generating size standard nucleic acids |
US20040248105A1 (en) | 2003-06-06 | 2004-12-09 | Gyanendra Kumar | Method of whole genome amplification with reduced artifact production |
US20050239109A1 (en) | 2004-03-18 | 2005-10-27 | Atom Sciences | DNA sequence detection by limited primer extension |
US20060084068A1 (en) | 2004-10-07 | 2006-04-20 | Johnson Mark K | Process for detecting a nucleic acid target |
US20060115838A1 (en) | 2004-10-19 | 2006-06-01 | Trevigen Inc. | Real-time detection of amplicons using nucleic acid repair enzymes |
US20060099607A1 (en) | 2004-11-08 | 2006-05-11 | Yukie Nakashima | Method, apparatus and kit for analyzing sample nucleic acid |
US20060160108A1 (en) | 2004-11-10 | 2006-07-20 | Romanov Sergei R | Populations of reporter sequences and methods of their use |
US20060166250A1 (en) | 2005-01-25 | 2006-07-27 | Sydney Brenner | Isothermal DNA amplification |
US20060172333A1 (en) | 2005-01-28 | 2006-08-03 | Applera Corporation | Compositions and methods for terminating a sequencing reaction at a specific location in a target DNA template |
Non-Patent Citations (15)
Title |
---|
Elias-Arnanz, Montserrat and Salas, Margarita, Bacteriophage ø29 DNA replication arrest caused by codirectional collisions with the transcription machinery, The EMBO Journal, vol. 16, No. 18, pp. 5775-5783, 1997; Oxford University Press, US. |
Estrada, G. et al.Sequence-specific detection of PCR-amplified DNA by restriction enzyme release of hybrids, Molecular and Cellular Probes Journal, 1996, pp. 179-185, vol. 10, Issue 3, Department of Molecular Recognition and Structural Biology, Univerisad Nacional Autonoma de Mexico, Cuernavaca, Morelos, Mexico. |
Kramer, F. R. and Lizardi, P. M.; Amplifiable Hybridization Probes, National Library of Medicine, NDN-238-0844-0319-1, Ann. Biol. Clin., 1990, pp. 409-411, vol. 48, issue 6, Paris, France. |
Lizardi, P. M.; Kramer, F. R.; Exponential Amplification of Nucleic Acids: New Diagnostics using DNA Polymerases and RNA Replicases, Trends in Biotechnology, Feb. 1990, pp. 53-58, vol. 9, No. 2, London, UK. |
Lomell, H.; Lizardi, P. M. et al. ; Quantitative Assays Based on the use of Replicatable Amplifiable Hybridization Probes, National Library of Medicine, NDN-238-0802-5109-9, Clinical Chemistry, Sep. 1989, pp. 1826-1831, vol. 35, issue 9, Clin. Chem. US. |
Lvovksy, L. et al.; Interdependence between DNA template secondary structure and priming efficiencies of short primers, Nucleic Acids Research, Dec. 1, 1998, pp. 5525-5532, Department of Structural Biology, Weizmann Institute of Science, Rehovot 76100, Israel. |
Nelson, Scott W; Yang, Jingsong; Benkovic, Stephen J, Site-directed Mutations of T4 Helicase Loading Protein (gp59) Reveal Multiple Modes of DNA Polymerase Inhibition and the Mechanism of Unlocking by gp41 Helicase, Journal of Biological Chemistry, Mar. 31, 2006, pp. 8697-8706, vol. 281, No. 13, Stanford University, University Park, PA 16802, US. |
Nimonkar, Amitabh V. and Boehmer, Paul E; Reconstitution of recombination-dependent DNA synthesis in herpes simplex virus 1, PNAS, Sep. 2, 2003, vol. 100, No. 18, pp. 10201-10206, Department of Biochemistry and Molecular Biology, University of Miami School of Medicine, Miami FL 33101-6129, US. |
Nycz, C.M. et al.; Quantitive Reverse Transcription Strand Displacement Amplification: Quantitation of Nucleic Acids Using an Isothermal Amplification Technique, Anal. Biochemistry, Jun. 1, 1998, pp. 226-234, Dept. of Molecular Biology, Becton Dickinson Research Center, Research Triangle Park, North Carolina 22709-2016, US. |
Walker, G.T. et al. ; A DNA Probe Assay Using Strand Displacement Amplification (SDA) and Filtration to Separate Reacted and Unreacted Detector Probes, National Library of Medicine, NDN-237-1079-6976-6, Molecular Cell Probes Journal, Dec. 1995, pp. 399-403, Academic Press, US. |
Walker, G.T. et al.; DNA Detection by Strand Displacement Amplification and Fluorescence Polarization with Signal Enhancement using a DNA binding protein, Nucleic Acids Research Journal, Jan. 15, 1996, pp. 348-353, vol. 24, Issue 2, Becton Dickinson Research Center, Research Triangle Park, North Carolina 22709-2016, US. |
Walker, G.T. et al.; Isothermal in vitro amplification of DNA by a restriction enzyme/DNA polymerase system, Proc National Academy Science USA Journal, Jan. 1, 1992, pp. 392-396, vol. 89, Issue 1, Dept. of Molecular Biology, Becton Dickinson Research Center, Research Triangle Park, North Carolina 22709-2016, US. |
Walker, G.Terrance ; Empirical Aspects of Strand Displacement Amplification, PCR Methods Appl., Aug. 1993, pp. 1-6, vol. 3, Issue 1, Becton Dickinson Research Center, Research Triangle Park, North Carolina 22709-2016, US. |
Walker, G.Terrance et al; Strand displacement amplification-an isothermal, in vitro DNA Amplification Technique, Nucleic Acids Research, Apr. 11, 1992, pp. 1691-1696, vol. 20, Issue 7, 1992 Oxford University Press US. |
Zevin-Sonkin, D. et al.; DENS (differential extension with nucleotide subsets): application to the sequencing of human genomic DNA and cDNA, DNA Sequence 1999, pp. 245-254, Department of Structural Biology, Weizmann Institute of Science, Rehovot, Israel. |
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