ES2091225T3 - Metodos para la amplificacion de las secuencias de acidos nucleicos. - Google Patents

Metodos para la amplificacion de las secuencias de acidos nucleicos.

Info

Publication number
ES2091225T3
ES2091225T3 ES90307503T ES90307503T ES2091225T3 ES 2091225 T3 ES2091225 T3 ES 2091225T3 ES 90307503 T ES90307503 T ES 90307503T ES 90307503 T ES90307503 T ES 90307503T ES 2091225 T3 ES2091225 T3 ES 2091225T3
Authority
ES
Spain
Prior art keywords
nucleic acid
methods
copies
acid sequences
amplification
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES90307503T
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English (en)
Inventor
Daniel Louis Kacian
Timothy J Fultz
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Gen Probe Inc
Original Assignee
Gen Probe Inc
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Filing date
Publication date
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Publication of ES2091225T3 publication Critical patent/ES2091225T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/70—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving virus or bacteriophage
    • C12Q1/701—Specific hybridization probes
    • C12Q1/706—Specific hybridization probes for hepatitis
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6844—Nucleic acid amplification reactions
    • C12Q1/6865—Promoter-based amplification, e.g. nucleic acid sequence amplification [NASBA], self-sustained sequence replication [3SR] or transcription-based amplification system [TAS]
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6888—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms
    • C12Q1/689—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms for bacteria
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/70—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving virus or bacteriophage
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/70—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving virus or bacteriophage
    • C12Q1/701—Specific hybridization probes
    • C12Q1/702—Specific hybridization probes for retroviruses
    • C12Q1/703—Viruses associated with AIDS
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/156—Polymorphic or mutational markers
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/158—Expression markers

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Analytical Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Microbiology (AREA)
  • Virology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Communicable Diseases (AREA)
  • AIDS & HIV (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Saccharide Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)

Abstract

METODOS DE SINTETIZACION DE COPIAS MULTIPOLES DE UNA SECUENCIA DE ACIDO NUCLEICO DE DESTINO AUTOCATALITICAMENTE BAJO CONDICIONES DE TEMPERATURA SUSTANCIALMENTE CONSTANTE, RESISTENCIA IONICA Y PH, EN LOS QUE LAS COPIAS MULTIPLES DE RNA DE LA SECUENCIA DE DESTINO GENERAL GENERAN AUTOCATALITICAMENTE COPIAS ADICIONALES. ESTOS METODOS RESULTAN DE GRAN UTILIDAD EN LA GENERACION DE COPIAS DE SECUENCIAS DE DESTINO DE ACIDO NUCLEICO, QUE INCLUYE MUESTRAS PARA CUANTIFICAR LAS SECUENCIAS ESPECIFICAS DE ACIDO NUCLEICO EN MUESTRAS CLINICAS, AMBIENTALES, FORENSES Y SIMILARES, ASI COMO EN LA GENERACION DE CLONOS Y PRUEBAS.
ES90307503T 1989-07-11 1990-07-10 Metodos para la amplificacion de las secuencias de acidos nucleicos. Expired - Lifetime ES2091225T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US37950189A 1989-07-11 1989-07-11

Publications (1)

Publication Number Publication Date
ES2091225T3 true ES2091225T3 (es) 1996-11-01

Family

ID=23497522

Family Applications (1)

Application Number Title Priority Date Filing Date
ES90307503T Expired - Lifetime ES2091225T3 (es) 1989-07-11 1990-07-10 Metodos para la amplificacion de las secuencias de acidos nucleicos.

Country Status (15)

Country Link
US (1) US5480784A (es)
EP (3) EP0731174B1 (es)
JP (4) JP3241717B2 (es)
KR (1) KR100242252B1 (es)
AT (2) ATE141956T1 (es)
AU (2) AU650622B2 (es)
DE (2) DE69034177T2 (es)
DK (1) DK0408295T3 (es)
ES (1) ES2091225T3 (es)
FI (1) FI911152A0 (es)
GR (1) GR3021704T3 (es)
IE (1) IE902539A1 (es)
NO (1) NO910902D0 (es)
PT (1) PT94662A (es)
WO (1) WO1991001384A1 (es)

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IE902539A1 (en) 1991-02-27
KR920701478A (ko) 1992-08-11
GR3021704T3 (en) 1997-02-28
DE69028257T2 (de) 1997-01-09
EP0731174A3 (en) 1998-03-25
DK0408295T3 (da) 1996-09-16
JP2000350592A (ja) 2000-12-19
DE69034177T2 (de) 2005-10-27
EP0408295A3 (en) 1991-08-28
DE69034177D1 (de) 2004-12-23
ATE141956T1 (de) 1996-09-15
US5480784A (en) 1996-01-02
EP0731174B1 (en) 2004-11-17
JPH1146778A (ja) 1999-02-23
AU650622B2 (en) 1994-06-30
EP0731174A2 (en) 1996-09-11
WO1991001384A1 (en) 1991-02-07
EP0731175A3 (en) 2004-05-26
JP2002355099A (ja) 2002-12-10
FI911152A0 (fi) 1991-03-07
JP3350511B2 (ja) 2002-11-25
EP0731175A2 (en) 1996-09-11
EP0408295B1 (en) 1996-08-28
PT94662A (pt) 1991-03-20
JP3241717B2 (ja) 2001-12-25
AU6166390A (en) 1991-02-22
DE69028257D1 (de) 1996-10-02
JP3445131B2 (ja) 2003-09-08
KR100242252B1 (ko) 2000-03-02
ATE282716T1 (de) 2004-12-15
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