ZA918965B - Nucleic acid amplification by two-enzyme,self-sustained sequence replication - Google Patents
Nucleic acid amplification by two-enzyme,self-sustained sequence replicationInfo
- Publication number
- ZA918965B ZA918965B ZA918965A ZA918965A ZA918965B ZA 918965 B ZA918965 B ZA 918965B ZA 918965 A ZA918965 A ZA 918965A ZA 918965 A ZA918965 A ZA 918965A ZA 918965 B ZA918965 B ZA 918965B
- Authority
- ZA
- South Africa
- Prior art keywords
- enzyme
- self
- nucleic acid
- acid amplification
- sequence replication
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6844—Nucleic acid amplification reactions
- C12Q1/6865—Promoter-based amplification, e.g. nucleic acid sequence amplification [NASBA], self-sustained sequence replication [3SR] or transcription-based amplification system [TAS]
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Genetics & Genomics (AREA)
- General Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Physics & Mathematics (AREA)
- Biomedical Technology (AREA)
- Microbiology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- General Health & Medical Sciences (AREA)
- Analytical Chemistry (AREA)
- Immunology (AREA)
- Crystallography & Structural Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Plant Pathology (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Cosmetics (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Enzymes And Modification Thereof (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US61268890A | 1990-11-13 | 1990-11-13 |
Publications (1)
Publication Number | Publication Date |
---|---|
ZA918965B true ZA918965B (en) | 1992-08-26 |
Family
ID=24454235
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ZA918965A ZA918965B (en) | 1990-11-13 | 1991-11-12 | Nucleic acid amplification by two-enzyme,self-sustained sequence replication |
Country Status (13)
Country | Link |
---|---|
EP (1) | EP0572417A4 (en) |
JP (1) | JPH06502767A (en) |
AU (1) | AU9131591A (en) |
CA (1) | CA2096013A1 (en) |
FI (1) | FI932144A0 (en) |
HU (1) | HUT69772A (en) |
IE (1) | IE913930A1 (en) |
IL (1) | IL100040A (en) |
NO (1) | NO931709L (en) |
NZ (1) | NZ240574A (en) |
PT (1) | PT99500A (en) |
WO (1) | WO1992008800A1 (en) |
ZA (1) | ZA918965B (en) |
Families Citing this family (55)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0628076A1 (en) * | 1992-11-19 | 1994-12-14 | GINGERAS, Thomas R. | PRODUCTION OF MONOCLONAL RECOMBINANT ANTIBODIES WITHOUT THE USE OF HYBRIDOMAS BY $i(IN VITRO) SPLEEN FRAGMENT CULTURE COMBINED WITH ISOTHERMAL SELF-SUSTAINED SEQUENCE REPLICATION OF RNA |
EP0682121B1 (en) * | 1993-12-01 | 2002-08-28 | Toyo Boseki Kabushiki Kaisha | Method of amplifying and detecting target nucleic acid sequence by using thermostable enzymes |
US5705366A (en) * | 1994-09-15 | 1998-01-06 | Johnson & Johnson Clinical Diagnostics, Inc. | Coamplification of target nucleic acids using volume exclusion agent in reaction composition, test kit and test device useful therefor |
JPH08131171A (en) * | 1994-11-11 | 1996-05-28 | Asahi Chem Ind Co Ltd | Reverse transcriptase-stabilized composition |
US5763184A (en) | 1996-01-30 | 1998-06-09 | Roche Molecular Systems, Inc. | Nucleotide sequence variation in the ABO glycosyltransferase gene |
WO2000000638A2 (en) * | 1998-06-26 | 2000-01-06 | Akzo Nobel N.V. | Tagging of rna amplicons generated by transcription-based amplification |
JP2001029078A (en) * | 1999-07-16 | 2001-02-06 | Shimadzu Corp | Amplification of rna |
US7238795B2 (en) | 2000-08-03 | 2007-07-03 | Roche Molecular Systems, Inc. | Nucleic acid binding compounds containing pyrazolo[3,4-d]pyrimidine analogues of purin-2,6-diamine and their uses |
US6780588B2 (en) * | 2001-05-07 | 2004-08-24 | Applera Corporation | Methods for the reduction of stutter in microsatellite amplification |
US6841349B2 (en) | 2001-05-07 | 2005-01-11 | Applera Corporation Applied Biosystems Group | Methods for the reduction of stutter in microsatellite amplification |
US9261460B2 (en) | 2002-03-12 | 2016-02-16 | Enzo Life Sciences, Inc. | Real-time nucleic acid detection processes and compositions |
US9777312B2 (en) | 2001-06-30 | 2017-10-03 | Enzo Life Sciences, Inc. | Dual polarity analysis of nucleic acids |
US20040161741A1 (en) | 2001-06-30 | 2004-08-19 | Elazar Rabani | Novel compositions and processes for analyte detection, quantification and amplification |
DE60316660T3 (en) | 2002-01-08 | 2016-01-28 | Roche Diagnostics Gmbh | USE OF A SILICA MATERIAL IN AMPLIFICATION |
US7122314B2 (en) | 2002-01-30 | 2006-10-17 | Id Biomedical Corporation | Methods for detecting vancomycin-resistant microorganisms and compositions therefor |
US9353405B2 (en) | 2002-03-12 | 2016-05-31 | Enzo Life Sciences, Inc. | Optimized real time nucleic acid detection processes |
DE10240868A1 (en) * | 2002-09-04 | 2004-03-18 | Artus Gesellschaft für molekularbiologische Diagnostik und Entwicklung mbH | Improved procedures for the synthesis of nucleic acids |
ES2294462T5 (en) | 2003-01-29 | 2015-05-06 | Epigenomics Ag | Improved method for bisulfite treatment |
JP2004357502A (en) * | 2003-05-30 | 2004-12-24 | Olympus Corp | Method for processing information using nucleic acid molecule |
WO2006006722A1 (en) | 2004-07-13 | 2006-01-19 | Takeda Pharmaceutical Company Limited | Method of controlling cell functions |
EP1632578A1 (en) | 2004-09-03 | 2006-03-08 | Roche Diagnostics GmbH | DNA decontamination method |
GB0701253D0 (en) | 2007-01-23 | 2007-02-28 | Diagnostics For The Real World | Nucleic acid amplification and testing |
EP2185726B1 (en) | 2007-08-06 | 2014-01-08 | Orion Genomics, LLC | Novel single nucleotide polymorphisms and combinations of novel and known polymorphisms for determining the allele-specific expression of the igf2 gene |
CA2639416C (en) | 2007-09-11 | 2019-12-31 | F. Hoffmann-La Roche Ag | Diagnostic test for susceptibility to b-raf kinase inhibitors |
EP2851432B1 (en) | 2007-11-01 | 2019-01-09 | University of Iowa Research Foundation | RCA locus analysis to assess susceptibility to AMD |
EP2396429B1 (en) | 2009-02-11 | 2015-05-27 | Orion Genomics, LLC | Combinations of polymorphisms for determining allele-specific expression of igf2 |
WO2011128096A1 (en) | 2010-04-16 | 2011-10-20 | Roche Diagnostics Gmbh | Polymorphism markers for predicting response to interleukin-6 receptor-inhibiting monoclonal antibody drug treatment |
WO2011153254A2 (en) | 2010-06-04 | 2011-12-08 | Chronix Biomedical | Prostate cancer associated circulating nucleic acid biomarkers |
US20140004510A1 (en) | 2010-09-24 | 2014-01-02 | Massachusetts Eye And Ear Infirmary | Methods and compositions for prognosing and/or detecting age-related macular degeneration |
WO2012054727A1 (en) | 2010-10-22 | 2012-04-26 | Bio-Rad Laboratories, Inc. | Reverse transcriptase mixtures with improved storage stability |
MX2014002311A (en) | 2011-08-31 | 2014-08-26 | Hoffmann La Roche | Responsiveness to angiogenesis inhibitors. |
MX2014002307A (en) | 2011-08-31 | 2014-08-26 | Hoffmann La Roche | Method for predicting risk of hypertension associated with anti-angiogenesis therapy. |
CA2846630A1 (en) | 2011-09-19 | 2013-03-28 | Genentech, Inc. | Combination treatments comprising c-met antagonists and b-raf antagonists |
CA2852098C (en) | 2011-10-21 | 2023-05-02 | Chronix Biomedical | Colorectal cancer associated circulating nucleic acid biomarkers |
WO2013076029A1 (en) | 2011-11-23 | 2013-05-30 | F. Hoffmann-La Roche Ag | Responsiveness to angiogenesis inhibitors |
US9115394B2 (en) | 2011-12-22 | 2015-08-25 | Roche Molecular Systems, Inc. | Methods and reagents for reducing non-specific amplification |
EP3004388B2 (en) | 2013-05-29 | 2023-05-31 | Chronix Biomedical | Detection and quantification of donor cell-free dna in the circulation of organ transplant recipients |
EP3572093A1 (en) | 2014-03-31 | 2019-11-27 | Debiopharm International SA | Fgfr fusions |
EP3218515B1 (en) | 2014-11-10 | 2023-04-26 | F. Hoffmann-La Roche AG | Therapeutic and diagnostic methods for il-33-mediated disorders |
AU2016252998B2 (en) | 2015-04-24 | 2021-11-04 | Atila Biosystems Incorporated | Amplification with primers of limited nucleotide composition |
KR101885361B1 (en) | 2015-08-17 | 2018-08-06 | 쿠라 온콜로지, 인크. | How to treat cancer patients using parnesyl transferase inhibitor |
WO2017184968A1 (en) | 2016-04-22 | 2017-10-26 | Kura Oncology, Inc. | Methods of selecting cancer patients for treatment with farnesyltransferase inhibitors |
JP2019534290A (en) | 2016-11-03 | 2019-11-28 | クラ オンコロジー, インコーポレイテッド | Farnesyltransferase inhibitors for use in methods of treating cancer |
US9956215B1 (en) | 2017-02-21 | 2018-05-01 | Kura Oncology, Inc. | Methods of treating cancer with farnesyltransferase inhibitors |
TWI693074B (en) | 2017-02-21 | 2020-05-11 | 美商庫拉腫瘤技術股份有限公司 | Methods of treating cancer with farnesyltransferase inhibitors |
BR112020002591A2 (en) | 2017-08-07 | 2020-07-28 | Kura Oncology, Inc. | method for treating cancer |
US10806730B2 (en) | 2017-08-07 | 2020-10-20 | Kura Oncology, Inc. | Methods of treating cancer with farnesyltransferase inhibitors |
AU2019218128A1 (en) | 2018-02-09 | 2020-09-17 | Genentech, Inc. | Therapeutic and diagnostic methods for mast cell-mediated inflammatory diseases |
AU2019372141A1 (en) | 2018-11-01 | 2021-05-27 | Kura Oncology, Inc. | Methods of treating cancer with farnesyltransferase inhibitors |
US20220142983A1 (en) | 2019-03-01 | 2022-05-12 | Kura Oncology, Inc. | Methods of treating cancer with farnesyltransferase inhibitors |
CA3134825A1 (en) | 2019-03-29 | 2020-10-08 | Kura Oncology, Inc. | Methods of treating squamous cell carcinomas with farnesyltransferase inhibitors |
WO2020205387A1 (en) | 2019-04-01 | 2020-10-08 | Kura Oncology, Inc. | Methods of treating cancer with farnesyltransferase inhibitors |
US20220305001A1 (en) | 2019-05-02 | 2022-09-29 | Kura Oncology, Inc. | Methods of treating acute myeloid leukemia with farnesyltransferase inhibitors |
WO2021180858A1 (en) | 2020-03-13 | 2021-09-16 | Medimmune Limited | Therapeutic methods for the treatment of subjects with risk alelles in il33 |
WO2024015331A1 (en) | 2022-07-12 | 2024-01-18 | Genentech, Inc. | Therapeutic and diagnostic methods for multiple sclerosis |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4800159A (en) * | 1986-02-07 | 1989-01-24 | Cetus Corporation | Process for amplifying, detecting, and/or cloning nucleic acid sequences |
CA1340807C (en) * | 1988-02-24 | 1999-11-02 | Lawrence T. Malek | Nucleic acid amplification process |
ZA899593B (en) * | 1988-12-16 | 1990-09-26 | Siska Diagnostics Inc | Self-sustained,sequence replication system |
DE69028257T2 (en) * | 1989-07-11 | 1997-01-09 | Gen Probe Inc | Process for the amplification of nucleic acid sequences |
-
1991
- 1991-11-12 IL IL10004091A patent/IL100040A/en not_active IP Right Cessation
- 1991-11-12 IE IE393091A patent/IE913930A1/en not_active Application Discontinuation
- 1991-11-12 ZA ZA918965A patent/ZA918965B/en unknown
- 1991-11-13 WO PCT/US1991/008488 patent/WO1992008800A1/en not_active Application Discontinuation
- 1991-11-13 PT PT99500A patent/PT99500A/en not_active Application Discontinuation
- 1991-11-13 AU AU91315/91A patent/AU9131591A/en not_active Abandoned
- 1991-11-13 HU HU9301369A patent/HUT69772A/en unknown
- 1991-11-13 EP EP19920901557 patent/EP0572417A4/en not_active Ceased
- 1991-11-13 NZ NZ240574A patent/NZ240574A/en unknown
- 1991-11-13 JP JP4502286A patent/JPH06502767A/en active Pending
- 1991-11-13 CA CA002096013A patent/CA2096013A1/en not_active Abandoned
-
1993
- 1993-05-11 NO NO93931709A patent/NO931709L/en unknown
- 1993-05-12 FI FI932144A patent/FI932144A0/en not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
FI932144A (en) | 1993-05-12 |
NO931709D0 (en) | 1993-05-11 |
WO1992008800A1 (en) | 1992-05-29 |
EP0572417A1 (en) | 1993-12-08 |
HUT69772A (en) | 1995-09-28 |
NZ240574A (en) | 1994-10-26 |
FI932144A0 (en) | 1993-05-12 |
IL100040A (en) | 1995-12-31 |
NO931709L (en) | 1993-07-12 |
EP0572417A4 (en) | 1994-11-23 |
HU9301369D0 (en) | 1993-10-28 |
AU9131591A (en) | 1992-06-11 |
IE913930A1 (en) | 1992-06-17 |
JPH06502767A (en) | 1994-03-31 |
IL100040A0 (en) | 1992-08-18 |
PT99500A (en) | 1992-10-30 |
CA2096013A1 (en) | 1992-05-14 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
IL100040A0 (en) | Nucleic acid amplification by two-enzyme,self-sustained sequence replication | |
NZ241311A (en) | Rna sequence having trans-splicing activity, plant strains | |
NO875411D0 (en) | COMPOSITION MATERIALS, SPECIAL FOR TURBIN SHEETS. | |
IL85961A (en) | Leukemia-inhibitory factor, its purification and production, dna which encodes it, cells transformed by said dna and pharmaceutical compositions containing said factor | |
EP0262463A3 (en) | Novel aureobasidium sp. microorganisms, method for preparing erythritol with the same | |
DE3680137D1 (en) | PYRIDAZINE DERIVATIVES, THEIR PRODUCTION AND INSECTICIDES, ACARICIDES, NEMATICIDES, FUNGICIDAL COMPOSITIONS. | |
GB9009307D0 (en) | Dna,constructs,cells and plant derived therefrom | |
NO885280D0 (en) | DIGITAL, PHASE-DOWN SLFEKRETS WITH H OPPLNING. | |
DE3880984D1 (en) | EMULSION-EXPLOSIVE, EMULSIFIER. | |
AU8597791A (en) | 3-alkoxyalkanoic acid derivative, process for preparing the same and herbicide using the same | |
FI880454A0 (en) | LAOSANORDNING, SAERSKILT FOER EN LUCKA TILL EN DAMMSUGARE. | |
EG18865A (en) | Phenoxypenythioureas, phenoxyphenylisothiourreas and phenoxyphenylcarbodiimides and use thereof for controlling pests. | |
AU8419191A (en) | Dna, dna constructs, cells and plants derived therefrom | |
DE69204806D1 (en) | 1-cyanomethyl-4-carboxymethyl-3-ketopiperazines, their salts and process for their preparation. | |
IL56822A0 (en) | Pentafluorobanzyloxycarbonyl derivatives,their preparationand their use as insecticides and acaricides | |
DE3574706D1 (en) | CHARTREUSIN DERIVATIVES, THEIR SALTS, ANTITUMORAL COMPOSITIONS AND METHOD FOR THE PRODUCTION THEREOF. | |
DE3887281D1 (en) | 1,2,3,4-tetrahydro-5-nitro-pyrimidine derivatives. | |
NL193406B (en) | Fertilizer with high hardness and storage stability, as well as its preparation. | |
EP0038003A3 (en) | Antidepressant pyrrolylpiperidines | |
AU8641391A (en) | Dna, dna constructs, cells and plants derived therefrom | |
GR1002048B (en) | Phenilacetic acid derivatives, process for the preparation thereof and corresponding use. | |
NO880088D0 (en) | 2,1-benzothiazepine-2,2-dioxide-5-carboxylic acid derivatives. | |
FI893184A (en) | BEHAOLLARE FOER TRANSPORT AV LAONGSTRAECKTA FOEREMAOL, I SYNNERHET VALSAR TILL PAPPERSMASKINER. | |
EP0264748A3 (en) | Cell culture medium made from cohn supernatant fraction v | |
Bruchal | Innovations, strategies for implementation |