BR112015007606A2 - métodos e reagentes para a detecção, quantificação e serotipagem de vírus da dengue - Google Patents

métodos e reagentes para a detecção, quantificação e serotipagem de vírus da dengue

Info

Publication number
BR112015007606A2
BR112015007606A2 BR112015007606A BR112015007606A BR112015007606A2 BR 112015007606 A2 BR112015007606 A2 BR 112015007606A2 BR 112015007606 A BR112015007606 A BR 112015007606A BR 112015007606 A BR112015007606 A BR 112015007606A BR 112015007606 A2 BR112015007606 A2 BR 112015007606A2
Authority
BR
Brazil
Prior art keywords
methods
dengue virus
virus
serotyping
reagents
Prior art date
Application number
BR112015007606A
Other languages
English (en)
Inventor
A Pinsky Benjamin
Waggoner Jesse
Original Assignee
Univ Leland Stanford Junior
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Leland Stanford Junior filed Critical Univ Leland Stanford Junior
Publication of BR112015007606A2 publication Critical patent/BR112015007606A2/pt

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Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/70Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving virus or bacteriophage
    • C12Q1/701Specific hybridization probes

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Virology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)

Abstract

abstract. methods and oligonucleotide reagents for diagnosing dengue virus infection are described. in particular, the invention relates to methods for detection, quantitation, and serotyping dengue virus, including serotypes 1-4. the dengue virus can be specifically detected by these methods even in samples containing other viruses, such as west nile virus, japanese encephalitis virus, tick-born encephalitis virus, hiv, or hcv. tradução do resumo resumo "métodos e reagentes para a detecção, quantificação e serotipagem de vírus da dengue". são descritos métodos e reagentes oligonucleotídeos para diagnóstico de uma infecção por vírus da dengue. particularmente, a invenção refere-se a métodos para a detecção, a quantificação, e a serotipagem do vírus da dengue, incluindo os serotipos 1-4. o vírus da dengue pode ser especificamente detectado por estes métodos mesmo em amostras que contenham outros vírus, tais como o vírus do oeste do nilo, o vírus da encefalite japonesa, o vírus da encefalite transmitida por carrapatos, hiv ou hcv.
BR112015007606A 2012-10-04 2013-10-03 métodos e reagentes para a detecção, quantificação e serotipagem de vírus da dengue BR112015007606A2 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201261709687P 2012-10-04 2012-10-04
PCT/US2013/063238 WO2014055746A1 (en) 2012-10-04 2013-10-03 Methods and reagents for detection, quantitation, and serotyping of dengue viruses

Publications (1)

Publication Number Publication Date
BR112015007606A2 true BR112015007606A2 (pt) 2018-01-30

Family

ID=49378571

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112015007606A BR112015007606A2 (pt) 2012-10-04 2013-10-03 métodos e reagentes para a detecção, quantificação e serotipagem de vírus da dengue

Country Status (9)

Country Link
US (2) US9725774B2 (pt)
EP (1) EP2904120B1 (pt)
BR (1) BR112015007606A2 (pt)
HK (1) HK1213603A1 (pt)
IN (1) IN2015DN02893A (pt)
MX (1) MX2015004191A (pt)
MY (1) MY167603A (pt)
SG (1) SG11201502618PA (pt)
WO (1) WO2014055746A1 (pt)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2024197375A1 (pt) * 2023-03-29 2024-10-03 Fundação Oswaldo Cruz Método para determinar a presença ou ausência dos 4 sorotipos do vírus dengue em uma amostra biológica e para distinguir duas linhagens do vírus dengue 2, uso de dois pares de iniciadores e de snps, e, kit para detectar os sorotipos do vírus da dengue e para distinguir duas linhagens de denv-2

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3245306A4 (en) * 2015-01-16 2018-09-05 Takeda Vaccines, Inc. Detection of particle-contained reverse transcriptase activity
CN105441588B (zh) * 2015-12-21 2019-01-15 深圳生科原生物股份有限公司 登革热ⅰ、ⅱ、ⅲ、ⅳ型rt-pcr一步mix检测试剂盒及其检测方法
US11591660B2 (en) * 2016-01-14 2023-02-28 The Board Of Trustees Of The Leland Stanford Junior University Methods and reagents for detection of chikungunya virus or chikungunya virus and dengue virus
WO2017124054A1 (en) * 2016-01-14 2017-07-20 The Board Of Trustees Of The Leland Stanford Junior University Methods and reagents for detection of chikungunya virus and zika virus
WO2017185244A1 (zh) * 2016-04-27 2017-11-02 广东省实验动物监测所 一种快速区分四种血清型登革病毒的rt-pcr-hrm或pcr-hrm引物、试剂及方法
JP2021007351A (ja) * 2019-07-02 2021-01-28 株式会社ミルジェン デングウイルス検出試薬
CN110714096A (zh) * 2019-10-17 2020-01-21 深圳市疾病预防控制中心 一种用于同时检测4种登革热病毒分型的试剂盒
CN110894552A (zh) * 2019-11-08 2020-03-20 珠海国际旅行卫生保健中心(拱北海关口岸门诊部) 检测登革病毒的引物、探针、试剂盒和RT-iiPCR方法
EP4355908A1 (en) * 2021-06-19 2024-04-24 Obront Biotech Private Limited A method to amplify and detect target nucleic acids with very high specificity and sensitivity

Family Cites Families (41)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4174384A (en) 1975-06-30 1979-11-13 Syva Company Fluorescence quenching with immunological pairs in immunoassays
US4318846A (en) 1979-09-07 1982-03-09 Syva Company Novel ether substituted fluorescein polyamino acid compounds as fluorescers and quenchers
US4458066A (en) 1980-02-29 1984-07-03 University Patents, Inc. Process for preparing polynucleotides
US4415732A (en) 1981-03-27 1983-11-15 University Patents, Inc. Phosphoramidite compounds and processes
US4605735A (en) 1983-02-14 1986-08-12 Wakunaga Seiyaku Kabushiki Kaisha Oligonucleotide derivatives
US4683195A (en) 1986-01-30 1987-07-28 Cetus Corporation Process for amplifying, detecting, and/or-cloning nucleic acid sequences
US4683202A (en) 1985-03-28 1987-07-28 Cetus Corporation Process for amplifying nucleic acid sequences
US4757141A (en) 1985-08-26 1988-07-12 Applied Biosystems, Incorporated Amino-derivatized phosphite and phosphate linking agents, phosphoramidite precursors, and useful conjugates thereof
US4889818A (en) 1986-08-22 1989-12-26 Cetus Corporation Purified thermostable enzyme
US5322770A (en) 1989-12-22 1994-06-21 Hoffman-Laroche Inc. Reverse transcription with thermostable DNA polymerases - high temperature reverse transcription
IL86724A (en) 1987-06-19 1995-01-24 Siska Diagnostics Inc Methods and kits for amplification and testing of nucleic acid sequences
IE72468B1 (en) 1987-07-31 1997-04-09 Univ Leland Stanford Junior Selective amplification of target polynucleotide sequences
US5283174A (en) 1987-09-21 1994-02-01 Gen-Probe, Incorporated Homogenous protection assay
US5639604A (en) 1987-09-21 1997-06-17 Gen-Probe Incorporated Homogeneous protection assay
US5585481A (en) 1987-09-21 1996-12-17 Gen-Probe Incorporated Linking reagents for nucleotide probes
US6004745A (en) 1987-09-21 1999-12-21 Gen-Probe Incorporated Hybridization protection assay
US4914210A (en) 1987-10-02 1990-04-03 Cetus Corporation Oligonucleotide functionalizing reagents
US5185439A (en) 1987-10-05 1993-02-09 Gen-Probe Incorporated Acridinium ester labelling and purification of nucleotide probes
AU622426B2 (en) 1987-12-11 1992-04-09 Abbott Laboratories Assay using template-dependent nucleic acid probe reorganization
US5130238A (en) 1988-06-24 1992-07-14 Cangene Corporation Enhanced nucleic acid amplification process
US5234809A (en) 1989-03-23 1993-08-10 Akzo N.V. Process for isolating nucleic acid
CA2020958C (en) 1989-07-11 2005-01-11 Daniel L. Kacian Nucleic acid sequence amplification methods
KR100242252B1 (ko) 1989-07-11 2000-03-02 다니엘 엘. 캐시앙 핵산서열의 증폭방법
ATE137269T1 (de) 1990-01-26 1996-05-15 Abbott Lab Verbessertes verfahren zur amplifikation von nuklein säurezielsequenz, einsetzbar für die polymerase und ligasekettenreaktion
CA2135073C (en) 1992-05-06 2002-11-19 Daniel L. Kacian Nucleic acid sequence amplification method, composition and kit
US5538848A (en) 1994-11-16 1996-07-23 Applied Biosystems Division, Perkin-Elmer Corp. Method for detecting nucleic acid amplification using self-quenching fluorescence probe
US6720166B2 (en) 1994-02-14 2004-04-13 Abbott Laboratories Non-a, non-b, non-c, non-c, non-d, non-e hepatitis reagents and methods for their use
US5648211A (en) 1994-04-18 1997-07-15 Becton, Dickinson And Company Strand displacement amplification using thermophilic enzymes
US5556771A (en) 1995-02-10 1996-09-17 Gen-Probe Incorporated Stabilized compositions of reverse transcriptase and RNA polymerase for nucleic acid amplification
US6312894B1 (en) 1995-04-03 2001-11-06 Epoch Pharmaceuticals, Inc. Hybridization and mismatch discrimination using oligonucleotides conjugated to minor groove binders
US5801155A (en) 1995-04-03 1998-09-01 Epoch Pharmaceuticals, Inc. Covalently linked oligonucleotide minor grove binder conjugates
JP3108105B2 (ja) 1995-08-21 2000-11-13 三光純薬株式会社 共沈剤及び核酸の抽出方法
US6849431B2 (en) 1997-07-25 2005-02-01 Ryoji Tamura Non-B, non-C, non-G hepatitis virus gene, polynucleotide, polypeptide, virus particle, method for isolating virus particle, and method for detecting virus
AU2001257454A1 (en) 2000-04-28 2001-11-12 Quantum Dot Corporation Methods and compositions for polynucleotide analysis using generic capture sequences
DE60141087D1 (de) 2000-06-26 2010-03-04 Nugen Technologies Inc Methoden und zusammensetzungen zur auf transkription basierenden vervielfältigung von nukleinsäuren
CU23578A1 (es) * 2005-09-16 2010-09-30 Ct Ingenieria Genetica Biotech Proteína de la cápsida del virus dengue inductora de respuesta protectora y composición vacunal
EP1986686A4 (en) * 2006-02-13 2010-08-11 Integral Molecular Inc VIRUS REPORTER OF DENGUE AND METHODS OF MAKING AND USING SAME
US20100211327A1 (en) * 2009-02-03 2010-08-19 Prosetta Bioconformatics, Inc. Methods and Systems for Viral Diagnosis
WO2011026139A1 (en) * 2009-08-31 2011-03-03 Gen-Probe Incorporated Dengue virus assay
WO2012153153A1 (en) * 2011-05-11 2012-11-15 Diagon Kft. Procedure for rapid determination of viruses using nucleic acid-based molecular diagnostics, and a kit for this purpose
GB201119028D0 (en) * 2011-11-04 2011-12-14 Epistem Ltd Dengue assay

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2024197375A1 (pt) * 2023-03-29 2024-10-03 Fundação Oswaldo Cruz Método para determinar a presença ou ausência dos 4 sorotipos do vírus dengue em uma amostra biológica e para distinguir duas linhagens do vírus dengue 2, uso de dois pares de iniciadores e de snps, e, kit para detectar os sorotipos do vírus da dengue e para distinguir duas linhagens de denv-2

Also Published As

Publication number Publication date
US10093994B2 (en) 2018-10-09
MX2015004191A (es) 2016-04-04
US20170306425A1 (en) 2017-10-26
HK1213603A1 (zh) 2016-07-08
EP2904120B1 (en) 2018-01-10
MY167603A (en) 2018-09-20
EP2904120A1 (en) 2015-08-12
US20150225802A1 (en) 2015-08-13
WO2014055746A1 (en) 2014-04-10
US9725774B2 (en) 2017-08-08
SG11201502618PA (en) 2015-05-28
IN2015DN02893A (pt) 2015-09-11

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Legal Events

Date Code Title Description
B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B25G Requested change of headquarter approved

Owner name: THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIO

B06I Publication of requirement cancelled [chapter 6.9 patent gazette]

Free format text: ANULADA A PUBLICACAO CODIGO 6.6.1 NA RPI NO 2462 DE 13/03/2018 POR TER SIDO INDEVIDA.

B07A Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
B09B Patent application refused [chapter 9.2 patent gazette]
B12B Appeal against refusal [chapter 12.2 patent gazette]
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE A 11A ANUIDADE.