DK1317440T3 - Fremgangsmåde til fremstilling af 2- (6-substitueret 1,3-dioxan-4yl) eddikesyrederivater - Google Patents
Fremgangsmåde til fremstilling af 2- (6-substitueret 1,3-dioxan-4yl) eddikesyrederivaterInfo
- Publication number
- DK1317440T3 DK1317440T3 DK01953373T DK01953373T DK1317440T3 DK 1317440 T3 DK1317440 T3 DK 1317440T3 DK 01953373 T DK01953373 T DK 01953373T DK 01953373 T DK01953373 T DK 01953373T DK 1317440 T3 DK1317440 T3 DK 1317440T3
- Authority
- DK
- Denmark
- Prior art keywords
- substituted
- formula
- dioxane
- preparation
- acetic acid
- Prior art date
Links
- -1 2- (6-substituted 1,3-dioxane-4yl) acetic acid Chemical class 0.000 title abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 2
- XYICPZVNNCLGCU-UHFFFAOYSA-N 2-[6-(hydroxymethyl)-1,3-dioxan-4-yl]acetic acid Chemical compound OCC1CC(CC(O)=O)OCO1 XYICPZVNNCLGCU-UHFFFAOYSA-N 0.000 abstract 1
- 229940121710 HMGCoA reductase inhibitor Drugs 0.000 abstract 1
- 238000006359 acetalization reaction Methods 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 239000003377 acid catalyst Substances 0.000 abstract 1
- 150000007513 acids Chemical class 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- QGZKDVFQNNGYKY-UHFFFAOYSA-O ammonium group Chemical group [NH4+] QGZKDVFQNNGYKY-UHFFFAOYSA-O 0.000 abstract 1
- 125000004432 carbon atom Chemical group C* 0.000 abstract 1
- 238000006243 chemical reaction Methods 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 1
- 239000001257 hydrogen Substances 0.000 abstract 1
- 125000004435 hydrogen atom Chemical class [H]* 0.000 abstract 1
- 239000002471 hydroxymethylglutaryl coenzyme A reductase inhibitor Substances 0.000 abstract 1
- 239000002184 metal Substances 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 125000000999 tert-butyl group Chemical group [H]C([H])([H])C(*)(C([H])([H])[H])C([H])([H])[H] 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
- C07D309/16—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D309/28—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D309/30—Oxygen atoms, e.g. delta-lactones
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D319/00—Heterocyclic compounds containing six-membered rings having two oxygen atoms as the only ring hetero atoms
- C07D319/04—1,3-Dioxanes; Hydrogenated 1,3-dioxanes
- C07D319/06—1,3-Dioxanes; Hydrogenated 1,3-dioxanes not condensed with other rings
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T428/00—Stock material or miscellaneous articles
- Y10T428/29—Coated or structually defined flake, particle, cell, strand, strand portion, rod, filament, macroscopic fiber or mass thereof
- Y10T428/2982—Particulate matter [e.g., sphere, flake, etc.]
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Compounds That Contain Two Or More Ring Oxygen Atoms (AREA)
- Plural Heterocyclic Compounds (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Catalysts (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| NL1015744A NL1015744C2 (nl) | 2000-07-19 | 2000-07-19 | Werkwijze voor de bereiding van 2-(6-gesubstitueerde-1,3-dioxan-4-yl) azijnzuurderivaten. |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK1317440T3 true DK1317440T3 (da) | 2007-01-08 |
Family
ID=19771761
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK01953373T DK1317440T3 (da) | 2000-07-19 | 2001-07-12 | Fremgangsmåde til fremstilling af 2- (6-substitueret 1,3-dioxan-4yl) eddikesyrederivater |
Country Status (29)
| Country | Link |
|---|---|
| US (4) | US6870059B2 (cs) |
| EP (2) | EP1700854B1 (cs) |
| JP (2) | JP5006499B2 (cs) |
| KR (3) | KR100865016B1 (cs) |
| CN (3) | CN101081842B (cs) |
| AT (1) | ATE340790T1 (cs) |
| AU (2) | AU2001275830B2 (cs) |
| BR (1) | BR0112535A (cs) |
| CA (1) | CA2415963C (cs) |
| CY (1) | CY1105881T1 (cs) |
| CZ (1) | CZ302718B6 (cs) |
| DE (1) | DE60123444T2 (cs) |
| DK (1) | DK1317440T3 (cs) |
| EE (1) | EE200300024A (cs) |
| ES (2) | ES2272506T3 (cs) |
| HU (1) | HUP0303166A3 (cs) |
| IL (3) | IL153980A0 (cs) |
| IS (2) | IS2386B (cs) |
| MX (1) | MXPA03000498A (cs) |
| NL (1) | NL1015744C2 (cs) |
| NO (1) | NO328935B1 (cs) |
| NZ (1) | NZ523703A (cs) |
| PL (1) | PL207115B1 (cs) |
| PT (1) | PT1317440E (cs) |
| RU (1) | RU2266903C2 (cs) |
| SK (2) | SK287756B6 (cs) |
| UA (1) | UA77944C2 (cs) |
| WO (1) | WO2002006266A1 (cs) |
| ZA (1) | ZA200300478B (cs) |
Families Citing this family (32)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB0011120D0 (en) | 2000-05-09 | 2000-06-28 | Avecia Ltd | Process |
| NL1015744C2 (nl) | 2000-07-19 | 2002-01-22 | Dsm Nv | Werkwijze voor de bereiding van 2-(6-gesubstitueerde-1,3-dioxan-4-yl) azijnzuurderivaten. |
| IL159741A0 (en) * | 2001-07-13 | 2004-06-20 | Astrazeneca Uk Ltd | Preparation of aminopyrimidine compounds |
| EP1323717A1 (en) | 2001-12-27 | 2003-07-02 | Dsm N.V. | Process for the preparation of 2-(6-Substituted-1,3-Dioxane-4-yL) acetic acid derivatives |
| EP1375493A1 (en) * | 2002-06-17 | 2004-01-02 | Dsm N.V. | Process for the preparation of an dioxane acetic acid ester |
| GB0218781D0 (en) * | 2002-08-13 | 2002-09-18 | Astrazeneca Ab | Chemical process |
| JP2006512086A (ja) | 2002-09-20 | 2006-04-13 | ダイヴァーサ コーポレイション | スタチンおよびスタチン中間体の合成のための酵素化学的方法 |
| US9740817B1 (en) | 2002-10-18 | 2017-08-22 | Dennis Sunga Fernandez | Apparatus for biological sensing and alerting of pharmaco-genomic mutation |
| NZ540722A (en) * | 2002-12-16 | 2008-03-28 | Astrazeneca Uk Ltd | Process for the preparation of pyrimidine compounds and intermediates thereof |
| KR20060011984A (ko) * | 2003-05-02 | 2006-02-06 | 디에스엠 아이피 어셋츠 비.브이. | (4-하이드록시-6-옥소-테트라하이드로피란-2-일)아세토니트릴 및 이의 유도체의 제조방법 |
| GB0312896D0 (en) * | 2003-06-05 | 2003-07-09 | Astrazeneca Ab | Chemical process |
| US8346482B2 (en) | 2003-08-22 | 2013-01-01 | Fernandez Dennis S | Integrated biosensor and simulation system for diagnosis and therapy |
| UY28501A1 (es) * | 2003-09-10 | 2005-04-29 | Astrazeneca Uk Ltd | Compuestos químicos |
| GB0321827D0 (en) * | 2003-09-18 | 2003-10-15 | Astrazeneca Uk Ltd | Chemical compounds |
| GB0324791D0 (en) * | 2003-10-24 | 2003-11-26 | Astrazeneca Ab | Chemical process |
| DE10352659B4 (de) * | 2003-11-11 | 2007-09-13 | Ratiopharm Gmbh | Verfahren zur Herstellung von Statinen und Tetrahydropyranonderivate zur Verwendung in dem Verfahren |
| GB0428328D0 (en) * | 2004-12-24 | 2005-02-02 | Astrazeneca Uk Ltd | Chemical process |
| GB0514078D0 (en) * | 2005-07-08 | 2005-08-17 | Astrazeneca Uk Ltd | Chemical process |
| US7264743B2 (en) * | 2006-01-23 | 2007-09-04 | Lam Research Corporation | Fin structure formation |
| TW200831469A (en) * | 2006-12-01 | 2008-08-01 | Astrazeneca Uk Ltd | Chemical process |
| EP2419407B1 (en) * | 2009-04-15 | 2012-11-14 | Pharmathen S.A. | Improved process for the preparation of fluvastatin and salts thereof |
| GB2482525A (en) * | 2010-08-05 | 2012-02-08 | Phoenix Chemicals Ltd | A process for the production of acyloxymethyldioxanylacetic derivatives |
| MX2013002674A (es) | 2010-09-09 | 2013-06-13 | Dsm Sinochem Pharm Bv | Sales de esteres de acido 7-amino-3,5-dihidroxiheptanoico. |
| WO2012034958A1 (en) | 2010-09-16 | 2012-03-22 | Dsm Sinochem Pharmaceuticals Netherlands B.V. | Esters of hexanoic acids as intermediates for the preparation of atorvastatin |
| PL2665722T3 (pl) | 2011-01-18 | 2017-03-31 | Dsm Sinochem Pharmaceuticals Netherlands B.V. | Sposób otrzymywania diolosulfonów |
| SI2665723T1 (sl) | 2011-01-18 | 2015-11-30 | Dsm Sinochem Pharmaceuticals Netherlands B.V. | Postopek priprave statinov v prisotnosti baze |
| HUE027729T2 (en) | 2011-01-18 | 2016-10-28 | Dsm Sinochem Pharm Nl Bv | Methyl tetrazole sulphides and sulfones |
| MX363563B (es) * | 2011-12-09 | 2019-03-27 | Dsm Sinochem Pharm Nl Bv | Proceso para la preparación de un tioprecursor de estatinas. |
| MX359424B (es) | 2011-12-09 | 2018-09-12 | Dsm Sinochem Pharm Nl Bv | Proceso para la preparación de un precursor de estatina. |
| JP6065862B2 (ja) * | 2013-04-10 | 2017-01-25 | 信越化学工業株式会社 | パターン形成方法、レジスト組成物、高分子化合物及び単量体 |
| WO2014203045A1 (en) | 2013-06-20 | 2014-12-24 | Lupin Limited | A novel, green and cost effective process for synthesis of tert-butyl (3r,5s)-6-oxo-3,5-dihydroxy-3,5-o-isopropylidene-hexanoate |
| CN105624127B (zh) * | 2014-10-28 | 2019-07-26 | 上海弈柯莱生物医药科技有限公司 | 一种葡萄糖脱氢酶及其在合成他汀类药物中间体中的应用 |
Family Cites Families (47)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US544390A (en) * | 1895-08-13 | Chimney-cowl | ||
| GB885516A (en) | 1958-01-16 | 1961-12-28 | Arthur Henry Clarkson | Higher fatty acid esters of dextran |
| US3325466A (en) | 1961-01-11 | 1967-06-13 | American Cyanamid Co | Tertiary butyl group as a carboxyl protecting group in the synthesis of peptides |
| US3992432A (en) | 1967-04-05 | 1976-11-16 | Continental Oil Company | Phase transfer catalysis of heterogeneous reactions by quaternary salts |
| DE3929913A1 (de) * | 1989-09-08 | 1991-04-04 | Hoechst Ag | 4-hydroxytetrahydropyran-2-one sowie die entsprechenden dihydroxycarbonsaeurederivate, salze und ester, verfahren zu ihrer herstellung, ihre verwendung als arzneimittel, pharmazeutische praeparate sowie vorprodukte |
| GB9005966D0 (en) | 1990-03-16 | 1990-05-09 | May & Baker Ltd | New compositions of matter |
| CA2048716A1 (en) * | 1990-08-17 | 1992-02-18 | William B. Mattingly, Iii | Absorbent articles with integral release system and methods of making same |
| JP3097143B2 (ja) | 1991-02-21 | 2000-10-10 | チッソ株式会社 | 生理活性物質合成用光学活性化合物の製造法および光学活性中間体化合物 |
| US5292891A (en) * | 1991-02-21 | 1994-03-08 | Chisso Corporation | Optically active 2,2-dimethyl-1,3-dioxin-4-ones and method for preparing same and method for preparing optically active compound for synthesis of physiologically active substance and optically active intermediate compound |
| JP3333197B2 (ja) * | 1991-09-20 | 2002-10-07 | アヴェシア リミテッド | ピラノン |
| WO1993008823A1 (en) * | 1991-11-06 | 1993-05-13 | Tanabe Seiyaku Co., Ltd. | Guanidinyl and related cell adhesion modulation compounds |
| US5278313A (en) | 1992-03-27 | 1994-01-11 | E. R. Squibb & Sons, Inc. | Process for the preparation of 1,3-dioxane derivatives useful in the preparation of HMG-COA reductase inhibitors |
| FR2696460B1 (fr) * | 1992-10-05 | 1994-11-25 | Rhone Poulenc Rorer Sa | Procédé de préparation de dérivés du taxane. |
| US5449793A (en) * | 1993-06-04 | 1995-09-12 | Chisso Corporation | Process for producing an optically active 1,5-disubstituted-2,4-O-isopropylidene-2,4-dihydroxypentane |
| US5795749A (en) | 1995-04-05 | 1998-08-18 | The Scripps Research Institution | Use of 2-deoxyribose-5-phosphate aldolase to prepare 2-deoxyfucose, analogues and derivatives |
| GB9523924D0 (en) | 1995-11-23 | 1996-01-24 | Zeneca Ltd | Production of optically active 2-substituted tetrahydropyran-4-ones |
| FR2741620B1 (fr) * | 1995-11-28 | 1997-12-26 | Oreal | Procede de preparation de composes a groupement beta-hydroxy -delta-lactone analogues de la (+) compactine et de la (+) mevinoline |
| US6278001B1 (en) | 1995-11-28 | 2001-08-21 | L'oréal | Method for preparing (+) compactin and (+) mevinolin analog compounds having a β-hydroxy-δ-lactone grouping |
| US6344569B1 (en) | 1998-04-30 | 2002-02-05 | Kaneka Corporation | Process for producing 6-cyanomethyl-1,3-dioxane-4-acetic acid derivatives |
| CN100376682C (zh) * | 1998-08-05 | 2008-03-26 | 钟渊化学工业株式会社 | 制备光学活性的2-[6-（羟甲基）-1，3-二噁烷-4-基]乙酸衍生物的方法 |
| AU1683000A (en) | 1998-12-10 | 2000-06-26 | Kaneka Corporation | Process for producing simvastatin |
| GB9903472D0 (en) | 1999-02-17 | 1999-04-07 | Zeneca Ltd | Chemical process |
| HU227840B1 (en) | 1999-05-06 | 2012-05-02 | Egis Gyogyszergyar Nyilvanosan M Kod Ruszvunytarsasag | Intermediates of atorvastatin synthesis and process for producing them |
| ES2219345T3 (es) | 1999-06-04 | 2004-12-01 | Kaneka Corporation | Procedimiento para la preparacion de derivados del acido 5-hidroxi-3-oxopentanoico. |
| WO2001072706A1 (en) * | 2000-03-28 | 2001-10-04 | Biocon India Limited | Synthesis of [r-(r*,r*)]-2-(4-fluorophenyl)-beta,delta-dihydroxy-5-(1-methylethyl)-3-phenyl-4-[(phenylamino)carbonyl]-1h-pyrrole-1-heptanoic acid hemi calcium salt (atorvastatin) |
| GB0011120D0 (en) | 2000-05-09 | 2000-06-28 | Avecia Ltd | Process |
| AU6269201A (en) * | 2000-06-05 | 2001-12-17 | Kaneka Corporation | Process for preparing optically active 2-(6-(hydroxy-methyl)-1,3-dioxan-4-yl)acetic acid derivatives |
| NL1015744C2 (nl) | 2000-07-19 | 2002-01-22 | Dsm Nv | Werkwijze voor de bereiding van 2-(6-gesubstitueerde-1,3-dioxan-4-yl) azijnzuurderivaten. |
| IL159741A0 (en) | 2001-07-13 | 2004-06-20 | Astrazeneca Uk Ltd | Preparation of aminopyrimidine compounds |
| EP1323717A1 (en) | 2001-12-27 | 2003-07-02 | Dsm N.V. | Process for the preparation of 2-(6-Substituted-1,3-Dioxane-4-yL) acetic acid derivatives |
| HRP20040888B1 (en) | 2002-02-25 | 2012-12-31 | Biocon Ltd | Novel boronate esters |
| KR100511533B1 (ko) | 2002-04-09 | 2005-08-31 | 임광민 | 키랄 중간체, 그의 제조방법 및 그를 이용한 HMG-CoA환원저해제의 제조방법 |
| EP1375493A1 (en) | 2002-06-17 | 2004-01-02 | Dsm N.V. | Process for the preparation of an dioxane acetic acid ester |
| GB0218781D0 (en) | 2002-08-13 | 2002-09-18 | Astrazeneca Ab | Chemical process |
| NZ540722A (en) | 2002-12-16 | 2008-03-28 | Astrazeneca Uk Ltd | Process for the preparation of pyrimidine compounds and intermediates thereof |
| WO2004103977A2 (en) | 2003-05-21 | 2004-12-02 | Ciba Specialty Chemicals Holding Inc. | Process for the preparation of pyrimidine derivatives |
| GB0312896D0 (en) | 2003-06-05 | 2003-07-09 | Astrazeneca Ab | Chemical process |
| WO2004113314A1 (en) | 2003-06-23 | 2004-12-29 | Biocon Limited | Novel boronate esters |
| UY28501A1 (es) | 2003-09-10 | 2005-04-29 | Astrazeneca Uk Ltd | Compuestos químicos |
| GB0321827D0 (en) | 2003-09-18 | 2003-10-15 | Astrazeneca Uk Ltd | Chemical compounds |
| GB0324791D0 (en) | 2003-10-24 | 2003-11-26 | Astrazeneca Ab | Chemical process |
| JP4037900B2 (ja) | 2003-12-24 | 2008-01-23 | テバ ファーマシューティカル インダストリーズ リミティド | Ａｎｔｉに対するｓｙｎ比率が高いスタチンの製造方法 |
| JP4266879B2 (ja) | 2004-05-12 | 2009-05-20 | 大阪瓦斯株式会社 | ガス化炉及び複合リサイクル装置 |
| US7161004B2 (en) | 2004-06-21 | 2007-01-09 | Dr. Reddy's Laboratories Limited | Processes to produce intermediates for rosuvastatin |
| GB0428328D0 (en) | 2004-12-24 | 2005-02-02 | Astrazeneca Uk Ltd | Chemical process |
| GB0514078D0 (en) | 2005-07-08 | 2005-08-17 | Astrazeneca Uk Ltd | Chemical process |
| TW200831469A (en) | 2006-12-01 | 2008-08-01 | Astrazeneca Uk Ltd | Chemical process |
-
2000
- 2000-07-19 NL NL1015744A patent/NL1015744C2/nl not_active IP Right Cessation
-
2001
- 2001-07-12 CZ CZ20030163A patent/CZ302718B6/cs not_active IP Right Cessation
- 2001-07-12 EP EP06010837A patent/EP1700854B1/en not_active Expired - Lifetime
- 2001-07-12 SK SK123-2010A patent/SK287756B6/sk not_active IP Right Cessation
- 2001-07-12 PT PT01953373T patent/PT1317440E/pt unknown
- 2001-07-12 NZ NZ523703A patent/NZ523703A/en not_active IP Right Cessation
- 2001-07-12 AU AU2001275830A patent/AU2001275830B2/en not_active Ceased
- 2001-07-12 ES ES01953373T patent/ES2272506T3/es not_active Expired - Lifetime
- 2001-07-12 PL PL359332A patent/PL207115B1/pl not_active IP Right Cessation
- 2001-07-12 AU AU7583001A patent/AU7583001A/xx active Pending
- 2001-07-12 RU RU2003104825/04A patent/RU2266903C2/ru not_active IP Right Cessation
- 2001-07-12 MX MXPA03000498A patent/MXPA03000498A/es active IP Right Grant
- 2001-07-12 IL IL15398001A patent/IL153980A0/xx active IP Right Grant
- 2001-07-12 CN CN2007101118797A patent/CN101081842B/zh not_active Expired - Lifetime
- 2001-07-12 CN CNB2005100657442A patent/CN100378091C/zh not_active Expired - Lifetime
- 2001-07-12 EP EP01953373A patent/EP1317440B1/en not_active Expired - Lifetime
- 2001-07-12 CA CA002415963A patent/CA2415963C/en not_active Expired - Fee Related
- 2001-07-12 KR KR1020027017684A patent/KR100865016B1/ko not_active Expired - Fee Related
- 2001-07-12 WO PCT/NL2001/000535 patent/WO2002006266A1/en not_active Ceased
- 2001-07-12 CN CN01812999A patent/CN1443183A/zh not_active Withdrawn
- 2001-07-12 ES ES06010837T patent/ES2387313T3/es not_active Expired - Lifetime
- 2001-07-12 SK SK35-2003A patent/SK287755B6/sk not_active IP Right Cessation
- 2001-07-12 DE DE60123444T patent/DE60123444T2/de not_active Expired - Lifetime
- 2001-07-12 KR KR1020077027471A patent/KR20070121063A/ko not_active Ceased
- 2001-07-12 BR BR0112535-4A patent/BR0112535A/pt not_active IP Right Cessation
- 2001-07-12 HU HU0303166A patent/HUP0303166A3/hu unknown
- 2001-07-12 DK DK01953373T patent/DK1317440T3/da active
- 2001-07-12 JP JP2002512170A patent/JP5006499B2/ja not_active Expired - Lifetime
- 2001-07-12 KR KR1020087019878A patent/KR20080078925A/ko not_active Ceased
- 2001-07-12 EE EEP200300024A patent/EE200300024A/xx unknown
- 2001-07-12 US US10/333,351 patent/US6870059B2/en not_active Expired - Lifetime
- 2001-07-12 AT AT01953373T patent/ATE340790T1/de active
- 2001-12-07 UA UA2003010456A patent/UA77944C2/uk unknown
-
2003
- 2003-01-03 NO NO20030025A patent/NO328935B1/no not_active IP Right Cessation
- 2003-01-15 IS IS6680A patent/IS2386B/is unknown
- 2003-01-16 IL IL153980A patent/IL153980A/en not_active IP Right Cessation
- 2003-01-17 ZA ZA200300478A patent/ZA200300478B/en unknown
-
2005
- 2005-02-07 US US11/053,090 patent/US7642363B2/en not_active Expired - Lifetime
-
2006
- 2006-08-31 IL IL177824A patent/IL177824A0/en not_active IP Right Cessation
- 2006-12-21 CY CY20061101848T patent/CY1105881T1/el unknown
-
2007
- 2007-11-15 IS IS8690A patent/IS8690A/is unknown
-
2009
- 2009-11-24 US US12/625,156 patent/US7989643B2/en not_active Expired - Fee Related
-
2011
- 2011-06-22 US US13/166,607 patent/US20110251406A1/en not_active Abandoned
- 2011-12-06 JP JP2011267056A patent/JP2012111757A/ja active Pending
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| DK1317440T3 (da) | Fremgangsmåde til fremstilling af 2- (6-substitueret 1,3-dioxan-4yl) eddikesyrederivater | |
| DE602004019329D1 (de) | Verfahren zur herstellung substituierter nikotinsäureester | |
| DK1515962T3 (da) | Fremgangsmåde til fremstilling af dioxaneddikesyreestere | |
| DK1877384T3 (da) | Fremgangsmåde til fremstilling af eventuelt 2-substituerede 1,6-dihydro-6-oxo-4-pyrimidincarboxylsyrer | |
| DK219288D0 (da) | Fremgangsmaade til reduktion af karboxylsyreestere | |
| ES8200681A1 (es) | Procedimiento para la preparacion de derivados de 5,11-dihi-dro-6h-pirido(2,3-b)(1,4)-benzodiazepin-6-ona | |
| IL131177A (en) | Process for the preparation of nicotinic acids and esters | |
| DE50009219D1 (de) | Verfahren zur herstellung von estern | |
| IS6636A (is) | Hringlaga ketonar og notkun þeirra í smíði amínósýra | |
| CA2379981A1 (en) | Process for producing isocoumarins and intermediates for the same | |
| PL378179A1 (pl) | Sposób wytwarzania podstawionych pochodnych imidazolu i związki pośrednie stosowane w sposobie | |
| EP1375492A4 (en) | PROCESS FOR PREPARING (DIOXOLENONE-4-YL) METHYL ESTERS DERIVATIVES | |
| PL326563A1 (en) | Method of obtaining derivatives of methoxyiminophenyglyoxalic acid | |
| RU97118593A (ru) | ПРОИЗВОДНЫЕ 1-[ω-(3,4-ДИГИДРО-2-НАФТАЛИНИЛ)АЛКИЛ] ЦИКЛИЧЕСКОГО АМИНА, СПОСОБ ИХ ПОЛУЧЕНИЯ И СОДЕРЖАЩАЯ ИХ ФАРМАЦЕВТИЧЕСКАЯ КОМПОЗИЦИЯ | |
| DK1257523T3 (da) | Fremgangsmåde til fremstilling af 3-aminoalkansyreestere | |
| HK1047080A1 (zh) | 通过阿而法-含氯环氧酯制备酸的方法 | |
| SE8302158D0 (sv) | Verfahren zur herstellung von 1-alkyl-5-aroyl-pyrrol-2-essigseure-derivaten | |
| KR970010737A (ko) | 2-(4-아세틸아미노벤조일아미노)벤즈아미드 유도체, 그 제조방법 및 그를 함유하는 진통제 |