CN1443183A - 2-(6-取代的1,3-二噁烷-4-基)乙酸衍生物的制备方法 - Google Patents
2-(6-取代的1,3-二噁烷-4-基)乙酸衍生物的制备方法 Download PDFInfo
- Publication number
- CN1443183A CN1443183A CN01812999A CN01812999A CN1443183A CN 1443183 A CN1443183 A CN 1443183A CN 01812999 A CN01812999 A CN 01812999A CN 01812999 A CN01812999 A CN 01812999A CN 1443183 A CN1443183 A CN 1443183A
- Authority
- CN
- China
- Prior art keywords
- formula
- compound
- diox
- replacement
- acetogenin
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
- C07D309/16—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D309/28—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D309/30—Oxygen atoms, e.g. delta-lactones
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D319/00—Heterocyclic compounds containing six-membered rings having two oxygen atoms as the only ring hetero atoms
- C07D319/04—1,3-Dioxanes; Hydrogenated 1,3-dioxanes
- C07D319/06—1,3-Dioxanes; Hydrogenated 1,3-dioxanes not condensed with other rings
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T428/00—Stock material or miscellaneous articles
- Y10T428/29—Coated or structually defined flake, particle, cell, strand, strand portion, rod, filament, macroscopic fiber or mass thereof
- Y10T428/2982—Particulate matter [e.g., sphere, flake, etc.]
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Compounds That Contain Two Or More Ring Oxygen Atoms (AREA)
- Plural Heterocyclic Compounds (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Catalysts (AREA)
Abstract
Description
Claims (15)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
NL1015744 | 2000-07-19 | ||
NL1015744A NL1015744C2 (nl) | 2000-07-19 | 2000-07-19 | Werkwijze voor de bereiding van 2-(6-gesubstitueerde-1,3-dioxan-4-yl) azijnzuurderivaten. |
Related Child Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CNB2005100657442A Division CN100378091C (zh) | 2000-07-19 | 2001-07-12 | 2-(6-取代的1,3-二烷-4-基)乙酸衍生物的制备方法 |
CN2007101118797A Division CN101081842B (zh) | 2000-07-19 | 2001-07-12 | 2-(6-取代的1,3-二噁烷-4-基)乙酸衍生物的制备方法 |
Publications (1)
Publication Number | Publication Date |
---|---|
CN1443183A true CN1443183A (zh) | 2003-09-17 |
Family
ID=19771761
Family Applications (3)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CN2007101118797A Expired - Lifetime CN101081842B (zh) | 2000-07-19 | 2001-07-12 | 2-(6-取代的1,3-二噁烷-4-基)乙酸衍生物的制备方法 |
CNB2005100657442A Expired - Lifetime CN100378091C (zh) | 2000-07-19 | 2001-07-12 | 2-(6-取代的1,3-二烷-4-基)乙酸衍生物的制备方法 |
CN01812999A Withdrawn CN1443183A (zh) | 2000-07-19 | 2001-07-12 | 2-(6-取代的1,3-二噁烷-4-基)乙酸衍生物的制备方法 |
Family Applications Before (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CN2007101118797A Expired - Lifetime CN101081842B (zh) | 2000-07-19 | 2001-07-12 | 2-(6-取代的1,3-二噁烷-4-基)乙酸衍生物的制备方法 |
CNB2005100657442A Expired - Lifetime CN100378091C (zh) | 2000-07-19 | 2001-07-12 | 2-(6-取代的1,3-二烷-4-基)乙酸衍生物的制备方法 |
Country Status (30)
Country | Link |
---|---|
US (4) | US6870059B2 (zh) |
EP (2) | EP1700854B1 (zh) |
JP (2) | JP5006499B2 (zh) |
KR (3) | KR100865016B1 (zh) |
CN (3) | CN101081842B (zh) |
AT (1) | ATE340790T1 (zh) |
AU (2) | AU2001275830B2 (zh) |
BR (1) | BR0112535A (zh) |
CA (1) | CA2415963C (zh) |
CY (1) | CY1105881T1 (zh) |
CZ (1) | CZ302718B6 (zh) |
DE (1) | DE60123444T2 (zh) |
DK (1) | DK1317440T3 (zh) |
EE (1) | EE200300024A (zh) |
ES (2) | ES2272506T3 (zh) |
HK (1) | HK1097260A1 (zh) |
HU (1) | HUP0303166A3 (zh) |
IL (3) | IL153980A0 (zh) |
IS (2) | IS2386B (zh) |
MX (1) | MXPA03000498A (zh) |
NL (1) | NL1015744C2 (zh) |
NO (1) | NO328935B1 (zh) |
NZ (1) | NZ523703A (zh) |
PL (1) | PL207115B1 (zh) |
PT (1) | PT1317440E (zh) |
RU (1) | RU2266903C2 (zh) |
SK (2) | SK287755B6 (zh) |
UA (1) | UA77944C2 (zh) |
WO (1) | WO2002006266A1 (zh) |
ZA (1) | ZA200300478B (zh) |
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN103974946A (zh) * | 2011-12-09 | 2014-08-06 | 中化帝斯曼制药有限公司荷兰公司 | 制备他汀前体的方法 |
CN103987705A (zh) * | 2011-12-09 | 2014-08-13 | 中化帝斯曼制药有限公司荷兰公司 | 制备他汀含硫前体的方法 |
Families Citing this family (30)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB0011120D0 (en) | 2000-05-09 | 2000-06-28 | Avecia Ltd | Process |
NL1015744C2 (nl) | 2000-07-19 | 2002-01-22 | Dsm Nv | Werkwijze voor de bereiding van 2-(6-gesubstitueerde-1,3-dioxan-4-yl) azijnzuurderivaten. |
CN100349877C (zh) | 2001-07-13 | 2007-11-21 | 阿斯特拉曾尼卡英国有限公司 | 氨基嘧啶化合物的制备方法 |
EP1323717A1 (en) * | 2001-12-27 | 2003-07-02 | Dsm N.V. | Process for the preparation of 2-(6-Substituted-1,3-Dioxane-4-yL) acetic acid derivatives |
EP1375493A1 (en) * | 2002-06-17 | 2004-01-02 | Dsm N.V. | Process for the preparation of an dioxane acetic acid ester |
GB0218781D0 (en) | 2002-08-13 | 2002-09-18 | Astrazeneca Ab | Chemical process |
US7414119B2 (en) | 2002-09-20 | 2008-08-19 | Verenium Corporation | Aldolases, nucleic acids encoding them and methods for making and using them |
US9740817B1 (en) | 2002-10-18 | 2017-08-22 | Dennis Sunga Fernandez | Apparatus for biological sensing and alerting of pharmaco-genomic mutation |
DE60330050D1 (de) * | 2002-12-16 | 2009-12-24 | Astrazeneca Uk Ltd | Verfahren zur herstellung von pyrimidinverbindungen |
CN101775000B (zh) * | 2003-05-02 | 2014-09-24 | 中化帝斯曼制药有限公司荷兰公司 | 制备(4-羟基-6-氧-四氢吡喃-2-基)乙腈及其衍生物的方法 |
GB0312896D0 (en) * | 2003-06-05 | 2003-07-09 | Astrazeneca Ab | Chemical process |
US8346482B2 (en) | 2003-08-22 | 2013-01-01 | Fernandez Dennis S | Integrated biosensor and simulation system for diagnosis and therapy |
UY28501A1 (es) | 2003-09-10 | 2005-04-29 | Astrazeneca Uk Ltd | Compuestos químicos |
GB0321827D0 (en) * | 2003-09-18 | 2003-10-15 | Astrazeneca Uk Ltd | Chemical compounds |
GB0324791D0 (en) * | 2003-10-24 | 2003-11-26 | Astrazeneca Ab | Chemical process |
DE10352659B4 (de) * | 2003-11-11 | 2007-09-13 | Ratiopharm Gmbh | Verfahren zur Herstellung von Statinen und Tetrahydropyranonderivate zur Verwendung in dem Verfahren |
GB0428328D0 (en) * | 2004-12-24 | 2005-02-02 | Astrazeneca Uk Ltd | Chemical process |
GB0514078D0 (en) * | 2005-07-08 | 2005-08-17 | Astrazeneca Uk Ltd | Chemical process |
US7264743B2 (en) * | 2006-01-23 | 2007-09-04 | Lam Research Corporation | Fin structure formation |
TW200831469A (en) * | 2006-12-01 | 2008-08-01 | Astrazeneca Uk Ltd | Chemical process |
PT2419407E (pt) * | 2009-04-15 | 2013-01-28 | Pharmathen Sa | Processo melhorado para a preparação de fluvastatina e dos seus sais |
GB2482525A (en) * | 2010-08-05 | 2012-02-08 | Phoenix Chemicals Ltd | A process for the production of acyloxymethyldioxanylacetic derivatives |
WO2012032035A1 (en) | 2010-09-09 | 2012-03-15 | Dsm Sinochem Pharmaceuticals Netherlands B.V. | Salts of 7-amino-3,5-dihydroxyheptanoic acid esters |
MX2013002809A (es) | 2010-09-16 | 2013-04-29 | Dsm Sinochem Pharm Nl Bv | Esteres de acidos hexanoicos. |
MX357470B (es) | 2011-01-18 | 2018-07-11 | Dsm Sinochem Pharm Nl Bv | Procedimiento para la preparación de estatinas en presencia de base. |
MX353510B (es) | 2011-01-18 | 2018-01-17 | Dsm Sinochem Pharm Nl Bv | Sulfuros y sulfonas de metiltetrazol. |
PL2665722T3 (pl) | 2011-01-18 | 2017-03-31 | Dsm Sinochem Pharmaceuticals Netherlands B.V. | Sposób otrzymywania diolosulfonów |
JP6065862B2 (ja) * | 2013-04-10 | 2017-01-25 | 信越化学工業株式会社 | パターン形成方法、レジスト組成物、高分子化合物及び単量体 |
WO2014203045A1 (en) | 2013-06-20 | 2014-12-24 | Lupin Limited | A novel, green and cost effective process for synthesis of tert-butyl (3r,5s)-6-oxo-3,5-dihydroxy-3,5-o-isopropylidene-hexanoate |
CN105624127B (zh) * | 2014-10-28 | 2019-07-26 | 上海弈柯莱生物医药科技有限公司 | 一种葡萄糖脱氢酶及其在合成他汀类药物中间体中的应用 |
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NL1015744C2 (nl) | 2000-07-19 | 2002-01-22 | Dsm Nv | Werkwijze voor de bereiding van 2-(6-gesubstitueerde-1,3-dioxan-4-yl) azijnzuurderivaten. |
CN100349877C (zh) | 2001-07-13 | 2007-11-21 | 阿斯特拉曾尼卡英国有限公司 | 氨基嘧啶化合物的制备方法 |
EP1323717A1 (en) | 2001-12-27 | 2003-07-02 | Dsm N.V. | Process for the preparation of 2-(6-Substituted-1,3-Dioxane-4-yL) acetic acid derivatives |
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EP1375493A1 (en) | 2002-06-17 | 2004-01-02 | Dsm N.V. | Process for the preparation of an dioxane acetic acid ester |
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GB0324791D0 (en) * | 2003-10-24 | 2003-11-26 | Astrazeneca Ab | Chemical process |
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-
2000
- 2000-07-19 NL NL1015744A patent/NL1015744C2/nl not_active IP Right Cessation
-
2001
- 2001-07-12 KR KR1020027017684A patent/KR100865016B1/ko not_active IP Right Cessation
- 2001-07-12 CA CA002415963A patent/CA2415963C/en not_active Expired - Fee Related
- 2001-07-12 ES ES01953373T patent/ES2272506T3/es not_active Expired - Lifetime
- 2001-07-12 EE EEP200300024A patent/EE200300024A/xx unknown
- 2001-07-12 WO PCT/NL2001/000535 patent/WO2002006266A1/en active Application Filing
- 2001-07-12 PT PT01953373T patent/PT1317440E/pt unknown
- 2001-07-12 CN CN2007101118797A patent/CN101081842B/zh not_active Expired - Lifetime
- 2001-07-12 BR BR0112535-4A patent/BR0112535A/pt not_active IP Right Cessation
- 2001-07-12 CZ CZ20030163A patent/CZ302718B6/cs not_active IP Right Cessation
- 2001-07-12 DE DE60123444T patent/DE60123444T2/de not_active Expired - Lifetime
- 2001-07-12 AU AU2001275830A patent/AU2001275830B2/en not_active Ceased
- 2001-07-12 AU AU7583001A patent/AU7583001A/xx active Pending
- 2001-07-12 IL IL15398001A patent/IL153980A0/xx active IP Right Grant
- 2001-07-12 HU HU0303166A patent/HUP0303166A3/hu unknown
- 2001-07-12 EP EP06010837A patent/EP1700854B1/en not_active Expired - Lifetime
- 2001-07-12 KR KR1020087019878A patent/KR20080078925A/ko active Search and Examination
- 2001-07-12 JP JP2002512170A patent/JP5006499B2/ja not_active Expired - Lifetime
- 2001-07-12 US US10/333,351 patent/US6870059B2/en not_active Expired - Lifetime
- 2001-07-12 CN CNB2005100657442A patent/CN100378091C/zh not_active Expired - Lifetime
- 2001-07-12 EP EP01953373A patent/EP1317440B1/en not_active Expired - Lifetime
- 2001-07-12 MX MXPA03000498A patent/MXPA03000498A/es active IP Right Grant
- 2001-07-12 PL PL359332A patent/PL207115B1/pl not_active IP Right Cessation
- 2001-07-12 SK SK35-2003A patent/SK287755B6/sk not_active IP Right Cessation
- 2001-07-12 ES ES06010837T patent/ES2387313T3/es not_active Expired - Lifetime
- 2001-07-12 RU RU2003104825/04A patent/RU2266903C2/ru not_active IP Right Cessation
- 2001-07-12 SK SK123-2010A patent/SK287756B6/sk not_active IP Right Cessation
- 2001-07-12 CN CN01812999A patent/CN1443183A/zh not_active Withdrawn
- 2001-07-12 NZ NZ523703A patent/NZ523703A/en not_active IP Right Cessation
- 2001-07-12 DK DK01953373T patent/DK1317440T3/da active
- 2001-07-12 AT AT01953373T patent/ATE340790T1/de active
- 2001-07-12 KR KR1020077027471A patent/KR20070121063A/ko active Search and Examination
- 2001-12-07 UA UA2003010456A patent/UA77944C2/uk unknown
-
2003
- 2003-01-03 NO NO20030025A patent/NO328935B1/no not_active IP Right Cessation
- 2003-01-15 IS IS6680A patent/IS2386B/is unknown
- 2003-01-16 IL IL153980A patent/IL153980A/en not_active IP Right Cessation
- 2003-01-17 ZA ZA200300478A patent/ZA200300478B/en unknown
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2005
- 2005-02-07 US US11/053,090 patent/US7642363B2/en not_active Expired - Lifetime
-
2006
- 2006-08-31 IL IL177824A patent/IL177824A0/en not_active IP Right Cessation
- 2006-12-21 CY CY20061101848T patent/CY1105881T1/el unknown
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2007
- 2007-03-01 HK HK07102328.2A patent/HK1097260A1/xx not_active IP Right Cessation
- 2007-11-15 IS IS8690A patent/IS8690A/is unknown
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2009
- 2009-11-24 US US12/625,156 patent/US7989643B2/en not_active Expired - Fee Related
-
2011
- 2011-06-22 US US13/166,607 patent/US20110251406A1/en not_active Abandoned
- 2011-12-06 JP JP2011267056A patent/JP2012111757A/ja active Pending
Cited By (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN103974946A (zh) * | 2011-12-09 | 2014-08-06 | 中化帝斯曼制药有限公司荷兰公司 | 制备他汀前体的方法 |
CN103987705A (zh) * | 2011-12-09 | 2014-08-13 | 中化帝斯曼制药有限公司荷兰公司 | 制备他汀含硫前体的方法 |
CN103987705B (zh) * | 2011-12-09 | 2015-09-30 | 中化帝斯曼制药有限公司荷兰公司 | 制备他汀含硫前体的方法 |
CN103974946B (zh) * | 2011-12-09 | 2017-09-29 | 中化帝斯曼制药有限公司荷兰公司 | 制备他汀前体的方法 |
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