PT2419407E - Processo melhorado para a preparação de fluvastatina e dos seus sais - Google Patents

Processo melhorado para a preparação de fluvastatina e dos seus sais

Info

Publication number
PT2419407E
PT2419407E PT97765341T PT09776534T PT2419407E PT 2419407 E PT2419407 E PT 2419407E PT 97765341 T PT97765341 T PT 97765341T PT 09776534 T PT09776534 T PT 09776534T PT 2419407 E PT2419407 E PT 2419407E
Authority
PT
Portugal
Prior art keywords
fluvastatin
salts
preparation
improved process
improved
Prior art date
Application number
PT97765341T
Other languages
English (en)
Inventor
Theoharis V Koftis
Theodoros Panagiotidis
Rohit Ravikant Soni
Alexandra Lithadioti
Original Assignee
Pharmathen Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pharmathen Sa filed Critical Pharmathen Sa
Publication of PT2419407E publication Critical patent/PT2419407E/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/18—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D209/24—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with an alkyl or cycloalkyl radical attached to the ring nitrogen atom
PT97765341T 2009-04-15 2009-04-15 Processo melhorado para a preparação de fluvastatina e dos seus sais PT2419407E (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/EP2009/002745 WO2010118757A1 (en) 2009-04-15 2009-04-15 Improved process for the preparation of fluvastatin and salts thereof

Publications (1)

Publication Number Publication Date
PT2419407E true PT2419407E (pt) 2013-01-28

Family

ID=40790820

Family Applications (1)

Application Number Title Priority Date Filing Date
PT97765341T PT2419407E (pt) 2009-04-15 2009-04-15 Processo melhorado para a preparação de fluvastatina e dos seus sais

Country Status (5)

Country Link
US (1) US20120035374A1 (pt)
EP (1) EP2419407B1 (pt)
ES (1) ES2398802T3 (pt)
PT (1) PT2419407E (pt)
WO (1) WO2010118757A1 (pt)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104250222A (zh) * 2013-06-27 2014-12-31 上海朴颐化学科技有限公司 一种氟伐醇酮制备工艺改进方法
CN115389655B (zh) * 2022-08-11 2024-04-09 唯智医药科技（北京）有限公司 6-甲醛基-2,2二甲基-1,3-二氧六环-4-乙酸叔丁酯异构体杂质检测

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2194202T3 (es) * 1996-06-24 2003-11-16 Novartis Ag Compuestos polimorfos.
NL1015744C2 (nl) * 2000-07-19 2002-01-22 Dsm Nv Werkwijze voor de bereiding van 2-(6-gesubstitueerde-1,3-dioxan-4-yl) azijnzuurderivaten.
JP2007524619A (ja) * 2003-06-18 2007-08-30 テバ ファーマシューティカル インダストリーズ リミティド フルバスタチンナトリウム結晶型、その調製方法、これを含有する組成物、およびその使用法
ES2327668T3 (es) * 2006-04-20 2009-11-02 F.I.S. Fabbrica Italiana Sintetici S.P.A. Procedimiento para la preparacion de sal sodica de fluvastatina.

Also Published As

Publication number Publication date
US20120035374A1 (en) 2012-02-09
ES2398802T3 (es) 2013-03-21
EP2419407B1 (en) 2012-11-14
WO2010118757A1 (en) 2010-10-21
EP2419407A1 (en) 2012-02-22

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