MX363563B - Proceso para la preparación de un tioprecursor de estatinas. - Google Patents

Proceso para la preparación de un tioprecursor de estatinas.

Info

Publication number
MX363563B
MX363563B MX2014006893A MX2014006893A MX363563B MX 363563 B MX363563 B MX 363563B MX 2014006893 A MX2014006893 A MX 2014006893A MX 2014006893 A MX2014006893 A MX 2014006893A MX 363563 B MX363563 B MX 363563B
Authority
MX
Mexico
Prior art keywords
preparation
statins
thioprecursor
precursor
medicament
Prior art date
Application number
MX2014006893A
Other languages
English (en)
Other versions
MX2014006893A (es
Inventor
De Lange Ben
Heemskerk Dennis
Henderika Maria Bessembinder Karin
Original Assignee
Dsm Sinochem Pharm Nl Bv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dsm Sinochem Pharm Nl Bv filed Critical Dsm Sinochem Pharm Nl Bv
Publication of MX2014006893A publication Critical patent/MX2014006893A/es
Publication of MX363563B publication Critical patent/MX363563B/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D319/00—Heterocyclic compounds containing six-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D319/04—1,3-Dioxanes; Hydrogenated 1,3-dioxanes
    • C07D319/06—1,3-Dioxanes; Hydrogenated 1,3-dioxanes not condensed with other rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

La presente invención se refiere a un proceso para la preparación de un precursor para la síntesis de estatinas derivadas del ácido hexanoico y al uso de dicho precursor en la fabricación de un medicamento.
MX2014006893A 2011-12-09 2012-12-06 Proceso para la preparación de un tioprecursor de estatinas. MX363563B (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP11192749 2011-12-09
PCT/EP2012/074689 WO2013083719A1 (en) 2011-12-09 2012-12-06 Process for the preparation of a thioprecursor for statins

Publications (2)

Publication Number Publication Date
MX2014006893A MX2014006893A (es) 2014-09-04
MX363563B true MX363563B (es) 2019-03-27

Family

ID=47291022

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2014006893A MX363563B (es) 2011-12-09 2012-12-06 Proceso para la preparación de un tioprecursor de estatinas.

Country Status (10)

Country Link
US (1) US9260423B2 (es)
EP (1) EP2788341B1 (es)
CN (1) CN103987705B (es)
ES (1) ES2623495T3 (es)
HK (1) HK1201063A1 (es)
HU (1) HUE032936T2 (es)
IL (1) IL232804A (es)
MX (1) MX363563B (es)
SI (1) SI2788341T1 (es)
WO (1) WO2013083719A1 (es)

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP3803551B2 (ja) 1998-08-05 2006-08-02 株式会社カネカ 光学活性２−［６−（ヒドロキシメチル）−１，３−ジオキサン−４−イル］酢酸誘導体の製造法
GB9903472D0 (en) 1999-02-17 1999-04-07 Zeneca Ltd Chemical process
US20020028826A1 (en) 2000-06-15 2002-03-07 Robl Jeffrey A. HMG-CoA reductase inhibitors and method
NL1015744C2 (nl) 2000-07-19 2002-01-22 Dsm Nv Werkwijze voor de bereiding van 2-(6-gesubstitueerde-1,3-dioxan-4-yl) azijnzuurderivaten.
IL158525A0 (en) * 2001-06-06 2004-05-12 Bristol Myers Squibb Co A process for preparing chiral diol sulfone derivatives
ES2282433T3 (es) 2001-07-12 2007-10-16 Dsm Ip Assets B.V. Procedimiento para la preparacion de 2,4-didesoxihexosas y 2,4,6-tridesoxihexosas.
CZ299215B6 (cs) 2005-06-29 2008-05-21 Zentiva, A. S. Zpusob výroby hemivápenaté soli (E)-7-[4-(4-fluorofenyl)-6-isopropyl-2-[methyl(methylsulfonyl)amino]pyrimidin-5-yl] (3R,5S)-3,5-dihydroxy-6-heptenovékyseliny

Also Published As

Publication number Publication date
CN103987705A (zh) 2014-08-13
WO2013083719A1 (en) 2013-06-13
SI2788341T1 (sl) 2017-06-30
EP2788341B1 (en) 2017-04-05
CN103987705B (zh) 2015-09-30
ES2623495T3 (es) 2017-07-11
EP2788341A1 (en) 2014-10-15
IL232804A0 (en) 2014-08-03
HK1201063A1 (en) 2015-08-21
US9260423B2 (en) 2016-02-16
US20140343292A1 (en) 2014-11-20
HUE032936T2 (en) 2017-11-28
IL232804A (en) 2017-01-31
MX2014006893A (es) 2014-09-04

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