MX359424B - Proceso para la preparación de un precursor de estatina. - Google Patents

Proceso para la preparación de un precursor de estatina.

Info

Publication number
MX359424B
MX359424B MX2014006891A MX2014006891A MX359424B MX 359424 B MX359424 B MX 359424B MX 2014006891 A MX2014006891 A MX 2014006891A MX 2014006891 A MX2014006891 A MX 2014006891A MX 359424 B MX359424 B MX 359424B
Authority
MX
Mexico
Prior art keywords
preparation
precursor
statin
statin precursor
medicament
Prior art date
Application number
MX2014006891A
Other languages
English (en)
Other versions
MX2014006891A (es
Inventor
De Lange Ben
Heemskerk Dennis
Henderika Bessembinder Karin
Original Assignee
Dsm Sinochem Pharm Nl Bv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dsm Sinochem Pharm Nl Bv filed Critical Dsm Sinochem Pharm Nl Bv
Publication of MX2014006891A publication Critical patent/MX2014006891A/es
Publication of MX359424B publication Critical patent/MX359424B/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D319/00—Heterocyclic compounds containing six-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D319/04—1,3-Dioxanes; Hydrogenated 1,3-dioxanes
    • C07D319/06—1,3-Dioxanes; Hydrogenated 1,3-dioxanes not condensed with other rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/96—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

La presente invención se refiere a un proceso para la preparación de un precursor para la síntesis de estatinas derivadas de ácido hexanoico y al uso de dicho precursor en la fabricación de un medicamento.
MX2014006891A 2011-12-09 2012-12-06 Proceso para la preparación de un precursor de estatina. MX359424B (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP11192748 2011-12-09
PCT/EP2012/074688 WO2013083718A1 (en) 2011-12-09 2012-12-06 Process for the preparation of a statin precursor

Publications (2)

Publication Number Publication Date
MX2014006891A MX2014006891A (es) 2014-09-04
MX359424B true MX359424B (es) 2018-09-12

Family

ID=47424897

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2014006891A MX359424B (es) 2011-12-09 2012-12-06 Proceso para la preparación de un precursor de estatina.

Country Status (7)

Country Link
US (1) US8987478B2 (es)
EP (1) EP2788342B1 (es)
CN (1) CN103974946B (es)
HK (1) HK1201062A1 (es)
IL (1) IL232803A (es)
MX (1) MX359424B (es)
WO (1) WO2013083718A1 (es)

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9903472D0 (en) 1999-02-17 1999-04-07 Zeneca Ltd Chemical process
US20020028826A1 (en) 2000-06-15 2002-03-07 Robl Jeffrey A. HMG-CoA reductase inhibitors and method
NL1015744C2 (nl) * 2000-07-19 2002-01-22 Dsm Nv Werkwijze voor de bereiding van 2-(6-gesubstitueerde-1,3-dioxan-4-yl) azijnzuurderivaten.
US6875867B2 (en) * 2001-06-06 2005-04-05 Bristol-Myers Squibb Company Process for preparing chiral diol sulfones and dihydroxy acid HMG CoA reductase inhibitors
JP4248392B2 (ja) 2001-07-12 2009-04-02 ディーエスエム アイピー アセッツ ビー．ブイ． ２，４−ジデオキシヘキソース及び２，４，６−トリデオキシヘキソースの製造方法
CZ299215B6 (cs) 2005-06-29 2008-05-21 Zentiva, A. S. Zpusob výroby hemivápenaté soli (E)-7-[4-(4-fluorofenyl)-6-isopropyl-2-[methyl(methylsulfonyl)amino]pyrimidin-5-yl] (3R,5S)-3,5-dihydroxy-6-heptenovékyseliny

Also Published As

Publication number Publication date
HK1201062A1 (en) 2015-08-21
MX2014006891A (es) 2014-09-04
WO2013083718A1 (en) 2013-06-13
IL232803A0 (en) 2014-08-03
EP2788342A1 (en) 2014-10-15
US20140357864A1 (en) 2014-12-04
EP2788342B1 (en) 2018-01-24
IL232803A (en) 2017-01-31
CN103974946B (zh) 2017-09-29
CN103974946A (zh) 2014-08-06
US8987478B2 (en) 2015-03-24

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