MX347541B - Analogos de acido sialico. - Google Patents
Analogos de acido sialico.Info
- Publication number
- MX347541B MX347541B MX2014004928A MX2014004928A MX347541B MX 347541 B MX347541 B MX 347541B MX 2014004928 A MX2014004928 A MX 2014004928A MX 2014004928 A MX2014004928 A MX 2014004928A MX 347541 B MX347541 B MX 347541B
- Authority
- MX
- Mexico
- Prior art keywords
- sialic acid
- acid analogs
- analogs
- treatment
- present
- Prior art date
Links
- SQVRNKJHWKZAKO-OQPLDHBCSA-N sialic acid Chemical class CC(=O)N[C@@H]1[C@@H](O)C[C@@](O)(C(O)=O)OC1[C@H](O)[C@H](O)CO SQVRNKJHWKZAKO-OQPLDHBCSA-N 0.000 title abstract 3
- SQVRNKJHWKZAKO-UHFFFAOYSA-N beta-N-Acetyl-D-neuraminic acid Natural products CC(=O)NC1C(O)CC(O)(C(O)=O)OC1C(O)C(O)CO SQVRNKJHWKZAKO-UHFFFAOYSA-N 0.000 abstract 1
- 230000007812 deficiency Effects 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H7/00—Compounds containing non-saccharide radicals linked to saccharide radicals by a carbon-to-carbon bond
- C07H7/02—Acyclic radicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
- C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
- C07D493/08—Bridged systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H13/00—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids
- C07H13/02—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids
- C07H13/04—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids having the esterifying carboxyl radicals attached to acyclic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H13/00—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids
- C07H13/02—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids
- C07H13/10—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids having the esterifying carboxyl radicals directly attached to heterocyclic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H7/00—Compounds containing non-saccharide radicals linked to saccharide radicals by a carbon-to-carbon bond
- C07H7/02—Acyclic radicals
- C07H7/027—Keto-aldonic acids
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Physical Education & Sports Medicine (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Animal Behavior & Ethology (AREA)
- Neurology (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Medicinal Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
- Medicinal Preparation (AREA)
Abstract
La presente invención proporciona análogos de ácido siálico y sus composiciones útiles para el tratamiento de deficiencias de ácido siálico.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201161550610P | 2011-10-24 | 2011-10-24 | |
| PCT/US2012/061737 WO2013063149A1 (en) | 2011-10-24 | 2012-10-24 | Sialic acid analogs |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| MX2014004928A MX2014004928A (es) | 2014-11-10 |
| MX347541B true MX347541B (es) | 2017-04-28 |
Family
ID=48168447
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2014004928A MX347541B (es) | 2011-10-24 | 2012-10-24 | Analogos de acido sialico. |
Country Status (13)
| Country | Link |
|---|---|
| US (5) | US8840926B2 (es) |
| EP (1) | EP2771348B1 (es) |
| JP (1) | JP6196224B2 (es) |
| KR (1) | KR102049214B1 (es) |
| CN (1) | CN103974965B (es) |
| AU (1) | AU2012328874B2 (es) |
| BR (1) | BR112014009760B1 (es) |
| CA (1) | CA2849114C (es) |
| ES (1) | ES2807890T3 (es) |
| HK (1) | HK1201067A1 (es) |
| IL (1) | IL231714B (es) |
| MX (1) | MX347541B (es) |
| WO (1) | WO2013063149A1 (es) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9241896B2 (en) | 2008-12-19 | 2016-01-26 | Ultragenyx Pharmaceutical Inc. | Methods and formulations for treating sialic acid deficiencies |
| AU2011279158B2 (en) | 2010-07-13 | 2015-07-09 | Ultragenyx Pharmaceutical Inc. | Method and formulations for treating sialic acid deficiencies |
| US8840926B2 (en) | 2011-10-24 | 2014-09-23 | Ultragenyx Pharmaceutical Inc. | Sialic acid analogs |
| EP2804600A4 (en) * | 2012-01-18 | 2015-09-02 | Ultragenyx Pharmaceutical Inc | METHODS AND FORMULATIONS FOR TREATING SIALIC ACID DEFICIENCIES |
| WO2017048817A1 (en) | 2015-09-14 | 2017-03-23 | Ultragenyx Pharmaceutical Inc. | Crystal forms of sialic acid or salt or solvate thereof |
| EP4665860A1 (en) * | 2023-02-17 | 2025-12-24 | Ultragenyx Pharmaceutical Inc. | Crystalline forms of sialic acid derivatives and methods for their use |
Family Cites Families (26)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS6168418A (ja) | 1984-09-11 | 1986-04-08 | Kanto Ishi Pharma Co Ltd | 去痰薬 |
| JPS63139193A (ja) * | 1986-11-28 | 1988-06-10 | Mect Corp | シアル酸誘導体１，７−ラクトン |
| US6156544A (en) | 1993-06-09 | 2000-12-05 | Glaxo Group Limited | Process for the preparation of N-acetylneuraminic acid |
| AU721276B2 (en) | 1995-04-04 | 2000-06-29 | Wound Healing Of Oklahoma | Cancer treatment by photodynamic therapy, in combination with an immunoadjuvant |
| US5624677A (en) | 1995-06-13 | 1997-04-29 | Pentech Pharmaceuticals, Inc. | Controlled release of drugs delivered by sublingual or buccal administration |
| WO1999052931A1 (fr) | 1998-04-10 | 1999-10-21 | Mitsubishi Chemical Corporation | Dispersion solide contenant un derive d'acide sialique |
| KR20030006721A (ko) | 2001-07-14 | 2003-01-23 | 삼성전자 주식회사 | 리소그라피 시스템 및 이를 이용한 레티클 표면의 파티클제거방법 |
| ATE503498T1 (de) | 2002-06-21 | 2011-04-15 | Novo Nordisk Healthcare Ag | Pegylierte glykoformen von faktor vii |
| US7238677B2 (en) | 2003-03-28 | 2007-07-03 | Kimberly-Clark Worldwide, Inc. | Prevention of urogenital infections |
| EP1697481A2 (en) * | 2003-12-09 | 2006-09-06 | Spherics, Inc. | Bioadhesive polymers with catechol functionality |
| NZ561116A (en) | 2005-03-03 | 2010-02-26 | Mannatech Inc | Methods and compositions for modified release of nutritional supplements |
| WO2007103286A2 (en) * | 2006-03-02 | 2007-09-13 | Spherics, Inc. | Rate-controlled bioadhesive oral dosage formulations |
| WO2008027557A2 (en) * | 2006-08-31 | 2008-03-06 | Spherics, Inc. | Topiramate compositions and methods of enhancing its bioavailability |
| CA2680842C (en) | 2007-05-31 | 2015-11-24 | Government Of The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services National Institutes Of Health | N-acetyl mannosamine or derivatives thereof for use in treating a kidney disorder in a mammal |
| US20090081249A1 (en) | 2007-08-27 | 2009-03-26 | Massachusetts Institute Of Technology | Bi-Functional Polymer-Attached Inhibitors of Influenza Virus |
| WO2009137827A2 (en) | 2008-05-09 | 2009-11-12 | Tiara Pharmaceuticals, Inc. | Controlled release of n-acetylcysteine (nac) for reduction of systemic and/or vascular inflammation |
| KR101116864B1 (ko) | 2008-08-01 | 2012-02-29 | 주식회사 베네비오 | 고지혈증, 지방간 또는 비만의 예방 또는 치료용 조성물 |
| US20100159001A1 (en) | 2008-12-19 | 2010-06-24 | Cardinal John R | Extended-Release Pharmaceutical Formulations |
| US20100160363A1 (en) | 2008-12-19 | 2010-06-24 | Aaipharma Services Corp. | Extended-release pharmaceutical formulations |
| US9241896B2 (en) | 2008-12-19 | 2016-01-26 | Ultragenyx Pharmaceutical Inc. | Methods and formulations for treating sialic acid deficiencies |
| JP5626734B2 (ja) * | 2009-05-15 | 2014-11-19 | 公益財団法人ヒューマンサイエンス振興財団 | Ｇｎｅタンパク質の機能低下に起因する疾患の治療用医薬剤、食品組成物 |
| AU2011279158B2 (en) | 2010-07-13 | 2015-07-09 | Ultragenyx Pharmaceutical Inc. | Method and formulations for treating sialic acid deficiencies |
| US8840926B2 (en) | 2011-10-24 | 2014-09-23 | Ultragenyx Pharmaceutical Inc. | Sialic acid analogs |
| EP2804600A4 (en) | 2012-01-18 | 2015-09-02 | Ultragenyx Pharmaceutical Inc | METHODS AND FORMULATIONS FOR TREATING SIALIC ACID DEFICIENCIES |
| EP3252065B1 (en) | 2015-01-28 | 2020-01-08 | Kyowa Hakko Bio Co., Ltd. | Crystal of ammonium n-acetylneuraminate anhydrate, and process for producing same |
| WO2017048817A1 (en) | 2015-09-14 | 2017-03-23 | Ultragenyx Pharmaceutical Inc. | Crystal forms of sialic acid or salt or solvate thereof |
-
2012
- 2012-10-24 US US13/659,550 patent/US8840926B2/en active Active
- 2012-10-24 MX MX2014004928A patent/MX347541B/es active IP Right Grant
- 2012-10-24 ES ES12843460T patent/ES2807890T3/es active Active
- 2012-10-24 WO PCT/US2012/061737 patent/WO2013063149A1/en not_active Ceased
- 2012-10-24 AU AU2012328874A patent/AU2012328874B2/en active Active
- 2012-10-24 HK HK15101526.4A patent/HK1201067A1/xx unknown
- 2012-10-24 JP JP2014537380A patent/JP6196224B2/ja active Active
- 2012-10-24 EP EP12843460.2A patent/EP2771348B1/en active Active
- 2012-10-24 CN CN201280052218.0A patent/CN103974965B/zh active Active
- 2012-10-24 CA CA2849114A patent/CA2849114C/en active Active
- 2012-10-24 BR BR112014009760-7A patent/BR112014009760B1/pt active IP Right Grant
- 2012-10-24 KR KR1020147013997A patent/KR102049214B1/ko active Active
-
2014
- 2014-03-26 IL IL231714A patent/IL231714B/en active IP Right Grant
- 2014-08-15 US US14/461,295 patent/US9221858B2/en active Active
-
2015
- 2015-11-18 US US14/944,779 patent/US10065981B2/en active Active
-
2018
- 2018-07-31 US US16/050,343 patent/US10457701B2/en active Active
-
2019
- 2019-09-16 US US16/571,589 patent/US10889607B2/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| CA2849114A1 (en) | 2013-05-02 |
| JP2014530882A (ja) | 2014-11-20 |
| EP2771348A1 (en) | 2014-09-03 |
| EP2771348B1 (en) | 2020-05-20 |
| AU2012328874B2 (en) | 2017-08-31 |
| EP2771348A4 (en) | 2015-09-09 |
| US9221858B2 (en) | 2015-12-29 |
| MX2014004928A (es) | 2014-11-10 |
| CN103974965A (zh) | 2014-08-06 |
| CA2849114C (en) | 2020-12-15 |
| IL231714A0 (en) | 2014-05-28 |
| US20190127409A1 (en) | 2019-05-02 |
| BR112014009760B1 (pt) | 2022-11-29 |
| CN103974965B (zh) | 2019-09-24 |
| KR20140084277A (ko) | 2014-07-04 |
| KR102049214B1 (ko) | 2019-11-28 |
| WO2013063149A1 (en) | 2013-05-02 |
| US20200131215A1 (en) | 2020-04-30 |
| AU2012328874A1 (en) | 2014-04-10 |
| US10457701B2 (en) | 2019-10-29 |
| BR112014009760A2 (pt) | 2017-04-18 |
| US8840926B2 (en) | 2014-09-23 |
| US10065981B2 (en) | 2018-09-04 |
| JP6196224B2 (ja) | 2017-09-13 |
| ES2807890T3 (es) | 2021-02-24 |
| IL231714B (en) | 2018-10-31 |
| US20130122094A1 (en) | 2013-05-16 |
| US10889607B2 (en) | 2021-01-12 |
| HK1201067A1 (en) | 2015-08-21 |
| BR112014009760A8 (pt) | 2018-01-16 |
| US20160297846A1 (en) | 2016-10-13 |
| US20150038693A1 (en) | 2015-02-05 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG | Grant or registration |