EP2804600A4 - Methods and formulations for treating sialic acid deficiencies - Google Patents

Methods and formulations for treating sialic acid deficiencies

Info

Publication number
EP2804600A4
EP2804600A4 EP13739040.7A EP13739040A EP2804600A4 EP 2804600 A4 EP2804600 A4 EP 2804600A4 EP 13739040 A EP13739040 A EP 13739040A EP 2804600 A4 EP2804600 A4 EP 2804600A4
Authority
EP
European Patent Office
Prior art keywords
formulations
methods
sialic acid
acid deficiencies
treating sialic
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP13739040.7A
Other languages
German (de)
French (fr)
Other versions
EP2804600A2 (en
Inventor
Emil D Kakkis
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Ultragenyx Pharmaceutical Inc
Original Assignee
Ultragenyx Pharmaceutical Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ultragenyx Pharmaceutical Inc filed Critical Ultragenyx Pharmaceutical Inc
Publication of EP2804600A2 publication Critical patent/EP2804600A2/en
Publication of EP2804600A4 publication Critical patent/EP2804600A4/en
Withdrawn legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7012—Compounds having a free or esterified carboxyl group attached, directly or through a carbon chain, to a carbon atom of the saccharide radical, e.g. glucuronic acid, neuraminic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0002—Galenical forms characterised by the drug release technique; Application systems commanded by energy
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
EP13739040.7A 2012-01-18 2013-01-18 Methods and formulations for treating sialic acid deficiencies Withdrawn EP2804600A4 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201261588069P 2012-01-18 2012-01-18
US201261709549P 2012-10-04 2012-10-04
PCT/US2013/022167 WO2013109906A2 (en) 2012-01-18 2013-01-18 Methods and formulations for treating sialic acid deficiencies

Publications (2)

Publication Number Publication Date
EP2804600A2 EP2804600A2 (en) 2014-11-26
EP2804600A4 true EP2804600A4 (en) 2015-09-02

Family

ID=48799814

Family Applications (1)

Application Number Title Priority Date Filing Date
EP13739040.7A Withdrawn EP2804600A4 (en) 2012-01-18 2013-01-18 Methods and formulations for treating sialic acid deficiencies

Country Status (9)

Country Link
EP (1) EP2804600A4 (en)
JP (2) JP2015504094A (en)
KR (1) KR20150000872A (en)
CN (1) CN104271125A (en)
AU (1) AU2013209610B2 (en)
BR (1) BR112014017587A8 (en)
CA (1) CA2862836A1 (en)
IL (1) IL233225A0 (en)
WO (1) WO2013109906A2 (en)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9241896B2 (en) 2008-12-19 2016-01-26 Ultragenyx Pharmaceutical Inc. Methods and formulations for treating sialic acid deficiencies
CA2805222A1 (en) 2010-07-13 2012-01-19 Ultragenyx Pharmaceutical Inc. Methods and formulations for treating sialic acid deficiencies
BR112014009760B1 (en) 2011-10-24 2022-11-29 Ultragenyx Pharmaceutical Inc SIALIC ACID ANALOGS, THEIR USE AND PHARMACEUTICAL COMPOSITION
WO2017048817A1 (en) 2015-09-14 2017-03-23 Ultragenyx Pharmaceutical Inc. Crystal forms of sialic acid or salt or solvate thereof
EP3486326A1 (en) 2017-11-21 2019-05-22 Jennewein Biotechnologie GmbH Method for the purification of n-acetylneuraminic acid from a fermentation broth
CN117969774B (en) * 2024-04-02 2024-06-11 小仙炖霸州食品有限公司 Automatic change bird's nest and detect and grading system

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2008150477A2 (en) * 2007-05-31 2008-12-11 Government Of The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services National Institutes Of Health N-acetyl mannosamine as a therapeutic agent
US20100159001A1 (en) * 2008-12-19 2010-06-24 Cardinal John R Extended-Release Pharmaceutical Formulations
WO2010131712A1 (en) * 2009-05-15 2010-11-18 財団法人ヒューマンサイエンス振興財団 Therapeutic pharmaceutical agent for diseases associated with decrease in function of gne protein, food composition, and food additive
WO2012009474A1 (en) * 2010-07-13 2012-01-19 Ultragenyx Pharmaceutical Inc. Method and formulations for treating sialic acid deficiencies
WO2013063149A1 (en) * 2011-10-24 2013-05-02 Ultragenyx Pharmaceutical, Inc. Sialic acid analogs

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2008150477A2 (en) * 2007-05-31 2008-12-11 Government Of The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services National Institutes Of Health N-acetyl mannosamine as a therapeutic agent
US20100159001A1 (en) * 2008-12-19 2010-06-24 Cardinal John R Extended-Release Pharmaceutical Formulations
WO2010131712A1 (en) * 2009-05-15 2010-11-18 財団法人ヒューマンサイエンス振興財団 Therapeutic pharmaceutical agent for diseases associated with decrease in function of gne protein, food composition, and food additive
US20120264928A1 (en) * 2009-05-15 2012-10-18 Japan Health Sciences Foundation Therapeutic pharmaceutical agent for diseases associated with decrease in function of gne protein, food composition, and food additive
WO2012009474A1 (en) * 2010-07-13 2012-01-19 Ultragenyx Pharmaceutical Inc. Method and formulations for treating sialic acid deficiencies
WO2013063149A1 (en) * 2011-10-24 2013-05-02 Ultragenyx Pharmaceutical, Inc. Sialic acid analogs

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
MAY CHRISTINE V MALICDAN ET AL: "Prophylactic treatment with sialic acid metabolites precludes the development of the myopathic phenotype in the DMRV-hIBM mouse model", NATURE MEDICINE, vol. 15, no. 6, 1 June 2009 (2009-06-01), pages 690 - 695, XP055175431, ISSN: 1078-8956, DOI: 10.1038/nm.1956 *

Also Published As

Publication number Publication date
BR112014017587A8 (en) 2017-07-04
IL233225A0 (en) 2014-08-31
EP2804600A2 (en) 2014-11-26
AU2013209610A1 (en) 2014-07-10
JP2015504094A (en) 2015-02-05
CN104271125A (en) 2015-01-07
JP2017186381A (en) 2017-10-12
KR20150000872A (en) 2015-01-05
AU2013209610B2 (en) 2017-11-30
BR112014017587A2 (en) 2017-06-13
WO2013109906A2 (en) 2013-07-25
CA2862836A1 (en) 2013-07-25

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Legal Events

Date Code Title Description
PUAI Public reference made under article 153(3) epc to a published international application that has entered the european phase

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17P Request for examination filed

Effective date: 20140711

AK Designated contracting states

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Designated state(s): AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR

DAX Request for extension of the european patent (deleted)
A4 Supplementary search report drawn up and despatched

Effective date: 20150804

RIC1 Information provided on ipc code assigned before grant

Ipc: A61P 21/00 20060101ALI20150729BHEP

Ipc: A61K 9/20 20060101ALI20150729BHEP

Ipc: A61K 9/22 20060101ALI20150729BHEP

Ipc: A61K 31/7012 20060101AFI20150729BHEP

STAA Information on the status of an ep patent application or granted ep patent

Free format text: STATUS: THE APPLICATION HAS BEEN WITHDRAWN

18W Application withdrawn

Effective date: 20180112