DK1229040T3 - Nukleosid-monophosphatderivater, en fremgangsmåde til fremstilling deraf og anvendelse deraf som immunosuppressive lægemidler - Google Patents

Nukleosid-monophosphatderivater, en fremgangsmåde til fremstilling deraf og anvendelse deraf som immunosuppressive lægemidler

Info

Publication number
DK1229040T3
DK1229040T3 DK02008360T DK02008360T DK1229040T3 DK 1229040 T3 DK1229040 T3 DK 1229040T3 DK 02008360 T DK02008360 T DK 02008360T DK 02008360 T DK02008360 T DK 02008360T DK 1229040 T3 DK1229040 T3 DK 1229040T3
Authority
DK
Denmark
Prior art keywords
desoxy
preparation
chain
nucleoside monophosphate
monophosphate derivatives
Prior art date
Application number
DK02008360T
Other languages
English (en)
Inventor
Dieter Herrmann
Harald Zilch
Alfred Mertens
Original Assignee
Heidelberg Pharma Holding Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Heidelberg Pharma Holding Gmbh filed Critical Heidelberg Pharma Holding Gmbh
Application granted granted Critical
Publication of DK1229040T3 publication Critical patent/DK1229040T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/06—Pyrimidine radicals
    • C07H19/10—Pyrimidine radicals with the saccharide radical esterified by phosphoric or polyphosphoric acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/16—Purine radicals
    • C07H19/20—Purine radicals with the saccharide radical esterified by phosphoric or polyphosphoric acids

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Oncology (AREA)
  • Hematology (AREA)
  • Transplantation (AREA)
  • Virology (AREA)
  • Communicable Diseases (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
DK02008360T 1994-05-28 1995-05-23 Nukleosid-monophosphatderivater, en fremgangsmåde til fremstilling deraf og anvendelse deraf som immunosuppressive lægemidler DK1229040T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE4418690A DE4418690A1 (de) 1994-05-28 1994-05-28 Neue Lipidester von Nucleosid-Monophosphaten und deren Verwendung als immunsuppressive Arzneimittel

Publications (1)

Publication Number Publication Date
DK1229040T3 true DK1229040T3 (da) 2003-12-22

Family

ID=6519215

Family Applications (2)

Application Number Title Priority Date Filing Date
DK02008360T DK1229040T3 (da) 1994-05-28 1995-05-23 Nukleosid-monophosphatderivater, en fremgangsmåde til fremstilling deraf og anvendelse deraf som immunosuppressive lægemidler
DK95920864T DK0763049T3 (da) 1994-05-28 1995-05-23 Nukleosid-monophosphatderivater, fremgangsmåde til fremstilling heraf og anvendelse heraf som immunundertrykkende lægemidler

Family Applications After (1)

Application Number Title Priority Date Filing Date
DK95920864T DK0763049T3 (da) 1994-05-28 1995-05-23 Nukleosid-monophosphatderivater, fremgangsmåde til fremstilling heraf og anvendelse heraf som immunundertrykkende lægemidler

Country Status (27)

Country Link
US (1) US6025343A (da)
EP (2) EP0763049B1 (da)
JP (1) JP3802057B2 (da)
KR (1) KR100279087B1 (da)
CN (1) CN1168735C (da)
AT (2) ATE236189T1 (da)
AU (1) AU688516B2 (da)
BR (1) BR9507785A (da)
CA (1) CA2190983C (da)
CZ (1) CZ291846B6 (da)
DE (3) DE4418690A1 (da)
DK (2) DK1229040T3 (da)
ES (2) ES2199250T3 (da)
FI (1) FI117673B (da)
HU (1) HU220336B (da)
IL (1) IL113865A (da)
MX (1) MX9605809A (da)
NO (1) NO308998B1 (da)
NZ (1) NZ287434A (da)
PL (1) PL185290B1 (da)
PT (2) PT763049E (da)
RU (1) RU2165429C2 (da)
SK (1) SK284207B6 (da)
TW (1) TW420686B (da)
UA (1) UA45339C2 (da)
WO (1) WO1995032984A1 (da)
ZA (1) ZA954374B (da)

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Also Published As

Publication number Publication date
ES2199250T3 (es) 2004-02-16
ZA954374B (en) 1996-11-29
AU688516B2 (en) 1998-03-12
BR9507785A (pt) 1997-09-23
WO1995032984A1 (en) 1995-12-07
HU9603269D0 (en) 1997-01-28
DE69531749D1 (de) 2003-10-16
NO308998B1 (no) 2000-11-27
CN1168735C (zh) 2004-09-29
DK0763049T3 (da) 2003-07-28
JP3802057B2 (ja) 2006-07-26
CA2190983C (en) 2006-08-15
ATE236189T1 (de) 2003-04-15
IL113865A0 (en) 1995-08-31
EP1229040A2 (en) 2002-08-07
EP1229040A3 (en) 2002-08-21
CZ347796A3 (en) 1997-04-16
EP1229040B8 (en) 2003-11-05
ES2206429T3 (es) 2004-05-16
NO965054D0 (no) 1996-11-27
SK151896A3 (en) 1997-06-04
FI964727A0 (fi) 1996-11-27
IL113865A (en) 2008-12-29
UA45339C2 (uk) 2002-04-15
EP0763049B1 (en) 2003-04-02
KR970703354A (ko) 1997-07-03
TW420686B (en) 2001-02-01
KR100279087B1 (ko) 2001-01-15
ATE249472T1 (de) 2003-09-15
DE4418690A1 (de) 1996-01-11
CZ291846B6 (cs) 2003-06-18
JPH10500964A (ja) 1998-01-27
HU220336B (hu) 2001-12-28
DE69530197D1 (de) 2003-05-08
SK284207B6 (en) 2004-11-03
CA2190983A1 (en) 1995-12-07
PT763049E (pt) 2003-08-29
NZ287434A (en) 1998-01-26
HUT75340A (en) 1997-05-28
NO965054L (no) 1997-01-28
EP1229040B1 (en) 2003-09-10
WO1995032984A8 (en) 2003-01-16
PT1229040E (pt) 2003-12-31
AU2615495A (en) 1995-12-21
DE69530197T2 (de) 2004-01-29
EP0763049A1 (en) 1997-03-19
PL317380A1 (en) 1997-04-01
FI964727A (fi) 1996-11-27
FI117673B (fi) 2007-01-15
MX9605809A (es) 1997-12-31
US6025343A (en) 2000-02-15
RU2165429C2 (ru) 2001-04-20
PL185290B1 (pl) 2003-04-30
DE69531749T2 (de) 2004-07-29
CN1154111A (zh) 1997-07-09

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