DE69635903D1 - Rekombinantes fusionsprotein mit wachstumshormon und serumalbumin - Google Patents

Rekombinantes fusionsprotein mit wachstumshormon und serumalbumin

Info

Publication number
DE69635903D1
DE69635903D1 DE69635903T DE69635903T DE69635903D1 DE 69635903 D1 DE69635903 D1 DE 69635903D1 DE 69635903 T DE69635903 T DE 69635903T DE 69635903 T DE69635903 T DE 69635903T DE 69635903 D1 DE69635903 D1 DE 69635903D1
Authority
DE
Germany
Prior art keywords
fusion protein
serum albumin
growth hormone
recombinant fusion
polynucleotide
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69635903T
Other languages
English (en)
Other versions
DE69635903T2 (de
Inventor
David James Ballance
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novozymes Biopharma DK AS
Original Assignee
Delta Biotechnology Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Delta Biotechnology Ltd filed Critical Delta Biotechnology Ltd
Publication of DE69635903D1 publication Critical patent/DE69635903D1/de
Application granted granted Critical
Publication of DE69635903T2 publication Critical patent/DE69635903T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/62—DNA sequences coding for fusion proteins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
    • A61K38/27—Growth hormone [GH], i.e. somatotropin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/06—Drugs for disorders of the endocrine system of the anterior pituitary hormones, e.g. TSH, ACTH, FSH, LH, PRL, GH
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/61—Growth hormone [GH], i.e. somatotropin
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/76—Albumins
    • C07K14/765—Serum albumin, e.g. HSA
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Endocrinology (AREA)
  • Medicinal Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Toxicology (AREA)
  • Biomedical Technology (AREA)
  • Immunology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Epidemiology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Diabetes (AREA)
  • Wood Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Microbiology (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Crystals, And After-Treatments Of Crystals (AREA)
DE69635903T 1995-12-30 1996-12-19 Rekombinantes fusionsprotein mit wachstumshormon und serumalbumin Expired - Lifetime DE69635903T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB9526733 1995-12-30
GBGB9526733.2A GB9526733D0 (en) 1995-12-30 1995-12-30 Fusion proteins
PCT/GB1996/003164 WO1997024445A1 (en) 1995-12-30 1996-12-19 Recombinant fusion proteins to growth hormone and serum albumin

Publications (2)

Publication Number Publication Date
DE69635903D1 true DE69635903D1 (de) 2006-05-04
DE69635903T2 DE69635903T2 (de) 2006-11-16

Family

ID=10786210

Family Applications (2)

Application Number Title Priority Date Filing Date
DE69637743T Expired - Lifetime DE69637743D1 (de) 1995-12-30 1996-12-19 Rekombinantes Fusionsprotein mit Wachstumshormon und Serumalbumin
DE69635903T Expired - Lifetime DE69635903T2 (de) 1995-12-30 1996-12-19 Rekombinantes fusionsprotein mit wachstumshormon und serumalbumin

Family Applications Before (1)

Application Number Title Priority Date Filing Date
DE69637743T Expired - Lifetime DE69637743D1 (de) 1995-12-30 1996-12-19 Rekombinantes Fusionsprotein mit Wachstumshormon und Serumalbumin

Country Status (15)

Country Link
US (3) US7045318B2 (de)
EP (2) EP0870039B1 (de)
JP (1) JP4063878B2 (de)
KR (1) KR19990076789A (de)
CN (2) CN1119421C (de)
AT (2) ATE413460T1 (de)
AU (1) AU715210B2 (de)
CA (1) CA2240292C (de)
DE (2) DE69637743D1 (de)
DK (2) DK1681304T3 (de)
ES (2) ES2264146T3 (de)
GB (1) GB9526733D0 (de)
HK (1) HK1066816A1 (de)
PT (2) PT870039E (de)
WO (1) WO1997024445A1 (de)

Families Citing this family (123)

* Cited by examiner, † Cited by third party
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WO2021075526A1 (ja) 2019-10-17 2021-04-22 Ｊｃｒファーマ株式会社 血清アルブミンと成長ホルモンの融合蛋白質の製造方法
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US7550432B2 (en) 2009-06-23
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