DE69233424T2 - Pharmazeutische Zusammensetzungen aus heterozyklischen Angiotensin-II antagonisten und öligen Substanzen zur oralen Verabreichung und deren Herstellungsverfahren - Google Patents

Pharmazeutische Zusammensetzungen aus heterozyklischen Angiotensin-II antagonisten und öligen Substanzen zur oralen Verabreichung und deren Herstellungsverfahren Download PDF

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Publication number
DE69233424T2
DE69233424T2 DE69233424T DE69233424T DE69233424T2 DE 69233424 T2 DE69233424 T2 DE 69233424T2 DE 69233424 T DE69233424 T DE 69233424T DE 69233424 T DE69233424 T DE 69233424T DE 69233424 T2 DE69233424 T2 DE 69233424T2
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DE
Germany
Prior art keywords
alcohol
polyoxyethylene
ethers
formula
alcohol ethers
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
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DE69233424T
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German (de)
English (en)
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DE69233424D1 (de
Inventor
Tadashi Ibaraki Makino
Yoshio Minato-ku Mizukami
Jun-Ichi Kikuta
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Takeda Pharmaceutical Co Ltd
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Takeda Chemical Industries Ltd
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First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=17938952&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DE69233424(T2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Takeda Chemical Industries Ltd filed Critical Takeda Chemical Industries Ltd
Publication of DE69233424D1 publication Critical patent/DE69233424D1/de
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Publication of DE69233424T2 publication Critical patent/DE69233424T2/de
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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/53—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with three nitrogens as the only ring hetero atoms, e.g. chlorazanil, melamine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/415—1,2-Diazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4164—1,3-Diazoles
    • A61K31/4184—1,3-Diazoles condensed with carbocyclic rings, e.g. benzimidazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2013—Organic compounds, e.g. phospholipids, fats
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2013—Organic compounds, e.g. phospholipids, fats
    • A61K9/2018—Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/2031—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, polyethylene oxide, poloxamers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Cosmetics (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Plural Heterocyclic Compounds (AREA)
DE69233424T 1991-11-20 1992-11-19 Pharmazeutische Zusammensetzungen aus heterozyklischen Angiotensin-II antagonisten und öligen Substanzen zur oralen Verabreichung und deren Herstellungsverfahren Expired - Lifetime DE69233424T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP30492491 1991-11-20
JP30492491 1991-11-20

Publications (2)

Publication Number Publication Date
DE69233424D1 DE69233424D1 (de) 2004-11-04
DE69233424T2 true DE69233424T2 (de) 2005-02-17

Family

ID=17938952

Family Applications (2)

Application Number Title Priority Date Filing Date
DE69221831T Expired - Lifetime DE69221831T2 (de) 1991-11-20 1992-11-19 Arzneimittel mit Angiotensin-II-antagonistische Wirkung
DE69233424T Expired - Lifetime DE69233424T2 (de) 1991-11-20 1992-11-19 Pharmazeutische Zusammensetzungen aus heterozyklischen Angiotensin-II antagonisten und öligen Substanzen zur oralen Verabreichung und deren Herstellungsverfahren

Family Applications Before (1)

Application Number Title Priority Date Filing Date
DE69221831T Expired - Lifetime DE69221831T2 (de) 1991-11-20 1992-11-19 Arzneimittel mit Angiotensin-II-antagonistische Wirkung

Country Status (18)

Country Link
US (1) US5534534A (enExample)
EP (3) EP0782852B1 (enExample)
KR (1) KR100256633B1 (enExample)
CN (1) CN1047518C (enExample)
AT (2) ATE277602T1 (enExample)
AU (1) AU659691B2 (enExample)
BR (1) BR1100336A (enExample)
CA (1) CA2083305C (enExample)
DE (2) DE69221831T2 (enExample)
DK (1) DK0546358T3 (enExample)
ES (1) ES2104797T3 (enExample)
FI (2) FI111604B (enExample)
GR (1) GR3025338T3 (enExample)
HU (1) HU211608A9 (enExample)
MX (1) MX9206634A (enExample)
NO (1) NO304408B1 (enExample)
NZ (1) NZ245175A (enExample)
TW (1) TW284688B (enExample)

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PE20130210A1 (es) * 2007-03-28 2013-03-11 Takeda Pharmaceutical Composicion farmaceutica solida que comprende un derivado de bencimidazol y un agente de control de ph
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ES2364011B1 (es) 2009-11-20 2013-01-24 Gp Pharm, S.A. Cápsulas de principios activos farmacéuticos y ésteres de ácidos grasos poliinsaturados para el tratamiento de enfermedades cardiovasculares.
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PL236001B1 (pl) 2012-12-21 2020-11-30 Adamed Spolka Z Ograniczona Odpowiedzialnoscia Złożona kompozycja farmaceutyczna zawierająca kandesartan cyleksetylu oraz amlodypinę, sposób jej wytwarzania oraz jednostkowa postać dawkowania zawierająca tę kompozycję
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Also Published As

Publication number Publication date
GR3025338T3 (en) 1998-02-27
DE69233424D1 (de) 2004-11-04
FI20030210A7 (fi) 2003-02-12
FI925270L (fi) 1993-05-21
EP1468683A2 (en) 2004-10-20
NO924417D0 (no) 1992-11-16
ATE157248T1 (de) 1997-09-15
EP0546358A3 (enExample) 1994-03-30
BR1100336A (pt) 2000-04-18
MX9206634A (es) 1993-05-31
AU659691B2 (en) 1995-05-25
TW284688B (enExample) 1996-09-01
CN1047518C (zh) 1999-12-22
AU2839192A (en) 1993-05-27
CA2083305C (en) 2003-12-09
FI111604B (fi) 2003-08-29
CN1072338A (zh) 1993-05-26
US5534534A (en) 1996-07-09
EP0782852A1 (en) 1997-07-09
FI20030210L (fi) 2003-02-12
EP0546358B1 (en) 1997-08-27
EP1468683A3 (en) 2012-06-06
EP0782852B1 (en) 2004-09-29
NO304408B1 (no) 1998-12-14
NZ245175A (en) 1994-07-26
CA2083305A1 (en) 1993-05-21
FI925270A0 (fi) 1992-11-19
DE69221831D1 (de) 1997-10-02
HU211608A9 (en) 1995-12-28
KR930009606A (ko) 1993-06-21
KR100256633B1 (ko) 2000-05-15
NO924417L (no) 1993-05-21
ATE277602T1 (de) 2004-10-15
DE69221831T2 (de) 1998-01-02
EP0546358A2 (en) 1993-06-16
DK0546358T3 (da) 1998-03-09
ES2104797T3 (es) 1997-10-16

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