ATE518526T1 - Neue pharmazeutische zusammensetzung mit candesartan-cilexetil als lipophile kristalline substanz - Google Patents

Neue pharmazeutische zusammensetzung mit candesartan-cilexetil als lipophile kristalline substanz

Info

Publication number
ATE518526T1
ATE518526T1 AT06700941T AT06700941T ATE518526T1 AT E518526 T1 ATE518526 T1 AT E518526T1 AT 06700941 T AT06700941 T AT 06700941T AT 06700941 T AT06700941 T AT 06700941T AT E518526 T1 ATE518526 T1 AT E518526T1
Authority
AT
Austria
Prior art keywords
cilexetil
candesartan
pharmaceutical composition
crystalline substance
new pharmaceutical
Prior art date
Application number
AT06700941T
Other languages
English (en)
Inventor
Zdenka Jerala-Strukelj
Igor Legen
Original Assignee
Lek Pharmaceuticals
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lek Pharmaceuticals filed Critical Lek Pharmaceuticals
Application granted granted Critical
Publication of ATE518526T1 publication Critical patent/ATE518526T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4164—1,3-Diazoles
    • A61K31/4184—1,3-Diazoles condensed with carbocyclic rings, e.g. benzimidazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
    • A61K31/5415—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame ortho- or peri-condensed with carbocyclic ring systems, e.g. phenothiazine, chlorpromazine, piroxicam
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
AT06700941T 2005-01-26 2006-01-24 Neue pharmazeutische zusammensetzung mit candesartan-cilexetil als lipophile kristalline substanz ATE518526T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
SI200500021 2005-01-26
PCT/EP2006/000587 WO2006079496A1 (en) 2005-01-26 2006-01-24 New pharmaceutical composition containing candesartan cilexetil as lipophilic crystalline substance

Publications (1)

Publication Number Publication Date
ATE518526T1 true ATE518526T1 (de) 2011-08-15

Family

ID=36035685

Family Applications (1)

Application Number Title Priority Date Filing Date
AT06700941T ATE518526T1 (de) 2005-01-26 2006-01-24 Neue pharmazeutische zusammensetzung mit candesartan-cilexetil als lipophile kristalline substanz

Country Status (9)

Country Link
US (1) US20080118564A1 (de)
EP (1) EP1843754B1 (de)
JP (1) JP2008528456A (de)
AT (1) ATE518526T1 (de)
DK (1) DK1843754T3 (de)
ES (1) ES2371145T3 (de)
PL (1) PL1843754T3 (de)
SI (1) SI1843754T1 (de)
WO (1) WO2006079496A1 (de)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP5063370B2 (ja) * 2005-06-27 2012-10-31 第一三共株式会社 湿式造粒製薬の調製方法
TWI494134B (zh) * 2006-06-20 2015-08-01 Siegfried Generics Int Ag 含有坎地沙坦酯的組成物、錠劑和顆粒及該錠劑的製造方法
WO2008045006A1 (en) * 2006-10-11 2008-04-17 Fako Ilaclari A. S. Formulations of candesartan
ES2301401B1 (es) * 2006-11-28 2009-06-08 Laboratorios Liconsa S.A. Composicion farmaceutica solida estabilizada de candesartan cilexetilo.
SI2165702T1 (sl) 2008-09-17 2012-05-31 Helm Ag Stabilni in z lahkoto raztopljeni sestavki kandesartan cileksetila pripravljeni z vlažno granulacijo
CN102415998A (zh) * 2010-09-28 2012-04-18 扬子江药业集团北京海燕药业有限公司 盐酸马尼地平固体分散体及其制备方法
JP2013224265A (ja) * 2012-04-19 2013-10-31 Asahi Kasei Chemicals Corp 打圧感受性薬物を含有する錠剤
JP6272328B2 (ja) 2012-12-05 2018-01-31 沢井製薬株式会社 カンデサルタンシレキセチル含有製剤
CN103006598B (zh) * 2012-12-31 2015-12-02 广州白云山天心制药股份有限公司 含氯化钠药物载体的降血压片剂
ES2768651T3 (es) 2013-04-25 2020-06-23 Kyorin Seiyaku Kk Composición farmacéutica sólida
JP5844929B1 (ja) * 2015-04-03 2016-01-20 共和薬品工業株式会社 カンデサルタンシレキセチル及びヒドロクロロチアジドを含む錠剤
EP3219309A1 (de) * 2016-03-17 2017-09-20 K.H.S. Pharma Holding GmbH Pharmazeutische zusammensetzung mit fixdosierungskombination von amlodipin, candesartan cilexetil und hydrochlorothiazid zur behandlung von bluthochdruck
CN110876726A (zh) * 2019-11-20 2020-03-13 白喜平 一种坎地沙坦酯制剂及其制备方法

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5196444A (en) * 1990-04-27 1993-03-23 Takeda Chemical Industries, Ltd. 1-(cyclohexyloxycarbonyloxy)ethyl 2-ethoxy-1-[[2'-(1H-tetrazol-5-yl)biphenyl-4-yl]methyl]benzimidazole-7-carboxylate and compositions and methods of pharmaceutical use thereof
TW284688B (de) * 1991-11-20 1996-09-01 Takeda Pharm Industry Co Ltd
CN1215338A (zh) * 1996-04-05 1999-04-28 武田药品工业株式会社 包含具有血管紧张素ⅱ拮抗活性的化合物的药物组合物
US6210710B1 (en) * 1997-04-28 2001-04-03 Hercules Incorporated Sustained release polymer blend for pharmaceutical applications
ES2237121T3 (es) * 1998-07-28 2005-07-16 Takeda Pharmaceutical Company Limited Preparacion solida disgregable rapidamente.
PL353199A1 (en) * 1999-08-30 2003-11-03 Aventis Pharma Deutschland Gmbh Use of inhibitors of the renin-angiotensin system in the prevention of cardiovascular events
DE10029201A1 (de) * 2000-06-19 2001-12-20 Basf Ag Verfahren zur Herstellung fester oraler Darreichungsformen mit retardierender Wirkstoffreisetzung
AU2001294192A1 (en) * 2000-10-06 2002-04-22 Takeda Chemical Industries Ltd. Solid preparations
ES2366430T3 (es) * 2001-06-20 2011-10-20 Takeda Pharmaceutical Company Limited Método para fabricar comprimidos.
AUPS236902A0 (en) * 2002-05-16 2002-06-13 Northern Sydney Area Health Service Composition and method for treating hypertension
US20040202730A1 (en) * 2003-04-08 2004-10-14 Robert Gow Rosmarinic acid composition

Also Published As

Publication number Publication date
EP1843754A1 (de) 2007-10-17
ES2371145T3 (es) 2011-12-27
SI1843754T1 (sl) 2011-12-30
DK1843754T3 (da) 2011-11-21
PL1843754T3 (pl) 2011-12-30
JP2008528456A (ja) 2008-07-31
US20080118564A1 (en) 2008-05-22
EP1843754B1 (de) 2011-08-03
WO2006079496A1 (en) 2006-08-03

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