DE60031286D1 - Polymere zusammensetzung zur lösung von schwer wasserlöslichen medikamenten und verfahren zu deren herstellung - Google Patents

Polymere zusammensetzung zur lösung von schwer wasserlöslichen medikamenten und verfahren zu deren herstellung

Info

Publication number
DE60031286D1
DE60031286D1 DE60031286T DE60031286T DE60031286D1 DE 60031286 D1 DE60031286 D1 DE 60031286D1 DE 60031286 T DE60031286 T DE 60031286T DE 60031286 T DE60031286 T DE 60031286T DE 60031286 D1 DE60031286 D1 DE 60031286D1
Authority
DE
Germany
Prior art keywords
production
polymeric composition
heavy water
soluble medicaments
composition
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60031286T
Other languages
English (en)
Other versions
DE60031286T2 (de
Inventor
Min-Hyo Seo
In-Ja Choi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Samyang Biopharmaceuticals Corp
Original Assignee
Samyang Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Samyang Corp filed Critical Samyang Corp
Publication of DE60031286D1 publication Critical patent/DE60031286D1/de
Application granted granted Critical
Publication of DE60031286T2 publication Critical patent/DE60031286T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L101/00—Compositions of unspecified macromolecular compounds
    • C08L101/12—Compositions of unspecified macromolecular compounds characterised by physical features, e.g. anisotropy, viscosity or electrical conductivity
    • C08L101/14—Compositions of unspecified macromolecular compounds characterised by physical features, e.g. anisotropy, viscosity or electrical conductivity the macromolecular compounds being water soluble or water swellable, e.g. aqueous gels
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
    • A61K9/1075—Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L71/00—Compositions of polyethers obtained by reactions forming an ether link in the main chain; Compositions of derivatives of such polymers
    • C08L71/02—Polyalkylene oxides
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L2203/00—Applications
    • C08L2203/02—Applications for biomedical use
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L2205/00—Polymer mixtures characterised by other features
    • C08L2205/05—Polymer mixtures characterised by other features containing polymer components which can react with one another
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L67/00—Compositions of polyesters obtained by reactions forming a carboxylic ester link in the main chain; Compositions of derivatives of such polymers
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L67/00—Compositions of polyesters obtained by reactions forming a carboxylic ester link in the main chain; Compositions of derivatives of such polymers
    • C08L67/04—Polyesters derived from hydroxycarboxylic acids, e.g. lactones
DE60031286T 1999-08-14 2000-08-10 Polymere zusammensetzung zur lösung von schwer wasserlöslichen medikamenten und verfahren zu deren herstellung Expired - Lifetime DE60031286T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
KR9933500 1999-08-14
KR1019990033500A KR100360827B1 (ko) 1999-08-14 1999-08-14 난용성 약물을 가용화하기 위한 고분자 조성물 및 그의 제조방법
PCT/KR2000/000885 WO2001012718A1 (en) 1999-08-14 2000-08-10 Polymeric composition for solubilizing poorly water soluble drugs and process for the preparation thereof

Publications (2)

Publication Number Publication Date
DE60031286D1 true DE60031286D1 (de) 2006-11-23
DE60031286T2 DE60031286T2 (de) 2007-05-24

Family

ID=19607214

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60031286T Expired - Lifetime DE60031286T2 (de) 1999-08-14 2000-08-10 Polymere zusammensetzung zur lösung von schwer wasserlöslichen medikamenten und verfahren zu deren herstellung

Country Status (13)

Country Link
US (1) US6616941B1 (de)
EP (1) EP1226212B1 (de)
JP (1) JP3363142B1 (de)
KR (1) KR100360827B1 (de)
CN (1) CN1164675C (de)
AT (1) ATE342306T1 (de)
AU (1) AU763154B2 (de)
CA (1) CA2381729C (de)
DE (1) DE60031286T2 (de)
ES (1) ES2269168T3 (de)
MX (1) MXPA02001527A (de)
NZ (1) NZ517036A (de)
WO (1) WO2001012718A1 (de)

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Also Published As

Publication number Publication date
MXPA02001527A (es) 2002-07-02
CN1370201A (zh) 2002-09-18
EP1226212A4 (de) 2005-01-12
AU6479200A (en) 2001-03-13
AU763154B2 (en) 2003-07-17
EP1226212A1 (de) 2002-07-31
ES2269168T3 (es) 2007-04-01
KR20010017804A (ko) 2001-03-05
CA2381729C (en) 2008-07-29
NZ517036A (en) 2003-07-25
US6616941B1 (en) 2003-09-09
ATE342306T1 (de) 2006-11-15
JP3363142B1 (ja) 2003-01-08
WO2001012718A1 (en) 2001-02-22
EP1226212B1 (de) 2006-10-11
DE60031286T2 (de) 2007-05-24
JP2003507514A (ja) 2003-02-25
CA2381729A1 (en) 2001-02-22
CN1164675C (zh) 2004-09-01
KR100360827B1 (ko) 2002-11-18

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