BRPI0410956A - pelìculas com base em óxido de polietileno e sistemas de liberação de droga feitos delas - Google Patents
pelìculas com base em óxido de polietileno e sistemas de liberação de droga feitos delasInfo
- Publication number
- BRPI0410956A BRPI0410956A BRPI0410956-2A BRPI0410956A BRPI0410956A BR PI0410956 A BRPI0410956 A BR PI0410956A BR PI0410956 A BRPI0410956 A BR PI0410956A BR PI0410956 A BRPI0410956 A BR PI0410956A
- Authority
- BR
- Brazil
- Prior art keywords
- films
- polyethylene oxide
- active agent
- film
- systems made
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
- A61K9/0056—Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
- A61K9/006—Oral mucosa, e.g. mucoadhesive forms, sublingual droplets; Buccal patches or films; Buccal sprays
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08J—WORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
- C08J5/00—Manufacture of articles or shaped materials containing macromolecular substances
- C08J5/18—Manufacture of films or sheets
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
- C08L71/00—Compositions of polyethers obtained by reactions forming an ether link in the main chain; Compositions of derivatives of such polymers
- C08L71/02—Polyalkylene oxides
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08J—WORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
- C08J2371/00—Characterised by the use of polyethers obtained by reactions forming an ether link in the main chain; Derivatives of such polymers
- C08J2371/02—Polyalkylene oxides
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Manufacturing & Machinery (AREA)
- Epidemiology (AREA)
- Polymers & Plastics (AREA)
- Nutrition Science (AREA)
- Physiology (AREA)
- Materials Engineering (AREA)
- Zoology (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Medicinal Preparation (AREA)
- Cosmetics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
"PELìCULAS COM BASE EM óXIDO DE POLIETILENO E SISTEMAS DE LIBERAçãO DE DROGA FEITOS DELAS". A invenção refere-se aos produtos de película e métodos de sua preparação que demonstram uma heterogeneidade uniforme não-auto-agregante. Desejavelmente, as películas desintegram-se em água e podem ser formadas por um processo de secagem controlada, ou outro processo que mantém a uniformidade requerida da película. As películas contêm um componente polímero, que inclui óxido de polietileno opcionalmente misturado com polímeros celulósicos hidrofílicos. Desejavelmente, as películas também contêm um agente ativo farmacêutico e/ou cosmético com não mais do que uma variação de 10% do agente ativo farmacêutico e/ou agente ativo cosmético por área unitária da película.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US47390203P | 2003-05-28 | 2003-05-28 | |
PCT/US2004/017076 WO2006031209A1 (en) | 2003-05-28 | 2004-05-28 | Polyethylene oxide-based films and drug delivery systems made therefrom |
Publications (1)
Publication Number | Publication Date |
---|---|
BRPI0410956A true BRPI0410956A (pt) | 2006-07-04 |
Family
ID=35811416
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BRPI0410956-2A BRPI0410956A (pt) | 2003-05-28 | 2004-05-28 | pelìculas com base em óxido de polietileno e sistemas de liberação de droga feitos delas |
Country Status (8)
Country | Link |
---|---|
EP (3) | EP2716284A3 (pt) |
JP (1) | JP4795962B2 (pt) |
CN (2) | CN102670568A (pt) |
AU (2) | AU2004319243B2 (pt) |
BR (1) | BRPI0410956A (pt) |
CA (1) | CA2544776C (pt) |
NO (1) | NO20056060L (pt) |
WO (1) | WO2006031209A1 (pt) |
Families Citing this family (67)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2003024430A1 (en) | 2001-09-21 | 2003-03-27 | Egalet A/S | Morphine polymer release system |
EP1429739A1 (en) | 2001-09-21 | 2004-06-23 | Egalet A/S | Polymer release system |
US8900497B2 (en) | 2001-10-12 | 2014-12-02 | Monosol Rx, Llc | Process for making a film having a substantially uniform distribution of components |
US8765167B2 (en) | 2001-10-12 | 2014-07-01 | Monosol Rx, Llc | Uniform films for rapid-dissolve dosage form incorporating anti-tacking compositions |
US20190328679A1 (en) | 2001-10-12 | 2019-10-31 | Aquestive Therapeutics, Inc. | Uniform films for rapid-dissolve dosage form incorporating anti-tacking compositions |
US8603514B2 (en) | 2002-04-11 | 2013-12-10 | Monosol Rx, Llc | Uniform films for rapid dissolve dosage form incorporating taste-masking compositions |
US20080050422A1 (en) * | 2001-10-12 | 2008-02-28 | Monosolrx, Llc. | Method of administering a film product containing a drug |
US11207805B2 (en) | 2001-10-12 | 2021-12-28 | Aquestive Therapeutics, Inc. | Process for manufacturing a resulting pharmaceutical film |
US20110033542A1 (en) | 2009-08-07 | 2011-02-10 | Monosol Rx, Llc | Sublingual and buccal film compositions |
US8900498B2 (en) | 2001-10-12 | 2014-12-02 | Monosol Rx, Llc | Process for manufacturing a resulting multi-layer pharmaceutical film |
US10285910B2 (en) | 2001-10-12 | 2019-05-14 | Aquestive Therapeutics, Inc. | Sublingual and buccal film compositions |
US20070281003A1 (en) | 2001-10-12 | 2007-12-06 | Fuisz Richard C | Polymer-Based Films and Drug Delivery Systems Made Therefrom |
US7357891B2 (en) | 2001-10-12 | 2008-04-15 | Monosol Rx, Llc | Process for making an ingestible film |
ATE495732T1 (de) | 2003-03-26 | 2011-02-15 | Egalet As | Morphin-system mit kontrollierter freisetzung |
JP5160229B2 (ja) * | 2004-09-30 | 2013-03-13 | モノソル・アールエックス・エルエルシー | 均一の成分を有する多層フィルム |
WO2008028047A2 (en) * | 2006-08-30 | 2008-03-06 | Lab International Srl | Bioadhesive film drug delivery system |
JP4739452B2 (ja) * | 2006-09-20 | 2011-08-03 | モノソル アールエックス リミテッド ライアビリティ カンパニー | 発泡を減じる風味付与剤を含む喫食可能な水溶性フィルム |
AU2007304425B2 (en) | 2006-10-02 | 2013-12-05 | Spepharma Ag | Non-mucoadhesive film dosage forms |
WO2008089151A2 (en) * | 2007-01-12 | 2008-07-24 | Monosol Rx, Llc | High dose film compositions and methods of preparation |
US20080292683A1 (en) * | 2007-05-24 | 2008-11-27 | Monosolrx, Llc. | Film shreds and delivery system incorporating same |
AU2008258596B2 (en) | 2007-06-04 | 2013-02-14 | Egalet Ltd | Controlled release pharmaceutical compositions for prolonged effect |
US8298583B2 (en) * | 2007-10-19 | 2012-10-30 | Monosol Rx, Llc | Film delivery system for tetrahydrolipstatin |
WO2010002418A2 (en) * | 2008-07-01 | 2010-01-07 | The Johns Hopkins University | Quick-dissolving oral thin film for targeted delivery of therapeutic agents |
WO2010086989A1 (ja) | 2009-01-29 | 2010-08-05 | 日東電工株式会社 | 口腔内フィルム状基剤及び製剤 |
AU2010211220B2 (en) | 2009-02-06 | 2013-08-01 | Egalet Ltd. | Immediate release composition resistant to abuse by intake of alcohol |
PL2952191T3 (pl) | 2009-06-12 | 2019-02-28 | Sunovion Pharmaceuticals Inc. | Apomorfina w postaci do podawania podjęzykowego |
NZ603579A (en) | 2009-06-24 | 2014-02-28 | Egalet Ltd | Controlled release formulations |
KR101612073B1 (ko) | 2009-10-30 | 2016-04-14 | 아이엑스 바이오파마 리미티드 | 신속 용해 고체 투약 제형 |
JP5588688B2 (ja) | 2010-01-28 | 2014-09-10 | 日東電工株式会社 | フィルム状製剤 |
US8577488B2 (en) | 2010-02-11 | 2013-11-05 | Monosol Rx, Llc | Method and system for optimizing film production and minimizing film scrap |
US20110236666A1 (en) * | 2010-03-26 | 2011-09-29 | Hall Mark J | Melt-extruded film |
JP5751868B2 (ja) | 2010-03-30 | 2015-07-22 | 日東電工株式会社 | フィルム状製剤及びその製造方法 |
JP5800527B2 (ja) * | 2010-03-30 | 2015-10-28 | 日東電工株式会社 | 安定化医薬組成物、安定化医薬組成物溶液製剤、フィルム状製剤及びフィルム状製剤の製造方法 |
US9149959B2 (en) | 2010-10-22 | 2015-10-06 | Monosol Rx, Llc | Manufacturing of small film strips |
US20120107402A1 (en) * | 2010-10-29 | 2012-05-03 | Monosol Rx, Llc | Process for analyzing and establishing dosage size in an ingestible film |
NZ612686A (en) | 2010-12-16 | 2015-11-27 | Cynapsus Therapeutics Inc | Sublingual films |
JP5841433B2 (ja) | 2012-01-11 | 2016-01-13 | 日東電工株式会社 | 口腔内フィルム状基剤及び製剤 |
KR20150059167A (ko) | 2012-07-06 | 2015-05-29 | 에갈렛 리미티드 | 제어된 방출을 위한 남용 제지 약학적 조성물 |
WO2014176449A1 (en) * | 2013-04-25 | 2014-10-30 | Rinsenergy LLC | Oral rinse composition and method to deliver energy supplements |
US10226450B2 (en) | 2014-09-25 | 2019-03-12 | Shilpa Medicare Limited | Pharmaceutical film composition |
US20160220480A1 (en) * | 2015-02-03 | 2016-08-04 | Intelgenx Corp. | Oral dosage film exhibiting enhanced mucosal penetration |
EP3072502B1 (en) * | 2015-03-25 | 2020-07-08 | Universitätsmedizin der Johannes Gutenberg-Universität Mainz | Rheological blood replacement solution and uses thereof |
CA3127926A1 (en) | 2015-04-21 | 2016-10-27 | Sunovion Pharmaceuticals Inc. | Methods of treating parkinson's disease by administration of apomorphine to an oral mucosa |
US11273131B2 (en) | 2016-05-05 | 2022-03-15 | Aquestive Therapeutics, Inc. | Pharmaceutical compositions with enhanced permeation |
WO2017192921A1 (en) | 2016-05-05 | 2017-11-09 | Monosol Rx, Llc | Enhanced delivery epinephrine compositions |
MX2018013905A (es) * | 2016-05-13 | 2019-06-24 | Univ Guelph | Composiciones para la liberacion controlada de compuestos volatiles. |
EP4368169A2 (en) | 2016-12-31 | 2024-05-15 | Bioxcel Therapeutics, Inc. | Use of sublingual dexmedetomidine for the treatment of agitation |
US10799431B2 (en) * | 2017-01-09 | 2020-10-13 | The Procter & Gamble Company | Barrier patch with soluble film and methods of improving skin appearance |
DE102017103346A1 (de) * | 2017-02-17 | 2018-08-23 | Lts Lohmann Therapie-Systeme Ag | Strukturierte orodispergierbare Filme |
US11096892B2 (en) * | 2017-03-13 | 2021-08-24 | Nano And Advanced Materials Institute Limited | High loading and fast disintegration film for fast drug absorption |
DE102017112527B4 (de) * | 2017-06-07 | 2019-01-03 | Lts Lohmann Therapie-Systeme Ag | Schnell zerfallende Schaumwafer mit hohem Flächengewicht |
CN107325332B (zh) * | 2017-07-07 | 2018-10-26 | 许辉良 | 速溶羟丙基甲基纤维素及其制备方法 |
SG11202012772XA (en) | 2018-06-27 | 2021-01-28 | Bioxcel Therapeutics Inc | Film formulations containing dexmedetomidine and methods of producing them |
CN109382996B (zh) * | 2018-12-05 | 2024-04-30 | 无锡会通轻质材料股份有限公司 | 一种中空epp珠粒挤出机构 |
AU2020266590A1 (en) * | 2019-05-02 | 2021-12-16 | TearClear Corp. | Preservative removal from eye drops |
KR20220049526A (ko) | 2019-07-19 | 2022-04-21 | 바이오엑셀 테라퓨틱스 인코포레이티드 | 비-진정성 덱스메데토미딘 치료 양생법 |
CN111238199A (zh) * | 2020-01-16 | 2020-06-05 | 肇庆方兴包装材料有限公司 | 一种解决薄膜之间粘连的生产工艺及薄膜用烘干装置 |
EP3895692A1 (en) * | 2020-04-15 | 2021-10-20 | LTS Lohmann Therapie-Systeme AG | Oral thin film with smooth fused film |
CN111592670A (zh) * | 2020-06-24 | 2020-08-28 | 上海应用技术大学 | γ-聚谷氨酸分子印迹聚合物膜的制备方法 |
CN112472593B (zh) * | 2020-11-24 | 2022-06-10 | 牡丹江医学院 | 一种加入甜味剂掩盖苦味的口腔溃疡药膜加工设备 |
CN114230840A (zh) * | 2022-01-28 | 2022-03-25 | 孙琇芳 | 一种水溶可控型聚乙烯醇薄膜 |
CN114410044A (zh) * | 2022-01-28 | 2022-04-29 | 孙琇芳 | 一种水溶型真空包装保鲜膜及其使用方法 |
CN114848612A (zh) * | 2022-04-28 | 2022-08-05 | 青岛博益特生物材料股份有限公司 | 一种片状材料覆膜工艺及其生产的覆膜片状材料 |
CN115414876A (zh) * | 2022-09-07 | 2022-12-02 | 天津科技大学 | 一种纤维素纳米纤丝凝胶的平板微波浓缩装置、方法和应用 |
CN116294531A (zh) * | 2023-01-05 | 2023-06-23 | 安徽腾远化工科技有限公司 | 一种氨基模塑料高效烘干设备 |
US11806334B1 (en) | 2023-01-12 | 2023-11-07 | Bioxcel Therapeutics, Inc. | Non-sedating dexmedetomidine treatment regimens |
CN116589019B (zh) * | 2023-05-26 | 2023-10-27 | 深圳市一号芯环保科技有限公司 | 一种长效缓释型杀菌及抗氧化功能滤芯材料及制备方法 |
Family Cites Families (23)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4136145A (en) | 1974-07-05 | 1979-01-23 | Schering Aktiengesellschaft | Medicament carriers in the form of film having active substance incorporated therein |
US4631837A (en) | 1985-05-31 | 1986-12-30 | Magoon Richard E | Method and apparatus for drying fruit pulp and the like |
EP0283474A1 (de) | 1985-10-09 | 1988-09-28 | Desitin Arzneimittel GmbH | Verfahren zur herstellung einer darreichungs- und dosierungsform für arzneimittelwirkstoffe, reagentien oder andere wirkstoffe |
US4764378A (en) * | 1986-02-10 | 1988-08-16 | Zetachron, Inc. | Buccal drug dosage form |
US4713243A (en) * | 1986-06-16 | 1987-12-15 | Johnson & Johnson Products, Inc. | Bioadhesive extruded film for intra-oral drug delivery and process |
DE3630603A1 (de) * | 1986-09-09 | 1988-03-10 | Desitin Arzneimittel Gmbh | Darreichungs- und dosierungsform fuer arzneimittelwirkstoffe, reagentien oder dergleichen sowie verfahren zu deren herstellung |
DE4018247A1 (de) | 1990-06-07 | 1991-12-12 | Lohmann Therapie Syst Lts | Herstellungsverfahren fuer schnellzerfallende folienfoermige darreichungsformen |
IT1249315B (it) * | 1991-05-23 | 1995-02-22 | Euroresearch Srl | Lamina di collageno non poroso per uso terapeutico, metodo ed apparecchiature per ottenerlo |
US5393528A (en) * | 1992-05-07 | 1995-02-28 | Staab; Robert J. | Dissolvable device for contraception or delivery of medication |
AU679937B2 (en) * | 1992-11-18 | 1997-07-17 | Johnson & Johnson Consumer Products, Inc. | Extrudable compositions for topical or transdermal drug delivery |
US20010006677A1 (en) * | 1996-10-29 | 2001-07-05 | Mcginity James W. | Effervescence polymeric film drug delivery system |
DE19646392A1 (de) | 1996-11-11 | 1998-05-14 | Lohmann Therapie Syst Lts | Zubereitung zur Anwendung in der Mundhöhle mit einer an der Schleimhaut haftklebenden, Pharmazeutika oder Kosmetika zur dosierten Abgabe enthaltenden Schicht |
US6153210A (en) * | 1997-08-14 | 2000-11-28 | Periodontix, Inc. | Use of locally delivered metal ions for treatment of periodontal disease |
US6072100A (en) * | 1998-01-28 | 2000-06-06 | Johnson & Johnson Consumer Products, Inc. | Extrudable compositions for topical or transdermal drug delivery |
US6281337B1 (en) | 1998-11-12 | 2001-08-28 | Schering Corporation | Methods for conversion of protein isoforms |
DE19960154A1 (de) * | 1999-12-14 | 2001-07-12 | Lohmann Therapie Syst Lts | Flache Arzneizubereitung zur transmucosalen Verabreichung von Oxycodon oder einem vergleichbaren Wirkstoff in der Mundhöhle, für die Anwendung in der Schmerztherapie und Suchttherapie |
KR20010057582A (ko) * | 1999-12-23 | 2001-07-04 | 미쉘 지. 멘지니 | 수용성 필름 제조방법 |
US7067116B1 (en) * | 2000-03-23 | 2006-06-27 | Warner-Lambert Company Llc | Fast dissolving orally consumable solid film containing a taste masking agent and pharmaceutically active agent at weight ratio of 1:3 to 3:1 |
US6375981B1 (en) * | 2000-06-01 | 2002-04-23 | A. E. Staley Manufacturing Co. | Modified starch as a replacement for gelatin in soft gel films and capsules |
US20030118653A1 (en) * | 2001-07-06 | 2003-06-26 | Lavipharm Laboratories Inc. | Quick dissolving oral mucosal drug delivery device with moisture barrier coating |
EP2332523B8 (en) * | 2001-10-12 | 2022-04-20 | Aquestive Therapeutics, Inc. | Uniform films for rapid dissolve dosage form incorporating taste-masking compositions |
CA2473967C (en) * | 2001-10-12 | 2011-06-14 | Monosolrx Llc | Thin film with non-self-aggregating uniform heterogeneity, process for their production and drug delivery systems made therefrom |
CA2514897C (en) * | 2003-01-30 | 2012-08-28 | Monosolrx Llc | Thin film with non-self-aggregating uniform heterogeneity and drug delivery systems made therefrom |
-
2004
- 2004-05-28 JP JP2006535323A patent/JP4795962B2/ja not_active Expired - Lifetime
- 2004-05-28 AU AU2004319243A patent/AU2004319243B2/en not_active Expired
- 2004-05-28 CN CN2012101343508A patent/CN102670568A/zh active Pending
- 2004-05-28 CN CN2004800178969A patent/CN1812773B/zh not_active Expired - Lifetime
- 2004-05-28 WO PCT/US2004/017076 patent/WO2006031209A1/en active Application Filing
- 2004-05-28 BR BRPI0410956-2A patent/BRPI0410956A/pt not_active Application Discontinuation
- 2004-05-28 CA CA2544776A patent/CA2544776C/en not_active Expired - Lifetime
- 2004-05-28 EP EP13189513.8A patent/EP2716284A3/en not_active Withdrawn
- 2004-05-28 EP EP17151005.0A patent/EP3210601A1/en not_active Withdrawn
- 2004-05-28 EP EP04753818A patent/EP1663178A1/en not_active Withdrawn
-
2005
- 2005-12-20 NO NO20056060A patent/NO20056060L/no not_active Application Discontinuation
-
2010
- 2010-09-02 AU AU2010214780A patent/AU2010214780A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
NO20056060L (no) | 2006-02-07 |
EP3210601A1 (en) | 2017-08-30 |
CN1812773B (zh) | 2012-06-27 |
CN1812773A (zh) | 2006-08-02 |
AU2004319243A1 (en) | 2006-01-12 |
AU2004319243A8 (en) | 2008-08-07 |
EP2716284A2 (en) | 2014-04-09 |
AU2004319243B2 (en) | 2010-06-03 |
EP1663178A1 (en) | 2006-06-07 |
AU2010214780A1 (en) | 2010-09-23 |
WO2006031209A1 (en) | 2006-03-23 |
EP2716284A3 (en) | 2014-11-05 |
CA2544776C (en) | 2014-04-15 |
JP2007500252A (ja) | 2007-01-11 |
CA2544776A1 (en) | 2006-03-23 |
CN102670568A (zh) | 2012-09-19 |
JP4795962B2 (ja) | 2011-10-19 |
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