NO20056060L - Polyetylenoksidbaserte filmer og legemiddelleveringssystemer fremstilt fra disse - Google Patents
Polyetylenoksidbaserte filmer og legemiddelleveringssystemer fremstilt fra disseInfo
- Publication number
- NO20056060L NO20056060L NO20056060A NO20056060A NO20056060L NO 20056060 L NO20056060 L NO 20056060L NO 20056060 A NO20056060 A NO 20056060A NO 20056060 A NO20056060 A NO 20056060A NO 20056060 L NO20056060 L NO 20056060L
- Authority
- NO
- Norway
- Prior art keywords
- polyethylene oxide
- films
- drug delivery
- delivery systems
- oxide based
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
- A61K9/0056—Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
- A61K9/006—Oral mucosa, e.g. mucoadhesive forms, sublingual droplets; Buccal patches or films; Buccal sprays
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08J—WORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
- C08J5/00—Manufacture of articles or shaped materials containing macromolecular substances
- C08J5/18—Manufacture of films or sheets
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
- C08L71/00—Compositions of polyethers obtained by reactions forming an ether link in the main chain; Compositions of derivatives of such polymers
- C08L71/02—Polyalkylene oxides
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08J—WORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
- C08J2371/00—Characterised by the use of polyethers obtained by reactions forming an ether link in the main chain; Derivatives of such polymers
- C08J2371/02—Polyalkylene oxides
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Polymers & Plastics (AREA)
- Nutrition Science (AREA)
- Physiology (AREA)
- Epidemiology (AREA)
- Manufacturing & Machinery (AREA)
- Engineering & Computer Science (AREA)
- Pain & Pain Management (AREA)
- Materials Engineering (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Rheumatology (AREA)
- Zoology (AREA)
- Medicinal Preparation (AREA)
- Cosmetics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Oppfinnelsen vedrører de filmprodukter og fremgangsmåter for disses preparering som demonstrerer en ikke-selvaggregerende ensartet heterogenitet. Helst desintegreres filmene i vann og de kan dannes ved en kontrollert tørkeprosess, eller annen prosess som opprettholder filmens påkrevde ensartethet. Filmene inneholder en polymerkomponent, som inkluderer polyetylenoksid valgfritt blandet med hydrofile celluloseholdige polymerer. Helst inneholder filmene også et farmasøytisk og/eller kosmetisk aktivt agens med ikke mer enn et 10% avvik av det aktive farmasøytiske agens og/eller kosmetiske aktive agens pr. enhet areal av filmen.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US47390203P | 2003-05-28 | 2003-05-28 | |
PCT/US2004/017076 WO2006031209A1 (en) | 2003-05-28 | 2004-05-28 | Polyethylene oxide-based films and drug delivery systems made therefrom |
Publications (1)
Publication Number | Publication Date |
---|---|
NO20056060L true NO20056060L (no) | 2006-02-07 |
Family
ID=35811416
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO20056060A NO20056060L (no) | 2003-05-28 | 2005-12-20 | Polyetylenoksidbaserte filmer og legemiddelleveringssystemer fremstilt fra disse |
Country Status (8)
Country | Link |
---|---|
EP (3) | EP1663178A1 (no) |
JP (1) | JP4795962B2 (no) |
CN (2) | CN1812773B (no) |
AU (2) | AU2004319243B2 (no) |
BR (1) | BRPI0410956A (no) |
CA (1) | CA2544776C (no) |
NO (1) | NO20056060L (no) |
WO (1) | WO2006031209A1 (no) |
Families Citing this family (66)
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EP2957281A1 (en) | 2001-09-21 | 2015-12-23 | Egalet Ltd. | Polymer release system |
US20040253310A1 (en) | 2001-09-21 | 2004-12-16 | Gina Fischer | Morphine polymer release system |
US20190328679A1 (en) | 2001-10-12 | 2019-10-31 | Aquestive Therapeutics, Inc. | Uniform films for rapid-dissolve dosage form incorporating anti-tacking compositions |
US7357891B2 (en) | 2001-10-12 | 2008-04-15 | Monosol Rx, Llc | Process for making an ingestible film |
US20110033542A1 (en) | 2009-08-07 | 2011-02-10 | Monosol Rx, Llc | Sublingual and buccal film compositions |
US20080050422A1 (en) * | 2001-10-12 | 2008-02-28 | Monosolrx, Llc. | Method of administering a film product containing a drug |
US10285910B2 (en) | 2001-10-12 | 2019-05-14 | Aquestive Therapeutics, Inc. | Sublingual and buccal film compositions |
US8603514B2 (en) | 2002-04-11 | 2013-12-10 | Monosol Rx, Llc | Uniform films for rapid dissolve dosage form incorporating taste-masking compositions |
US20070281003A1 (en) | 2001-10-12 | 2007-12-06 | Fuisz Richard C | Polymer-Based Films and Drug Delivery Systems Made Therefrom |
US8900497B2 (en) | 2001-10-12 | 2014-12-02 | Monosol Rx, Llc | Process for making a film having a substantially uniform distribution of components |
US8900498B2 (en) | 2001-10-12 | 2014-12-02 | Monosol Rx, Llc | Process for manufacturing a resulting multi-layer pharmaceutical film |
US8765167B2 (en) | 2001-10-12 | 2014-07-01 | Monosol Rx, Llc | Uniform films for rapid-dissolve dosage form incorporating anti-tacking compositions |
US11207805B2 (en) | 2001-10-12 | 2021-12-28 | Aquestive Therapeutics, Inc. | Process for manufacturing a resulting pharmaceutical film |
WO2004084868A1 (en) | 2003-03-26 | 2004-10-07 | Egalet A/S | Morphine controlled release system |
EP2335921A1 (en) * | 2004-09-30 | 2011-06-22 | MonoSolRX, LLC | Multi-layer films |
WO2008028047A2 (en) * | 2006-08-30 | 2008-03-06 | Lab International Srl | Bioadhesive film drug delivery system |
EP2063864A4 (en) * | 2006-09-20 | 2012-03-14 | Monosol Rx Llc | EDIBLE WATER-SOLUBLE FILM CONTAINING FLAVOR-REDUCING AGENT |
AU2007304425B2 (en) | 2006-10-02 | 2013-12-05 | Spepharma Ag | Non-mucoadhesive film dosage forms |
AU2008206362A1 (en) * | 2007-01-12 | 2008-07-24 | Monosol Rx Llc | High dose film compositions and methods of preparation |
US20080292683A1 (en) * | 2007-05-24 | 2008-11-27 | Monosolrx, Llc. | Film shreds and delivery system incorporating same |
CA2687192C (en) | 2007-06-04 | 2015-11-24 | Egalet A/S | Controlled release pharmaceutical compositions for prolonged effect |
US8298583B2 (en) * | 2007-10-19 | 2012-10-30 | Monosol Rx, Llc | Film delivery system for tetrahydrolipstatin |
WO2010002418A2 (en) * | 2008-07-01 | 2010-01-07 | The Johns Hopkins University | Quick-dissolving oral thin film for targeted delivery of therapeutic agents |
WO2010086989A1 (ja) | 2009-01-29 | 2010-08-05 | 日東電工株式会社 | 口腔内フィルム状基剤及び製剤 |
CA2751667C (en) | 2009-02-06 | 2016-12-13 | Egalet Ltd. | Immediate release composition resistant to abuse by intake of alcohol |
PT2952191T (pt) | 2009-06-12 | 2018-11-30 | Sunovion Pharmaceuticals Inc | Apomorfina sublingual |
NZ597283A (en) | 2009-06-24 | 2013-07-26 | Egalet Ltd | Controlled release formulations |
PL2493457T3 (pl) | 2009-10-30 | 2018-01-31 | Ix Biopharma Ltd | Szybko rozpuszczalna stała postać dawkowana |
JP5588688B2 (ja) | 2010-01-28 | 2014-09-10 | 日東電工株式会社 | フィルム状製剤 |
US8577488B2 (en) * | 2010-02-11 | 2013-11-05 | Monosol Rx, Llc | Method and system for optimizing film production and minimizing film scrap |
KR101837927B1 (ko) * | 2010-03-26 | 2018-03-13 | 다우 글로벌 테크놀로지스 엘엘씨 | 용융-압출된 필름 |
JP5800527B2 (ja) * | 2010-03-30 | 2015-10-28 | 日東電工株式会社 | 安定化医薬組成物、安定化医薬組成物溶液製剤、フィルム状製剤及びフィルム状製剤の製造方法 |
JP5751868B2 (ja) | 2010-03-30 | 2015-07-22 | 日東電工株式会社 | フィルム状製剤及びその製造方法 |
US9149959B2 (en) | 2010-10-22 | 2015-10-06 | Monosol Rx, Llc | Manufacturing of small film strips |
US20120107402A1 (en) * | 2010-10-29 | 2012-05-03 | Monosol Rx, Llc | Process for analyzing and establishing dosage size in an ingestible film |
AU2011343429B2 (en) | 2010-12-16 | 2016-10-20 | Sunovion Pharmaceuticals Inc. | Sublingual films |
JP5841433B2 (ja) | 2012-01-11 | 2016-01-13 | 日東電工株式会社 | 口腔内フィルム状基剤及び製剤 |
EA201590165A1 (ru) | 2012-07-06 | 2015-08-31 | Эгалет Лтд. | Сдерживающие злоупотребление фармацевтические композиции для контролируемого высвобождения |
WO2014176449A1 (en) * | 2013-04-25 | 2014-10-30 | Rinsenergy LLC | Oral rinse composition and method to deliver energy supplements |
US10226450B2 (en) | 2014-09-25 | 2019-03-12 | Shilpa Medicare Limited | Pharmaceutical film composition |
US20160220480A1 (en) * | 2015-02-03 | 2016-08-04 | Intelgenx Corp. | Oral dosage film exhibiting enhanced mucosal penetration |
ES2819549T3 (es) * | 2015-03-25 | 2021-04-16 | Univ Der Johannes Gutenberg Univ Mainz | Solución de reemplazo de sangre reológica y sus usos |
CA3127926A1 (en) | 2015-04-21 | 2016-10-27 | Sunovion Pharmaceuticals Inc. | Methods of treating parkinson's disease by administration of apomorphine to an oral mucosa |
US11273131B2 (en) | 2016-05-05 | 2022-03-15 | Aquestive Therapeutics, Inc. | Pharmaceutical compositions with enhanced permeation |
KR20190005199A (ko) | 2016-05-05 | 2019-01-15 | 어퀘스티브 테라퓨틱스, 아이엔씨. | 강화된 전달 에프네프린 조성물 |
US11013249B2 (en) * | 2016-05-13 | 2021-05-25 | University Of Guelph | Compositions for controlled release of volatile compounds |
EP4371554A2 (en) | 2016-12-31 | 2024-05-22 | BioXcel Therapeutics, Inc. | Use of sublingual dexmedetomidine for the treatment of agitation |
US10799431B2 (en) * | 2017-01-09 | 2020-10-13 | The Procter & Gamble Company | Barrier patch with soluble film and methods of improving skin appearance |
DE102017103346A1 (de) * | 2017-02-17 | 2018-08-23 | Lts Lohmann Therapie-Systeme Ag | Strukturierte orodispergierbare Filme |
US11096892B2 (en) * | 2017-03-13 | 2021-08-24 | Nano And Advanced Materials Institute Limited | High loading and fast disintegration film for fast drug absorption |
DE102017112527B4 (de) * | 2017-06-07 | 2019-01-03 | Lts Lohmann Therapie-Systeme Ag | Schnell zerfallende Schaumwafer mit hohem Flächengewicht |
CN107325332B (zh) * | 2017-07-07 | 2018-10-26 | 许辉良 | 速溶羟丙基甲基纤维素及其制备方法 |
CN114983980A (zh) | 2018-06-27 | 2022-09-02 | 比奥克斯塞尔医疗股份有限公司 | 含右美托咪定的膜制剂及其制造方法 |
CN109382996B (zh) * | 2018-12-05 | 2024-04-30 | 无锡会通轻质材料股份有限公司 | 一种中空epp珠粒挤出机构 |
KR20220005070A (ko) * | 2019-05-02 | 2022-01-12 | 티어클리어 코포레이션 | 점안제로부터의 보존제 제거 |
BR112022000992A2 (pt) | 2019-07-19 | 2022-06-14 | Arx Llc | Regimes de tratamento de dexmedetomidina não sedantes |
CN111238199A (zh) * | 2020-01-16 | 2020-06-05 | 肇庆方兴包装材料有限公司 | 一种解决薄膜之间粘连的生产工艺及薄膜用烘干装置 |
EP3895692A1 (en) * | 2020-04-15 | 2021-10-20 | LTS Lohmann Therapie-Systeme AG | Oral thin film with smooth fused film |
CN111592670A (zh) * | 2020-06-24 | 2020-08-28 | 上海应用技术大学 | γ-聚谷氨酸分子印迹聚合物膜的制备方法 |
CN112472593B (zh) * | 2020-11-24 | 2022-06-10 | 牡丹江医学院 | 一种加入甜味剂掩盖苦味的口腔溃疡药膜加工设备 |
CN114230840A (zh) * | 2022-01-28 | 2022-03-25 | 孙琇芳 | 一种水溶可控型聚乙烯醇薄膜 |
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CN114848612A (zh) * | 2022-04-28 | 2022-08-05 | 青岛博益特生物材料股份有限公司 | 一种片状材料覆膜工艺及其生产的覆膜片状材料 |
CN115414876A (zh) * | 2022-09-07 | 2022-12-02 | 天津科技大学 | 一种纤维素纳米纤丝凝胶的平板微波浓缩装置、方法和应用 |
CN116294531A (zh) * | 2023-01-05 | 2023-06-23 | 安徽腾远化工科技有限公司 | 一种氨基模塑料高效烘干设备 |
CN116589019B (zh) * | 2023-05-26 | 2023-10-27 | 深圳市一号芯环保科技有限公司 | 一种长效缓释型杀菌及抗氧化功能滤芯材料及制备方法 |
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US4136145A (en) | 1974-07-05 | 1979-01-23 | Schering Aktiengesellschaft | Medicament carriers in the form of film having active substance incorporated therein |
US4631837A (en) | 1985-05-31 | 1986-12-30 | Magoon Richard E | Method and apparatus for drying fruit pulp and the like |
AU6541786A (en) * | 1985-10-09 | 1987-05-05 | Desitin Arzneimittel Gmbh | Process for producing an administration or dosage form of drugs, reagents or other active ingredients |
US4764378A (en) * | 1986-02-10 | 1988-08-16 | Zetachron, Inc. | Buccal drug dosage form |
US4713243A (en) * | 1986-06-16 | 1987-12-15 | Johnson & Johnson Products, Inc. | Bioadhesive extruded film for intra-oral drug delivery and process |
DE3630603A1 (de) * | 1986-09-09 | 1988-03-10 | Desitin Arzneimittel Gmbh | Darreichungs- und dosierungsform fuer arzneimittelwirkstoffe, reagentien oder dergleichen sowie verfahren zu deren herstellung |
DE4018247A1 (de) | 1990-06-07 | 1991-12-12 | Lohmann Therapie Syst Lts | Herstellungsverfahren fuer schnellzerfallende folienfoermige darreichungsformen |
IT1249315B (it) * | 1991-05-23 | 1995-02-22 | Euroresearch Srl | Lamina di collageno non poroso per uso terapeutico, metodo ed apparecchiature per ottenerlo |
US5393528A (en) * | 1992-05-07 | 1995-02-28 | Staab; Robert J. | Dissolvable device for contraception or delivery of medication |
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US20010006677A1 (en) * | 1996-10-29 | 2001-07-05 | Mcginity James W. | Effervescence polymeric film drug delivery system |
DE19646392A1 (de) * | 1996-11-11 | 1998-05-14 | Lohmann Therapie Syst Lts | Zubereitung zur Anwendung in der Mundhöhle mit einer an der Schleimhaut haftklebenden, Pharmazeutika oder Kosmetika zur dosierten Abgabe enthaltenden Schicht |
US6153210A (en) * | 1997-08-14 | 2000-11-28 | Periodontix, Inc. | Use of locally delivered metal ions for treatment of periodontal disease |
US6072100A (en) * | 1998-01-28 | 2000-06-06 | Johnson & Johnson Consumer Products, Inc. | Extrudable compositions for topical or transdermal drug delivery |
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DE19960154A1 (de) * | 1999-12-14 | 2001-07-12 | Lohmann Therapie Syst Lts | Flache Arzneizubereitung zur transmucosalen Verabreichung von Oxycodon oder einem vergleichbaren Wirkstoff in der Mundhöhle, für die Anwendung in der Schmerztherapie und Suchttherapie |
JP2001341145A (ja) * | 1999-12-23 | 2001-12-11 | Johnson & Johnson Consumer Co Inc | 水溶性フィルムの製造方法 |
US7067116B1 (en) * | 2000-03-23 | 2006-06-27 | Warner-Lambert Company Llc | Fast dissolving orally consumable solid film containing a taste masking agent and pharmaceutically active agent at weight ratio of 1:3 to 3:1 |
US6375981B1 (en) * | 2000-06-01 | 2002-04-23 | A. E. Staley Manufacturing Co. | Modified starch as a replacement for gelatin in soft gel films and capsules |
US20030118653A1 (en) * | 2001-07-06 | 2003-06-26 | Lavipharm Laboratories Inc. | Quick dissolving oral mucosal drug delivery device with moisture barrier coating |
WO2003030882A1 (en) * | 2001-10-12 | 2003-04-17 | Kosmos Pharma | Thin film with non-self-aggregating uniform heterogeneity, process for their production and drug delivery systems made thereform |
WO2003030883A1 (en) * | 2001-10-12 | 2003-04-17 | Kosmos Pharma | Uniform films for rapid dissolve dosage form incorporating taste-masking compositions |
CN100356908C (zh) * | 2003-01-30 | 2007-12-26 | 莫诺索尔克斯有限公司 | 具有非自聚集一致不均匀性的薄膜及由其制造的给药系统 |
-
2004
- 2004-05-28 WO PCT/US2004/017076 patent/WO2006031209A1/en active Application Filing
- 2004-05-28 CA CA2544776A patent/CA2544776C/en not_active Expired - Lifetime
- 2004-05-28 CN CN2004800178969A patent/CN1812773B/zh not_active Expired - Lifetime
- 2004-05-28 AU AU2004319243A patent/AU2004319243B2/en not_active Expired
- 2004-05-28 BR BRPI0410956-2A patent/BRPI0410956A/pt not_active Application Discontinuation
- 2004-05-28 CN CN2012101343508A patent/CN102670568A/zh active Pending
- 2004-05-28 JP JP2006535323A patent/JP4795962B2/ja not_active Expired - Lifetime
- 2004-05-28 EP EP04753818A patent/EP1663178A1/en not_active Withdrawn
- 2004-05-28 EP EP17151005.0A patent/EP3210601A1/en not_active Withdrawn
- 2004-05-28 EP EP13189513.8A patent/EP2716284A3/en not_active Withdrawn
-
2005
- 2005-12-20 NO NO20056060A patent/NO20056060L/no not_active Application Discontinuation
-
2010
- 2010-09-02 AU AU2010214780A patent/AU2010214780A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
AU2010214780A1 (en) | 2010-09-23 |
WO2006031209A1 (en) | 2006-03-23 |
EP3210601A1 (en) | 2017-08-30 |
CN1812773B (zh) | 2012-06-27 |
CA2544776C (en) | 2014-04-15 |
JP4795962B2 (ja) | 2011-10-19 |
AU2004319243A1 (en) | 2006-01-12 |
EP1663178A1 (en) | 2006-06-07 |
CN1812773A (zh) | 2006-08-02 |
AU2004319243A8 (en) | 2008-08-07 |
CN102670568A (zh) | 2012-09-19 |
JP2007500252A (ja) | 2007-01-11 |
AU2004319243B2 (en) | 2010-06-03 |
EP2716284A2 (en) | 2014-04-09 |
CA2544776A1 (en) | 2006-03-23 |
EP2716284A3 (en) | 2014-11-05 |
BRPI0410956A (pt) | 2006-07-04 |
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