DD297806A5 - Verfahren zur herstellung von n-methyl-3-(p-trifluormethylphenoxy)-3-phenylpropylamin - Google Patents

Verfahren zur herstellung von n-methyl-3-(p-trifluormethylphenoxy)-3-phenylpropylamin Download PDF

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Publication number
DD297806A5
DD297806A5 DD90338155A DD33815590A DD297806A5 DD 297806 A5 DD297806 A5 DD 297806A5 DD 90338155 A DD90338155 A DD 90338155A DD 33815590 A DD33815590 A DD 33815590A DD 297806 A5 DD297806 A5 DD 297806A5
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DD
German Democratic Republic
Prior art keywords
phenyl
formula
methyl
trifluoromethylphenoxy
fluoxetine
Prior art date
Application number
DD90338155A
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German (de)
English (en)
Inventor
Pekka J Kairisalo
Petri J Hukka
Anitta H Jaervinen
Original Assignee
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Publication of DD297806A5 publication Critical patent/DD297806A5/de

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C217/00—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton
    • C07C217/02—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C217/48—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being unsaturated and containing rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C213/00—Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton
    • C07C213/06—Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton from hydroxy amines by reactions involving the etherification or esterification of hydroxy groups

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Catalysts (AREA)
  • Indexing, Searching, Synchronizing, And The Amount Of Synchronization Travel Of Record Carriers (AREA)
  • Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
  • Jib Cranes (AREA)
DD90338155A 1989-03-03 1990-02-26 Verfahren zur herstellung von n-methyl-3-(p-trifluormethylphenoxy)-3-phenylpropylamin DD297806A5 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FI891015A FI81083C (fi) 1989-03-03 1989-03-03 Ett foerbaettrat foerfarande foer framstaellning av n-metyl-3-(p-trifluormetylfenoxi)-3-fenylpropylamin hydroklorid.

Publications (1)

Publication Number Publication Date
DD297806A5 true DD297806A5 (de) 1992-01-23

Family

ID=8527991

Family Applications (1)

Application Number Title Priority Date Filing Date
DD90338155A DD297806A5 (de) 1989-03-03 1990-02-26 Verfahren zur herstellung von n-methyl-3-(p-trifluormethylphenoxy)-3-phenylpropylamin

Country Status (24)

Country Link
EP (1) EP0391070B1 (sl)
JP (1) JPH0791244B2 (sl)
AT (1) ATE100440T1 (sl)
AU (1) AU620497B2 (sl)
BG (1) BG51156A3 (sl)
CA (1) CA2010410C (sl)
CS (1) CS276782B6 (sl)
DD (1) DD297806A5 (sl)
DE (1) DE69006072T2 (sl)
DK (2) DK172360B1 (sl)
ES (1) ES2062131T3 (sl)
FI (1) FI81083C (sl)
HR (1) HRP921278B1 (sl)
HU (1) HU204769B (sl)
IE (1) IE63650B1 (sl)
IL (1) IL92802A (sl)
NO (1) NO172284C (sl)
PL (1) PL163884B1 (sl)
PT (1) PT93302A (sl)
RO (1) RO105802B1 (sl)
RU (1) RU1779244C (sl)
SI (1) SI9010015B (sl)
YU (1) YU48249B (sl)
ZA (1) ZA90739B (sl)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1994000416A1 (en) * 1992-06-26 1994-01-06 Richter Gedeon Vegyészeti Gyár Rt. Preparation of n-methyl-3-phenyl-3-[4-(trifluoromethyl)phenoxy]propylamine and acid addition salts thereof

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL99316A (en) 1991-08-27 1995-03-15 Teva Pharma Production of fluoxetine and new intermediates
US5618968A (en) * 1993-02-05 1997-04-08 Pliva Farmaceutska Kemijska, Prehrambena I Kozmeticka Industrija, Dionicko Drustvo N-substituted derivatives of N-methyl-3-(p-trifluoromethylphenoxy)-3-phenylpropylamine and the procedure for their preparation
US5362886A (en) * 1993-10-12 1994-11-08 Eli Lilly And Company Asymmetric synthesis
ES2101650B1 (es) * 1995-06-29 1998-01-16 Lilly Sa Procedimiento de preparacion de n-metil-3-fenil-3-(p-trifluorometilfenoxi) propilamina.
ES2101654B1 (es) * 1995-07-24 1998-01-16 Lilly Sa Procedimiento de preparacion de n-metil-3-fenil-3-(p-trifluorometilfe noxi) propilamina.
ES2101655B1 (es) * 1995-07-28 1998-01-16 Lilly Sa Procedimiento de preparacion de n-metil-3-fenil-3-(p-trifluorometilfe noxi) propilamina.
ES2103680B1 (es) * 1995-08-03 1998-04-01 Lilly Sa Procedimiento de preparacion de n-metil-3-fenil-3- (p-trifluorometilfenoxi)propilamina.
ES2103681B1 (es) * 1995-09-19 1998-04-01 Lilly Sa Procedimiento de preparacion de n-metil-3-fenil - (p-trifluorometilfenoxi) propilamina.
ES2120368B1 (es) * 1996-06-14 1999-07-01 Almirall Prodesfarma Sa Procedimiento de obtencion de n-metil-3-(p-trifluorometilfenoxi)-3-fenilpropilamina y sus sales farmaceuticamente aceptables.
US6008412A (en) * 1997-10-14 1999-12-28 Eli Lilly And Company Process to make chiral compounds
TW514634B (en) * 1997-10-14 2002-12-21 Lilly Co Eli Process to make chiral compounds
US6025517A (en) * 1998-08-03 2000-02-15 Sepracor Inc. Fluoxetine process from benzoylacetonitrile
US6541668B1 (en) * 1999-04-09 2003-04-01 Eli Lilly And Company Methods for preparing 3-arloxy-3-arylpropylamines and intermediates thereof
US6313350B1 (en) 2001-01-31 2001-11-06 Grayson Walker Stowell Form a of fluoxetine hydrochloride
US6310251B1 (en) 2001-01-31 2001-10-30 Grayson Walker Stowell Form a of fluoxetine hydrochloride
US6316672B1 (en) 2001-01-31 2001-11-13 Grayson Walker Stowell Form a of fluoxetine hydrochloride
US6258853B1 (en) 2001-01-31 2001-07-10 Grayson Walker Stowell Form a of fluoxetine hydrochloride
US6310250B1 (en) 2001-01-31 2001-10-30 Grayson Walker Stowell Form A of fluoxetine hydrochloride
JP4769464B2 (ja) * 2005-01-12 2011-09-07 広栄化学工業株式会社 アルコール化合物の製造方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4314081A (en) * 1974-01-10 1982-02-02 Eli Lilly And Company Arloxyphenylpropylamines
GB2060618A (en) * 1979-09-14 1981-05-07 Wyeth John & Brother Ltd 3-Aryl-3-Aryloxypropylamines
JPS6172736A (ja) * 1984-09-18 1986-04-14 Toyo Soda Mfg Co Ltd エフエドリン誘導体およびその製造方法
GB8500482D0 (en) * 1985-01-09 1985-02-13 Shell Int Research Substituted phenyl ethers

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1994000416A1 (en) * 1992-06-26 1994-01-06 Richter Gedeon Vegyészeti Gyár Rt. Preparation of n-methyl-3-phenyl-3-[4-(trifluoromethyl)phenoxy]propylamine and acid addition salts thereof

Also Published As

Publication number Publication date
SI9010015B (sl) 1999-06-30
NO901013L (no) 1990-09-04
IE63650B1 (en) 1995-05-31
IE894118L (en) 1990-09-03
DK49790A (da) 1990-09-04
CS9001003A2 (en) 1991-09-15
FI81083C (fi) 1990-09-10
AU4996990A (en) 1990-09-06
EP0391070A1 (en) 1990-10-10
HU901276D0 (en) 1990-05-28
HRP921278B1 (en) 2000-04-30
EP0391070B1 (en) 1994-01-19
CS276782B6 (en) 1992-08-12
DK49790D0 (da) 1990-02-26
NO172284C (no) 1993-06-30
BG51156A3 (en) 1993-02-15
DE69006072D1 (de) 1994-03-03
YU1590A (en) 1991-10-31
PL163884B1 (pl) 1994-05-31
FI81083B (fi) 1990-05-31
JPH02282352A (ja) 1990-11-19
AU620497B2 (en) 1992-02-20
ES2062131T3 (es) 1994-12-16
FI891015A0 (fi) 1989-03-03
HRP921278A2 (en) 1995-08-31
YU48249B (sh) 1997-09-30
RU1779244C (ru) 1992-11-30
RO105802B1 (ro) 1992-12-30
ZA90739B (en) 1990-11-28
IL92802A (en) 1994-01-25
CA2010410C (en) 1997-03-18
CA2010410A1 (en) 1990-09-03
DK172360B1 (da) 1998-04-14
PT93302A (pt) 1990-11-07
ATE100440T1 (de) 1994-02-15
NO901013D0 (no) 1990-03-02
HUT54619A (en) 1991-03-28
JPH0791244B2 (ja) 1995-10-04
HU204769B (en) 1992-02-28
SI9010015A (sl) 1998-06-30
NO172284B (no) 1993-03-22
DE69006072T2 (de) 1994-06-30
DK0391070T3 (da) 1994-02-28

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IF04 In force in the year 2004

Expiry date: 20100227