DE69006072D1 - Verfahren zur Herstellung von N-Methyl-3-(p-Trifluoromethyl-phenoxy)-3-phenyl-propylamin und ihre Salze. - Google Patents

Verfahren zur Herstellung von N-Methyl-3-(p-Trifluoromethyl-phenoxy)-3-phenyl-propylamin und ihre Salze.

Info

Publication number
DE69006072D1
DE69006072D1 DE90104018T DE69006072T DE69006072D1 DE 69006072 D1 DE69006072 D1 DE 69006072D1 DE 90104018 T DE90104018 T DE 90104018T DE 69006072 T DE69006072 T DE 69006072T DE 69006072 D1 DE69006072 D1 DE 69006072D1
Authority
DE
Germany
Prior art keywords
phenyl
propylamine
chem
methyl
formula
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Revoked
Application number
DE90104018T
Other languages
English (en)
Other versions
DE69006072T2 (de
Inventor
Pekka Juhani Kairisalo
Petri Juhani Hukka
Anitta Hannele Jaervinen
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Orion Oyj
Original Assignee
Orion Yhtyma Oy
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=8527991&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DE69006072(D1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Orion Yhtyma Oy filed Critical Orion Yhtyma Oy
Publication of DE69006072D1 publication Critical patent/DE69006072D1/de
Application granted granted Critical
Publication of DE69006072T2 publication Critical patent/DE69006072T2/de
Anticipated expiration legal-status Critical
Revoked legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C217/00—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton
    • C07C217/02—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C217/48—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being unsaturated and containing rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C213/00—Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton
    • C07C213/06—Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton from hydroxy amines by reactions involving the etherification or esterification of hydroxy groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Catalysts (AREA)
  • Indexing, Searching, Synchronizing, And The Amount Of Synchronization Travel Of Record Carriers (AREA)
  • Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
  • Jib Cranes (AREA)
DE69006072T 1989-03-03 1990-03-01 Verfahren zur Herstellung von N-Methyl-3-(p-Trifluoromethyl-phenoxy)-3-phenyl-propylamin und ihre Salze. Revoked DE69006072T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FI891015A FI81083C (fi) 1989-03-03 1989-03-03 Ett foerbaettrat foerfarande foer framstaellning av n-metyl-3-(p-trifluormetylfenoxi)-3-fenylpropylamin hydroklorid.

Publications (2)

Publication Number Publication Date
DE69006072D1 true DE69006072D1 (de) 1994-03-03
DE69006072T2 DE69006072T2 (de) 1994-06-30

Family

ID=8527991

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69006072T Revoked DE69006072T2 (de) 1989-03-03 1990-03-01 Verfahren zur Herstellung von N-Methyl-3-(p-Trifluoromethyl-phenoxy)-3-phenyl-propylamin und ihre Salze.

Country Status (24)

Country Link
EP (1) EP0391070B1 (de)
JP (1) JPH0791244B2 (de)
AT (1) ATE100440T1 (de)
AU (1) AU620497B2 (de)
BG (1) BG51156A3 (de)
CA (1) CA2010410C (de)
CS (1) CS276782B6 (de)
DD (1) DD297806A5 (de)
DE (1) DE69006072T2 (de)
DK (2) DK172360B1 (de)
ES (1) ES2062131T3 (de)
FI (1) FI81083C (de)
HR (1) HRP921278B1 (de)
HU (1) HU204769B (de)
IE (1) IE63650B1 (de)
IL (1) IL92802A (de)
NO (1) NO172284C (de)
PL (1) PL163884B1 (de)
PT (1) PT93302A (de)
RO (1) RO105802B1 (de)
RU (1) RU1779244C (de)
SI (1) SI9010015B (de)
YU (1) YU48249B (de)
ZA (1) ZA90739B (de)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL99316A (en) 1991-08-27 1995-03-15 Teva Pharma Production of fluoxetine and new intermediates
HU9202128D0 (en) * 1992-06-26 1992-10-28 Richter Gedeon Vegyeszet Method for producing n-methyl-(3-phenyl-3-(4-[trifluoro-methyl])-phenooxi-)-amine
US5618968A (en) * 1993-02-05 1997-04-08 Pliva Farmaceutska Kemijska, Prehrambena I Kozmeticka Industrija, Dionicko Drustvo N-substituted derivatives of N-methyl-3-(p-trifluoromethylphenoxy)-3-phenylpropylamine and the procedure for their preparation
US5362886A (en) * 1993-10-12 1994-11-08 Eli Lilly And Company Asymmetric synthesis
ES2101650B1 (es) * 1995-06-29 1998-01-16 Lilly Sa Procedimiento de preparacion de n-metil-3-fenil-3-(p-trifluorometilfenoxi) propilamina.
ES2101654B1 (es) * 1995-07-24 1998-01-16 Lilly Sa Procedimiento de preparacion de n-metil-3-fenil-3-(p-trifluorometilfe noxi) propilamina.
ES2101655B1 (es) * 1995-07-28 1998-01-16 Lilly Sa Procedimiento de preparacion de n-metil-3-fenil-3-(p-trifluorometilfe noxi) propilamina.
ES2103680B1 (es) * 1995-08-03 1998-04-01 Lilly Sa Procedimiento de preparacion de n-metil-3-fenil-3- (p-trifluorometilfenoxi)propilamina.
ES2103681B1 (es) * 1995-09-19 1998-04-01 Lilly Sa Procedimiento de preparacion de n-metil-3-fenil - (p-trifluorometilfenoxi) propilamina.
ES2120368B1 (es) * 1996-06-14 1999-07-01 Almirall Prodesfarma Sa Procedimiento de obtencion de n-metil-3-(p-trifluorometilfenoxi)-3-fenilpropilamina y sus sales farmaceuticamente aceptables.
US6008412A (en) * 1997-10-14 1999-12-28 Eli Lilly And Company Process to make chiral compounds
TW514634B (en) * 1997-10-14 2002-12-21 Lilly Co Eli Process to make chiral compounds
US6025517A (en) * 1998-08-03 2000-02-15 Sepracor Inc. Fluoxetine process from benzoylacetonitrile
US6541668B1 (en) * 1999-04-09 2003-04-01 Eli Lilly And Company Methods for preparing 3-arloxy-3-arylpropylamines and intermediates thereof
US6313350B1 (en) 2001-01-31 2001-11-06 Grayson Walker Stowell Form a of fluoxetine hydrochloride
US6310251B1 (en) 2001-01-31 2001-10-30 Grayson Walker Stowell Form a of fluoxetine hydrochloride
US6316672B1 (en) 2001-01-31 2001-11-13 Grayson Walker Stowell Form a of fluoxetine hydrochloride
US6258853B1 (en) 2001-01-31 2001-07-10 Grayson Walker Stowell Form a of fluoxetine hydrochloride
US6310250B1 (en) 2001-01-31 2001-10-30 Grayson Walker Stowell Form A of fluoxetine hydrochloride
JP4769464B2 (ja) * 2005-01-12 2011-09-07 広栄化学工業株式会社 アルコール化合物の製造方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4314081A (en) * 1974-01-10 1982-02-02 Eli Lilly And Company Arloxyphenylpropylamines
GB2060618A (en) * 1979-09-14 1981-05-07 Wyeth John & Brother Ltd 3-Aryl-3-Aryloxypropylamines
JPS6172736A (ja) * 1984-09-18 1986-04-14 Toyo Soda Mfg Co Ltd エフエドリン誘導体およびその製造方法
GB8500482D0 (en) * 1985-01-09 1985-02-13 Shell Int Research Substituted phenyl ethers

Also Published As

Publication number Publication date
SI9010015B (sl) 1999-06-30
NO901013L (no) 1990-09-04
IE63650B1 (en) 1995-05-31
IE894118L (en) 1990-09-03
DK49790A (da) 1990-09-04
CS9001003A2 (en) 1991-09-15
FI81083C (fi) 1990-09-10
AU4996990A (en) 1990-09-06
EP0391070A1 (de) 1990-10-10
HU901276D0 (en) 1990-05-28
HRP921278B1 (en) 2000-04-30
EP0391070B1 (de) 1994-01-19
CS276782B6 (en) 1992-08-12
DK49790D0 (da) 1990-02-26
NO172284C (no) 1993-06-30
BG51156A3 (en) 1993-02-15
YU1590A (en) 1991-10-31
PL163884B1 (pl) 1994-05-31
FI81083B (fi) 1990-05-31
JPH02282352A (ja) 1990-11-19
AU620497B2 (en) 1992-02-20
DD297806A5 (de) 1992-01-23
ES2062131T3 (es) 1994-12-16
FI891015A0 (fi) 1989-03-03
HRP921278A2 (en) 1995-08-31
YU48249B (sh) 1997-09-30
RU1779244C (ru) 1992-11-30
RO105802B1 (ro) 1992-12-30
ZA90739B (en) 1990-11-28
IL92802A (en) 1994-01-25
CA2010410C (en) 1997-03-18
CA2010410A1 (en) 1990-09-03
DK172360B1 (da) 1998-04-14
PT93302A (pt) 1990-11-07
ATE100440T1 (de) 1994-02-15
NO901013D0 (no) 1990-03-02
HUT54619A (en) 1991-03-28
JPH0791244B2 (ja) 1995-10-04
HU204769B (en) 1992-02-28
SI9010015A (sl) 1998-06-30
NO172284B (no) 1993-03-22
DE69006072T2 (de) 1994-06-30
DK0391070T3 (da) 1994-02-28

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Legal Events

Date Code Title Description
8363 Opposition against the patent
8328 Change in the person/name/address of the agent

Free format text: BARZ, P., DIPL.-CHEM. DR.RER.NAT., PAT.-ANW., 80803 MUENCHEN

8331 Complete revocation