MX11031A - Proceso para la preparacion de nuevas 1-fenil-3-naftaleniloxipropanaminas producto obtenido y composicion farmaceutica que lo incluye. - Google Patents

Proceso para la preparacion de nuevas 1-fenil-3-naftaleniloxipropanaminas producto obtenido y composicion farmaceutica que lo incluye.

Info

Publication number
MX11031A
MX11031A MX1103188A MX1103188A MX11031A MX 11031 A MX11031 A MX 11031A MX 1103188 A MX1103188 A MX 1103188A MX 1103188 A MX1103188 A MX 1103188A MX 11031 A MX11031 A MX 11031A
Authority
MX
Mexico
Prior art keywords
phenyl
naphthalenyloxipropanamins
preparation
new
pharmaceutical composition
Prior art date
Application number
MX1103188A
Other languages
English (en)
Inventor
David Wayne Robertson
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of MX11031A publication Critical patent/MX11031A/es

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C217/00Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton
    • C07C217/02Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C217/48Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being unsaturated and containing rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D317/00Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D317/08Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
    • C07D317/44Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D317/46Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems condensed with one six-membered ring
    • C07D317/48Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring
    • C07D317/50Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to atoms of the carbocyclic ring
    • C07D317/58Radicals substituted by nitrogen atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/14Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/20Hypnotics; Sedatives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/30Drugs for disorders of the nervous system for treating abuse or dependence
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/04Anorexiants; Antiobesity agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Psychiatry (AREA)
  • Diabetes (AREA)
  • Pain & Pain Management (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Child & Adolescent Psychology (AREA)
  • Anesthesiology (AREA)
  • Addiction (AREA)
  • Hospice & Palliative Care (AREA)
  • Nutrition Science (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Compounds That Contain Two Or More Ring Oxygen Atoms (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
MX1103188A 1987-04-09 1988-04-07 Proceso para la preparacion de nuevas 1-fenil-3-naftaleniloxipropanaminas producto obtenido y composicion farmaceutica que lo incluye. MX11031A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US3653487A 1987-04-09 1987-04-09

Publications (1)

Publication Number Publication Date
MX11031A true MX11031A (es) 1993-11-01

Family

ID=21889125

Family Applications (1)

Application Number Title Priority Date Filing Date
MX1103188A MX11031A (es) 1987-04-09 1988-04-07 Proceso para la preparacion de nuevas 1-fenil-3-naftaleniloxipropanaminas producto obtenido y composicion farmaceutica que lo incluye.

Country Status (23)

Country Link
EP (1) EP0288188B1 (es)
JP (1) JPH0637443B2 (es)
KR (1) KR960007723B1 (es)
CN (1) CN1020093C (es)
AT (1) ATE68473T1 (es)
AU (1) AU602971B2 (es)
CA (1) CA1329937C (es)
CY (1) CY1658A (es)
DE (1) DE3865504D1 (es)
DK (1) DK170637B1 (es)
EG (1) EG18584A (es)
ES (1) ES2045109T3 (es)
GR (1) GR3003267T3 (es)
HK (1) HK63992A (es)
HU (1) HU204767B (es)
IL (1) IL85988A (es)
MX (1) MX11031A (es)
NZ (1) NZ224161A (es)
PH (1) PH27141A (es)
PT (1) PT87163B (es)
SG (1) SG67092G (es)
SU (1) SU1568886A3 (es)
ZA (1) ZA882418B (es)

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK258389D0 (da) * 1989-05-26 1989-05-26 Ferrosan As Aryloxyphenylpropylaminer, deres fremstilling og anvendelse
CA2061665C (en) * 1991-02-25 2002-04-16 Mark Mortensen Foreman Treatment of lower urinary tract disorders
WO1993013049A1 (fr) * 1991-12-20 1993-07-08 Karin Elisabeth Peuschel Emploi de l'effet immunoactivant de 3-naphthyloxy-2-hydroxy-propylamines, interessant specialement pour l'immunite cellulaire, par exemple contre infections virales
TW344661B (en) * 1993-11-24 1998-11-11 Lilly Co Eli Pharmaceutical composition for treatment of incontinence
DE69524962T4 (de) * 1994-08-22 2003-08-28 Mitsubishi Pharma Corp., Osaka Benzolderivate und deren medizinische verwendung
US5948820A (en) 1994-08-22 1999-09-07 Yoshitomi Pharmaceutical Industries, Ltd. Benzene compound and pharmaceutical use thereof
DE19956786A1 (de) * 1999-11-25 2001-05-31 Basf Ag Verfahren zur Herstellung optisch aktiver Amine
CN100402488C (zh) * 2006-03-15 2008-07-16 上海玛耀化学技术有限公司 一种达泊西汀的合成方法
WO2008035358A2 (en) * 2006-06-05 2008-03-27 Cadila Healthcare Limited Process for preparing dapoxetine
CN101367739B (zh) * 2008-09-24 2013-02-13 台州职业技术学院 N,n-二甲基-1-苯基-3-(1-萘氧基)丙胺制备工艺
DE102009015702A1 (de) 2009-03-31 2010-10-07 Ratiopharm Gmbh Tabletten enthaltend Dapoxetin und Trockenverarbeitungsverfahren zu deren Herstellung
EP2513042A4 (en) 2009-11-13 2013-06-26 Symed Labs Ltd DAPOXETIN SOLID
DE102009058321A1 (de) 2009-12-15 2011-06-16 Ratiopharm Gmbh Schmelztablette, enthaltend Dapoxetin
WO2011161690A1 (en) * 2010-06-23 2011-12-29 Symed Labs Limited Processes for the preparation of (+)-n,n-dimethyl-2-[1-(naphthalenyloxy) ethyl] benzene methanamine and intermediates thereof
CN102229538B (zh) * 2011-05-11 2013-11-13 中南大学 一种达泊西汀的合成方法
CN102850318A (zh) * 2011-07-01 2013-01-02 中国人民解放军军事医学科学院毒物药物研究所 新的选择性5-羟色胺重摄取抑制剂及其医药用途
CN103130660B (zh) * 2011-11-25 2014-09-17 厦门福满药业有限公司 一类达泊西汀的酸式盐及其晶体,以及晶体的制备方法
WO2013180675A1 (en) 2012-05-28 2013-12-05 Mahmut Bilgic Tablet formulation comprising dapoxetine
CN102746170A (zh) * 2012-07-28 2012-10-24 湖南尔文生物科技有限公司 一种达泊西汀的制备方法
WO2014027981A2 (en) 2012-08-17 2014-02-20 Sanovel Ilac Sanayi Ve Ticaret Anonim Sirketi Effervescent tablet formulations of dapoxetine and a pde5 inhibitor
WO2014027979A2 (en) 2012-08-17 2014-02-20 Sanovel Ilac Sanayi Ve Ticaret Anonim Sirketi Tablet formulations comprising tadalafil and dapoxetine
US20150202168A1 (en) 2012-08-17 2015-07-23 Sanovel llac Sanayi Ve Ticaret Anonim Sirketi Oral film formulations comprising dapoxetine and tadalafil
TR201309037A2 (tr) 2012-08-17 2014-03-21 Sanovel Ilac Sanayi Ve Ticaret Anonim Sirketi Dapoksetin ve bir pde5 inhibitörü içeren yeni efervesan saşe formülasyonları.
WO2014027982A2 (en) 2012-08-17 2014-02-20 Sanovel Ilac Sanayi Ve Ticaret Anonim Sirketi Novel effervescent sachet formulations of dapoxetine and a pde5 inhibitor
WO2014027975A2 (en) 2012-08-17 2014-02-20 Sanovel Ilac Sanayi Ve Ticaret Anonim Sirketi Novel orally administered pharmaceutical formulations
CN102942496B (zh) * 2012-11-28 2014-06-11 扬州工业职业技术学院 (s)-n,n-二甲基-3-(萘酚-1-氧基)-1-苯基丙基-1-胺的制备方法
EP2749553A1 (en) 2012-12-31 2014-07-02 Deva Holding Anonim Sirketi Process for preparation of enantiomerically pure S-(+)-N, N-dimethyl-a-[2-(naphthalenyloxy)ethyl] benzenemethanamine
CN106748825A (zh) * 2016-11-29 2017-05-31 聊城大学 一种达泊西汀的合成、拆分纯化和成盐方法
CN108853072A (zh) * 2018-08-03 2018-11-23 安徽省金楠医疗科技有限公司 一种盐酸达泊西汀片及其制备方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4018895A (en) * 1974-01-10 1977-04-19 Eli Lilly And Company Aryloxyphenylpropylamines in treating depression
US4207343A (en) * 1978-06-22 1980-06-10 Eli Lilly And Company 1-Phenyl-3-(substituted phenoxy)propylamines
NZ213651A (en) * 1984-10-11 1989-07-27 Hoffmann La Roche Tetrahydronapthalene derivatives and medicaments

Also Published As

Publication number Publication date
DK188288D0 (da) 1988-04-07
KR960007723B1 (ko) 1996-06-11
PT87163A (pt) 1988-05-01
CY1658A (en) 1993-05-14
ATE68473T1 (de) 1991-11-15
IL85988A0 (en) 1988-09-30
IL85988A (en) 1992-08-18
PT87163B (pt) 1992-07-31
HK63992A (en) 1992-08-28
GR3003267T3 (en) 1993-02-17
NZ224161A (en) 1990-04-26
EP0288188A1 (en) 1988-10-26
ZA882418B (en) 1989-12-27
JPH0637443B2 (ja) 1994-05-18
SU1568886A3 (ru) 1990-05-30
HU204767B (en) 1992-02-28
CA1329937C (en) 1994-05-31
AU1433588A (en) 1988-10-13
ES2045109T3 (es) 1994-01-16
KR880012526A (ko) 1988-11-28
CN88102018A (zh) 1988-10-26
CN1020093C (zh) 1993-03-17
PH27141A (en) 1993-04-02
DE3865504D1 (de) 1991-11-21
DK188288A (da) 1989-01-12
JPS63258837A (ja) 1988-10-26
AU602971B2 (en) 1990-11-01
EP0288188B1 (en) 1991-10-16
DK170637B1 (da) 1995-11-20
EG18584A (en) 1994-07-30
HUT50316A (en) 1990-01-29
SG67092G (en) 1992-09-04

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