BG51156A3 - Process for the preparation of n-methyl-3/p-trifluoromrthylphenoxy/-3-phenyl-propylamine hydrochloride - Google Patents
Process for the preparation of n-methyl-3/p-trifluoromrthylphenoxy/-3-phenyl-propylamine hydrochloride Download PDFInfo
- Publication number
- BG51156A3 BG51156A3 BG091247A BG9124790A BG51156A3 BG 51156 A3 BG51156 A3 BG 51156A3 BG 091247 A BG091247 A BG 091247A BG 9124790 A BG9124790 A BG 9124790A BG 51156 A3 BG51156 A3 BG 51156A3
- Authority
- BG
- Bulgaria
- Prior art keywords
- phenyl
- methyl
- trifluoromrthylphenoxy
- propylamine
- preparation
- Prior art date
Links
- GIYXAJPCNFJEHY-UHFFFAOYSA-N N-methyl-3-phenyl-3-[4-(trifluoromethyl)phenoxy]-1-propanamine hydrochloride (1:1) Chemical compound Cl.C=1C=CC=CC=1C(CCNC)OC1=CC=C(C(F)(F)F)C=C1 GIYXAJPCNFJEHY-UHFFFAOYSA-N 0.000 abstract 2
- 239000002253 acid Substances 0.000 abstract 1
- 230000001430 anti-depressive effect Effects 0.000 abstract 1
- 239000000935 antidepressant agent Substances 0.000 abstract 1
- 229940005513 antidepressants Drugs 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 239000012467 final product Substances 0.000 abstract 1
- 229960000389 fluoxetine hydrochloride Drugs 0.000 abstract 1
- 125000000250 methylamino group Chemical group [H]N(*)C([H])([H])[H] 0.000 abstract 1
- QULYNCCPRWKEMF-UHFFFAOYSA-N parachlorobenzotrifluoride Chemical compound FC(F)(F)C1=CC=C(Cl)C=C1 QULYNCCPRWKEMF-UHFFFAOYSA-N 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C217/00—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton
- C07C217/02—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton
- C07C217/48—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being unsaturated and containing rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C213/00—Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton
- C07C213/06—Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton from hydroxy amines by reactions involving the etherification or esterification of hydroxy groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Catalysts (AREA)
- Jib Cranes (AREA)
- Indexing, Searching, Synchronizing, And The Amount Of Synchronization Travel Of Record Carriers (AREA)
- Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FI891015A FI81083C (fi) | 1989-03-03 | 1989-03-03 | Ett foerbaettrat foerfarande foer framstaellning av n-metyl-3-(p-trifluormetylfenoxi)-3-fenylpropylamin hydroklorid. |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BG51156A3 true BG51156A3 (en) | 1993-02-15 |
Family
ID=8527991
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BG091247A BG51156A3 (en) | 1989-03-03 | 1990-02-20 | Process for the preparation of n-methyl-3/p-trifluoromrthylphenoxy/-3-phenyl-propylamine hydrochloride |
Country Status (24)
| Country | Link |
|---|---|
| EP (1) | EP0391070B1 (xx) |
| JP (1) | JPH0791244B2 (xx) |
| AT (1) | ATE100440T1 (xx) |
| AU (1) | AU620497B2 (xx) |
| BG (1) | BG51156A3 (xx) |
| CA (1) | CA2010410C (xx) |
| CS (1) | CS276782B6 (xx) |
| DD (1) | DD297806A5 (xx) |
| DE (1) | DE69006072T2 (xx) |
| DK (2) | DK172360B1 (xx) |
| ES (1) | ES2062131T3 (xx) |
| FI (1) | FI81083C (xx) |
| HR (1) | HRP921278B1 (xx) |
| HU (1) | HU204769B (xx) |
| IE (1) | IE63650B1 (xx) |
| IL (1) | IL92802A (xx) |
| NO (1) | NO172284C (xx) |
| PL (1) | PL163884B1 (xx) |
| PT (1) | PT93302A (xx) |
| RO (1) | RO105802B1 (xx) |
| RU (1) | RU1779244C (xx) |
| SI (1) | SI9010015B (xx) |
| YU (1) | YU48249B (xx) |
| ZA (1) | ZA90739B (xx) |
Families Citing this family (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IL99316A (en) * | 1991-08-27 | 1995-03-15 | Teva Pharma | Production of fluoxetine and new intermediates |
| HU9202128D0 (en) * | 1992-06-26 | 1992-10-28 | Richter Gedeon Vegyeszet | Method for producing n-methyl-(3-phenyl-3-(4-[trifluoro-methyl])-phenooxi-)-amine |
| US5618968A (en) * | 1993-02-05 | 1997-04-08 | Pliva Farmaceutska Kemijska, Prehrambena I Kozmeticka Industrija, Dionicko Drustvo | N-substituted derivatives of N-methyl-3-(p-trifluoromethylphenoxy)-3-phenylpropylamine and the procedure for their preparation |
| US5362886A (en) * | 1993-10-12 | 1994-11-08 | Eli Lilly And Company | Asymmetric synthesis |
| ES2101650B1 (es) * | 1995-06-29 | 1998-01-16 | Lilly Sa | Procedimiento de preparacion de n-metil-3-fenil-3-(p-trifluorometilfenoxi) propilamina. |
| ES2101654B1 (es) * | 1995-07-24 | 1998-01-16 | Lilly Sa | Procedimiento de preparacion de n-metil-3-fenil-3-(p-trifluorometilfe noxi) propilamina. |
| ES2101655B1 (es) * | 1995-07-28 | 1998-01-16 | Lilly Sa | Procedimiento de preparacion de n-metil-3-fenil-3-(p-trifluorometilfe noxi) propilamina. |
| ES2103680B1 (es) * | 1995-08-03 | 1998-04-01 | Lilly Sa | Procedimiento de preparacion de n-metil-3-fenil-3- (p-trifluorometilfenoxi)propilamina. |
| ES2103681B1 (es) * | 1995-09-19 | 1998-04-01 | Lilly Sa | Procedimiento de preparacion de n-metil-3-fenil - (p-trifluorometilfenoxi) propilamina. |
| ES2120368B1 (es) * | 1996-06-14 | 1999-07-01 | Almirall Prodesfarma Sa | Procedimiento de obtencion de n-metil-3-(p-trifluorometilfenoxi)-3-fenilpropilamina y sus sales farmaceuticamente aceptables. |
| TW514634B (en) * | 1997-10-14 | 2002-12-21 | Lilly Co Eli | Process to make chiral compounds |
| US6008412A (en) * | 1997-10-14 | 1999-12-28 | Eli Lilly And Company | Process to make chiral compounds |
| US6025517A (en) * | 1998-08-03 | 2000-02-15 | Sepracor Inc. | Fluoxetine process from benzoylacetonitrile |
| AU3877500A (en) * | 1999-04-09 | 2000-11-14 | Eli Lilly And Company | Methods for preparing 3-aryloxy-3-arylpropylamines and intermediates thereof |
| US6258853B1 (en) | 2001-01-31 | 2001-07-10 | Grayson Walker Stowell | Form a of fluoxetine hydrochloride |
| US6310251B1 (en) | 2001-01-31 | 2001-10-30 | Grayson Walker Stowell | Form a of fluoxetine hydrochloride |
| US6310250B1 (en) | 2001-01-31 | 2001-10-30 | Grayson Walker Stowell | Form A of fluoxetine hydrochloride |
| US6313350B1 (en) | 2001-01-31 | 2001-11-06 | Grayson Walker Stowell | Form a of fluoxetine hydrochloride |
| US6316672B1 (en) | 2001-01-31 | 2001-11-13 | Grayson Walker Stowell | Form a of fluoxetine hydrochloride |
| JP4769464B2 (ja) * | 2005-01-12 | 2011-09-07 | 広栄化学工業株式会社 | アルコール化合物の製造方法 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4314081A (en) * | 1974-01-10 | 1982-02-02 | Eli Lilly And Company | Arloxyphenylpropylamines |
| GB2060618A (en) * | 1979-09-14 | 1981-05-07 | Wyeth John & Brother Ltd | 3-Aryl-3-Aryloxypropylamines |
| JPS6172736A (ja) * | 1984-09-18 | 1986-04-14 | Toyo Soda Mfg Co Ltd | エフエドリン誘導体およびその製造方法 |
| GB8500482D0 (en) * | 1985-01-09 | 1985-02-13 | Shell Int Research | Substituted phenyl ethers |
-
1989
- 1989-03-03 FI FI891015A patent/FI81083C/fi not_active IP Right Cessation
- 1989-12-19 IL IL9280289A patent/IL92802A/en unknown
- 1989-12-20 IE IE411889A patent/IE63650B1/en not_active IP Right Cessation
-
1990
- 1990-01-04 SI SI9010015A patent/SI9010015B/sl unknown
- 1990-01-04 YU YU1590A patent/YU48249B/sh unknown
- 1990-01-31 ZA ZA90739A patent/ZA90739B/xx unknown
- 1990-02-20 CA CA002010410A patent/CA2010410C/en not_active Expired - Fee Related
- 1990-02-20 BG BG091247A patent/BG51156A3/xx unknown
- 1990-02-20 AU AU49969/90A patent/AU620497B2/en not_active Ceased
- 1990-02-26 DD DD90338155A patent/DD297806A5/de unknown
- 1990-02-26 DK DK049790A patent/DK172360B1/da not_active IP Right Cessation
- 1990-03-01 EP EP90104018A patent/EP0391070B1/en not_active Revoked
- 1990-03-01 CS CS901003A patent/CS276782B6/cs not_active IP Right Cessation
- 1990-03-01 ES ES90104018T patent/ES2062131T3/es not_active Expired - Lifetime
- 1990-03-01 DE DE69006072T patent/DE69006072T2/de not_active Revoked
- 1990-03-01 PT PT93302A patent/PT93302A/pt not_active Application Discontinuation
- 1990-03-01 DK DK90104018.8T patent/DK0391070T3/da active
- 1990-03-01 AT AT90104018T patent/ATE100440T1/de not_active IP Right Cessation
- 1990-03-02 RO RO144334A patent/RO105802B1/ro unknown
- 1990-03-02 NO NO901013A patent/NO172284C/no not_active IP Right Cessation
- 1990-03-02 HU HU901276A patent/HU204769B/hu not_active IP Right Cessation
- 1990-03-02 PL PL90284147A patent/PL163884B1/pl unknown
- 1990-03-02 JP JP2052564A patent/JPH0791244B2/ja not_active Expired - Fee Related
- 1990-03-02 RU SU904743358A patent/RU1779244C/ru active
-
1992
- 1992-11-16 HR HRP-15/90A patent/HRP921278B1/xx not_active IP Right Cessation
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