DK172360B1 - Fremgangsmåde til fremstilling af N-metyl-3-(p-trifluor-metylfenoxy)-3-fenylpropylamin og farmaceutisk acceptable syreadditionssalte deraf - Google Patents

Fremgangsmåde til fremstilling af N-metyl-3-(p-trifluor-metylfenoxy)-3-fenylpropylamin og farmaceutisk acceptable syreadditionssalte deraf Download PDF

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Publication number
DK172360B1
DK172360B1 DK049790A DK49790A DK172360B1 DK 172360 B1 DK172360 B1 DK 172360B1 DK 049790 A DK049790 A DK 049790A DK 49790 A DK49790 A DK 49790A DK 172360 B1 DK172360 B1 DK 172360B1
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DK
Denmark
Prior art keywords
methyl
formula
trifluoromethylphenoxy
phenylpropylamine
phenyl
Prior art date
Application number
DK049790A
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Danish (da)
English (en)
Other versions
DK49790A (da
DK49790D0 (da
Inventor
Pekka Juhani Kairisalo
Petri Juhani Hukka
Anitta Hannele Jaervinen
Original Assignee
Orion Yhtymae Oy
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Application filed by Orion Yhtymae Oy filed Critical Orion Yhtymae Oy
Publication of DK49790D0 publication Critical patent/DK49790D0/da
Publication of DK49790A publication Critical patent/DK49790A/da
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C217/00—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton
    • C07C217/02—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C217/48—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being unsaturated and containing rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C213/00—Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton
    • C07C213/06—Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton from hydroxy amines by reactions involving the etherification or esterification of hydroxy groups

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Catalysts (AREA)
  • Indexing, Searching, Synchronizing, And The Amount Of Synchronization Travel Of Record Carriers (AREA)
  • Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
  • Jib Cranes (AREA)
DK049790A 1989-03-03 1990-02-26 Fremgangsmåde til fremstilling af N-metyl-3-(p-trifluor-metylfenoxy)-3-fenylpropylamin og farmaceutisk acceptable syreadditionssalte deraf DK172360B1 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FI891015A FI81083C (fi) 1989-03-03 1989-03-03 Ett foerbaettrat foerfarande foer framstaellning av n-metyl-3-(p-trifluormetylfenoxi)-3-fenylpropylamin hydroklorid.
FI891015 1989-03-03

Publications (3)

Publication Number Publication Date
DK49790D0 DK49790D0 (da) 1990-02-26
DK49790A DK49790A (da) 1990-09-04
DK172360B1 true DK172360B1 (da) 1998-04-14

Family

ID=8527991

Family Applications (2)

Application Number Title Priority Date Filing Date
DK049790A DK172360B1 (da) 1989-03-03 1990-02-26 Fremgangsmåde til fremstilling af N-metyl-3-(p-trifluor-metylfenoxy)-3-fenylpropylamin og farmaceutisk acceptable syreadditionssalte deraf
DK90104018.8T DK0391070T3 (da) 1989-03-03 1990-03-01 Fremgangsmåde til fremstilling af N-methyl-3-(p-trifluormethylphenoxy)-3-phenylpropylaminer og deres salte

Family Applications After (1)

Application Number Title Priority Date Filing Date
DK90104018.8T DK0391070T3 (da) 1989-03-03 1990-03-01 Fremgangsmåde til fremstilling af N-methyl-3-(p-trifluormethylphenoxy)-3-phenylpropylaminer og deres salte

Country Status (24)

Country Link
EP (1) EP0391070B1 (sl)
JP (1) JPH0791244B2 (sl)
AT (1) ATE100440T1 (sl)
AU (1) AU620497B2 (sl)
BG (1) BG51156A3 (sl)
CA (1) CA2010410C (sl)
CS (1) CS276782B6 (sl)
DD (1) DD297806A5 (sl)
DE (1) DE69006072T2 (sl)
DK (2) DK172360B1 (sl)
ES (1) ES2062131T3 (sl)
FI (1) FI81083C (sl)
HR (1) HRP921278B1 (sl)
HU (1) HU204769B (sl)
IE (1) IE63650B1 (sl)
IL (1) IL92802A (sl)
NO (1) NO172284C (sl)
PL (1) PL163884B1 (sl)
PT (1) PT93302A (sl)
RO (1) RO105802B1 (sl)
RU (1) RU1779244C (sl)
SI (1) SI9010015B (sl)
YU (1) YU48249B (sl)
ZA (1) ZA90739B (sl)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL99316A (en) 1991-08-27 1995-03-15 Teva Pharma Production of fluoxetine and new intermediates
HU9202128D0 (en) * 1992-06-26 1992-10-28 Richter Gedeon Vegyeszet Method for producing n-methyl-(3-phenyl-3-(4-[trifluoro-methyl])-phenooxi-)-amine
US5618968A (en) * 1993-02-05 1997-04-08 Pliva Farmaceutska Kemijska, Prehrambena I Kozmeticka Industrija, Dionicko Drustvo N-substituted derivatives of N-methyl-3-(p-trifluoromethylphenoxy)-3-phenylpropylamine and the procedure for their preparation
US5362886A (en) * 1993-10-12 1994-11-08 Eli Lilly And Company Asymmetric synthesis
ES2101650B1 (es) * 1995-06-29 1998-01-16 Lilly Sa Procedimiento de preparacion de n-metil-3-fenil-3-(p-trifluorometilfenoxi) propilamina.
ES2101654B1 (es) * 1995-07-24 1998-01-16 Lilly Sa Procedimiento de preparacion de n-metil-3-fenil-3-(p-trifluorometilfe noxi) propilamina.
ES2101655B1 (es) * 1995-07-28 1998-01-16 Lilly Sa Procedimiento de preparacion de n-metil-3-fenil-3-(p-trifluorometilfe noxi) propilamina.
ES2103680B1 (es) * 1995-08-03 1998-04-01 Lilly Sa Procedimiento de preparacion de n-metil-3-fenil-3- (p-trifluorometilfenoxi)propilamina.
ES2103681B1 (es) * 1995-09-19 1998-04-01 Lilly Sa Procedimiento de preparacion de n-metil-3-fenil - (p-trifluorometilfenoxi) propilamina.
ES2120368B1 (es) * 1996-06-14 1999-07-01 Almirall Prodesfarma Sa Procedimiento de obtencion de n-metil-3-(p-trifluorometilfenoxi)-3-fenilpropilamina y sus sales farmaceuticamente aceptables.
US6008412A (en) * 1997-10-14 1999-12-28 Eli Lilly And Company Process to make chiral compounds
TW514634B (en) * 1997-10-14 2002-12-21 Lilly Co Eli Process to make chiral compounds
US6025517A (en) * 1998-08-03 2000-02-15 Sepracor Inc. Fluoxetine process from benzoylacetonitrile
US6541668B1 (en) * 1999-04-09 2003-04-01 Eli Lilly And Company Methods for preparing 3-arloxy-3-arylpropylamines and intermediates thereof
US6313350B1 (en) 2001-01-31 2001-11-06 Grayson Walker Stowell Form a of fluoxetine hydrochloride
US6310251B1 (en) 2001-01-31 2001-10-30 Grayson Walker Stowell Form a of fluoxetine hydrochloride
US6316672B1 (en) 2001-01-31 2001-11-13 Grayson Walker Stowell Form a of fluoxetine hydrochloride
US6258853B1 (en) 2001-01-31 2001-07-10 Grayson Walker Stowell Form a of fluoxetine hydrochloride
US6310250B1 (en) 2001-01-31 2001-10-30 Grayson Walker Stowell Form A of fluoxetine hydrochloride
JP4769464B2 (ja) * 2005-01-12 2011-09-07 広栄化学工業株式会社 アルコール化合物の製造方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4314081A (en) * 1974-01-10 1982-02-02 Eli Lilly And Company Arloxyphenylpropylamines
GB2060618A (en) * 1979-09-14 1981-05-07 Wyeth John & Brother Ltd 3-Aryl-3-Aryloxypropylamines
JPS6172736A (ja) * 1984-09-18 1986-04-14 Toyo Soda Mfg Co Ltd エフエドリン誘導体およびその製造方法
GB8500482D0 (en) * 1985-01-09 1985-02-13 Shell Int Research Substituted phenyl ethers

Also Published As

Publication number Publication date
SI9010015B (sl) 1999-06-30
NO901013L (no) 1990-09-04
IE63650B1 (en) 1995-05-31
IE894118L (en) 1990-09-03
DK49790A (da) 1990-09-04
CS9001003A2 (en) 1991-09-15
FI81083C (fi) 1990-09-10
AU4996990A (en) 1990-09-06
EP0391070A1 (en) 1990-10-10
HU901276D0 (en) 1990-05-28
HRP921278B1 (en) 2000-04-30
EP0391070B1 (en) 1994-01-19
CS276782B6 (en) 1992-08-12
DK49790D0 (da) 1990-02-26
NO172284C (no) 1993-06-30
BG51156A3 (en) 1993-02-15
DE69006072D1 (de) 1994-03-03
YU1590A (en) 1991-10-31
PL163884B1 (pl) 1994-05-31
FI81083B (fi) 1990-05-31
JPH02282352A (ja) 1990-11-19
AU620497B2 (en) 1992-02-20
DD297806A5 (de) 1992-01-23
ES2062131T3 (es) 1994-12-16
FI891015A0 (fi) 1989-03-03
HRP921278A2 (en) 1995-08-31
YU48249B (sh) 1997-09-30
RU1779244C (ru) 1992-11-30
RO105802B1 (ro) 1992-12-30
ZA90739B (en) 1990-11-28
IL92802A (en) 1994-01-25
CA2010410C (en) 1997-03-18
CA2010410A1 (en) 1990-09-03
PT93302A (pt) 1990-11-07
ATE100440T1 (de) 1994-02-15
NO901013D0 (no) 1990-03-02
HUT54619A (en) 1991-03-28
JPH0791244B2 (ja) 1995-10-04
HU204769B (en) 1992-02-28
SI9010015A (sl) 1998-06-30
NO172284B (no) 1993-03-22
DE69006072T2 (de) 1994-06-30
DK0391070T3 (da) 1994-02-28

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A0 Application filed
B1 Patent granted (law 1993)
PBP Patent lapsed

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