DD201679A5 - Verfahren zur isomerisierung von ergolinderivaten - Google Patents

Verfahren zur isomerisierung von ergolinderivaten Download PDF

Info

Publication number
DD201679A5
DD201679A5 DD81233439A DD23343981A DD201679A5 DD 201679 A5 DD201679 A5 DD 201679A5 DD 81233439 A DD81233439 A DD 81233439A DD 23343981 A DD23343981 A DD 23343981A DD 201679 A5 DD201679 A5 DD 201679A5
Authority
DD
German Democratic Republic
Prior art keywords
items
item
hydrogen
derivatives
ergoline
Prior art date
Application number
DD81233439A
Other languages
German (de)
English (en)
Inventor
Zdenek Brich
Herbert Muehle
Original Assignee
Sandoz Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sandoz Ag filed Critical Sandoz Ag
Publication of DD201679A5 publication Critical patent/DD201679A5/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D457/00Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid
    • C07D457/02Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid with hydrocarbon or substituted hydrocarbon radicals, attached in position 8
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D457/00Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid
    • C07D457/04Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 8
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D457/00Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid
    • C07D457/04Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 8
    • C07D457/06Lysergic acid amides
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D457/00Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid
    • C07D457/10Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid with hetero atoms directly attached in position 8
    • C07D457/12Nitrogen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
DD81233439A 1980-09-23 1981-09-21 Verfahren zur isomerisierung von ergolinderivaten DD201679A5 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH712280A CH644606A5 (de) 1980-09-23 1980-09-23 Verfahren zur isomerisierung von 9,10-dihydrolysergsaeurederivaten.

Publications (1)

Publication Number Publication Date
DD201679A5 true DD201679A5 (de) 1983-08-03

Family

ID=4320306

Family Applications (1)

Application Number Title Priority Date Filing Date
DD81233439A DD201679A5 (de) 1980-09-23 1981-09-21 Verfahren zur isomerisierung von ergolinderivaten

Country Status (27)

Country Link
US (1) US4515950A (pl)
EP (1) EP0048695B1 (pl)
JP (1) JPS5785385A (pl)
KR (1) KR870001508B1 (pl)
AT (1) ATE7916T1 (pl)
AU (1) AU547647B2 (pl)
CA (1) CA1178581A (pl)
CH (1) CH644606A5 (pl)
CS (1) CS228518B2 (pl)
DD (1) DD201679A5 (pl)
DE (1) DE3164195D1 (pl)
DK (1) DK418781A (pl)
ES (1) ES8301982A1 (pl)
FI (1) FI70018C (pl)
GR (1) GR75044B (pl)
HU (1) HU185317B (pl)
IE (1) IE51593B1 (pl)
IL (1) IL63902A (pl)
MA (1) MA19281A1 (pl)
NO (1) NO155967C (pl)
NZ (1) NZ198436A (pl)
PH (1) PH19436A (pl)
PL (1) PL134179B1 (pl)
PT (1) PT73713B (pl)
SU (1) SU1152521A3 (pl)
YU (1) YU42426B (pl)
ZA (1) ZA816617B (pl)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3309493A1 (de) * 1983-03-14 1984-09-20 Schering AG, 1000 Berlin und 4709 Bergkamen Neue ergolin-derivate, verfahren zu ihrer herstellung sowie verwendung als arzneimittel
NL193541C (nl) * 1984-01-12 2000-01-04 Novartis Ag 8 Alfa-acylaminoergolinen, werkwijzen voor de bereiding daarvan en preparaten die ze bevatten.
DE3533675A1 (de) * 1985-09-19 1987-03-26 Schering Ag Neue 12- und 13-brom-ergolinderivate
DE3533672A1 (de) * 1985-09-19 1987-03-26 Schering Ag Neue 12- und 13-substituierte ergolinderivate
DE3708028A1 (de) * 1987-03-10 1988-09-22 Schering Ag Verfahren zur herstellung von 2,3ss-dihydroergolinen, 2-substituierte 2,3ss-dihydroergoline und ihre verwendung als arzneimittel
CN107428745A (zh) 2015-01-20 2017-12-01 Xoc制药股份有限公司 麦角灵化合物及其用途
EP3247357A4 (en) 2015-01-20 2018-07-11 Xoc Pharmaceuticals, Inc Isoergoline compounds and uses thereof
BR112019025420A2 (pt) 2017-06-01 2020-06-16 Xoc Pharmaceuticals, Inc. Compostos policíclicos e usos destes

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3817988A (en) * 1971-11-16 1974-06-18 Res Inst Medicine Chem PROCESS FOR 11,12-ENOLISATION OF 9a-HALO-11-KETO-STEROIDS
CH585750A5 (en) * 1973-10-12 1977-03-15 Sandoz Ag Prepn. of (8)-methyl-dihydro-lysergic acid derivs. - from (7)-ergolene-(8)-carboxylates by methylation and redn.
GB1517971A (en) * 1974-07-19 1978-07-19 Sandoz Ltd 8alpha-substituted ergoline i derivatives
US3968111A (en) * 1974-12-06 1976-07-06 Eli Lilly And Company 8,8-Disubstituted-6-methylergolines and related compounds
DE2656344A1 (de) * 1975-12-23 1977-07-07 Sandoz Ag Ergolinderivate, ihre verwendung und herstellung
EP0021206B1 (de) * 1979-06-13 1983-06-22 Schering Aktiengesellschaft Neue (Ergolin-yl)-N', N'-diäthylharnstoff-Derivate, ihre Herstellung und sie enthaltende Arzneimittel
US4246265A (en) * 1979-10-01 1981-01-20 Eli Lilly And Company 6-n-Propyl-8α-methoxymethyl or methylmercaptomethylergolines and related compounds
DE3001752A1 (de) * 1980-01-16 1981-07-30 Schering Ag Berlin Und Bergkamen, 1000 Berlin Verfahren zur herstellung von 8(alpha)-substituierten 6-methylergolinen

Also Published As

Publication number Publication date
IL63902A (en) 1986-07-31
CH644606A5 (de) 1984-08-15
YU42426B (en) 1988-08-31
FI70018B (fi) 1986-01-31
ES505669A0 (es) 1982-12-16
DE3164195D1 (en) 1984-07-19
ATE7916T1 (de) 1984-06-15
KR870001508B1 (ko) 1987-08-20
PH19436A (en) 1986-04-15
GR75044B (pl) 1984-07-12
PL134179B1 (en) 1985-07-31
KR830007641A (ko) 1983-11-04
EP0048695B1 (de) 1984-06-13
IE51593B1 (en) 1987-01-21
MA19281A1 (fr) 1982-04-01
HU185317B (en) 1985-01-28
US4515950A (en) 1985-05-07
FI70018C (fi) 1986-09-12
DK418781A (da) 1982-03-24
PL233129A1 (pl) 1982-05-10
EP0048695A1 (de) 1982-03-31
PT73713B (en) 1983-05-11
ES8301982A1 (es) 1982-12-16
NO155967C (no) 1987-07-01
CA1178581A (en) 1984-11-27
FI812894L (fi) 1982-03-24
ZA816617B (en) 1983-04-27
NZ198436A (en) 1985-07-12
JPS5785385A (en) 1982-05-28
PT73713A (en) 1981-10-01
CS228518B2 (en) 1984-05-14
IE812201L (en) 1982-03-23
NO155967B (no) 1987-03-23
AU547647B2 (en) 1985-10-31
YU227581A (en) 1983-10-31
NO813196L (no) 1982-03-24
IL63902A0 (en) 1981-12-31
AU7555681A (en) 1982-04-01
SU1152521A3 (en) 1985-04-23

Similar Documents

Publication Publication Date Title
DE1261124B (de) Verfahren zur Herstellung von Pyrazolen
DE69104402T2 (de) Herstellungsverfahren für optisch aktive 3-Hydroxypyrrolidinderivate.
DD201679A5 (de) Verfahren zur isomerisierung von ergolinderivaten
DE1795841B2 (de) l-a'-Chlort-benzyl^-di-sec-butylamino-acetyl-pyiTol, seine Salze und Verfahren zu deren Herstellung
DE2447978C2 (de) Verfahren zur Herstellung einer Tropan-Verbindung
DE69013726T2 (de) Verbessertes Verfahren für die Herstellung von o-Carboxypyridyl- und o-Carboxychinolylimidazolinonen.
EP0854142B1 (de) Verfahren zur Herstellung von 1-Alkyl-pyrazol-5-carbonsäureestern
DE3811621A1 (de) Verfahren zur herstellung von 1h-imidazol-5-carbon-saeureestern oder -nitrilen und von pyrrol-3,4-carbonsaeureestern oder -nitrilen sowie verwendung der hergestellten verbindungen zur synthese von pilocarpin
DE2628469C3 (de) Verfahren zur Herstellung von γ -Aminoalkoholen
DE2525852C2 (pl)
EP0180890B1 (de) Verfahren zur diastereoselektiven Reduktion von 3-Amino-1-benzoxepin-5(2H)-onen
EP1104406B1 (de) Verfahren zur herstellung von 1-alkyl-pyrazol-5-carbonsäureestern iii
DE1022235C2 (de) Verfahren zur Foerderung der reduzierenden Wirkung von Metallalkoholaten auf reduzierbare, aromatische Stickstoffverbindungen
DE2331044A1 (de) Diphenylmethan-derivate und verfahren zu deren herstellung
DE1468624B2 (de) Verfahren zur herstellung von beta-cyanketonen
DE2536165A1 (de) Cyclopropylmethylamin-derivate
CH615422A5 (pl)
DE2508313C2 (de) Verfahren zur Herstellung von 17 beta-Hydroxy-4-androsten-3-onen
AT300785B (de) Verfahren zur Herstellung von neuen 1-Β-Phenylpropioloyl-3-indolylessigsäurederivaten
AT376417B (de) Verfahren zur herstellung von phenylaethanolaminen und ihren salzen
AT380874B (de) Verfahren zur herstellung von 1-(4-isopropylthiophenyl)-2-n.octyl-amino-propanol, dessen saeureadditionssalzen und estern
DE915938C (de) Verfahren zur Herstellung von Oxoacylaminen der Cyclopentanopolyhydrophenanthrenreihe
DD219767A5 (de) Verfahren zur herstellung von dihydroaryloxyalkylamino-1,2,4-triazol-derivaten
EP0542086A1 (de) Verfahren zur Herstellung von N-[(2-Chlor-pyridin-5-yl)methyl]-ethylendiamin
DE1643506B2 (de) N hoch 1 -Acylphenylhydrazine, ihre Salze Verfahren zu ihrer Herstellung und diese Verbindungen enthaltende Arzneimittel. Ausscheidung aus: 1620441

Legal Events

Date Code Title Description
ENJ Ceased due to non-payment of renewal fee