DK418781A - Fremgangsmaade til fremstilling af ergolinderivater - Google Patents
Fremgangsmaade til fremstilling af ergolinderivaterInfo
- Publication number
- DK418781A DK418781A DK418781A DK418781A DK418781A DK 418781 A DK418781 A DK 418781A DK 418781 A DK418781 A DK 418781A DK 418781 A DK418781 A DK 418781A DK 418781 A DK418781 A DK 418781A
- Authority
- DK
- Denmark
- Prior art keywords
- pct
- procedure
- preparation
- ergoline derivatives
- sec
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D457/00—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid
- C07D457/02—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid with hydrocarbon or substituted hydrocarbon radicals, attached in position 8
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D457/00—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid
- C07D457/04—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 8
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D457/00—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid
- C07D457/04—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 8
- C07D457/06—Lysergic acid amides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D457/00—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid
- C07D457/10—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid with hetero atoms directly attached in position 8
- C07D457/12—Nitrogen atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CH712280A CH644606A5 (de) | 1980-09-23 | 1980-09-23 | Verfahren zur isomerisierung von 9,10-dihydrolysergsaeurederivaten. |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK418781A true DK418781A (da) | 1982-03-24 |
Family
ID=4320306
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK418781A DK418781A (da) | 1980-09-23 | 1981-09-21 | Fremgangsmaade til fremstilling af ergolinderivater |
Country Status (27)
| Country | Link |
|---|---|
| US (1) | US4515950A (pl) |
| EP (1) | EP0048695B1 (pl) |
| JP (1) | JPS5785385A (pl) |
| KR (1) | KR870001508B1 (pl) |
| AT (1) | ATE7916T1 (pl) |
| AU (1) | AU547647B2 (pl) |
| CA (1) | CA1178581A (pl) |
| CH (1) | CH644606A5 (pl) |
| CS (1) | CS228518B2 (pl) |
| DD (1) | DD201679A5 (pl) |
| DE (1) | DE3164195D1 (pl) |
| DK (1) | DK418781A (pl) |
| ES (1) | ES505669A0 (pl) |
| FI (1) | FI70018C (pl) |
| GR (1) | GR75044B (pl) |
| HU (1) | HU185317B (pl) |
| IE (1) | IE51593B1 (pl) |
| IL (1) | IL63902A (pl) |
| MA (1) | MA19281A1 (pl) |
| NO (1) | NO155967C (pl) |
| NZ (1) | NZ198436A (pl) |
| PH (1) | PH19436A (pl) |
| PL (1) | PL134179B1 (pl) |
| PT (1) | PT73713B (pl) |
| SU (1) | SU1152521A3 (pl) |
| YU (1) | YU42426B (pl) |
| ZA (1) | ZA816617B (pl) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3309493A1 (de) * | 1983-03-14 | 1984-09-20 | Schering AG, 1000 Berlin und 4709 Bergkamen | Neue ergolin-derivate, verfahren zu ihrer herstellung sowie verwendung als arzneimittel |
| NL193541C (nl) * | 1984-01-12 | 2000-01-04 | Novartis Ag | 8 Alfa-acylaminoergolinen, werkwijzen voor de bereiding daarvan en preparaten die ze bevatten. |
| DE3533675A1 (de) * | 1985-09-19 | 1987-03-26 | Schering Ag | Neue 12- und 13-brom-ergolinderivate |
| DE3533672A1 (de) * | 1985-09-19 | 1987-03-26 | Schering Ag | Neue 12- und 13-substituierte ergolinderivate |
| DE3708028A1 (de) * | 1987-03-10 | 1988-09-22 | Schering Ag | Verfahren zur herstellung von 2,3ss-dihydroergolinen, 2-substituierte 2,3ss-dihydroergoline und ihre verwendung als arzneimittel |
| BR112017015487A2 (pt) | 2015-01-20 | 2018-01-30 | Xoc Pharmaceuticals Inc | Composto; composição; método de tratamento e/ou prevenção de enxaqueca, als, doença de alzheimer, doença de parkinson, distúrbios extrapirimidais, depressão, náusea, êmese, síndrome das pernas inquietas, insônia, agressão, doença de huntington, doença cardiopulmonar, fibrogênese, hipertensão arterial pulmonar, ansiedade, dependências a drogas, distonia, parassonia ou hiperlactinemia em um indivíduo; métodos de agonização dos receptores d2, 5-ht1d, 5-ht1a e 5-ht2c, em um indivíduo; método de antagonização do receptor d3 em um indivíduo; métodos de agonização seletiva dos receptores 5 -ht1d, e 5-ht2c, método de fornecimento de atividade de antagonista funcional no receptor 5 -ht2b ou no receptor 5-ht7, ou em ambos, em um indivíduo; método de fornecimento de atividade de antagonista funcional nos receptores adrenérgicos em um indivíduo |
| JP2018502889A (ja) | 2015-01-20 | 2018-02-01 | エックスオーシー ファーマシューティカルズ インコーポレイテッドＸｏｃ Ｐｈａｒｍａｃｅｕｔｉｃａｌｓ， Ｉｎｃ | イソエルゴリン化合物およびその使用 |
| WO2018223065A1 (en) | 2017-06-01 | 2018-12-06 | Xoc Pharmaceuticals, Inc. | Ergoline derivatives for use in medicine |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3817988A (en) * | 1971-11-16 | 1974-06-18 | Res Inst Medicine Chem | PROCESS FOR 11,12-ENOLISATION OF 9a-HALO-11-KETO-STEROIDS |
| CH585750A5 (en) * | 1973-10-12 | 1977-03-15 | Sandoz Ag | Prepn. of (8)-methyl-dihydro-lysergic acid derivs. - from (7)-ergolene-(8)-carboxylates by methylation and redn. |
| GB1517971A (en) * | 1974-07-19 | 1978-07-19 | Sandoz Ltd | 8alpha-substituted ergoline i derivatives |
| US3968111A (en) * | 1974-12-06 | 1976-07-06 | Eli Lilly And Company | 8,8-Disubstituted-6-methylergolines and related compounds |
| DE2656344A1 (de) * | 1975-12-23 | 1977-07-07 | Sandoz Ag | Ergolinderivate, ihre verwendung und herstellung |
| EP0021206B1 (de) * | 1979-06-13 | 1983-06-22 | Schering Aktiengesellschaft | Neue (Ergolin-yl)-N', N'-diäthylharnstoff-Derivate, ihre Herstellung und sie enthaltende Arzneimittel |
| US4246265A (en) * | 1979-10-01 | 1981-01-20 | Eli Lilly And Company | 6-n-Propyl-8α-methoxymethyl or methylmercaptomethylergolines and related compounds |
| DE3001752A1 (de) * | 1980-01-16 | 1981-07-30 | Schering Ag Berlin Und Bergkamen, 1000 Berlin | Verfahren zur herstellung von 8(alpha)-substituierten 6-methylergolinen |
-
1980
- 1980-09-23 CH CH712280A patent/CH644606A5/de not_active IP Right Cessation
-
1981
- 1981-09-16 FI FI812894A patent/FI70018C/fi not_active IP Right Cessation
- 1981-09-17 EP EP81810382A patent/EP0048695B1/de not_active Expired
- 1981-09-17 AT AT81810382T patent/ATE7916T1/de not_active IP Right Cessation
- 1981-09-17 DE DE8181810382T patent/DE3164195D1/de not_active Expired
- 1981-09-21 GR GR66104A patent/GR75044B/el unknown
- 1981-09-21 DD DD81233439A patent/DD201679A5/de not_active IP Right Cessation
- 1981-09-21 DK DK418781A patent/DK418781A/da not_active Application Discontinuation
- 1981-09-21 NO NO813196A patent/NO155967C/no unknown
- 1981-09-21 IL IL63902A patent/IL63902A/xx unknown
- 1981-09-21 PT PT73713A patent/PT73713B/pt unknown
- 1981-09-21 SU SU813338647A patent/SU1152521A3/ru active
- 1981-09-21 ES ES505669A patent/ES505669A0/es active Granted
- 1981-09-22 PH PH26242A patent/PH19436A/en unknown
- 1981-09-22 AU AU75556/81A patent/AU547647B2/en not_active Ceased
- 1981-09-22 MA MA19482A patent/MA19281A1/fr unknown
- 1981-09-22 HU HU812740A patent/HU185317B/hu not_active IP Right Cessation
- 1981-09-22 KR KR1019810003538A patent/KR870001508B1/ko not_active IP Right Cessation
- 1981-09-22 PL PL1981233129A patent/PL134179B1/pl unknown
- 1981-09-22 NZ NZ198436A patent/NZ198436A/en unknown
- 1981-09-22 CA CA000386357A patent/CA1178581A/en not_active Expired
- 1981-09-22 IE IE2201/81A patent/IE51593B1/en unknown
- 1981-09-22 YU YU2275/81A patent/YU42426B/xx unknown
- 1981-09-22 JP JP56150516A patent/JPS5785385A/ja active Pending
- 1981-09-23 CS CS817022A patent/CS228518B2/cs unknown
- 1981-09-23 US US06/375,290 patent/US4515950A/en not_active Expired - Fee Related
- 1981-09-23 ZA ZA816617A patent/ZA816617B/xx unknown
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| AHS | Application shelved for other reasons than non-payment |