FI812894L - Foerfarande foer isomerisering av ergolinderivat - Google Patents

Foerfarande foer isomerisering av ergolinderivat

Info

Publication number
FI812894L
FI812894L FI812894A FI812894A FI812894L FI 812894 L FI812894 L FI 812894L FI 812894 A FI812894 A FI 812894A FI 812894 A FI812894 A FI 812894A FI 812894 L FI812894 L FI 812894L
Authority
FI
Finland
Prior art keywords
isomerisering
ergolinderivat
pct
foerfarande foer
sec
Prior art date
Application number
FI812894A
Other languages
English (en)
Other versions
FI70018B (fi
FI70018C (fi
Inventor
Zdenek Brich
Herbert Muhle
Original Assignee
Sandoz Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sandoz Ag filed Critical Sandoz Ag
Publication of FI812894L publication Critical patent/FI812894L/fi
Publication of FI70018B publication Critical patent/FI70018B/fi
Application granted granted Critical
Publication of FI70018C publication Critical patent/FI70018C/fi

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D457/00—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid
    • C07D457/02—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid with hydrocarbon or substituted hydrocarbon radicals, attached in position 8
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D457/00—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid
    • C07D457/04—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 8
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D457/00—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid
    • C07D457/04—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 8
    • C07D457/06—Lysergic acid amides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D457/00—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid
    • C07D457/10—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid with hetero atoms directly attached in position 8
    • C07D457/12—Nitrogen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
FI812894A 1980-09-23 1981-09-16 Foerfarande foer isomerisering av ergolinderivat FI70018C (fi)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CH712280A CH644606A5 (de) 1980-09-23 1980-09-23 Verfahren zur isomerisierung von 9,10-dihydrolysergsaeurederivaten.
CH712280 1980-09-23

Publications (3)

Publication Number Publication Date
FI812894L true FI812894L (fi) 1982-03-24
FI70018B FI70018B (fi) 1986-01-31
FI70018C FI70018C (fi) 1986-09-12

Family

ID=4320306

Family Applications (1)

Application Number Title Priority Date Filing Date
FI812894A FI70018C (fi) 1980-09-23 1981-09-16 Foerfarande foer isomerisering av ergolinderivat

Country Status (27)

Country Link
US (1) US4515950A (fi)
EP (1) EP0048695B1 (fi)
JP (1) JPS5785385A (fi)
KR (1) KR870001508B1 (fi)
AT (1) ATE7916T1 (fi)
AU (1) AU547647B2 (fi)
CA (1) CA1178581A (fi)
CH (1) CH644606A5 (fi)
CS (1) CS228518B2 (fi)
DD (1) DD201679A5 (fi)
DE (1) DE3164195D1 (fi)
DK (1) DK418781A (fi)
ES (1) ES8301982A1 (fi)
FI (1) FI70018C (fi)
GR (1) GR75044B (fi)
HU (1) HU185317B (fi)
IE (1) IE51593B1 (fi)
IL (1) IL63902A (fi)
MA (1) MA19281A1 (fi)
NO (1) NO155967C (fi)
NZ (1) NZ198436A (fi)
PH (1) PH19436A (fi)
PL (1) PL134179B1 (fi)
PT (1) PT73713B (fi)
SU (1) SU1152521A3 (fi)
YU (1) YU42426B (fi)
ZA (1) ZA816617B (fi)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3309493A1 (de) * 1983-03-14 1984-09-20 Schering AG, 1000 Berlin und 4709 Bergkamen Neue ergolin-derivate, verfahren zu ihrer herstellung sowie verwendung als arzneimittel
HU197569B (en) * 1984-01-12 1989-04-28 Sandoz Ag Process for producing 8alpha-acylaminoergoline derivatives and pharmaceuticals comprising such compounds
DE3533675A1 (de) * 1985-09-19 1987-03-26 Schering Ag Neue 12- und 13-brom-ergolinderivate
DE3533672A1 (de) * 1985-09-19 1987-03-26 Schering Ag Neue 12- und 13-substituierte ergolinderivate
DE3708028A1 (de) * 1987-03-10 1988-09-22 Schering Ag Verfahren zur herstellung von 2,3ss-dihydroergolinen, 2-substituierte 2,3ss-dihydroergoline und ihre verwendung als arzneimittel
MX2017009406A (es) * 2015-01-20 2018-01-18 Xoc Pharmaceuticals Inc Compuestos de tipo isoergolina y usos de estos.
AU2016209492B2 (en) 2015-01-20 2020-10-22 Xoc Pharmaceuticals, Inc Ergoline compounds and uses thereof
AU2018275873A1 (en) 2017-06-01 2019-12-19 Xoc Pharmaceuticals, Inc. Ergoline derivatives for use in medicine

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3817988A (en) * 1971-11-16 1974-06-18 Res Inst Medicine Chem PROCESS FOR 11,12-ENOLISATION OF 9a-HALO-11-KETO-STEROIDS
CH585750A5 (en) * 1973-10-12 1977-03-15 Sandoz Ag Prepn. of (8)-methyl-dihydro-lysergic acid derivs. - from (7)-ergolene-(8)-carboxylates by methylation and redn.
GB1517973A (en) * 1974-07-19 1978-07-19 Sandoz Ltd 6-methyl-8alpha-n,n-dimethylsulphamoylaminoergoline i
US3968111A (en) * 1974-12-06 1976-07-06 Eli Lilly And Company 8,8-Disubstituted-6-methylergolines and related compounds
DE2656344A1 (de) * 1975-12-23 1977-07-07 Sandoz Ag Ergolinderivate, ihre verwendung und herstellung
EP0021206B1 (de) * 1979-06-13 1983-06-22 Schering Aktiengesellschaft Neue (Ergolin-yl)-N', N'-diäthylharnstoff-Derivate, ihre Herstellung und sie enthaltende Arzneimittel
US4246265A (en) * 1979-10-01 1981-01-20 Eli Lilly And Company 6-n-Propyl-8α-methoxymethyl or methylmercaptomethylergolines and related compounds
DE3001752A1 (de) * 1980-01-16 1981-07-30 Schering Ag Berlin Und Bergkamen, 1000 Berlin Verfahren zur herstellung von 8(alpha)-substituierten 6-methylergolinen

Also Published As

Publication number Publication date
US4515950A (en) 1985-05-07
CH644606A5 (de) 1984-08-15
JPS5785385A (en) 1982-05-28
EP0048695B1 (de) 1984-06-13
FI70018B (fi) 1986-01-31
AU7555681A (en) 1982-04-01
PT73713B (en) 1983-05-11
DK418781A (da) 1982-03-24
KR870001508B1 (ko) 1987-08-20
GR75044B (fi) 1984-07-12
ES505669A0 (es) 1982-12-16
CA1178581A (en) 1984-11-27
IE51593B1 (en) 1987-01-21
ATE7916T1 (de) 1984-06-15
IE812201L (en) 1982-03-23
IL63902A0 (en) 1981-12-31
NZ198436A (en) 1985-07-12
AU547647B2 (en) 1985-10-31
NO155967B (no) 1987-03-23
CS228518B2 (en) 1984-05-14
YU42426B (en) 1988-08-31
HU185317B (en) 1985-01-28
ES8301982A1 (es) 1982-12-16
PL134179B1 (en) 1985-07-31
MA19281A1 (fr) 1982-04-01
YU227581A (en) 1983-10-31
SU1152521A3 (en) 1985-04-23
EP0048695A1 (de) 1982-03-31
PT73713A (en) 1981-10-01
PH19436A (en) 1986-04-15
NO813196L (no) 1982-03-24
NO155967C (no) 1987-07-01
IL63902A (en) 1986-07-31
PL233129A1 (fi) 1982-05-10
ZA816617B (en) 1983-04-27
FI70018C (fi) 1986-09-12
KR830007641A (ko) 1983-11-04
DE3164195D1 (en) 1984-07-19
DD201679A5 (de) 1983-08-03

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Legal Events

Date Code Title Description
MM Patent lapsed

Owner name: SANDOZ AG