NO813196L - Fremgangsmaate for isomerisering av ergolinderivater. - Google Patents

Fremgangsmaate for isomerisering av ergolinderivater.

Info

Publication number
NO813196L
NO813196L NO813196A NO813196A NO813196L NO 813196 L NO813196 L NO 813196L NO 813196 A NO813196 A NO 813196A NO 813196 A NO813196 A NO 813196A NO 813196 L NO813196 L NO 813196L
Authority
NO
Norway
Prior art keywords
isomerization
pct
procedure
ergoline derivatives
sec
Prior art date
Application number
NO813196A
Other languages
English (en)
Other versions
NO155967B (no
NO155967C (no
Inventor
Zdenek Brich
Herbert Muehle
Original Assignee
Sandoz Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sandoz Ag filed Critical Sandoz Ag
Publication of NO813196L publication Critical patent/NO813196L/no
Publication of NO155967B publication Critical patent/NO155967B/no
Publication of NO155967C publication Critical patent/NO155967C/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D457/00—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid
    • C07D457/02—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid with hydrocarbon or substituted hydrocarbon radicals, attached in position 8
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D457/00—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid
    • C07D457/04—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 8
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D457/00—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid
    • C07D457/04—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 8
    • C07D457/06—Lysergic acid amides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D457/00—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid
    • C07D457/10—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid with hetero atoms directly attached in position 8
    • C07D457/12—Nitrogen atoms
NO813196A 1980-09-23 1981-09-21 Fremgangsmaate for fremstilling av ergolin ved isomerisering i 8-stillingen. NO155967C (no)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH712280A CH644606A5 (de) 1980-09-23 1980-09-23 Verfahren zur isomerisierung von 9,10-dihydrolysergsaeurederivaten.

Publications (3)

Publication Number Publication Date
NO813196L true NO813196L (no) 1982-03-24
NO155967B NO155967B (no) 1987-03-23
NO155967C NO155967C (no) 1987-07-01

Family

ID=4320306

Family Applications (1)

Application Number Title Priority Date Filing Date
NO813196A NO155967C (no) 1980-09-23 1981-09-21 Fremgangsmaate for fremstilling av ergolin ved isomerisering i 8-stillingen.

Country Status (27)

Country Link
US (1) US4515950A (no)
EP (1) EP0048695B1 (no)
JP (1) JPS5785385A (no)
KR (1) KR870001508B1 (no)
AT (1) ATE7916T1 (no)
AU (1) AU547647B2 (no)
CA (1) CA1178581A (no)
CH (1) CH644606A5 (no)
CS (1) CS228518B2 (no)
DD (1) DD201679A5 (no)
DE (1) DE3164195D1 (no)
DK (1) DK418781A (no)
ES (1) ES8301982A1 (no)
FI (1) FI70018C (no)
GR (1) GR75044B (no)
HU (1) HU185317B (no)
IE (1) IE51593B1 (no)
IL (1) IL63902A (no)
MA (1) MA19281A1 (no)
NO (1) NO155967C (no)
NZ (1) NZ198436A (no)
PH (1) PH19436A (no)
PL (1) PL134179B1 (no)
PT (1) PT73713B (no)
SU (1) SU1152521A3 (no)
YU (1) YU42426B (no)
ZA (1) ZA816617B (no)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3309493A1 (de) * 1983-03-14 1984-09-20 Schering AG, 1000 Berlin und 4709 Bergkamen Neue ergolin-derivate, verfahren zu ihrer herstellung sowie verwendung als arzneimittel
NL193541C (nl) * 1984-01-12 2000-01-04 Novartis Ag 8 Alfa-acylaminoergolinen, werkwijzen voor de bereiding daarvan en preparaten die ze bevatten.
DE3533672A1 (de) * 1985-09-19 1987-03-26 Schering Ag Neue 12- und 13-substituierte ergolinderivate
DE3533675A1 (de) * 1985-09-19 1987-03-26 Schering Ag Neue 12- und 13-brom-ergolinderivate
DE3708028A1 (de) * 1987-03-10 1988-09-22 Schering Ag Verfahren zur herstellung von 2,3ss-dihydroergolinen, 2-substituierte 2,3ss-dihydroergoline und ihre verwendung als arzneimittel
CA2974117A1 (en) 2015-01-20 2016-07-28 Xoc Pharmaceuticals, Inc. Ergoline compounds and uses thereof
MX2017009406A (es) * 2015-01-20 2018-01-18 Xoc Pharmaceuticals Inc Compuestos de tipo isoergolina y usos de estos.
EP3630758A1 (en) 2017-06-01 2020-04-08 Xoc Pharmaceuticals, Inc Ergoline derivatives for use in medicine

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3817988A (en) * 1971-11-16 1974-06-18 Res Inst Medicine Chem PROCESS FOR 11,12-ENOLISATION OF 9a-HALO-11-KETO-STEROIDS
CH585750A5 (en) * 1973-10-12 1977-03-15 Sandoz Ag Prepn. of (8)-methyl-dihydro-lysergic acid derivs. - from (7)-ergolene-(8)-carboxylates by methylation and redn.
GB1517971A (en) * 1974-07-19 1978-07-19 Sandoz Ltd 8alpha-substituted ergoline i derivatives
US3968111A (en) * 1974-12-06 1976-07-06 Eli Lilly And Company 8,8-Disubstituted-6-methylergolines and related compounds
DE2656344A1 (de) * 1975-12-23 1977-07-07 Sandoz Ag Ergolinderivate, ihre verwendung und herstellung
EP0021206B1 (de) * 1979-06-13 1983-06-22 Schering Aktiengesellschaft Neue (Ergolin-yl)-N', N'-diäthylharnstoff-Derivate, ihre Herstellung und sie enthaltende Arzneimittel
US4246265A (en) * 1979-10-01 1981-01-20 Eli Lilly And Company 6-n-Propyl-8α-methoxymethyl or methylmercaptomethylergolines and related compounds
DE3001752A1 (de) * 1980-01-16 1981-07-30 Schering Ag Berlin Und Bergkamen, 1000 Berlin Verfahren zur herstellung von 8(alpha)-substituierten 6-methylergolinen

Also Published As

Publication number Publication date
PL233129A1 (no) 1982-05-10
GR75044B (no) 1984-07-12
FI70018B (fi) 1986-01-31
DK418781A (da) 1982-03-24
CA1178581A (en) 1984-11-27
IL63902A (en) 1986-07-31
EP0048695A1 (de) 1982-03-31
FI70018C (fi) 1986-09-12
NZ198436A (en) 1985-07-12
ES505669A0 (es) 1982-12-16
PL134179B1 (en) 1985-07-31
IL63902A0 (en) 1981-12-31
NO155967B (no) 1987-03-23
PT73713B (en) 1983-05-11
ES8301982A1 (es) 1982-12-16
IE51593B1 (en) 1987-01-21
MA19281A1 (fr) 1982-04-01
AU7555681A (en) 1982-04-01
NO155967C (no) 1987-07-01
CH644606A5 (de) 1984-08-15
HU185317B (en) 1985-01-28
PH19436A (en) 1986-04-15
ATE7916T1 (de) 1984-06-15
KR870001508B1 (ko) 1987-08-20
JPS5785385A (en) 1982-05-28
YU227581A (en) 1983-10-31
FI812894L (fi) 1982-03-24
SU1152521A3 (en) 1985-04-23
EP0048695B1 (de) 1984-06-13
ZA816617B (en) 1983-04-27
IE812201L (en) 1982-03-23
KR830007641A (ko) 1983-11-04
US4515950A (en) 1985-05-07
AU547647B2 (en) 1985-10-31
YU42426B (en) 1988-08-31
DE3164195D1 (en) 1984-07-19
DD201679A5 (de) 1983-08-03
PT73713A (en) 1981-10-01
CS228518B2 (en) 1984-05-14

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