CZ289332B6 - Krystalická volná kyselina ceftiofuru, způsob její přípravy a farmaceutický prostředek s jejím obsahem - Google Patents
Krystalická volná kyselina ceftiofuru, způsob její přípravy a farmaceutický prostředek s jejím obsahem Download PDFInfo
- Publication number
- CZ289332B6 CZ289332B6 CZ19952290A CZ229095A CZ289332B6 CZ 289332 B6 CZ289332 B6 CZ 289332B6 CZ 19952290 A CZ19952290 A CZ 19952290A CZ 229095 A CZ229095 A CZ 229095A CZ 289332 B6 CZ289332 B6 CZ 289332B6
- Authority
- CZ
- Czechia
- Prior art keywords
- crystalline
- acid
- ceftiofur
- free acid
- oil
- Prior art date
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- QAZCPUUJMFBNJO-UHFFFAOYSA-N pyrrolidin-2-one;sodium Chemical compound [Na].O=C1CCCN1 QAZCPUUJMFBNJO-UHFFFAOYSA-N 0.000 description 1
- VMXUWOKSQNHOCA-LCYFTJDESA-N ranitidine Chemical compound [O-][N+](=O)/C=C(/NC)NCCSCC1=CC=C(CN(C)C)O1 VMXUWOKSQNHOCA-LCYFTJDESA-N 0.000 description 1
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Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
- A61K31/542—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame ortho- or peri-condensed with heterocyclic ring systems
- A61K31/545—Compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins, cefaclor, or cephalexine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Virology (AREA)
- Cephalosporin Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US3329193A | 1993-03-12 | 1993-03-12 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CZ9502290A3 CZ9502290A3 (cs) | 2001-08-15 |
| CZ289332B6 true CZ289332B6 (cs) | 2002-01-16 |
Family
ID=21869579
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CZ19952290A CZ289332B6 (cs) | 1993-03-12 | 1994-03-07 | Krystalická volná kyselina ceftiofuru, způsob její přípravy a farmaceutický prostředek s jejím obsahem |
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| US (1) | US5721359A (forum.php) |
| EP (1) | EP0690864B1 (forum.php) |
| JP (1) | JP3852946B2 (forum.php) |
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| AU (1) | AU694419B2 (forum.php) |
| BR (1) | BR1101034A (forum.php) |
| CA (1) | CA2155322C (forum.php) |
| CZ (1) | CZ289332B6 (forum.php) |
| DE (2) | DE122005000055I2 (forum.php) |
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| ES (1) | ES2157254T3 (forum.php) |
| FI (1) | FI120307B (forum.php) |
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| HU (1) | HU222244B1 (forum.php) |
| IL (1) | IL108910A (forum.php) |
| LU (1) | LU91206I2 (forum.php) |
| LV (1) | LV12889B (forum.php) |
| NL (1) | NL300208I2 (forum.php) |
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| SI (1) | SI0690864T1 (forum.php) |
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| TW (1) | TW267170B (forum.php) |
| WO (1) | WO1994020505A1 (forum.php) |
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Families Citing this family (73)
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| US5736151A (en) * | 1996-12-09 | 1998-04-07 | Pharmacia & Upjohn Company | Antibiotic oil suspensions |
| US6074657A (en) * | 1997-03-20 | 2000-06-13 | Pharmacia & Upjohn Company | Administration of an injectable antibiotic in the ear of an animal |
| MXPA03002055A (es) * | 2000-09-12 | 2004-12-13 | Upjohn Co | Composicion farmaceutica con excipiente modificado. |
| US7829100B2 (en) * | 2000-09-12 | 2010-11-09 | Teagarden Dirk L | Pharmaceutical composition having modified carrier |
| KR100423895B1 (ko) * | 2001-02-19 | 2004-03-24 | 주식회사 엘지생명과학 | 셉티오퍼 하이드로클로라이드의 현탁제 조성물 |
| CA2453182A1 (en) * | 2001-07-10 | 2003-01-23 | Meredith L. Greene | Crystalline thiazine oxazolidinones |
| JP4159988B2 (ja) * | 2001-08-15 | 2008-10-01 | ファルマシア・アンド・アップジョン・カンパニー・エルエルシー | Ｎ−［２−（ジエチルアミノ）エチル］−５−［（５−フルオロ−１，２−ジヒドロ−２−オキソ−３ｈ−インドール−３−イリデン）メチル］−２，４−ジメチル−１ｈ−ピロール−３−カルボキシアミドのリンゴ酸塩を含む結晶、その製法およびその組成物 |
| KR20040097187A (ko) | 2002-03-21 | 2004-11-17 | 파마시아 앤드 업존 캄파니 | 동물의 귀로의 주사가능한 항생제의 투여 방법 |
| US20040022815A1 (en) * | 2002-08-05 | 2004-02-05 | Orchid Health Care | Novel pharmaceutical composition of ceftiofur |
| KR20040015622A (ko) * | 2002-08-13 | 2004-02-19 | 대한뉴팜(주) | 세프티오푸르나트륨을 활성성분으로 함유하는 현탁주사액조성물 |
| US20040115822A1 (en) * | 2002-09-12 | 2004-06-17 | Schapaugh Randal Lee | Methods of measuring the dissolution rate of an analyte in a non-aqueous liquid composition |
| US7659061B2 (en) * | 2002-11-19 | 2010-02-09 | Pharmacia & Upjohn Company | Pharmaceutical compositions having a modified vehicle |
| US20040115837A1 (en) * | 2002-11-27 | 2004-06-17 | Schapaugh Randal Lee | Methods of measuring the dissolution rate of an analyte in a non-aqueous liquid composition |
| US7842791B2 (en) * | 2002-12-19 | 2010-11-30 | Nancy Jean Britten | Dispersible pharmaceutical compositions |
| SI1606293T1 (sl) * | 2003-03-27 | 2009-10-31 | Basilea Pharmaceutica Ag | Cefalosporin v kristalni obliki |
| KR101156406B1 (ko) | 2004-03-25 | 2012-06-13 | 아스텔라스세이야쿠 가부시키가이샤 | 솔리페나신 또는 그의 염의 고형 제제용 조성물 |
| US7815939B2 (en) | 2005-07-20 | 2010-10-19 | Astellas Pharma Inc. | Coated fine particles containing drug for intrabuccally fast disintegrating dosage forms |
| US8470809B2 (en) * | 2005-10-12 | 2013-06-25 | Orchid Chemicals & Pharmaceuticals Limited | Crystalline sodium salt of cephalosporin antibiotic |
| US8212024B2 (en) * | 2005-10-12 | 2012-07-03 | Orchid Chemicals & Pharmaceuticals Ltd. | Crystalline sodium salt of cephalosporin antibiotic |
| DK2195293T3 (da) | 2007-08-22 | 2014-02-03 | Astrazeneca Ab | Cyclopropylamidderivater |
| EP2303026B1 (en) | 2008-06-17 | 2020-09-09 | Brigham Young University | Cationic steroid antimicrobial diagnostic, detection, screening and imaging methods |
| WO2010020871A2 (en) * | 2008-08-22 | 2010-02-25 | Orchid Chemicals & Pharmaceuticals Limited | Crystalline sodium salt of cephalosporin antibiotic |
| JP5685193B2 (ja) * | 2008-11-19 | 2015-03-18 | メリアル リミテッド | セフチオフルおよびケトプロフェンとまたはセフチオフルとベンジルアルコールとを含む製剤 |
| CN102405047B (zh) * | 2009-01-30 | 2014-07-09 | 葛兰素史密斯克莱有限责任公司 | 结晶型的n-{(1s)-2-氨基-1-[(3-氟苯基)甲基]乙基}-5-氯-4-(4-氯-1-甲基-1h-吡唑-5-基)-2-噻吩甲酰胺盐酸盐 |
| TW201039825A (en) | 2009-02-20 | 2010-11-16 | Astrazeneca Ab | Cyclopropyl amide derivatives 983 |
| EP2536685B1 (en) * | 2010-02-18 | 2015-04-08 | AstraZeneca AB | Processes for making cyclopropyl amide derivatives and intermediates associated therewith |
| EP2536701A4 (en) * | 2010-02-18 | 2014-05-07 | Astrazeneca Ab | SOLID FORMS WITH A CYCLOPROPYLAMID DERIVATIVE |
| EP2705044A1 (en) * | 2011-05-02 | 2014-03-12 | Zoetis Llc | Novel cephalosporins useful as antibacterial agents |
| JP6272224B2 (ja) | 2011-07-20 | 2018-01-31 | ブリガム・ヤング・ユニバーシティＢｒｉｇｈａｍ Ｙｏｕｎｇ Ｕｎｉｖｅｒｓｉｔｙ | 疎水性セラゲニン化合物、及びそれを組み込む装置 |
| CA2852989C (en) | 2011-09-13 | 2021-06-29 | Brigham Young University | Compositions for treating bone diseases and broken bones |
| US9694019B2 (en) | 2011-09-13 | 2017-07-04 | Brigham Young University | Compositions and methods for treating bone diseases and broken bones |
| US9161942B2 (en) | 2011-09-13 | 2015-10-20 | Brigham Young University | Methods and products for increasing the rate of healing of tissue wounds |
| US9603859B2 (en) | 2011-09-13 | 2017-03-28 | Brigham Young University | Methods and products for increasing the rate of healing of tissue wounds |
| BR112014015144B1 (pt) | 2011-12-21 | 2018-03-27 | Brigham Young University | Composição aquosa para cuidado oral, uso de um composto esteroide catiônico e método não- terapêutico de redução de compostos voláteis de enxofre |
| CN102584855B (zh) * | 2012-02-16 | 2014-06-25 | 青岛科技大学 | 一种改进的头孢噻呋的制备方法 |
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| JP6310396B2 (ja) * | 2012-12-03 | 2018-04-11 | 株式会社カネカ | 還元型補酵素ｑ１０誘導体およびその製造方法 |
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| JP6518230B2 (ja) | 2013-03-15 | 2019-05-22 | ブリガム・ヤング・ユニバーシティＢｒｉｇｈａｍ Ｙｏｕｎｇ Ｕｎｉｖｅｒｓｉｔｙ | 炎症、自己免疫疾患、および疼痛を治療する方法 |
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