ATE202109T1 - Kristallines ceftiofur (freie säure) - Google Patents

Kristallines ceftiofur (freie säure)

Info

Publication number
ATE202109T1
ATE202109T1 AT94910721T AT94910721T ATE202109T1 AT E202109 T1 ATE202109 T1 AT E202109T1 AT 94910721 T AT94910721 T AT 94910721T AT 94910721 T AT94910721 T AT 94910721T AT E202109 T1 ATE202109 T1 AT E202109T1
Authority
AT
Austria
Prior art keywords
pct
free acid
crystalline ceftiofur
date sep
ceftiofur
Prior art date
Application number
AT94910721T
Other languages
German (de)
English (en)
Inventor
Michael J Dunn
Michael S Bergren
Gregory E Hardee
Kenneth Paul Shephard
Robert S Chao
Jeffrey L Havens
Original Assignee
Upjohn Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Upjohn Co filed Critical Upjohn Co
Application granted granted Critical
Publication of ATE202109T1 publication Critical patent/ATE202109T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D501/00Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/54Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
    • A61K31/542Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/545Compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins, cefaclor, or cephalexine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Virology (AREA)
  • Cephalosporin Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
AT94910721T 1993-03-12 1994-03-07 Kristallines ceftiofur (freie säure) ATE202109T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US3329193A 1993-03-12 1993-03-12
PCT/US1994/001862 WO1994020505A1 (en) 1993-03-12 1994-03-07 Crystalline ceftiofur free acid

Publications (1)

Publication Number Publication Date
ATE202109T1 true ATE202109T1 (de) 2001-06-15

Family

ID=21869579

Family Applications (1)

Application Number Title Priority Date Filing Date
AT94910721T ATE202109T1 (de) 1993-03-12 1994-03-07 Kristallines ceftiofur (freie säure)

Country Status (31)

Country Link
US (1) US5721359A (forum.php)
EP (1) EP0690864B1 (forum.php)
JP (1) JP3852946B2 (forum.php)
KR (1) KR100296810B1 (forum.php)
CN (1) CN1055090C (forum.php)
AT (1) ATE202109T1 (forum.php)
AU (1) AU694419B2 (forum.php)
BR (1) BR1101034A (forum.php)
CA (1) CA2155322C (forum.php)
CZ (1) CZ289332B6 (forum.php)
DE (2) DE122005000055I2 (forum.php)
DK (1) DK0690864T3 (forum.php)
ES (1) ES2157254T3 (forum.php)
FI (1) FI120307B (forum.php)
FR (1) FR05C0045I2 (forum.php)
GR (1) GR3036514T3 (forum.php)
HU (1) HU222244B1 (forum.php)
IL (1) IL108910A (forum.php)
LU (1) LU91206I2 (forum.php)
LV (1) LV12889B (forum.php)
NL (1) NL300208I2 (forum.php)
NO (2) NO313199B1 (forum.php)
NZ (1) NZ263002A (forum.php)
PL (1) PL184611B1 (forum.php)
PT (1) PT690864E (forum.php)
RU (1) RU2136685C1 (forum.php)
SI (1) SI0690864T1 (forum.php)
SK (1) SK283674B6 (forum.php)
TW (1) TW267170B (forum.php)
WO (1) WO1994020505A1 (forum.php)
ZA (1) ZA941586B (forum.php)

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JP4159988B2 (ja) * 2001-08-15 2008-10-01 ファルマシア・アンド・アップジョン・カンパニー・エルエルシー N−[2−(ジエチルアミノ)エチル]−5−[(5−フルオロ−1,2−ジヒドロ−2−オキソ−3h−インドール−3−イリデン)メチル]−2,4−ジメチル−1h−ピロール−3−カルボキシアミドのリンゴ酸塩を含む結晶、その製法およびその組成物
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JP5685193B2 (ja) * 2008-11-19 2015-03-18 メリアル リミテッド セフチオフルおよびケトプロフェンとまたはセフチオフルとベンジルアルコールとを含む製剤
CN102405047B (zh) * 2009-01-30 2014-07-09 葛兰素史密斯克莱有限责任公司 结晶型的n-{(1s)-2-氨基-1-[(3-氟苯基)甲基]乙基}-5-氯-4-(4-氯-1-甲基-1h-吡唑-5-基)-2-噻吩甲酰胺盐酸盐
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CN102584855B (zh) * 2012-02-16 2014-06-25 青岛科技大学 一种改进的头孢噻呋的制备方法
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JP6518230B2 (ja) 2013-03-15 2019-05-22 ブリガム・ヤング・ユニバーシティBrigham Young University 炎症、自己免疫疾患、および疼痛を治療する方法
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RU2546675C2 (ru) * 2013-04-11 2015-04-10 Федеральное казённое предприятие "Государственный научно-исследовательский институт химических продуктов" (ФКП "ГосНИИХП") Способ определения степени кристалличности составов на основе дифениламина
US9387215B2 (en) 2013-04-22 2016-07-12 Brigham Young University Animal feed including cationic cholesterol additive and related methods
EP3360858B1 (en) * 2013-09-05 2020-04-29 Mitsubishi Tanabe Pharma Corporation Process for producing an aminopyrrolidine derivative
US11690855B2 (en) 2013-10-17 2023-07-04 Brigham Young University Methods for treating lung infections and inflammation
US20150203527A1 (en) 2014-01-23 2015-07-23 Brigham Young University Cationic steroidal antimicrobials
CA2844321C (en) 2014-02-27 2021-03-16 Brigham Young University Cationic steroidal antimicrobial compounds
US10220045B2 (en) 2014-03-13 2019-03-05 Brigham Young University Compositions and methods for forming stabilized compositions with reduced CSA agglomeration
US9867836B2 (en) 2014-03-13 2018-01-16 Brigham Young University Lavage and/or infusion using CSA compounds for increasing fertility in a mammal
US9931350B2 (en) 2014-03-14 2018-04-03 Brigham Young University Anti-infective and osteogenic compositions and methods of use
US9686966B2 (en) 2014-04-30 2017-06-27 Brigham Young University Methods and apparatus for cleaning or disinfecting a water delivery system
US10441595B2 (en) 2014-06-26 2019-10-15 Brigham Young University Methods for treating fungal infections
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Also Published As

Publication number Publication date
CZ289332B6 (cs) 2002-01-16
ES2157254T3 (es) 2001-08-16
HU222244B1 (hu) 2003-05-28
LV12889B (lv) 2002-12-20
DE69427469D1 (en) 2001-07-19
AU694419B2 (en) 1998-07-23
NZ263002A (en) 1996-12-20
DK0690864T3 (da) 2001-09-17
CA2155322C (en) 2000-02-29
DE122005000055I2 (de) 2008-06-05
HUT73781A (en) 1996-09-30
WO1994020505A1 (en) 1994-09-15
AU6351094A (en) 1994-09-26
JPH08507519A (ja) 1996-08-13
FR05C0045I1 (forum.php) 2006-01-06
NL300208I1 (nl) 2006-02-01
IL108910A0 (en) 1994-06-24
NO2005025I2 (no) 2010-11-22
US5721359A (en) 1998-02-24
CN1119016A (zh) 1996-03-20
SI0690864T1 (en) 2001-10-31
SK283674B6 (sk) 2003-11-04
NO953564D0 (no) 1995-09-11
FI954250A0 (fi) 1995-09-11
HU9501960D0 (en) 1995-09-28
CN1055090C (zh) 2000-08-02
DE69427469T2 (de) 2001-10-31
IL108910A (en) 1999-10-28
ZA941586B (en) 1995-09-07
JP3852946B2 (ja) 2006-12-06
PL184611B1 (pl) 2002-11-29
NO313199B1 (no) 2002-08-26
SK111495A3 (en) 1995-12-06
NO2005025I1 (no) 2005-12-05
EP0690864A1 (en) 1996-01-10
NL300208I2 (nl) 2006-05-01
KR100296810B1 (ko) 2001-10-24
GR3036514T3 (en) 2001-12-31
PL310556A1 (en) 1995-12-27
DE122005000055I1 (de) 2006-02-23
PT690864E (pt) 2001-11-30
LU91206I2 (fr) 2006-05-30
FI954250L (fi) 1995-09-11
FI120307B (fi) 2009-09-15
TW267170B (forum.php) 1996-01-01
BR1101034A (pt) 2002-04-30
FR05C0045I2 (forum.php) 2007-08-03
CA2155322A1 (en) 1994-09-15
NO953564L (no) 1995-11-07
RU2136685C1 (ru) 1999-09-10
EP0690864B1 (en) 2001-06-13
CZ9502290A3 (cs) 2001-08-15

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