|
US3361742A
(en)
|
1964-12-07 |
1968-01-02 |
Hoffmann La Roche |
5-oxo-1h-pyrrolo-[2, 1-c][1, 4]-benzodiazepin-2-crylamides
|
|
US3523941A
(en)
|
1967-03-06 |
1970-08-11 |
Hoffmann La Roche |
Benzodiazepine compounds and process for their preparation
|
|
US3524849A
(en)
|
1967-10-27 |
1970-08-18 |
Hoffmann La Roche |
Process for the preparation of pyrrolo-benzodiazepine acrylamides and intermediates useful therein
|
|
DE1965304A1
(de)
|
1968-12-30 |
1970-07-23 |
Fujisawa Pharmaceutical Co |
Benzdiazepinon-Verbindungen und Verfahren zu ihrer Herstellung
|
|
IL33558A
(en)
|
1968-12-30 |
1973-10-25 |
Fujisawa Pharmaceutical Co |
Antibiotic pyrrolo-benzodiazepine compound,its derivatives and processes for their production
|
|
JPS4843755B1
(enExample)
|
1969-06-26 |
1973-12-20 |
|
|
|
JPS6053033B2
(ja)
|
1976-12-28 |
1985-11-22 |
財団法人微生物化学研究会 |
新制癌抗生物質マゼスラマイシン及びその製造方法
|
|
JPS585916B2
(ja)
|
1977-12-27 |
1983-02-02 |
株式会社ミドリ十字 |
新規ベンゾジアゼピン系化合物
|
|
JPS5615289A
(en)
|
1979-07-17 |
1981-02-14 |
Green Cross Corp:The |
Novel benzodiazepinnbased compound 3
|
|
JPS57131791A
(en)
|
1980-12-31 |
1982-08-14 |
Fujisawa Pharmaceut Co Ltd |
Benzodiazepine derivative and its preparation
|
|
CA1185602A
(en)
|
1981-02-27 |
1985-04-16 |
Emilio Kyburz |
Imidazodiazepines
|
|
CA1184175A
(en)
|
1981-02-27 |
1985-03-19 |
Walter Hunkeler |
Imidazodiazepines
|
|
CA1173441A
(en)
|
1981-02-27 |
1984-08-28 |
Hoffmann-La Roche Limited |
Imidazodiazepines
|
|
JPS58180487A
(ja)
|
1982-04-16 |
1983-10-21 |
Kyowa Hakko Kogyo Co Ltd |
抗生物質dc−81およびその製造法
|
|
US4427588A
(en)
|
1982-11-08 |
1984-01-24 |
Bristol-Myers Company |
Process for conversion of oxotomaymycin to tomaymycin
|
|
US4427587A
(en)
|
1982-11-10 |
1984-01-24 |
Bristol-Myers Company |
Total synthesis of antitumor antibiotics BBM-2040A and BBM-2040B
|
|
JPS59152329A
(ja)
|
1983-02-17 |
1984-08-31 |
Green Cross Corp:The |
局所障害抑制剤
|
|
US4816567A
(en)
|
1983-04-08 |
1989-03-28 |
Genentech, Inc. |
Recombinant immunoglobin preparations
|
|
FR2586683B1
(fr)
|
1985-08-29 |
1988-07-01 |
Centre Nat Rech Scient |
Nouveaux derives de neothramycine, leur procede de preparation et leur application en tant que medicaments
|
|
US5583024A
(en)
|
1985-12-02 |
1996-12-10 |
The Regents Of The University Of California |
Recombinant expression of Coleoptera luciferase
|
|
JP2660201B2
(ja)
|
1988-08-05 |
1997-10-08 |
塩野義製薬株式会社 |
新規ピロロ[1,4]ベンゾジアゼピン誘導体および老人性痴呆薬
|
|
CA2023779A1
(en)
|
1989-08-23 |
1991-02-24 |
Margaret D. Moore |
Compositions and methods for detection and treatment of epstein-barr virus infection and immune disorders
|
|
JPH053790A
(ja)
|
1990-04-19 |
1993-01-14 |
Fujisawa Pharmaceut Co Ltd |
デヒドロペプチダーゼ−i
|
|
US5256643A
(en)
|
1990-05-29 |
1993-10-26 |
The Government Of The United States |
Human cripto protein
|
|
AU9016591A
(en)
|
1990-10-25 |
1992-05-26 |
Tanox Biosystems, Inc. |
Glycoproteins associated with membrane-bound immunoglobulins as antibody targets on B cells
|
|
DE69231223T3
(de)
|
1991-03-29 |
2008-01-17 |
Genentech, Inc., South San Francisco |
Menschliche pf4a rezeptoren und ihre verwendung
|
|
US5440021A
(en)
|
1991-03-29 |
1995-08-08 |
Chuntharapai; Anan |
Antibodies to human IL-8 type B receptor
|
|
US5543503A
(en)
|
1991-03-29 |
1996-08-06 |
Genentech Inc. |
Antibodies to human IL-8 type A receptor
|
|
FR2676230B1
(fr)
|
1991-05-07 |
1993-08-27 |
Centre Nat Rech Scient |
Nouveaux derives de pyrrolo [1,4]-benzodiazepines, leur procede de preparation et medicaments les contenant.
|
|
JP3050424B2
(ja)
|
1991-07-12 |
2000-06-12 |
塩野義製薬株式会社 |
ヒトエンドセリンリセプター
|
|
US5264557A
(en)
|
1991-08-23 |
1993-11-23 |
The United States Of America As Represented By The Department Of Health And Human Services |
Polypeptide of a human cripto-related gene, CR-3
|
|
US5362852A
(en)
|
1991-09-27 |
1994-11-08 |
Pfizer Inc. |
Modified peptide derivatives conjugated at 2-hydroxyethylamine moieties
|
|
US6153408A
(en)
|
1991-11-15 |
2000-11-28 |
Institut Pasteur And Institut National De La Sante Et De La Recherche Medicale |
Altered major histocompatibility complex (MHC) determinant and methods of using the determinant
|
|
US6011146A
(en)
|
1991-11-15 |
2000-01-04 |
Institut Pasteur |
Altered major histocompatibility complex (MHC) determinant and methods of using the determinant
|
|
GB9205051D0
(en)
|
1992-03-09 |
1992-04-22 |
Cancer Res Campaign Tech |
Pyrrolobenzodiazepine derivatives,their preparation,and compositions containing them
|
|
FR2696176B1
(fr)
|
1992-09-28 |
1994-11-10 |
Synthelabo |
Dérivés de pipéridine, leur préparation et leur application en thérapeutique.
|
|
IL107366A
(en)
|
1992-10-23 |
2003-03-12 |
Chugai Pharmaceutical Co Ltd |
Genes coding for megakaryocyte potentiator
|
|
US5644033A
(en)
|
1992-12-22 |
1997-07-01 |
Health Research, Inc. |
Monoclonal antibodies that define a unique antigen of human B cell antigen receptor complex and methods of using same for diagnosis and treatment
|
|
US5801005A
(en)
|
1993-03-17 |
1998-09-01 |
University Of Washington |
Immune reactivity to HER-2/neu protein for diagnosis of malignancies in which the HER-2/neu oncogene is associated
|
|
US5869445A
(en)
|
1993-03-17 |
1999-02-09 |
University Of Washington |
Methods for eliciting or enhancing reactivity to HER-2/neu protein
|
|
US6214345B1
(en)
|
1993-05-14 |
2001-04-10 |
Bristol-Myers Squibb Co. |
Lysosomal enzyme-cleavable antitumor drug conjugates
|
|
GB9316162D0
(en)
|
1993-08-04 |
1993-09-22 |
Zeneca Ltd |
Fungicides
|
|
US5773223A
(en)
|
1993-09-02 |
1998-06-30 |
Chiron Corporation |
Endothelin B1, (ETB1) receptor polypeptide and its encoding nucleic acid methods, and uses thereof
|
|
EP0647450A1
(en)
|
1993-09-09 |
1995-04-12 |
BEHRINGWERKE Aktiengesellschaft |
Improved prodrugs for enzyme mediated activation
|
|
US5750370A
(en)
|
1995-06-06 |
1998-05-12 |
Human Genome Sciences, Inc. |
Nucleic acid encoding human endothlein-bombesin receptor and method of producing the receptor
|
|
JPH08336393A
(ja)
|
1995-04-13 |
1996-12-24 |
Mitsubishi Chem Corp |
光学活性なγ−置換−β−ヒドロキシ酪酸エステルの製造法
|
|
US5707829A
(en)
|
1995-08-11 |
1998-01-13 |
Genetics Institute, Inc. |
DNA sequences and secreted proteins encoded thereby
|
|
US20020193567A1
(en)
|
1995-08-11 |
2002-12-19 |
Genetics Institute, Inc. |
Secreted proteins and polynucleotides encoding them
|
|
JP3646191B2
(ja)
|
1996-03-19 |
2005-05-11 |
大塚製薬株式会社 |
ヒト遺伝子
|
|
US6218519B1
(en)
|
1996-04-12 |
2001-04-17 |
Pro-Neuron, Inc. |
Compounds and methods for the selective treatment of cancer and bacterial infections
|
|
AU722499B2
(en)
|
1996-05-17 |
2000-08-03 |
Schering Corporation |
Human B-cell antigens, related reagents
|
|
AU739028B2
(en)
|
1996-09-27 |
2001-10-04 |
Bristol-Myers Squibb Company |
Hydrolyzable prodrugs for delivery of anticancer drugs to metastatic cells
|
|
US6759509B1
(en)
|
1996-11-05 |
2004-07-06 |
Bristol-Myers Squibb Company |
Branched peptide linkers
|
|
US5945511A
(en)
|
1997-02-20 |
1999-08-31 |
Zymogenetics, Inc. |
Class II cytokine receptor
|
|
US20030185830A1
(en)
|
1997-02-25 |
2003-10-02 |
Corixa Corporation |
Compositions and methods for the therapy and diagnosis of prostate cancer
|
|
US7033827B2
(en)
|
1997-02-25 |
2006-04-25 |
Corixa Corporation |
Prostate-specific polynucleotide compositions
|
|
WO1998040403A1
(en)
|
1997-03-10 |
1998-09-17 |
The Regents Of The University Of California |
Psca: prostate stem cell antigen
|
|
US6261791B1
(en)
|
1997-03-10 |
2001-07-17 |
The Regents Of The University Of California |
Method for diagnosing cancer using specific PSCA antibodies
|
|
US6541212B2
(en)
|
1997-03-10 |
2003-04-01 |
The Regents Of The University Of California |
Methods for detecting prostate stem cell antigen protein
|
|
US6555339B1
(en)
|
1997-04-14 |
2003-04-29 |
Arena Pharmaceuticals, Inc. |
Non-endogenous, constitutively activated human protein-coupled receptors
|
|
US6319688B1
(en)
|
1997-04-28 |
2001-11-20 |
Smithkline Beecham Corporation |
Polynucleotide encoding human sodium dependent phosphate transporter (IPT-1)
|
|
WO1998051805A1
(en)
|
1997-05-15 |
1998-11-19 |
Abbott Laboratories |
Reagents and methods useful for detecting diseases of the prostate
|
|
WO1998051824A1
(en)
|
1997-05-15 |
1998-11-19 |
Abbott Laboratories |
Reagents and methods useful for detecting disease of the urinary tract
|
|
US6602677B1
(en)
|
1997-09-19 |
2003-08-05 |
Promega Corporation |
Thermostable luciferases and methods of production
|
|
US20030060612A1
(en)
|
1997-10-28 |
2003-03-27 |
Genentech, Inc. |
Compositions and methods for the diagnosis and treatment of tumor
|
|
US20020034749A1
(en)
|
1997-11-18 |
2002-03-21 |
Billing-Medel Patricia A. |
Reagents and methods useful for detecting diseases of the breast
|
|
US6110695A
(en)
|
1997-12-02 |
2000-08-29 |
The Regents Of The University Of California |
Modulating the interaction of the chemokine, B Lymphocyte Hemoattractant, and its Receptor, BLR1
|
|
DE69939527D1
(de)
|
1998-03-13 |
2008-10-23 |
Burnham Inst |
Zielsuchende verbindungen für verschiedene organe und gewebe
|
|
EP1078092B1
(en)
|
1998-05-13 |
2011-08-03 |
Epimmune Inc. |
Expression vectors for stimulating an immune response and methods of using the same
|
|
EP1080732A4
(en)
|
1998-05-22 |
2004-08-25 |
Daiichi Seiyaku Co |
DRUG COMPOSITION
|
|
US20030064397A1
(en)
|
1998-05-22 |
2003-04-03 |
Incyte Genomics, Inc. |
Transmembrane protein differentially expressed in prostate and lung tumors
|
|
US20020187472A1
(en)
|
2001-03-09 |
2002-12-12 |
Preeti Lal |
Steap-related protein
|
|
US20020113770A1
(en)
|
1998-07-08 |
2002-08-22 |
Joseph M. Jacobson |
Methods for achieving improved color in microencapsulated electrophoretic devices
|
|
DK1193270T3
(da)
|
1998-08-27 |
2003-09-15 |
Spirogen Ltd |
Pyrrolobenzodiazepiner
|
|
GB9818732D0
(en)
|
1998-08-27 |
1998-10-21 |
Univ Portsmouth |
Collection of compounds
|
|
GB9818730D0
(en)
|
1998-08-27 |
1998-10-21 |
Univ Portsmouth |
Collections of compounds
|
|
GB9818731D0
(en)
|
1998-08-27 |
1998-10-21 |
Univ Portsmouth |
Compounds
|
|
WO2000012130A1
(en)
|
1998-08-27 |
2000-03-09 |
Smithkline Beecham Corporation |
Rp105 agonists and antagonists
|
|
JP4689781B2
(ja)
|
1998-09-03 |
2011-05-25 |
独立行政法人科学技術振興機構 |
アミノ酸輸送蛋白及びその遺伝子
|
|
WO2000020579A1
(en)
|
1998-10-02 |
2000-04-13 |
Mcmaster University |
Spliced form of erbb-2/neu oncogene
|
|
WO2001057188A2
(en)
|
2000-02-03 |
2001-08-09 |
Hyseq, Inc. |
Novel nucleic acids and polypeptides
|
|
US20020119158A1
(en)
|
1998-12-17 |
2002-08-29 |
Corixa Corporation |
Compositions and methods for the therapy and diagnosis of ovarian cancer
|
|
US6858710B2
(en)
|
1998-12-17 |
2005-02-22 |
Corixa Corporation |
Compositions and methods for the therapy and diagnosis of ovarian cancer
|
|
US20030091580A1
(en)
|
2001-06-18 |
2003-05-15 |
Mitcham Jennifer L. |
Compositions and methods for the therapy and diagnosis of ovarian cancer
|
|
US6962980B2
(en)
|
1999-09-24 |
2005-11-08 |
Corixa Corporation |
Compositions and methods for the therapy and diagnosis of ovarian cancer
|
|
US6468546B1
(en)
|
1998-12-17 |
2002-10-22 |
Corixa Corporation |
Compositions and methods for therapy and diagnosis of ovarian cancer
|
|
DE69939553D1
(de)
|
1998-12-30 |
2008-10-23 |
Beth Israel Hospital |
Charakterisierung der proteinfamilie von soc/crac kalziumkanälen
|
|
CN1201004C
(zh)
|
1999-01-29 |
2005-05-11 |
考丽克萨有限公司 |
HER-2/neu融合蛋白
|
|
GB9905124D0
(en)
|
1999-03-05 |
1999-04-28 |
Smithkline Beecham Biolog |
Novel compounds
|
|
US7109292B2
(en)
|
1999-03-08 |
2006-09-19 |
Genentech, Inc. |
Secreted and transmembrane polypeptides and nucleic acids encoding the same
|
|
AU3395900A
(en)
|
1999-03-12 |
2000-10-04 |
Human Genome Sciences, Inc. |
Human lung cancer associated gene sequences and polypeptides
|
|
US7312303B2
(en)
|
1999-05-11 |
2007-12-25 |
Genentech, Inc. |
Anti-PRO4980 antibodies
|
|
US6268488B1
(en)
|
1999-05-25 |
2001-07-31 |
Barbas, Iii Carlos F. |
Prodrug activation using catalytic antibodies
|
|
US20060073150A1
(en)
|
2001-09-06 |
2006-04-06 |
Mary Faris |
Nucleic acid and corresponding protein entitled STEAP-1 useful in treatment and detection of cancer
|
|
AU4952600A
(en)
|
1999-06-03 |
2000-12-28 |
Takeda Chemical Industries Ltd. |
Screening method with the use of cd100
|
|
EP2977063A1
(en)
|
1999-06-25 |
2016-01-27 |
Genentech, Inc. |
Methods of treatment using anti-ErbB antibody-maytansinoid conjugates
|
|
US6302318B1
(en)
|
1999-06-29 |
2001-10-16 |
General Electric Company |
Method of providing wear-resistant coatings, and related articles
|
|
US20030119113A1
(en)
|
1999-07-20 |
2003-06-26 |
Genentech, Inc. |
Secreted and transmembrane polypeptides and nucleic acids encoding the same
|
|
US7297770B2
(en)
|
1999-08-10 |
2007-11-20 |
Genentech, Inc. |
PRO6496 polypeptides
|
|
US7294696B2
(en)
|
1999-08-17 |
2007-11-13 |
Genentech Inc. |
PRO7168 polypeptides
|
|
US6909006B1
(en)
|
1999-08-27 |
2005-06-21 |
Spirogen Limited |
Cyclopropylindole derivatives
|
|
EP1208202A2
(en)
|
1999-09-01 |
2002-05-29 |
Genentech, Inc. |
Secreted and transmembrane polypeptides and nucleic acids encoding the same
|
|
US20030129192A1
(en)
|
1999-09-10 |
2003-07-10 |
Corixa Corporation |
Compositions and methods for the therapy and diagnosis of ovarian cancer
|
|
US20030206918A1
(en)
|
1999-09-10 |
2003-11-06 |
Corixa Corporation |
Compositions and methods for the therapy and diagnosis of ovarian cancer
|
|
US20030232056A1
(en)
|
1999-09-10 |
2003-12-18 |
Corixa Corporation |
Compositions and methods for the therapy and diagnosis of ovarian cancer
|
|
DK1226177T3
(da)
|
1999-10-29 |
2008-10-06 |
Genentech Inc |
Antistofsammensætninger mod anti-prostata stamcelle-antigen (PSCA) og anvendelser deraf
|
|
HK1049843B
(en)
|
1999-11-29 |
2017-03-31 |
The Trustees Of Columbia University In The City Of New York |
Isolation of five novel genes coding for new fc receptors-type melanoma involved in the pathogenesis of lymphoma/melanoma
|
|
EP1248800A2
(en)
|
1999-11-30 |
2002-10-16 |
Corixa Corporation |
Compositions and methods for therapy and diagnosis of breast cancer
|
|
EP1239866A4
(en)
|
1999-12-10 |
2005-02-09 |
Epimmune Inc |
INDUCTION OF HER2 / NEU CELLULAR IMMUNE RESPONSES USING PEPTIDE AND NUCLEIC ACID-CONTAINING COMPOSITIONS
|
|
NZ502058A
(en)
|
1999-12-23 |
2003-11-28 |
Ovita Ltd |
Isolated mutated nucleic acid molecule for regulation of ovulation rate
|
|
US6610286B2
(en)
|
1999-12-23 |
2003-08-26 |
Zymogenetics, Inc. |
Method for treating inflammation using soluble receptors to interleukin-20
|
|
CA2395539C
(en)
|
1999-12-23 |
2009-08-25 |
Zymogenetics, Inc. |
Soluble interleukin-20 receptor
|
|
ATE459369T1
(de)
|
1999-12-23 |
2010-03-15 |
Zymogenetics Inc |
Verfahren zur behandlung von entzündungen
|
|
WO2001045746A2
(en)
|
1999-12-24 |
2001-06-28 |
Genentech, Inc. |
Methods and compositions for prolonging elimination half-times of bioactive compounds
|
|
US20040001827A1
(en)
|
2002-06-28 |
2004-01-01 |
Dennis Mark S. |
Serum albumin binding peptides for tumor targeting
|
|
US7297333B2
(en)
|
2000-01-20 |
2007-11-20 |
Genentech, Inc. |
Anti-PRO10268 antibodies
|
|
US20020039573A1
(en)
|
2000-01-21 |
2002-04-04 |
Cheever Martin A. |
Compounds and methods for prevention and treatment of HER-2/neu associated malignancies
|
|
US20030224379A1
(en)
|
2000-01-21 |
2003-12-04 |
Tang Y. Tom |
Novel nucleic acids and polypeptides
|
|
US20030104562A1
(en)
|
2000-02-11 |
2003-06-05 |
Genentech, Inc. |
Secreted and transmembrane polypeptides and nucleic acids encoding the same
|
|
US20030219806A1
(en)
|
2000-02-22 |
2003-11-27 |
Millennium Pharmaceuticals, Inc. |
Novel 18607, 15603, 69318, 12303, 48000, 52920, 5433, 38554, 57301, 58324, 55063, 52991, 59914, 59921 and 33751 molecules and uses therefor
|
|
US20020142377A1
(en)
|
2000-02-22 |
2002-10-03 |
Glucksmann Maria Alexandra |
18607, a novel human calcium channel
|
|
US20040052793A1
(en)
|
2001-02-22 |
2004-03-18 |
Carter Paul J. |
Caspase activivated prodrugs therapy
|
|
US20040002068A1
(en)
|
2000-03-01 |
2004-01-01 |
Corixa Corporation |
Compositions and methods for the detection, diagnosis and therapy of hematological malignancies
|
|
US20040005561A1
(en)
|
2000-03-01 |
2004-01-08 |
Corixa Corporation |
Compositions and methods for the detection, diagnosis and therapy of hematological malignancies
|
|
EP1261743A2
(en)
|
2000-03-07 |
2002-12-04 |
Hyseq, Inc. |
Novel nucleic acids and polypeptides
|
|
JP2004521602A
(ja)
|
2000-03-24 |
2004-07-22 |
ファハリ サッチオグリュ |
前立腺特異的または精巣特異的な新規の核酸分子、ポリペプチド、ならびに診断法および治療法
|
|
WO2001072830A2
(de)
|
2000-03-31 |
2001-10-04 |
Ipf Pharmaceuticals Gmbh |
Diagnostik- und arzneimittel zur untersuchung des zelloberflächenproteoms von tumor- und entzündungszellen sowie zur behandlung von tumorerkrankungen und entzündlichen erkrankungen vorzugsweise mit hilfe einer spezifischen chemokinrezeptor-analyse und der chemokinrezeptor-ligand-interaktion
|
|
US7279294B2
(en)
|
2000-04-03 |
2007-10-09 |
The United States Of America As Represented By The Secretary, Dept. Of Health And Human Services, Nih |
Tumor markers in ovarian cancer
|
|
MXPA02009902A
(es)
|
2000-04-07 |
2003-06-17 |
Arena Pharm Inc |
Receptores acoplados a proteina g, conocidos, activados constitutivamente, no endogenos.
|
|
WO2001088133A2
(en)
|
2000-05-18 |
2001-11-22 |
Lexicon Genetics Incorporated |
Human semaphorin homologs and polynucleotides encoding the same
|
|
AU2001274888A1
(en)
|
2000-05-19 |
2001-12-03 |
Human Genome Sciences, Inc. |
Nucleic acids, proteins, and antibodies
|
|
US20020051990A1
(en)
|
2000-06-09 |
2002-05-02 |
Eric Ople |
Novel gene targets and ligands that bind thereto for treatment and diagnosis of ovarian carcinomas
|
|
EP1297130A2
(en)
|
2000-06-16 |
2003-04-02 |
Incyte Genomics, Inc. |
G-protein coupled receptors
|
|
EP1383892A2
(en)
|
2000-06-30 |
2004-01-28 |
Incyte Genomics, Inc. |
Human extracellular matrix and cell adhesion polypeptides
|
|
EP1301524A1
(en)
|
2000-06-30 |
2003-04-16 |
Human Genome Sciences, Inc. |
B7-like polynucleotides, polypeptides, and antibodies
|
|
AU2001273194A1
(en)
|
2000-06-30 |
2002-01-14 |
Amgen Inc. |
B7-Like Molecules and Uses Thereof
|
|
WO2002006339A2
(en)
|
2000-07-03 |
2002-01-24 |
Curagen Corporation |
Proteins and nucleic acids encoding same
|
|
US20040044179A1
(en)
|
2000-07-25 |
2004-03-04 |
Genentech, Inc. |
Secreted and transmembrane polypeptides and nucleic acids encoding the same
|
|
WO2002010187A1
(en)
|
2000-07-27 |
2002-02-07 |
Mayo Foundation For Medical Education And Research |
B7-h3 and b7-h4, novel immunoregulatory molecules
|
|
US7205108B2
(en)
|
2000-07-28 |
2007-04-17 |
Ulrich Wissenbach |
Trp8, Trp9 and Trp10, novel markers for cancer
|
|
US7229623B1
(en)
|
2000-08-03 |
2007-06-12 |
Corixa Corporation |
Her-2/neu fusion proteins
|
|
KR20030048009A
(ko)
|
2000-08-14 |
2003-06-18 |
코릭사 코포레이션 |
Her-2/neu 관련 악성 종양의 치료 및 진단용 조성물및 방법
|
|
WO2002013847A2
(en)
|
2000-08-14 |
2002-02-21 |
Corixa Corporation |
Methods for diagnosis and therapy of hematological and virus-associated malignancies
|
|
GB0020953D0
(en)
|
2000-08-24 |
2000-10-11 |
Smithkline Beecham Biolog |
Vaccine
|
|
AU2001270118A1
(en)
|
2000-08-24 |
2002-03-04 |
Genentech, Inc. |
Compositions and methods for the diagnosis and treatment of tumor
|
|
WO2002022660A2
(en)
|
2000-09-11 |
2002-03-21 |
Hyseq, Inc. |
Novel nucleic acids and polypeptides
|
|
US6613567B1
(en)
|
2000-09-15 |
2003-09-02 |
Isis Pharmaceuticals, Inc. |
Antisense inhibition of Her-2 expression
|
|
ES2267814T3
(es)
|
2000-09-15 |
2007-03-16 |
Zymogenetics, Inc. |
Metodo para tratar la inflamacion.
|
|
US7491797B2
(en)
|
2000-09-15 |
2009-02-17 |
Genentech, Inc. |
PRO6308 polypeptide
|
|
UA83458C2
(uk)
|
2000-09-18 |
2008-07-25 |
Байоджен Айдек Ма Інк. |
Виділений поліпептид baff-r (рецептор фактора активації в-клітин сімейства tnf)
|
|
AU9272401A
(en)
|
2000-09-18 |
2002-03-26 |
Biogen Inc |
Cripto mutant and uses thereof
|
|
JP5010089B2
(ja)
|
2000-09-19 |
2012-08-29 |
スピロジェン リミテッド |
Cc−1065およびデュオカルマイシンのアキラルアナログの組成物およびその使用方法
|
|
EP1474528A4
(en)
|
2000-10-13 |
2006-06-14 |
Protein Design Labs Inc |
METHODS FOR DIAGNOSING PROSTATE CANCER, COMPOSITIONS AND METHODS FOR SCREENING PROSTATE CANCER MODULATORS
|
|
ATE432986T1
(de)
|
2000-11-07 |
2009-06-15 |
Zymogenetics Inc |
Menschlicher rezeptor für tumor necrosis factor
|
|
US20020150573A1
(en)
|
2000-11-10 |
2002-10-17 |
The Rockefeller University |
Anti-Igalpha-Igbeta antibody for lymphoma therapy
|
|
US20040018194A1
(en)
|
2000-11-28 |
2004-01-29 |
Francisco Joseph A. |
Recombinant anti-CD30 antibodies and uses thereof
|
|
WO2002061087A2
(en)
|
2000-12-19 |
2002-08-08 |
Lifespan Biosciences, Inc. |
Antigenic peptides, such as for g protein-coupled receptors (gpcrs), antibodies thereto, and systems for identifying such antigenic peptides
|
|
AU2002243495A1
(en)
|
2001-01-12 |
2002-07-24 |
University Of Medicine And Dentistry Of New Jersey |
Bone morphogenetic protein-2 in the treatment and diagnosis of cancer
|
|
US20030119125A1
(en)
|
2001-01-16 |
2003-06-26 |
Genentech, Inc. |
Secreted and transmembrane polypeptides and nucleic acids encoding the same
|
|
US20030119126A1
(en)
|
2001-01-16 |
2003-06-26 |
Genentech, Inc. |
Secreted and transmembrane polypeptides and nucleic acids encoding the same
|
|
US7754208B2
(en)
|
2001-01-17 |
2010-07-13 |
Trubion Pharmaceuticals, Inc. |
Binding domain-immunoglobulin fusion proteins
|
|
MXPA03006617A
(es)
|
2001-01-24 |
2004-12-02 |
Protein Design Labs Inc |
Metodos de diagnostico de cancer de pecho, composiciones y metodos de rastreo de moduladores de cancer de pecho.
|
|
WO2002060317A2
(en)
|
2001-01-30 |
2002-08-08 |
Corixa Corporation |
Compositions and methods for the therapy and diagnosis of pancreatic cancer
|
|
US20040170994A1
(en)
|
2001-02-12 |
2004-09-02 |
Callen David Frederick |
DNA sequences for human tumour suppressor genes
|
|
US20030087250A1
(en)
|
2001-03-14 |
2003-05-08 |
Millennium Pharmaceuticals, Inc. |
Nucleic acid molecules and proteins for the identification, assessment, prevention, and therapy of ovarian cancer
|
|
EP1243276A1
(en)
|
2001-03-23 |
2002-09-25 |
Franciscus Marinus Hendrikus De Groot |
Elongated and multiple spacers containing activatible prodrugs
|
|
US20040236091A1
(en)
|
2001-03-28 |
2004-11-25 |
Chicz Roman M. |
Translational profiling
|
|
US6362331B1
(en)
|
2001-03-30 |
2002-03-26 |
Council Of Scientific And Industrial Research |
Process for the preparation of antitumor agents
|
|
WO2003008537A2
(en)
|
2001-04-06 |
2003-01-30 |
Mannkind Corporation |
Epitope sequences
|
|
US6820011B2
(en)
|
2001-04-11 |
2004-11-16 |
The Regents Of The University Of Colorado |
Three-dimensional structure of complement receptor type 2 and uses thereof
|
|
AU2002254615A1
(en)
|
2001-04-17 |
2002-10-28 |
The Board Of Trustees Of The University Of Arkansas |
Repeat sequences of the ca125 gene and their use for diagnostic and therapeutic interventions
|
|
AU2002309583A1
(en)
|
2001-04-18 |
2002-11-05 |
Protein Desing Labs, Inc. |
Methods of diagnosis of lung cancer, compositions and methods of screening for modulators of lung cancer
|
|
SK14432003A3
(sk)
|
2001-04-26 |
2004-07-07 |
Biogen, Inc. |
Protilátka špecifická pre Cripto, kompozícia obsahujúca takúto protilátku a jej použitie
|
|
US6884869B2
(en)
|
2001-04-30 |
2005-04-26 |
Seattle Genetics, Inc. |
Pentapeptide compounds and uses related thereto
|
|
CA2446788A1
(en)
|
2001-05-09 |
2002-11-14 |
Corixa Corporation |
Compositions and methods for the therapy and diagnosis of prostate cancer
|
|
WO2002092836A2
(en)
|
2001-05-11 |
2002-11-21 |
Sloan-Kettering Institute For Cancer Research |
Nucleic acid sequence encoding ovarian antigen, ca125, and uses thereof
|
|
DK1436003T3
(da)
|
2001-05-24 |
2010-03-15 |
Zymogenetics Inc |
TACI-immunoglobulin-fusionsproteiner
|
|
US7157558B2
(en)
|
2001-06-01 |
2007-01-02 |
Genentech, Inc. |
Polypeptide encoded by a polynucleotide overexpresses in tumors
|
|
JP2005518185A
(ja)
|
2001-06-04 |
2005-06-23 |
キュラジェン コーポレイション |
新規タンパク質およびそれをコード化する核酸
|
|
AU2002314901A1
(en)
|
2001-06-04 |
2002-12-16 |
Eos Biotechnology, Inc. |
Methods of diagnosis and treatment of androgen-dependent prostate cancer, prostate cancer undergoing androgen-withdrawal, and androgen-independent prostate cancer
|
|
JP2005505257A
(ja)
|
2001-06-05 |
2005-02-24 |
エクセリクシス・インコーポレイテッド |
p53経路のモディファイヤーとしてのIGsおよび使用方法
|
|
ATE483976T1
(de)
|
2001-06-05 |
2010-10-15 |
Exelixis Inc |
Gfats als modifikatoren des p53-wegs und verwendungsverfahren
|
|
US7235358B2
(en)
|
2001-06-08 |
2007-06-26 |
Expression Diagnostics, Inc. |
Methods and compositions for diagnosing and monitoring transplant rejection
|
|
WO2002101075A2
(en)
|
2001-06-13 |
2002-12-19 |
Millennium Pharmaceuticals, Inc. |
Novel genes, compositions, kits, and methods for identification, assessment, prevention, and therapy of cervical cancer
|
|
US7189507B2
(en)
|
2001-06-18 |
2007-03-13 |
Pdl Biopharma, Inc. |
Methods of diagnosis of ovarian cancer, compositions and methods of screening for modulators of ovarian cancer
|
|
JP2005508144A
(ja)
|
2001-06-18 |
2005-03-31 |
イオス バイオテクノロジー,インコーポレイティド |
卵巣癌の診断方法、卵巣癌のモジュレーターをスクリーニングする組成物及び方法
|
|
US7705120B2
(en)
|
2001-06-21 |
2010-04-27 |
Millennium Pharmaceuticals, Inc. |
Compositions, kits, and methods for identification, assessment, prevention, and therapy of breast cancer
|
|
US20030108958A1
(en)
|
2001-06-28 |
2003-06-12 |
Rene De Waal Malefyt |
Biological activity of AK155
|
|
AU2002314433A1
(en)
|
2001-07-02 |
2003-01-21 |
Licentia Ltd. |
Ephrin-tie receptor materials and methods
|
|
US20040076955A1
(en)
|
2001-07-03 |
2004-04-22 |
Eos Biotechnology, Inc. |
Methods of diagnosis of bladder cancer, compositions and methods of screening for modulators of bladder cancer
|
|
WO2003003984A2
(en)
|
2001-07-05 |
2003-01-16 |
Curagen Corporation |
Novel proteins and nucleic acids encoding same
|
|
WO2003055439A2
(en)
|
2001-07-18 |
2003-07-10 |
The Regents Of The University Of California |
Her2/neu target antigen and use of same to stimulate an immune response
|
|
AU2002337657A1
(en)
|
2001-07-25 |
2003-02-17 |
Millennium Pharmaceuticals, Inc. |
Novel genes, compositions, kits, and methods for identification, assessment, prevention, and therapy of prostate cancer
|
|
KR20040019105A
(ko)
|
2001-08-03 |
2004-03-04 |
제넨테크, 인크. |
TACIs 및 BR3 폴리펩티드 및 이의 용도
|
|
AU2002324700A1
(en)
|
2001-08-14 |
2003-03-03 |
Bayer Ag |
Nucleic acid and amino acid sequences involved in pain
|
|
US20030092013A1
(en)
|
2001-08-16 |
2003-05-15 |
Vitivity, Inc. |
Diagnosis and treatment of vascular disease
|
|
AU2002313559A1
(en)
|
2001-08-23 |
2003-03-10 |
Oxford Biomedica (Uk) Limited |
Genes
|
|
AU2002357643A1
(en)
|
2001-08-29 |
2003-04-14 |
Vanderbilt University |
The human mob-5 (il-24) receptors and uses thereof
|
|
US20030124579A1
(en)
|
2001-09-05 |
2003-07-03 |
Eos Biotechnology, Inc. |
Methods of diagnosis of ovarian cancer, compositions and methods of screening for modulators of ovarian cancer
|
|
EP1434881A4
(en)
|
2001-09-17 |
2005-10-26 |
Protein Design Labs Inc |
METHOD FOR DIAGNOSIS OF CANCER COMPOSITIONS AND METHOD FOR SCREENING ON CANCER MODULATORS
|
|
WO2003025228A1
(en)
|
2001-09-18 |
2003-03-27 |
Proteologics, Inc. |
Methods and compositions for treating hcap associated diseases
|
|
KR101008758B1
(ko)
|
2001-09-18 |
2011-01-14 |
제넨테크, 인크. |
종양의 진단 및 치료를 위한 방법 및 이를 위한 조성물
|
|
WO2003025148A2
(en)
|
2001-09-19 |
2003-03-27 |
Nuvelo, Inc. |
Novel nucleic acids and polypeptides
|
|
WO2003026577A2
(en)
|
2001-09-24 |
2003-04-03 |
Seattle Genetics, Inc. |
P-amidobenzylethers in drug delivery agents
|
|
US7091186B2
(en)
|
2001-09-24 |
2006-08-15 |
Seattle Genetics, Inc. |
p-Amidobenzylethers in drug delivery agents
|
|
WO2003026493A2
(en)
|
2001-09-28 |
2003-04-03 |
Bing Yang |
Diagnosis and treatment of diseases caused by mutations in cd72
|
|
AU2002362436A1
(en)
|
2001-10-03 |
2003-04-14 |
Rigel Pharmaceuticals, Inc. |
Modulators of lymphocyte activation and migration
|
|
AU2002362454A1
(en)
|
2001-10-03 |
2003-04-14 |
Origene Technologies, Inc. |
Regulated breast cancer genes
|
|
AU2002351505B2
(en)
|
2001-10-19 |
2008-04-03 |
Genentech, Inc. |
Compositions and methods for the diagnosis and treatment of inflammatory bowel disorders
|
|
US20050123925A1
(en)
|
2002-11-15 |
2005-06-09 |
Genentech, Inc. |
Compositions and methods for the diagnosis and treatment of tumor
|
|
US7825089B2
(en)
|
2001-10-24 |
2010-11-02 |
National Jewish Health |
Three-dimensional structures of TALL-1 and its cognate receptors and modified proteins and methods related thereto
|
|
CN1685055A
(zh)
|
2001-10-31 |
2005-10-19 |
爱尔康公司 |
骨形态发生蛋白(bmp)、bmp受体和bmp结合蛋白及它们在诊断和治疗青光眼中的用途
|
|
US20030232350A1
(en)
|
2001-11-13 |
2003-12-18 |
Eos Biotechnology, Inc. |
Methods of diagnosis of cancer, compositions and methods of screening for modulators of cancer
|
|
WO2003042661A2
(en)
|
2001-11-13 |
2003-05-22 |
Protein Design Labs, Inc. |
Methods of diagnosis of cancer, compositions and methods of screening for modulators of cancer
|
|
WO2003043583A2
(en)
|
2001-11-20 |
2003-05-30 |
Seattle Genetics, Inc. |
Treatment of immunological disorders using anti-cd30 antibodies
|
|
EP1448226A1
(en)
|
2001-11-29 |
2004-08-25 |
Genset S.A. |
Agonists and antagonists of prolixin for the treatment of metabolic disorders
|
|
ES2384100T3
(es)
|
2001-12-03 |
2012-06-29 |
Alexion Pharmaceuticals, Inc. |
Método para producir anticuerpos híbridos
|
|
AU2002349784A1
(en)
|
2001-12-03 |
2003-06-17 |
Asahi Kasei Pharma Corporation |
Nf-kappab activating genes
|
|
CA2469941A1
(en)
|
2001-12-10 |
2003-07-03 |
Nuvelo, Inc. |
Novel nucleic acids and polypeptides
|
|
US20030134790A1
(en)
|
2002-01-11 |
2003-07-17 |
University Of Medicine And Dentistry Of New Jersey |
Bone Morphogenetic Protein-2 And Bone Morphogenetic Protein-4 In The Treatment And Diagnosis Of Cancer
|
|
US20050041271A1
(en)
|
2002-01-16 |
2005-02-24 |
Ito Tomoyoshi |
Moving image holography reproducing device and color moving image holography reproducing device
|
|
US7452675B2
(en)
|
2002-01-25 |
2008-11-18 |
The Queen's Medical Center |
Methods of screening for TRPM4b modulators
|
|
CN1646161A
(zh)
|
2002-02-21 |
2005-07-27 |
杜克大学 |
自身免疫疾病的药剂和治疗方法
|
|
WO2003072035A2
(en)
|
2002-02-22 |
2003-09-04 |
Genentech, Inc. |
Compositions and methods for the treatment of immune related diseases
|
|
US20030219795A1
(en)
|
2002-03-01 |
2003-11-27 |
Marcia Belvin |
SCDs as modifiers of the p53 pathway and methods of use
|
|
WO2003097803A2
(en)
|
2002-05-15 |
2003-11-27 |
Avalon Pharmaceuticals |
Cancer-linked gene as target for chemotherapy
|
|
US6660856B2
(en)
|
2002-03-08 |
2003-12-09 |
Kaohsiung Medical University |
Synthesis of pyrrolo[2,1-c][1,4]benzodiazepine analogues
|
|
EP2258712A3
(en)
|
2002-03-15 |
2011-05-04 |
Multicell Immunotherapeutics, Inc. |
Compositions and Methods to Initiate or Enhance Antibody and Major-histocompatibility Class I or Class II-restricted T Cell Responses by Using Immunomodulatory, Non-coding RNA Motifs
|
|
CA2486490A1
(en)
|
2002-03-19 |
2003-12-31 |
Curagen Corporation |
Therapeutic polypeptides, nucleic acids encoding same, and methods of use
|
|
WO2003081210A2
(en)
|
2002-03-21 |
2003-10-02 |
Sunesis Pharmaceuticals, Inc. |
Identification of kinase inhibitors
|
|
US7193069B2
(en)
|
2002-03-22 |
2007-03-20 |
Research Association For Biotechnology |
Full-length cDNA
|
|
JP2005520566A
(ja)
|
2002-03-22 |
2005-07-14 |
バイオジェン・アイデック・エムエイ・インコーポレイテッド |
Cripto特異的抗体
|
|
CA2480404A1
(en)
|
2002-03-25 |
2003-10-30 |
Uab Research Foundation |
Fc receptor homolog, reagents, and uses thereof
|
|
WO2003083074A2
(en)
|
2002-03-28 |
2003-10-09 |
Idec Pharmaceuticals Corporation |
Novel gene targets and ligands that bind thereto for treatment and diagnosis of colon carcinomas
|
|
US20030194704A1
(en)
|
2002-04-03 |
2003-10-16 |
Penn Sharron Gaynor |
Human genome-derived single exon nucleic acid probes useful for gene expression analysis two
|
|
WO2003087306A2
(en)
|
2002-04-05 |
2003-10-23 |
Agensys, Inc. |
Nucleic acid and corresponding protein entitled 98p4b6 useful in treatment and detection of cancer
|
|
US20040101874A1
(en)
|
2002-04-12 |
2004-05-27 |
Mitokor Inc. |
Targets for therapeutic intervention identified in the mitochondrial proteome
|
|
NZ535925A
(en)
|
2002-04-16 |
2008-06-30 |
Genentech Inc |
An isolated antibody that binds to a particular polypeptide
|
|
AU2003239158A1
(en)
|
2002-04-17 |
2003-11-03 |
Baylor College Of Medicine |
Aib1 as a prognostic marker and predictor of resistance to encocrine therapy
|
|
WO2003093444A2
(en)
|
2002-05-03 |
2003-11-13 |
Incyte Corporation |
Transporters and ion channels
|
|
AU2003232453A1
(en)
|
2002-05-30 |
2003-12-19 |
David K. Bol |
Human solute carrier family 7 member 11 (hslc7a11)
|
|
EP1575492A4
(en)
|
2002-06-04 |
2007-05-09 |
Avalon Pharmaceuticals |
GENERAL ASSOCIATED WITH CANCER AS TARGET FOR CHEMOTHERAPY
|
|
AU2003240495A1
(en)
|
2002-06-04 |
2003-12-19 |
Incyte Corporation |
Diagnostics markers for lung cancer
|
|
EP2233572A3
(en)
|
2002-06-06 |
2011-01-12 |
Oncotherapy Science, Inc. |
Genes and polypeptides relating to human colon cancers
|
|
AU2003242633A1
(en)
|
2002-06-06 |
2003-12-22 |
Molecular Engines Laboratories |
Dudulin genes, non-human animal model: uses in human hematological disease
|
|
US20060228705A1
(en)
|
2002-06-07 |
2006-10-12 |
Reinhard Ebner |
Cancer-linked gene as target for chemotherapy
|
|
WO2003105758A2
(en)
|
2002-06-12 |
2003-12-24 |
Avalon Pharmaceuticals, Inc. |
Cancer-linked gene as target for chemotherapy
|
|
US20040249130A1
(en)
|
2002-06-18 |
2004-12-09 |
Martin Stanton |
Aptamer-toxin molecules and methods for using same
|
|
CA2487809A1
(en)
|
2002-06-18 |
2003-12-24 |
Archemix Corp. |
Aptamer-toxin molecules and methods for using same
|
|
EP1539218A4
(en)
|
2002-06-20 |
2007-08-22 |
Univ California |
COMPOSITIONS AND METHODS FOR MODULATING LYMPHOCYTE ACTIVITY
|
|
US20060275287A1
(en)
|
2002-06-21 |
2006-12-07 |
Brad St Croix |
Scroll compressor
|
|
DE10229834A1
(de)
|
2002-07-03 |
2004-01-29 |
Zinser Textilmaschinen Gmbh |
Streckwerk für Spinnmaschinen mit nachgeordneter Verdichtungsvorrichtung
|
|
WO2004009622A2
(en)
|
2002-07-19 |
2004-01-29 |
Cellzome Ag |
Protein complexes of cellular networks underlying the development of cancer and other diseases
|
|
AU2003256836A1
(en)
|
2002-07-25 |
2004-02-16 |
Genentech, Inc. |
Taci antibodies and uses thereof
|
|
CA2494104A1
(en)
|
2002-07-31 |
2004-04-22 |
Seattle Genetics, Inc. |
Anti-cd20 antibody-drug conjugates for the treatment of cancer and immune disorders
|
|
CA2802205C
(en)
|
2002-07-31 |
2016-01-19 |
Seattle Genetics, Inc. |
Drug conjugates and their use for treating cancer, an autoimmune disease or an infectious disease
|
|
WO2004015426A1
(en)
|
2002-08-06 |
2004-02-19 |
Bayer Healthcare Ag |
Diagnostics and therapeutics for diseases associated with human cxc chemokine receptor 5(cxcr5)
|
|
JP2004121218A
(ja)
|
2002-08-06 |
2004-04-22 |
Jenokkusu Soyaku Kenkyusho:Kk |
気管支喘息または慢性閉塞性肺疾患の検査方法
|
|
MXPA05001933A
(es)
|
2002-08-19 |
2005-04-28 |
Genentech Inc |
Composiciones y metodos para el diagnostico y tratamiento de tumores.
|
|
EP1572957A4
(en)
|
2002-08-27 |
2007-10-10 |
Bristol Myers Squibb Pharma Co |
IDENTIFICATION OF POLYNUCLEOTIDES FOR PREDICTING THE ACTIVITY OF COMPOUNDS INTERACTING WITH AND / OR MODULATING TYROSINE KINASE PROTEINS AND / OR TYROSINE KINASE PROTEIN PATHWAYS IN MAMMARY CELLS
|
|
WO2004020595A2
(en)
|
2002-08-29 |
2004-03-11 |
Five Prime Therapeutics, Inc. |
Novel human polypeptides encoded by polynucleotides
|
|
WO2004019993A1
(en)
|
2002-08-30 |
2004-03-11 |
Ramot At Tel Aviv University Ltd. |
Self-immolative dendrimers releasing many active moieties upon a single activating event
|
|
AU2002951346A0
(en)
|
2002-09-05 |
2002-09-26 |
Garvan Institute Of Medical Research |
Diagnosis of ovarian cancer
|
|
CN1691964A
(zh)
|
2002-09-06 |
2005-11-02 |
曼康公司 |
表位序列
|
|
JP2006513702A
(ja)
|
2002-09-09 |
2006-04-27 |
ヌラ インコーポレーティッド |
Gタンパク質共役受容体およびその使用
|
|
JP2004113151A
(ja)
|
2002-09-27 |
2004-04-15 |
Sankyo Co Ltd |
癌遺伝子及びその用途
|
|
EP1554309A2
(en)
|
2002-10-03 |
2005-07-20 |
McGILL UNIVERSITY |
Antibodies and cyclic peptides which bind cea (carcinoembryonic antigen) and their use as cancer therapeutics
|
|
EP1570078A4
(en)
|
2002-10-04 |
2006-09-13 |
Van Andel Res Inst |
MOLECULAR CLASSIFICATION OF RENAL TUMORS AND DISCOVERING NEW DIAGNOSTIC MARKERS
|
|
US20040138269A1
(en)
|
2002-10-11 |
2004-07-15 |
Sugen, Inc. |
Substituted pyrroles as kinase inhibitors
|
|
EP2364716A3
(en)
|
2002-11-08 |
2012-01-11 |
Genentech, Inc. |
Compositions and methods for the treatment of natural killer cell related diseases
|
|
WO2004044178A2
(en)
|
2002-11-13 |
2004-05-27 |
Genentech, Inc. |
Methods and compositions for diagnosing dysplasia
|
|
CA2506080A1
(en)
|
2002-11-14 |
2004-05-27 |
Syntarga B.V. |
Prodrugs built as multiple self-elimination-release spacers
|
|
GB0226593D0
(en)
|
2002-11-14 |
2002-12-24 |
Consultants Ltd |
Compounds
|
|
EP2292259A3
(en)
|
2002-11-15 |
2011-03-23 |
MUSC Foundation For Research Development |
Complement receptor 2 targeted complement modulators
|
|
EA013677B1
(ru)
*
|
2002-11-15 |
2010-06-30 |
Генмаб А/С |
Человеческие моноклональные антитела против cd25 и их применение
|
|
WO2004045553A2
(en)
|
2002-11-15 |
2004-06-03 |
The Board Of Trustees Of The University Of Arkansas |
Ca125 gene and its use for diagnostic and therapeutic interventions
|
|
AU2003297300A1
(en)
|
2002-11-20 |
2004-06-15 |
Biogen Idec Inc. |
Novel gene targets and ligands that bind thereto for treatment and diagnosis of carcinomas
|
|
EP2410332A1
(en)
|
2002-11-21 |
2012-01-25 |
The University Of Utah |
Method for identifying purinergic modulators of the olfactory system
|
|
US20040253606A1
(en)
|
2002-11-26 |
2004-12-16 |
Protein Design Labs, Inc. |
Methods of detecting soft tissue sarcoma, compositions and methods of screening for soft tissue sarcoma modulators
|
|
EP1581641A4
(en)
|
2002-12-06 |
2006-11-15 |
Diadexus Inc |
COMPOSITIONS, SPREADING VARIATIONS AND METHODS RELATED TO OVARAL SPECIFIC GENES AND PROTEINS
|
|
JP2004198419A
(ja)
|
2002-12-13 |
2004-07-15 |
Bayer Healthcare Llc |
Timp1を用いた検出方法
|
|
ES2388280T3
(es)
|
2002-12-20 |
2012-10-11 |
Abbott Biotherapeutics Corp. |
Anticuerpos que reaccionan frente a GPR64 y utilización de los mismos
|
|
WO2004058309A1
(en)
|
2002-12-23 |
2004-07-15 |
Human Genome Sciences, Inc. |
Neutrokine-alpha conjugate, neutrokine-alpha complex, and uses thereof
|
|
EP1597558A2
(en)
|
2003-01-08 |
2005-11-23 |
Bristol-Myers Squibb Company |
Biomarkers and methods for determining sensitivity to epidermal growth factor receptor modulators
|
|
US20050227301A1
(en)
|
2003-01-10 |
2005-10-13 |
Polgen |
Cell cycle progression proteins
|
|
US20050181375A1
(en)
|
2003-01-10 |
2005-08-18 |
Natasha Aziz |
Novel methods of diagnosis of metastatic cancer, compositions and methods of screening for modulators of metastatic cancer
|
|
US20040171823A1
(en)
|
2003-01-14 |
2004-09-02 |
Nadler Steven G. |
Polynucleotides and polypeptides associated with the NF-kappaB pathway
|
|
EP1583821A4
(en)
|
2003-01-15 |
2007-07-18 |
Millennium Pharm Inc |
METHODS AND COMPOSITIONS FOR TREATING UROLOGICAL DISORDERS USING GENES 44390, 54181, 211, 5687, 884, 1405, 636, 4421, 5410, 30905, 2045, 16405, 18560, 2047, 33751, 52872, 14063, 20739, 32544, 43239, 44373, 51164, 53010, 16852, 1587, 2207, 22245, 2387, 52908, 69112, 14990, 18547, 115, 579
|
|
US20060228710A1
(en)
|
2003-02-14 |
2006-10-12 |
Morris David W |
Novel therapeutic targets in cancer
|
|
US20030224411A1
(en)
|
2003-03-13 |
2003-12-04 |
Stanton Lawrence W. |
Genes that are up- or down-regulated during differentiation of human embryonic stem cells
|
|
AU2003215821B2
(en)
|
2003-03-31 |
2009-04-23 |
Council Of Scientific And Industrial Research |
Non-cross-linking pyrrolo(2,1-c)(1,4)benzodiazepines as potential antitumour agents and process thereof
|
|
GB0321295D0
(en)
|
2003-09-11 |
2003-10-15 |
Spirogen Ltd |
Synthesis of protected pyrrolobenzodiazepines
|
|
ATE516288T1
(de)
|
2003-10-22 |
2011-07-15 |
Us Gov Health & Human Serv |
Pyrrolobenzodiazepinderivate, zusammensetzungen, die diese enthalten, und damit in zusammenhang stehende verfahren
|
|
GB0416511D0
(en)
|
2003-10-22 |
2004-08-25 |
Spirogen Ltd |
Pyrrolobenzodiazepines
|
|
NZ583292A
(en)
|
2003-11-06 |
2012-03-30 |
Seattle Genetics Inc |
Monomethylvaline compounds capable of conjugation to ligands
|
|
AU2005214988A1
(en)
|
2004-02-17 |
2005-09-01 |
Absalus, Inc. |
Super-humanized antibodies against respiratory syncytial virus
|
|
AU2005216251B2
(en)
|
2004-02-23 |
2011-03-10 |
Genentech, Inc. |
Heterocyclic self-immolative linkers and conjugates
|
|
GB0404578D0
(en)
|
2004-03-01 |
2004-04-07 |
Spirogen Ltd |
Pyrrolobenzodiazepines
|
|
GB0404574D0
(en)
|
2004-03-01 |
2004-04-07 |
Spirogen Ltd |
Amino acids
|
|
GB0404577D0
(en)
|
2004-03-01 |
2004-04-07 |
Spirogen Ltd |
Pyrrolobenzodiazepines
|
|
CA2558195C
(en)
|
2004-03-01 |
2012-11-06 |
Spirogen Limited |
11-hydroxy-5h-pyrrolo[2,1-c][1,4]benzodiazepin-5-one derivatives as key intermediates for the preparation of c2 substituted pyrrolobenzodiazepines
|
|
DE102004010943A1
(de)
|
2004-03-03 |
2005-09-29 |
Degussa Ag |
Verfahren zur Herstellung von N-geschützten 4-Ketprolinderivaten
|
|
JP5166861B2
(ja)
|
2004-03-09 |
2013-03-21 |
スピロゲン リミティッド |
ピロロベンゾジアゼピン
|
|
FR2869231B1
(fr)
|
2004-04-27 |
2008-03-14 |
Sod Conseils Rech Applic |
Composition therapeutique contenant au moins un derive de la pyrrolobenzodiazepine et la fludarabine
|
|
GB0410725D0
(en)
|
2004-05-13 |
2004-06-16 |
Spirogen Ltd |
Pyrrolobenzodiazepine therapeutic agents
|
|
ES2579805T3
(es)
|
2004-09-23 |
2016-08-16 |
Genentech, Inc. |
Anticuerpos y conjugados modificados por ingeniería genética con cisteína
|
|
JP2006203186A
(ja)
|
2004-12-24 |
2006-08-03 |
Showa Denko Kk |
熱電半導体合金の製造方法および熱電変換モジュールならびに熱電発電装置
|
|
CN101115771B
(zh)
|
2005-02-03 |
2013-06-05 |
安迪拓普有限公司 |
人类抗体和蛋白质
|
|
EP2511299A1
(en)
|
2005-04-19 |
2012-10-17 |
Seattle Genetics, Inc. |
Humanized anti-CD70 binding agents and uses thereof
|
|
AU2006238686B2
(en)
|
2005-04-21 |
2011-10-06 |
Medimmune Limited |
Pyrrolobenzodiazepines
|
|
ATE427949T1
(de)
|
2005-10-05 |
2009-04-15 |
Spirogen Ltd |
4-a4-(5-oxo-2,3,5,11a-tetrahydro-5h-pyrrolo a2, 1-cua1,4ubenzodiazepin-8-yloxy)-butyrylaminou-1 - pyrrol-2-carbonsaurealkylesterderivate und verwandte verbindung zur behandlung einer proliferativen erkrankung
|
|
EP1934174B1
(en)
|
2005-10-07 |
2011-04-06 |
Exelixis, Inc. |
Azetidines as mek inhibitors for the treatment of proliferative diseases
|
|
ES2365046T3
(es)
|
2005-12-30 |
2011-09-21 |
Merck Patent Gmbh |
Anticuerpos anti-cd19 con inmunogenicidad reducida.
|
|
DK1813614T3
(da)
|
2006-01-25 |
2012-01-23 |
Sanofi Sa |
Cytotoksiske midler, der omfatter nye tomaymycinderivater
|
|
CN101622276B
(zh)
|
2006-07-18 |
2015-04-22 |
赛诺菲-安万特 |
用于治疗癌症的抗epha2的拮抗抗体
|
|
ME01786B
(me)
|
2006-08-14 |
2014-09-20 |
Xencor Inc |
Optimizovana antitela usmerena na cd19
|
|
US20080112961A1
(en)
|
2006-10-09 |
2008-05-15 |
Macrogenics, Inc. |
Identification and Engineering of Antibodies with Variant Fc Regions and Methods of Using Same
|
|
EP1914242A1
(en)
|
2006-10-19 |
2008-04-23 |
Sanofi-Aventis |
Novel anti-CD38 antibodies for the treatment of cancer
|
|
ES2523915T5
(es)
|
2006-12-01 |
2022-05-26 |
Seagen Inc |
Agentes de unión a la diana variantes y usos de los mismos
|
|
JP2010516651A
(ja)
|
2007-01-17 |
2010-05-20 |
メルク セローノ ソシエテ アノニム |
Fc含有タンパク質の精製のための方法
|
|
CL2008001334A1
(es)
|
2007-05-08 |
2008-09-22 |
Genentech Inc |
Anticuerpo anti-muc16 disenado con cisteina; conjugado que lo comprende; metodo de produccion; formulacion farmaceutica que lo comprende; y su uso para tratar el cancer.
|
|
DK2019104T3
(da)
|
2007-07-19 |
2013-12-16 |
Sanofi Sa |
Cytotoksiske midler, der omfatter nye tomaymycinderivater, og terapeutisk anvendelse deraf
|
|
MY188455A
(en)
|
2007-10-19 |
2021-12-09 |
Genentech Inc |
Cysteine engineered anti-tenb2 antibodies and antibody drug conjugates
|
|
DK2842575T3
(da)
|
2008-03-18 |
2017-11-27 |
Seattle Genetics Inc |
Auristatin-lægemiddel-linker-konjugater
|
|
GB0813432D0
(en)
|
2008-07-22 |
2008-08-27 |
Spirogen Ltd |
Pyrrolobenzodiazepines
|
|
US8668695B2
(en)
|
2008-10-15 |
2014-03-11 |
Zimmer Gmbh |
Intramedullary nail
|
|
GB0819097D0
(en)
|
2008-10-17 |
2008-11-26 |
Spirogen Ltd |
Pyrrolobenzodiazepines
|
|
GB0819095D0
(en)
|
2008-10-17 |
2008-11-26 |
Spirogen Ltd |
Pyrrolobenzodiazepines
|
|
US8426402B2
(en)
|
2009-02-05 |
2013-04-23 |
Immunogen, Inc. |
Benzodiazepine derivatives
|
|
WO2010095031A2
(en)
|
2009-02-23 |
2010-08-26 |
Glenmark Pharmaceuticals S.A. |
Humanized antibodies that bind to cd19 and their uses
|
|
FR2949469A1
(fr)
|
2009-08-25 |
2011-03-04 |
Sanofi Aventis |
Derives anticancereux, leur preparation et leur application en therapeutique
|
|
TW201119673A
(en)
|
2009-09-01 |
2011-06-16 |
Abbott Lab |
Dual variable domain immunoglobulins and uses thereof
|
|
CA2775350A1
(en)
|
2009-09-24 |
2011-03-31 |
Seattle Genetics, Inc. |
Dr5 ligand drug conjugates
|
|
WO2011100227A1
(en)
|
2010-02-09 |
2011-08-18 |
Bristol-Myers Squibb Company |
Benzylpyrrolidinone derivatives as modulators of chemokine receptor activity
|
|
NZ602932A
(en)
|
2010-04-15 |
2014-08-29 |
Seattle Genetics Inc |
Targeted pyrrolobenzodiazapine conjugates
|
|
WO2011130615A2
(en)
|
2010-04-15 |
2011-10-20 |
Dr. Reddy's Laboratories Ltd. |
Preparation of lacosamide
|
|
CN102971329B
(zh)
|
2010-04-15 |
2016-06-29 |
麦迪穆有限责任公司 |
用于治疗增殖性疾病的吡咯并苯并二氮杂卓
|
|
GB201006340D0
(en)
|
2010-04-15 |
2010-06-02 |
Spirogen Ltd |
Synthesis method and intermediates
|
|
US20110256157A1
(en)
|
2010-04-15 |
2011-10-20 |
Spirogen Limited |
Pyrrolobenzodiazepines and conjugates thereof
|
|
IL279304B
(en)
|
2011-02-15 |
2022-07-01 |
Immunogen Inc |
Method for producing an indolinobenzodiazepine
|
|
CN103987718A
(zh)
|
2011-09-20 |
2014-08-13 |
斯皮罗根有限公司 |
作为非对称二聚体pbd化合物用于内含在靶向结合物中的吡咯并苯并二氮杂卓
|
|
HRP20151374T1
(hr)
|
2011-10-14 |
2016-01-15 |
Medimmune Limited |
Pirolobenzodiazepini i njihovi konjugati
|
|
JP6393617B2
(ja)
|
2011-10-14 |
2018-09-19 |
シアトル ジェネティクス,インコーポレーテッド |
ピロロベンゾジアゼピンおよび標的コンジュゲート
|
|
US9388187B2
(en)
|
2011-10-14 |
2016-07-12 |
Medimmune Limited |
Pyrrolobenzodiazepines
|
|
CA2850375C
(en)
|
2011-10-14 |
2019-07-02 |
Seattle Genetics, Inc. |
Pyrrolobenzodiazepines and targeted conjugates
|
|
CA2850103C
(en)
|
2011-10-14 |
2019-09-10 |
Spirogen Sarl |
Pyrrolobenzodiazepines
|
|
WO2013053872A1
(en)
|
2011-10-14 |
2013-04-18 |
Spirogen Sàrl |
Synthesis method and intermediates useful in the preparation of pyrrolobenzodiazepines
|
|
CA2873884A1
(en)
|
2012-07-09 |
2014-01-16 |
Genentech, Inc. |
Immunoconjugates comprising anti-cd79b antibodies
|
|
CA2873889A1
(en)
|
2012-07-09 |
2014-01-16 |
Genentech, Inc. |
Anti-cd22 antibodies and immunoconjugates
|
|
AR091961A1
(es)
|
2012-08-02 |
2015-03-11 |
Genentech Inc |
Inmunoconjugados y anticuerpos anti-etbr (receptor de endotelina b)
|
|
JP6392764B2
(ja)
|
2012-10-12 |
2018-09-19 |
エイディーシー・セラピューティクス・エス・アーAdc Therapeutics Sa |
ピロロベンゾジアゼピン−抗体結合体
|
|
CA2885305C
(en)
|
2012-10-12 |
2019-11-12 |
Spirogen Sarl |
Synthesis and intermediates of pyrrolobenzodiazepine derivatives for conjugation
|
|
WO2014057073A1
(en)
|
2012-10-12 |
2014-04-17 |
Spirogen Sàrl |
Pyrrolobenzodiazepines and conjugates thereof
|
|
HUE045435T2
(hu)
|
2012-10-12 |
2019-12-30 |
Medimmune Ltd |
Pirrolobenzodiazepinek és konjugátumaik
|
|
CN105307685B
(zh)
|
2013-03-13 |
2019-03-08 |
麦迪穆有限责任公司 |
吡咯并苯并二氮杂卓和其结合物
|
|
EP3223854A1
(en)
*
|
2014-11-25 |
2017-10-04 |
ADC Therapeutics SA |
Pyrrolobenzodiazepine-antibody conjugates
|
|
AU2018253950A1
(en)
*
|
2017-04-20 |
2019-09-19 |
Adc Therapeutics Sa |
Combination therapy with an anti-CD25 antibody-drug conjugate
|