|
US3361742A
(en)
|
1964-12-07 |
1968-01-02 |
Hoffmann La Roche |
5-oxo-1h-pyrrolo-[2, 1-c][1, 4]-benzodiazepin-2-crylamides
|
|
US3523941A
(en)
|
1967-03-06 |
1970-08-11 |
Hoffmann La Roche |
Benzodiazepine compounds and process for their preparation
|
|
US3524849A
(en)
|
1967-10-27 |
1970-08-18 |
Hoffmann La Roche |
Process for the preparation of pyrrolo-benzodiazepine acrylamides and intermediates useful therein
|
|
JPS4843755B1
(enExample)
|
1969-06-26 |
1973-12-20 |
|
|
|
IL33558A
(en)
|
1968-12-30 |
1973-10-25 |
Fujisawa Pharmaceutical Co |
Antibiotic pyrrolo-benzodiazepine compound,its derivatives and processes for their production
|
|
FR2027356A1
(en)
|
1968-12-30 |
1970-09-25 |
Fujisawa Pharmaceutical Co |
Benzodiazepinone antibiotics
|
|
JPS6053033B2
(ja)
|
1976-12-28 |
1985-11-22 |
財団法人微生物化学研究会 |
新制癌抗生物質マゼスラマイシン及びその製造方法
|
|
JPS585916B2
(ja)
|
1977-12-27 |
1983-02-02 |
株式会社ミドリ十字 |
新規ベンゾジアゼピン系化合物
|
|
JPS5615289A
(en)
|
1979-07-17 |
1981-02-14 |
Green Cross Corp:The |
Novel benzodiazepinnbased compound 3
|
|
JPS57131791A
(en)
|
1980-12-31 |
1982-08-14 |
Fujisawa Pharmaceut Co Ltd |
Benzodiazepine derivative and its preparation
|
|
CA1185602A
(en)
|
1981-02-27 |
1985-04-16 |
Emilio Kyburz |
Imidazodiazepines
|
|
CA1173441A
(en)
|
1981-02-27 |
1984-08-28 |
Hoffmann-La Roche Limited |
Imidazodiazepines
|
|
CA1184175A
(en)
|
1981-02-27 |
1985-03-19 |
Walter Hunkeler |
Imidazodiazepines
|
|
JPS58180487A
(ja)
|
1982-04-16 |
1983-10-21 |
Kyowa Hakko Kogyo Co Ltd |
抗生物質dc−81およびその製造法
|
|
US4427588A
(en)
|
1982-11-08 |
1984-01-24 |
Bristol-Myers Company |
Process for conversion of oxotomaymycin to tomaymycin
|
|
US4427587A
(en)
|
1982-11-10 |
1984-01-24 |
Bristol-Myers Company |
Total synthesis of antitumor antibiotics BBM-2040A and BBM-2040B
|
|
JPS59152329A
(ja)
|
1983-02-17 |
1984-08-31 |
Green Cross Corp:The |
局所障害抑制剤
|
|
US4816567A
(en)
|
1983-04-08 |
1989-03-28 |
Genentech, Inc. |
Recombinant immunoglobin preparations
|
|
FR2586683B1
(fr)
|
1985-08-29 |
1988-07-01 |
Centre Nat Rech Scient |
Nouveaux derives de neothramycine, leur procede de preparation et leur application en tant que medicaments
|
|
US5583024A
(en)
|
1985-12-02 |
1996-12-10 |
The Regents Of The University Of California |
Recombinant expression of Coleoptera luciferase
|
|
JP2660201B2
(ja)
|
1988-08-05 |
1997-10-08 |
塩野義製薬株式会社 |
新規ピロロ[1,4]ベンゾジアゼピン誘導体および老人性痴呆薬
|
|
CA2023779A1
(en)
|
1989-08-23 |
1991-02-24 |
Margaret D. Moore |
Compositions and methods for detection and treatment of epstein-barr virus infection and immune disorders
|
|
JPH053790A
(ja)
|
1990-04-19 |
1993-01-14 |
Fujisawa Pharmaceut Co Ltd |
デヒドロペプチダーゼ−i
|
|
US5256643A
(en)
|
1990-05-29 |
1993-10-26 |
The Government Of The United States |
Human cripto protein
|
|
WO1992007574A1
(en)
|
1990-10-25 |
1992-05-14 |
Tanox Biosystems, Inc. |
Glycoproteins associated with membrane-bound immunoglobulins as antibody targets on b cells
|
|
ATE194385T1
(de)
|
1991-03-29 |
2000-07-15 |
Genentech Inc |
Menschliche pf4a rezeptoren und ihre verwendung
|
|
US5543503A
(en)
|
1991-03-29 |
1996-08-06 |
Genentech Inc. |
Antibodies to human IL-8 type A receptor
|
|
US5440021A
(en)
|
1991-03-29 |
1995-08-08 |
Chuntharapai; Anan |
Antibodies to human IL-8 type B receptor
|
|
FR2676230B1
(fr)
|
1991-05-07 |
1993-08-27 |
Centre Nat Rech Scient |
Nouveaux derives de pyrrolo [1,4]-benzodiazepines, leur procede de preparation et medicaments les contenant.
|
|
JP3050424B2
(ja)
|
1991-07-12 |
2000-06-12 |
塩野義製薬株式会社 |
ヒトエンドセリンリセプター
|
|
US5264557A
(en)
|
1991-08-23 |
1993-11-23 |
The United States Of America As Represented By The Department Of Health And Human Services |
Polypeptide of a human cripto-related gene, CR-3
|
|
US5362852A
(en)
|
1991-09-27 |
1994-11-08 |
Pfizer Inc. |
Modified peptide derivatives conjugated at 2-hydroxyethylamine moieties
|
|
US6153408A
(en)
|
1991-11-15 |
2000-11-28 |
Institut Pasteur And Institut National De La Sante Et De La Recherche Medicale |
Altered major histocompatibility complex (MHC) determinant and methods of using the determinant
|
|
US6011146A
(en)
|
1991-11-15 |
2000-01-04 |
Institut Pasteur |
Altered major histocompatibility complex (MHC) determinant and methods of using the determinant
|
|
GB9205051D0
(en)
|
1992-03-09 |
1992-04-22 |
Cancer Res Campaign Tech |
Pyrrolobenzodiazepine derivatives,their preparation,and compositions containing them
|
|
FR2696176B1
(fr)
|
1992-09-28 |
1994-11-10 |
Synthelabo |
Dérivés de pipéridine, leur préparation et leur application en thérapeutique.
|
|
IL107366A
(en)
|
1992-10-23 |
2003-03-12 |
Chugai Pharmaceutical Co Ltd |
Genes coding for megakaryocyte potentiator
|
|
US5644033A
(en)
|
1992-12-22 |
1997-07-01 |
Health Research, Inc. |
Monoclonal antibodies that define a unique antigen of human B cell antigen receptor complex and methods of using same for diagnosis and treatment
|
|
US5801005A
(en)
|
1993-03-17 |
1998-09-01 |
University Of Washington |
Immune reactivity to HER-2/neu protein for diagnosis of malignancies in which the HER-2/neu oncogene is associated
|
|
US5869445A
(en)
|
1993-03-17 |
1999-02-09 |
University Of Washington |
Methods for eliciting or enhancing reactivity to HER-2/neu protein
|
|
US6214345B1
(en)
|
1993-05-14 |
2001-04-10 |
Bristol-Myers Squibb Co. |
Lysosomal enzyme-cleavable antitumor drug conjugates
|
|
GB9316162D0
(en)
|
1993-08-04 |
1993-09-22 |
Zeneca Ltd |
Fungicides
|
|
US5773223A
(en)
|
1993-09-02 |
1998-06-30 |
Chiron Corporation |
Endothelin B1, (ETB1) receptor polypeptide and its encoding nucleic acid methods, and uses thereof
|
|
EP0647450A1
(en)
|
1993-09-09 |
1995-04-12 |
BEHRINGWERKE Aktiengesellschaft |
Improved prodrugs for enzyme mediated activation
|
|
US5750370A
(en)
|
1995-06-06 |
1998-05-12 |
Human Genome Sciences, Inc. |
Nucleic acid encoding human endothlein-bombesin receptor and method of producing the receptor
|
|
JPH08336393A
(ja)
|
1995-04-13 |
1996-12-24 |
Mitsubishi Chem Corp |
光学活性なγ−置換−β−ヒドロキシ酪酸エステルの製造法
|
|
US5707829A
(en)
|
1995-08-11 |
1998-01-13 |
Genetics Institute, Inc. |
DNA sequences and secreted proteins encoded thereby
|
|
US20020193567A1
(en)
|
1995-08-11 |
2002-12-19 |
Genetics Institute, Inc. |
Secreted proteins and polynucleotides encoding them
|
|
JP3646191B2
(ja)
|
1996-03-19 |
2005-05-11 |
大塚製薬株式会社 |
ヒト遺伝子
|
|
US6218519B1
(en)
|
1996-04-12 |
2001-04-17 |
Pro-Neuron, Inc. |
Compounds and methods for the selective treatment of cancer and bacterial infections
|
|
EP0910636A1
(en)
|
1996-05-17 |
1999-04-28 |
Schering Corporation |
Human b-cell antigens, related reagents
|
|
AU739028B2
(en)
|
1996-09-27 |
2001-10-04 |
Bristol-Myers Squibb Company |
Hydrolyzable prodrugs for delivery of anticancer drugs to metastatic cells
|
|
US6759509B1
(en)
|
1996-11-05 |
2004-07-06 |
Bristol-Myers Squibb Company |
Branched peptide linkers
|
|
US5945511A
(en)
|
1997-02-20 |
1999-08-31 |
Zymogenetics, Inc. |
Class II cytokine receptor
|
|
US7033827B2
(en)
|
1997-02-25 |
2006-04-25 |
Corixa Corporation |
Prostate-specific polynucleotide compositions
|
|
US20030185830A1
(en)
|
1997-02-25 |
2003-10-02 |
Corixa Corporation |
Compositions and methods for the therapy and diagnosis of prostate cancer
|
|
ATE268340T1
(de)
|
1997-03-10 |
2004-06-15 |
Univ California |
Prostata stammzell-antigen (psca)
|
|
US6541212B2
(en)
|
1997-03-10 |
2003-04-01 |
The Regents Of The University Of California |
Methods for detecting prostate stem cell antigen protein
|
|
US6261791B1
(en)
|
1997-03-10 |
2001-07-17 |
The Regents Of The University Of California |
Method for diagnosing cancer using specific PSCA antibodies
|
|
US6555339B1
(en)
|
1997-04-14 |
2003-04-29 |
Arena Pharmaceuticals, Inc. |
Non-endogenous, constitutively activated human protein-coupled receptors
|
|
US6319688B1
(en)
|
1997-04-28 |
2001-11-20 |
Smithkline Beecham Corporation |
Polynucleotide encoding human sodium dependent phosphate transporter (IPT-1)
|
|
WO1998051824A1
(en)
|
1997-05-15 |
1998-11-19 |
Abbott Laboratories |
Reagents and methods useful for detecting disease of the urinary tract
|
|
US6890749B2
(en)
|
1997-05-15 |
2005-05-10 |
Abbott Laboratories |
Reagents and methods useful for detecting diseases of the prostate
|
|
US6602677B1
(en)
|
1997-09-19 |
2003-08-05 |
Promega Corporation |
Thermostable luciferases and methods of production
|
|
US20030060612A1
(en)
|
1997-10-28 |
2003-03-27 |
Genentech, Inc. |
Compositions and methods for the diagnosis and treatment of tumor
|
|
US20020034749A1
(en)
|
1997-11-18 |
2002-03-21 |
Billing-Medel Patricia A. |
Reagents and methods useful for detecting diseases of the breast
|
|
US6110695A
(en)
|
1997-12-02 |
2000-08-29 |
The Regents Of The University Of California |
Modulating the interaction of the chemokine, B Lymphocyte Hemoattractant, and its Receptor, BLR1
|
|
WO2004031238A2
(en)
|
2002-10-03 |
2004-04-15 |
Mcgill Univeristy |
Antibodies and cyclic peptides which bind cea (carcinoembryonic antigen) and their use as cancer therapeutics
|
|
WO1999046284A2
(en)
|
1998-03-13 |
1999-09-16 |
The Burnham Institute |
Molecules that home to various selected organs or tissues
|
|
WO1999058658A2
(en)
|
1998-05-13 |
1999-11-18 |
Epimmune, Inc. |
Expression vectors for stimulating an immune response and methods of using the same
|
|
TWI253935B
(en)
|
1998-05-22 |
2006-05-01 |
Daiichi Seiyaku Co |
Drug complex
|
|
US20030064397A1
(en)
|
1998-05-22 |
2003-04-03 |
Incyte Genomics, Inc. |
Transmembrane protein differentially expressed in prostate and lung tumors
|
|
US20020187472A1
(en)
|
2001-03-09 |
2002-12-12 |
Preeti Lal |
Steap-related protein
|
|
ATE349722T1
(de)
|
1998-07-08 |
2007-01-15 |
E Ink Corp |
Verbesserte farbige mikroverkapselte elektrophoretische anzeige
|
|
GB9818732D0
(en)
|
1998-08-27 |
1998-10-21 |
Univ Portsmouth |
Collection of compounds
|
|
GB9818731D0
(en)
|
1998-08-27 |
1998-10-21 |
Univ Portsmouth |
Compounds
|
|
WO2000012130A1
(en)
|
1998-08-27 |
2000-03-09 |
Smithkline Beecham Corporation |
Rp105 agonists and antagonists
|
|
NZ510493A
(en)
|
1998-08-27 |
2003-11-28 |
Spirogen Ltd |
Pyrrolobenzodiazepin-5-one derivatives for treating viral, bacterial and protozoal infections
|
|
GB9818730D0
(en)
|
1998-08-27 |
1998-10-21 |
Univ Portsmouth |
Collections of compounds
|
|
JP4689781B2
(ja)
|
1998-09-03 |
2011-05-25 |
独立行政法人科学技術振興機構 |
アミノ酸輸送蛋白及びその遺伝子
|
|
WO2000020579A1
(en)
|
1998-10-02 |
2000-04-13 |
Mcmaster University |
Spliced form of erbb-2/neu oncogene
|
|
WO2001057188A2
(en)
|
2000-02-03 |
2001-08-09 |
Hyseq, Inc. |
Novel nucleic acids and polypeptides
|
|
US20030091580A1
(en)
|
2001-06-18 |
2003-05-15 |
Mitcham Jennifer L. |
Compositions and methods for the therapy and diagnosis of ovarian cancer
|
|
US6858710B2
(en)
|
1998-12-17 |
2005-02-22 |
Corixa Corporation |
Compositions and methods for the therapy and diagnosis of ovarian cancer
|
|
US6468546B1
(en)
|
1998-12-17 |
2002-10-22 |
Corixa Corporation |
Compositions and methods for therapy and diagnosis of ovarian cancer
|
|
US20020119158A1
(en)
|
1998-12-17 |
2002-08-29 |
Corixa Corporation |
Compositions and methods for the therapy and diagnosis of ovarian cancer
|
|
US6962980B2
(en)
|
1999-09-24 |
2005-11-08 |
Corixa Corporation |
Compositions and methods for the therapy and diagnosis of ovarian cancer
|
|
WO2000040614A2
(en)
|
1998-12-30 |
2000-07-13 |
Beth Israel Deaconess Medical Center, Inc. |
Characterization of the soc/crac calcium channel protein family
|
|
CZ20012587A3
(cs)
|
1999-01-29 |
2002-05-15 |
Corixa Corporation |
Izolovaný protein, nukleová kyselina, virový vektor, farmaceutický prostředek, izolovaná populace T buněk, způsob posílení imunitní odpovědi, způsob odstranění nádorových buněk, způsob stimulace a/nebo namnoľení T buněk a způsob přípravy fúzního proteinu
|
|
GB9905124D0
(en)
|
1999-03-05 |
1999-04-28 |
Smithkline Beecham Biolog |
Novel compounds
|
|
US7109292B2
(en)
|
1999-03-08 |
2006-09-19 |
Genentech, Inc. |
Secreted and transmembrane polypeptides and nucleic acids encoding the same
|
|
AU3395900A
(en)
|
1999-03-12 |
2000-10-04 |
Human Genome Sciences, Inc. |
Human lung cancer associated gene sequences and polypeptides
|
|
US7312303B2
(en)
|
1999-05-11 |
2007-12-25 |
Genentech, Inc. |
Anti-PRO4980 antibodies
|
|
US6268488B1
(en)
|
1999-05-25 |
2001-07-31 |
Barbas, Iii Carlos F. |
Prodrug activation using catalytic antibodies
|
|
AU4952600A
(en)
|
1999-06-03 |
2000-12-28 |
Takeda Chemical Industries Ltd. |
Screening method with the use of cd100
|
|
DK2283867T3
(da)
|
1999-06-25 |
2014-06-10 |
Immunogen Inc |
Fremgangsmåder til behandling ved anvendelse af anti-ErbB antistof-maytansinoidkonjugater
|
|
US6302318B1
(en)
|
1999-06-29 |
2001-10-16 |
General Electric Company |
Method of providing wear-resistant coatings, and related articles
|
|
US20030119113A1
(en)
|
1999-07-20 |
2003-06-26 |
Genentech, Inc. |
Secreted and transmembrane polypeptides and nucleic acids encoding the same
|
|
US7297770B2
(en)
|
1999-08-10 |
2007-11-20 |
Genentech, Inc. |
PRO6496 polypeptides
|
|
US7294696B2
(en)
|
1999-08-17 |
2007-11-13 |
Genentech Inc. |
PRO7168 polypeptides
|
|
US6909006B1
(en)
|
1999-08-27 |
2005-06-21 |
Spirogen Limited |
Cyclopropylindole derivatives
|
|
CA2380355A1
(en)
|
1999-09-01 |
2001-03-08 |
Genentech, Inc. |
Secreted and transmembrane polypeptides and nucleic acids encoding the same
|
|
US20030232056A1
(en)
|
1999-09-10 |
2003-12-18 |
Corixa Corporation |
Compositions and methods for the therapy and diagnosis of ovarian cancer
|
|
US20030129192A1
(en)
|
1999-09-10 |
2003-07-10 |
Corixa Corporation |
Compositions and methods for the therapy and diagnosis of ovarian cancer
|
|
US20030206918A1
(en)
|
1999-09-10 |
2003-11-06 |
Corixa Corporation |
Compositions and methods for the therapy and diagnosis of ovarian cancer
|
|
CN1413220A
(zh)
|
1999-10-29 |
2003-04-23 |
杰南技术公司 |
抗前列腺干细胞抗原(psca)抗体组合物及其应用方法
|
|
DK1235847T3
(en)
|
1999-11-29 |
2016-03-14 |
Univ Columbia |
ISOLATION OF FIVE NOVEL GENES ENCODING NEW Fc RECEPTORS-TYPE melanoma involved in the pathogenesis OF LYMPHOMA / Melanoma
|
|
AU1807401A
(en)
|
1999-11-30 |
2001-06-12 |
Corixa Corporation |
Compositions and methods for therapy and diagnosis of breast cancer
|
|
EP1239866A4
(en)
|
1999-12-10 |
2005-02-09 |
Epimmune Inc |
INDUCTION OF HER2 / NEU CELLULAR IMMUNE RESPONSES USING PEPTIDE AND NUCLEIC ACID-CONTAINING COMPOSITIONS
|
|
US6610286B2
(en)
|
1999-12-23 |
2003-08-26 |
Zymogenetics, Inc. |
Method for treating inflammation using soluble receptors to interleukin-20
|
|
EP1246846B1
(en)
|
1999-12-23 |
2008-09-10 |
ZymoGenetics, Inc. |
Soluble interleukin-20 receptor
|
|
DE60043957D1
(de)
|
1999-12-23 |
2010-04-15 |
Zymogenetics Inc |
Verfahren zur Behandlung von Entzündungen
|
|
NZ502058A
(en)
|
1999-12-23 |
2003-11-28 |
Ovita Ltd |
Isolated mutated nucleic acid molecule for regulation of ovulation rate
|
|
US20040001827A1
(en)
|
2002-06-28 |
2004-01-01 |
Dennis Mark S. |
Serum albumin binding peptides for tumor targeting
|
|
EP2180054A1
(en)
|
1999-12-24 |
2010-04-28 |
Genentech, Inc. |
Methods and compositions for prolonging elimination half-times of bioactive compounds
|
|
US7297333B2
(en)
|
2000-01-20 |
2007-11-20 |
Genentech, Inc. |
Anti-PRO10268 antibodies
|
|
CA2398102A1
(en)
|
2000-01-21 |
2001-07-26 |
Corixa Corporation |
Compounds and methods for prevention and treatment of her-2/neu associated malignancies
|
|
US20030224379A1
(en)
|
2000-01-21 |
2003-12-04 |
Tang Y. Tom |
Novel nucleic acids and polypeptides
|
|
US20030186372A1
(en)
|
2000-02-11 |
2003-10-02 |
Genentech, Inc. |
Secreted and transmembrane polypeptides and nucleic acids encoding the same
|
|
US20030219806A1
(en)
|
2000-02-22 |
2003-11-27 |
Millennium Pharmaceuticals, Inc. |
Novel 18607, 15603, 69318, 12303, 48000, 52920, 5433, 38554, 57301, 58324, 55063, 52991, 59914, 59921 and 33751 molecules and uses therefor
|
|
AU2001238596A1
(en)
|
2000-02-22 |
2001-09-03 |
Millennium Pharmaceuticals, Inc. |
18607, a novel human calcium channel
|
|
US20040052793A1
(en)
|
2001-02-22 |
2004-03-18 |
Carter Paul J. |
Caspase activivated prodrugs therapy
|
|
US20040005561A1
(en)
|
2000-03-01 |
2004-01-08 |
Corixa Corporation |
Compositions and methods for the detection, diagnosis and therapy of hematological malignancies
|
|
US20040002068A1
(en)
|
2000-03-01 |
2004-01-01 |
Corixa Corporation |
Compositions and methods for the detection, diagnosis and therapy of hematological malignancies
|
|
EP1261743A2
(en)
|
2000-03-07 |
2002-12-04 |
Hyseq, Inc. |
Novel nucleic acids and polypeptides
|
|
CA2403637A1
(en)
|
2000-03-24 |
2001-10-04 |
Fahri Saatcioglu |
Novel prostate-specific or testis-specific nucleic acid molecules, polypeptides, and diagnostic and therapeutic methods
|
|
US20030186889A1
(en)
|
2000-03-31 |
2003-10-02 |
Wolf-Georg Forssmann |
Diagnostic and medicament for analysing the cell surface proteome of tumour and inflammatory cells and for treating tumorous and inflammatory diseases, preferably using a specific chemokine receptor analysis and the chemokine receptor-ligand interaction
|
|
US7279294B2
(en)
|
2000-04-03 |
2007-10-09 |
The United States Of America As Represented By The Secretary, Dept. Of Health And Human Services, Nih |
Tumor markers in ovarian cancer
|
|
NZ521158A
(en)
|
2000-04-07 |
2004-08-27 |
Arena Pharm Inc |
Non-endogenous, constitutively activated known G protein-coupled receptors
|
|
WO2001088133A2
(en)
|
2000-05-18 |
2001-11-22 |
Lexicon Genetics Incorporated |
Human semaphorin homologs and polynucleotides encoding the same
|
|
AU2001274888A1
(en)
|
2000-05-19 |
2001-12-03 |
Human Genome Sciences, Inc. |
Nucleic acids, proteins, and antibodies
|
|
US20020051990A1
(en)
|
2000-06-09 |
2002-05-02 |
Eric Ople |
Novel gene targets and ligands that bind thereto for treatment and diagnosis of ovarian carcinomas
|
|
JP2004523203A
(ja)
|
2000-06-16 |
2004-08-05 |
インサイト・ゲノミックス・インコーポレイテッド |
Gタンパク質結合受容体
|
|
WO2002002634A2
(en)
|
2000-06-30 |
2002-01-10 |
Incyte Genomics, Inc. |
Human extracellular matrix and cell adhesion polypeptides
|
|
WO2002002624A2
(en)
|
2000-06-30 |
2002-01-10 |
Amgen, Inc. |
B7-like molecules and uses thereof
|
|
CA2406649A1
(en)
|
2000-06-30 |
2002-01-10 |
Human Genome Sciences, Inc. |
B7-like polynucleotides, polypeptides, and antibodies
|
|
WO2002006339A2
(en)
|
2000-07-03 |
2002-01-24 |
Curagen Corporation |
Proteins and nucleic acids encoding same
|
|
US20040044179A1
(en)
|
2000-07-25 |
2004-03-04 |
Genentech, Inc. |
Secreted and transmembrane polypeptides and nucleic acids encoding the same
|
|
AU2001283507A1
(en)
|
2000-07-27 |
2002-02-13 |
Mayo Foundation For Medical Education And Research |
B7-h3 and b7-h4, novel immunoregulatory molecules
|
|
ATE396266T1
(de)
|
2000-07-28 |
2008-06-15 |
Ulrich Wissenbach |
Trp8 krebsmarker
|
|
US7229623B1
(en)
|
2000-08-03 |
2007-06-12 |
Corixa Corporation |
Her-2/neu fusion proteins
|
|
EP1366153A2
(en)
|
2000-08-14 |
2003-12-03 |
Corixa Corporation |
Compositions and methods for the therapy and diagnosis of her-2/neu-associated malignancies
|
|
WO2002013847A2
(en)
|
2000-08-14 |
2002-02-21 |
Corixa Corporation |
Methods for diagnosis and therapy of hematological and virus-associated malignancies
|
|
EP1445318A2
(en)
|
2000-08-24 |
2004-08-11 |
Genetech, Inc. |
Compositions and methods for the diagnosis and treatment of tumor
|
|
GB0020953D0
(en)
|
2000-08-24 |
2000-10-11 |
Smithkline Beecham Biolog |
Vaccine
|
|
AU2001290548A1
(en)
|
2000-09-11 |
2002-03-26 |
Hyseq, Inc. |
Novel nucleic acids and polypeptides
|
|
DE60141546D1
(de)
|
2000-09-15 |
2010-04-22 |
Zymogenetics Inc |
Polypeptide enthaltend extrazellulären Domäne von IL-20RA und/oderr IL-20RB
|
|
US6613567B1
(en)
|
2000-09-15 |
2003-09-02 |
Isis Pharmaceuticals, Inc. |
Antisense inhibition of Her-2 expression
|
|
US20030119121A1
(en)
|
2000-09-15 |
2003-06-26 |
Genentech, Inc. |
Secreted and transmembrane polypeptides and nucleic acids encoding the same
|
|
JP2004524810A
(ja)
|
2000-09-18 |
2004-08-19 |
バイオジェン・アイデック・エムエイ・インコーポレイテッド |
Cripto変異体およびその使用
|
|
UA83458C2
(uk)
|
2000-09-18 |
2008-07-25 |
Байоджен Айдек Ма Інк. |
Виділений поліпептид baff-r (рецептор фактора активації в-клітин сімейства tnf)
|
|
WO2002030894A2
(en)
|
2000-09-19 |
2002-04-18 |
Taiho Pharmaceutical Co., Ltd. |
Compositions and methods of the use thereof achiral analogues of cc-1065 and the duocarmycins
|
|
AU2002215345A1
(en)
|
2000-10-13 |
2002-04-22 |
Eos Biotechnology, Inc. |
Methods of diagnosis of prostate cancer, compositions and methods of screening for modulators of prostate cancer
|
|
CA2428242A1
(en)
|
2000-11-07 |
2002-05-16 |
Zymogenetics, Inc. |
Human tumor necrosis factor receptor
|
|
US20020150573A1
(en)
|
2000-11-10 |
2002-10-17 |
The Rockefeller University |
Anti-Igalpha-Igbeta antibody for lymphoma therapy
|
|
US20040018194A1
(en)
|
2000-11-28 |
2004-01-29 |
Francisco Joseph A. |
Recombinant anti-CD30 antibodies and uses thereof
|
|
WO2002061087A2
(en)
|
2000-12-19 |
2002-08-08 |
Lifespan Biosciences, Inc. |
Antigenic peptides, such as for g protein-coupled receptors (gpcrs), antibodies thereto, and systems for identifying such antigenic peptides
|
|
EP1357828A2
(en)
|
2001-01-12 |
2003-11-05 |
University of Medicine and Dentistry of New Jersey |
Bone morphogenetic protein-2 in the treatment and diagnosis of cancer
|
|
US20030119119A1
(en)
|
2001-01-16 |
2003-06-26 |
Genentech, Inc. |
Secreted and transmembrane polypeptides and nucleic acids encoding the same
|
|
US20030119126A1
(en)
|
2001-01-16 |
2003-06-26 |
Genentech, Inc. |
Secreted and transmembrane polypeptides and nucleic acids encoding the same
|
|
US7754208B2
(en)
|
2001-01-17 |
2010-07-13 |
Trubion Pharmaceuticals, Inc. |
Binding domain-immunoglobulin fusion proteins
|
|
MXPA03006617A
(es)
|
2001-01-24 |
2004-12-02 |
Protein Design Labs Inc |
Metodos de diagnostico de cancer de pecho, composiciones y metodos de rastreo de moduladores de cancer de pecho.
|
|
AU2002251841A1
(en)
|
2001-01-30 |
2002-08-12 |
Corixa Corporation |
Compositions and methods for the therapy and diagnosis of pancreatic cancer
|
|
WO2002064780A1
(en)
|
2001-02-12 |
2002-08-22 |
Bionomics Limited |
Dna sequences for human tumour suppressor genes
|
|
WO2002071928A2
(en)
|
2001-03-14 |
2002-09-19 |
Millennium Pharmaceuticals, Inc. |
Nucleic acid molecules and proteins for the identification, assessment, prevention, and therapy of ovarian cancer
|
|
EP1243276A1
(en)
|
2001-03-23 |
2002-09-25 |
Franciscus Marinus Hendrikus De Groot |
Elongated and multiple spacers containing activatible prodrugs
|
|
US20040236091A1
(en)
|
2001-03-28 |
2004-11-25 |
Chicz Roman M. |
Translational profiling
|
|
US6362331B1
(en)
|
2001-03-30 |
2002-03-26 |
Council Of Scientific And Industrial Research |
Process for the preparation of antitumor agents
|
|
WO2003008537A2
(en)
|
2001-04-06 |
2003-01-30 |
Mannkind Corporation |
Epitope sequences
|
|
US6820011B2
(en)
|
2001-04-11 |
2004-11-16 |
The Regents Of The University Of Colorado |
Three-dimensional structure of complement receptor type 2 and uses thereof
|
|
CA2443617C
(en)
|
2001-04-17 |
2013-12-10 |
The Board Of Trustees Of The University Of Arkansas |
Repeat sequences of the ca125 gene and their use for diagnostic and therapeutic interventions
|
|
JP2005527180A
(ja)
|
2001-04-18 |
2005-09-15 |
プロテイン デザイン ラブス, インコーポレイテッド |
肺がんの診断方法、肺がんの修飾因子の組成及びスクリーニングの方法
|
|
EA007469B1
(ru)
|
2001-04-26 |
2006-10-27 |
Байоджен Айдек Эмэй Инк. |
Антитела, блокирующие cripto, и их применения
|
|
US6884869B2
(en)
|
2001-04-30 |
2005-04-26 |
Seattle Genetics, Inc. |
Pentapeptide compounds and uses related thereto
|
|
EP1515982A4
(en)
|
2001-05-09 |
2005-10-26 |
Corixa Corp |
COMPOSITIONS AND METHODS FOR THE THERAPY AND DIAGNOSIS OF PROSTATE CANCER
|
|
AU2002344326A1
(en)
|
2001-05-11 |
2002-11-25 |
Sloan-Kettering Institute For Cancer Research |
Nucleic acid sequence encoding ovarian antigen, ca125, and uses thereof
|
|
PL403488A1
(pl)
|
2001-05-24 |
2013-07-08 |
Zymogenetics, Inc. |
Zastosowanie bialka fuzyjnego TACI-immunoglobulina, bialko fuzyjne, czasteczka kwasu nukleinowego kodujaca bialko fuzyjne, kompozycja farmaceutyczna i sposób wytwarzania bialka fuzyjnego TACI-immunoglobulina
|
|
AU2002314901A1
(en)
|
2001-06-04 |
2002-12-16 |
Eos Biotechnology, Inc. |
Methods of diagnosis and treatment of androgen-dependent prostate cancer, prostate cancer undergoing androgen-withdrawal, and androgen-independent prostate cancer
|
|
WO2003000842A2
(en)
|
2001-06-04 |
2003-01-03 |
Curagen Corporation |
Novel proteins and nucleic acids encoding same
|
|
DE60237917D1
(de)
|
2001-06-05 |
2010-11-18 |
Exelixis Inc |
Gfats als modifikatoren des p53-wegs und verwendungsverfahren
|
|
CA2449482A1
(en)
|
2001-06-05 |
2002-12-12 |
Exelixis, Inc. |
Chds as modifiers of the p53 pathway and methods of use
|
|
US7235358B2
(en)
|
2001-06-08 |
2007-06-26 |
Expression Diagnostics, Inc. |
Methods and compositions for diagnosing and monitoring transplant rejection
|
|
US7125663B2
(en)
|
2001-06-13 |
2006-10-24 |
Millenium Pharmaceuticals, Inc. |
Genes, compositions, kits and methods for identification, assessment, prevention, and therapy of cervical cancer
|
|
US7189507B2
(en)
|
2001-06-18 |
2007-03-13 |
Pdl Biopharma, Inc. |
Methods of diagnosis of ovarian cancer, compositions and methods of screening for modulators of ovarian cancer
|
|
EP1517998A2
(en)
|
2001-06-18 |
2005-03-30 |
EOS Biotechnology, Inc. |
Methods of diagnosis of ovarian cancer, compositions and methods of screening for modulators of ovarian cancer
|
|
AU2002322280A1
(en)
|
2001-06-21 |
2003-01-21 |
Millennium Pharmaceuticals, Inc. |
Compositions, kits, and methods for identification, assessment, prevention, and therapy of breast cancer
|
|
WO2003002717A2
(en)
|
2001-06-28 |
2003-01-09 |
Schering Corporation |
Biological activity of ak155
|
|
US20030120040A1
(en)
|
2001-06-29 |
2003-06-26 |
Genentech, Inc. |
Secreted and Transmembrane polypeptides and nucleic acids encoding the same
|
|
WO2003004529A2
(en)
|
2001-07-02 |
2003-01-16 |
Licentia Ltd. |
Ephrin-tie receptor materials and methods
|
|
US20040076955A1
(en)
|
2001-07-03 |
2004-04-22 |
Eos Biotechnology, Inc. |
Methods of diagnosis of bladder cancer, compositions and methods of screening for modulators of bladder cancer
|
|
WO2003003984A2
(en)
|
2001-07-05 |
2003-01-16 |
Curagen Corporation |
Novel proteins and nucleic acids encoding same
|
|
US7446185B2
(en)
|
2001-07-18 |
2008-11-04 |
The Regents Of The University Of California |
Her2/neu target antigen and use of same to stimulate an immune response
|
|
AU2002337657A1
(en)
|
2001-07-25 |
2003-02-17 |
Millennium Pharmaceuticals, Inc. |
Novel genes, compositions, kits, and methods for identification, assessment, prevention, and therapy of prostate cancer
|
|
CA2453995A1
(en)
|
2001-08-03 |
2003-02-20 |
Genentech, Inc. |
Tacis and br3 polypeptides and uses thereof
|
|
CA2457819A1
(en)
|
2001-08-14 |
2003-02-27 |
The General Hospital Corporation |
Nucleic acid and amino acid sequences involved in pain
|
|
US20030092013A1
(en)
|
2001-08-16 |
2003-05-15 |
Vitivity, Inc. |
Diagnosis and treatment of vascular disease
|
|
AU2002313559A1
(en)
|
2001-08-23 |
2003-03-10 |
Oxford Biomedica (Uk) Limited |
Genes
|
|
AU2002357643A1
(en)
|
2001-08-29 |
2003-04-14 |
Vanderbilt University |
The human mob-5 (il-24) receptors and uses thereof
|
|
US20030124579A1
(en)
|
2001-09-05 |
2003-07-03 |
Eos Biotechnology, Inc. |
Methods of diagnosis of ovarian cancer, compositions and methods of screening for modulators of ovarian cancer
|
|
AU2002336446B2
(en)
|
2001-09-06 |
2008-03-06 |
Agensys, Inc. |
Nucleic acid and corresponding protein entitled STEAP-1 useful in treatment and detection of cancer
|
|
CA2459219A1
(en)
|
2001-09-17 |
2003-03-27 |
Protein Design Labs, Inc. |
Methods of diagnosis of cancer compositions and methods of screening for modulators of cancer
|
|
WO2003025228A1
(en)
|
2001-09-18 |
2003-03-27 |
Proteologics, Inc. |
Methods and compositions for treating hcap associated diseases
|
|
EP2153843B1
(en)
|
2001-09-18 |
2012-08-15 |
Genentech, Inc. |
Compositions and methods for the diagnosis and treatment of tumor
|
|
CA2460621A1
(en)
|
2001-09-19 |
2003-03-27 |
Nuvelo, Inc. |
Novel nucleic acids and polypeptides
|
|
WO2003026577A2
(en)
|
2001-09-24 |
2003-04-03 |
Seattle Genetics, Inc. |
P-amidobenzylethers in drug delivery agents
|
|
US7091186B2
(en)
|
2001-09-24 |
2006-08-15 |
Seattle Genetics, Inc. |
p-Amidobenzylethers in drug delivery agents
|
|
WO2003026493A2
(en)
|
2001-09-28 |
2003-04-03 |
Bing Yang |
Diagnosis and treatment of diseases caused by mutations in cd72
|
|
US20050130117A1
(en)
|
2001-10-03 |
2005-06-16 |
Davis Cong L. |
Modulators of lymphocyte activation and migration
|
|
AU2002362454A1
(en)
|
2001-10-03 |
2003-04-14 |
Origene Technologies, Inc. |
Regulated breast cancer genes
|
|
CA2461665A1
(en)
|
2001-10-19 |
2003-05-01 |
Genentech, Inc. |
Compositions and methods for the diagnosis and treatment of inflammatory bowel disorders
|
|
US20050123925A1
(en)
|
2002-11-15 |
2005-06-09 |
Genentech, Inc. |
Compositions and methods for the diagnosis and treatment of tumor
|
|
WO2004016225A2
(en)
|
2002-08-19 |
2004-02-26 |
Genentech, Inc. |
Compositions and methods for the diagnosis and treatment of tumor
|
|
WO2003035846A2
(en)
|
2001-10-24 |
2003-05-01 |
National Jewish Medical And Research Center |
Structure of tall-1 and its cognate receptor
|
|
MXPA04003697A
(es)
|
2001-10-31 |
2005-04-08 |
Alcon Inc |
Proteinas morfogenicas de hueso (bmp), receptores de bmp y proteinas de enlace de bmp y su uso en el diagnostico y tratamiento de glaucoma.
|
|
WO2003042661A2
(en)
|
2001-11-13 |
2003-05-22 |
Protein Design Labs, Inc. |
Methods of diagnosis of cancer, compositions and methods of screening for modulators of cancer
|
|
US20030232350A1
(en)
|
2001-11-13 |
2003-12-18 |
Eos Biotechnology, Inc. |
Methods of diagnosis of cancer, compositions and methods of screening for modulators of cancer
|
|
WO2003043583A2
(en)
|
2001-11-20 |
2003-05-30 |
Seattle Genetics, Inc. |
Treatment of immunological disorders using anti-cd30 antibodies
|
|
EP1448226A1
(en)
|
2001-11-29 |
2004-08-25 |
Genset S.A. |
Agonists and antagonists of prolixin for the treatment of metabolic disorders
|
|
WO2003048202A2
(en)
|
2001-12-03 |
2003-06-12 |
Asahi Kasei Pharma Corporation |
Nf-kappab activating genes
|
|
PT1461428E
(pt)
|
2001-12-03 |
2012-05-29 |
Alexion Pharma Inc |
Método para produção de anticorpos híbridos
|
|
AU2002366951A1
(en)
|
2001-12-10 |
2003-07-09 |
Nuvelo,Inc. |
Novel nucleic acids and polypeptides
|
|
US20030134790A1
(en)
|
2002-01-11 |
2003-07-17 |
University Of Medicine And Dentistry Of New Jersey |
Bone Morphogenetic Protein-2 And Bone Morphogenetic Protein-4 In The Treatment And Diagnosis Of Cancer
|
|
JP4133832B2
(ja)
|
2002-01-16 |
2008-08-13 |
独立行政法人科学技術振興機構 |
カラー動画ホログラフィ再生装置
|
|
US7452675B2
(en)
|
2002-01-25 |
2008-11-18 |
The Queen's Medical Center |
Methods of screening for TRPM4b modulators
|
|
JP2005526044A
(ja)
|
2002-02-21 |
2005-09-02 |
デューク ユニバーシティ |
抗cd22抗体を使用した治療方法
|
|
CA2476518A1
(en)
|
2002-02-22 |
2003-09-04 |
Genentech, Inc. |
Compositions and methods for the treatment of immune related diseases
|
|
AU2003216482A1
(en)
|
2002-03-01 |
2003-09-16 |
Exelixis, Inc. |
MSRAs AS MODIFIERS OF THE p53 PATHWAY AND METHODS OF USE
|
|
WO2003097803A2
(en)
|
2002-05-15 |
2003-11-27 |
Avalon Pharmaceuticals |
Cancer-linked gene as target for chemotherapy
|
|
US6660856B2
(en)
|
2002-03-08 |
2003-12-09 |
Kaohsiung Medical University |
Synthesis of pyrrolo[2,1-c][1,4]benzodiazepine analogues
|
|
EP2258712A3
(en)
|
2002-03-15 |
2011-05-04 |
Multicell Immunotherapeutics, Inc. |
Compositions and Methods to Initiate or Enhance Antibody and Major-histocompatibility Class I or Class II-restricted T Cell Responses by Using Immunomodulatory, Non-coding RNA Motifs
|
|
CA2486490A1
(en)
|
2002-03-19 |
2003-12-31 |
Curagen Corporation |
Therapeutic polypeptides, nucleic acids encoding same, and methods of use
|
|
JP2005534286A
(ja)
|
2002-03-21 |
2005-11-17 |
サネシス ファーマシューティカルズ, インコーポレイテッド |
キナーゼインヒビターの同定
|
|
US7193069B2
(en)
|
2002-03-22 |
2007-03-20 |
Research Association For Biotechnology |
Full-length cDNA
|
|
EP1494693B1
(en)
|
2002-03-22 |
2010-12-08 |
Biogen Idec MA Inc. |
Cripto-specific antibodies
|
|
US7317087B2
(en)
|
2002-03-25 |
2008-01-08 |
The Uab Research Foundation |
Members of the FC receptor homolog gene family (FCRH1-3, 6), related reagents, and uses thereof
|
|
AU2003222103A1
(en)
|
2002-03-28 |
2003-10-13 |
Idec Pharmaceuticals Corporation |
Novel gene targets and ligands that bind thereto for treatment and diagnosis of colon carcinomas
|
|
US20030194704A1
(en)
|
2002-04-03 |
2003-10-16 |
Penn Sharron Gaynor |
Human genome-derived single exon nucleic acid probes useful for gene expression analysis two
|
|
EP1572916A4
(en)
|
2002-04-05 |
2007-05-30 |
Agensys Inc |
NUCLEIC ACID AND CORRESPONDING PROTEIN WITH THE NAME 98P4B6, SUITABLE FOR THE TREATMENT AND DETECTION OF CANCER
|
|
US20040101874A1
(en)
|
2002-04-12 |
2004-05-27 |
Mitokor Inc. |
Targets for therapeutic intervention identified in the mitochondrial proteome
|
|
MXPA04010092A
(es)
|
2002-04-16 |
2004-12-13 |
Genentech Inc |
Composiciones y metodos para el diagnostico y tratamiento de tumores.
|
|
WO2003089904A2
(en)
|
2002-04-17 |
2003-10-30 |
Baylor College Of Medicine |
Aib1 as a prognostic marker and predictor of resistance to encocrine therapy
|
|
AU2003228869A1
(en)
|
2002-05-03 |
2003-11-17 |
Incyte Corporation |
Transporters and ion channels
|
|
AU2003232453A1
(en)
|
2002-05-30 |
2003-12-19 |
David K. Bol |
Human solute carrier family 7 member 11 (hslc7a11)
|
|
WO2003101283A2
(en)
|
2002-06-04 |
2003-12-11 |
Incyte Corporation |
Diagnostics markers for lung cancer
|
|
AU2003239969A1
(en)
|
2002-06-04 |
2003-12-19 |
Avalon Pharmaceuticals, Inc. |
Cancer-linked gene as target for chemotherapy
|
|
AU2003242633A1
(en)
|
2002-06-06 |
2003-12-22 |
Molecular Engines Laboratories |
Dudulin genes, non-human animal model: uses in human hematological disease
|
|
CA2488404C
(en)
|
2002-06-06 |
2012-11-27 |
Oncotherapy Science, Inc. |
Genes and polypeptides relating to human colon cancers
|
|
CA2488629A1
(en)
|
2002-06-07 |
2003-12-18 |
Avalon Pharmaceuticals, Inc |
Cancer-linked gene as target for chemotherapy
|
|
WO2003105758A2
(en)
|
2002-06-12 |
2003-12-24 |
Avalon Pharmaceuticals, Inc. |
Cancer-linked gene as target for chemotherapy
|
|
EP1552002A4
(en)
|
2002-06-18 |
2006-02-08 |
Archemix Corp |
APTAMER TOXIN MOLECULES AND METHOD FOR THEIR USE
|
|
US20040249130A1
(en)
|
2002-06-18 |
2004-12-09 |
Martin Stanton |
Aptamer-toxin molecules and methods for using same
|
|
EP1539218A4
(en)
|
2002-06-20 |
2007-08-22 |
Univ California |
COMPOSITIONS AND METHODS FOR MODULATING LYMPHOCYTE ACTIVITY
|
|
AU2003278161A1
(en)
|
2002-06-21 |
2004-01-06 |
Johns Hopkins University School Of Medicine |
Membrane associated tumor endothelium markers
|
|
DE10229834A1
(de)
|
2002-07-03 |
2004-01-29 |
Zinser Textilmaschinen Gmbh |
Streckwerk für Spinnmaschinen mit nachgeordneter Verdichtungsvorrichtung
|
|
WO2004009622A2
(en)
|
2002-07-19 |
2004-01-29 |
Cellzome Ag |
Protein complexes of cellular networks underlying the development of cancer and other diseases
|
|
BR0313033A
(pt)
|
2002-07-25 |
2007-07-10 |
Genentech Inc |
anticorpos, anticorpos monoclonais, linhagens de células de hibridoma, anticorpos receptores de anti-taci isolados, anticorpos anti -taci, métodos de modulação da atividade biológica
|
|
SI1545613T1
(sl)
|
2002-07-31 |
2011-11-30 |
Seattle Genetics Inc |
Avristatinski konjugati in njihova uporaba za zdravljenje raka avtoimunske bolezni ali infekcijskebolezni
|
|
US20050180972A1
(en)
|
2002-07-31 |
2005-08-18 |
Wahl Alan F. |
Anti-CD20 antibody-drug conjugates for the treatment of cancer and immune disorders
|
|
JP2004121218A
(ja)
|
2002-08-06 |
2004-04-22 |
Jenokkusu Soyaku Kenkyusho:Kk |
気管支喘息または慢性閉塞性肺疾患の検査方法
|
|
WO2004015426A1
(en)
|
2002-08-06 |
2004-02-19 |
Bayer Healthcare Ag |
Diagnostics and therapeutics for diseases associated with human cxc chemokine receptor 5(cxcr5)
|
|
AU2003278725A1
(en)
|
2002-08-27 |
2004-03-19 |
Bristol-Myers Squibb Company |
Polynucleotide predictor set for identifying protein tyrosine kinase modulators
|
|
WO2004020595A2
(en)
|
2002-08-29 |
2004-03-11 |
Five Prime Therapeutics, Inc. |
Novel human polypeptides encoded by polynucleotides
|
|
WO2004019993A1
(en)
|
2002-08-30 |
2004-03-11 |
Ramot At Tel Aviv University Ltd. |
Self-immolative dendrimers releasing many active moieties upon a single activating event
|
|
AU2002951346A0
(en)
|
2002-09-05 |
2002-09-26 |
Garvan Institute Of Medical Research |
Diagnosis of ovarian cancer
|
|
AU2003270311A1
(en)
|
2002-09-06 |
2004-03-29 |
Mannkind Corporation |
Epitope sequences
|
|
AU2003300776A1
(en)
|
2002-09-09 |
2004-05-25 |
Omeros Corporation |
G protein coupled receptors and uses thereof
|
|
JP2004113151A
(ja)
|
2002-09-27 |
2004-04-15 |
Sankyo Co Ltd |
癌遺伝子及びその用途
|
|
AU2003288918A1
(en)
|
2002-10-04 |
2004-05-04 |
Van Andel Research Institute |
Molecular sub-classification of kidney tumors and the discovery of new diagnostic markers
|
|
US20040138269A1
(en)
|
2002-10-11 |
2004-07-15 |
Sugen, Inc. |
Substituted pyrroles as kinase inhibitors
|
|
CA2503748A1
(en)
|
2002-11-08 |
2004-05-27 |
Genentech, Inc. |
Compositions and methods for the treatment of natural killer cell related diseases
|
|
US20040146907A1
(en)
|
2002-11-13 |
2004-07-29 |
Genentech, Inc. |
Methods and compositions for detecting dysplasia
|
|
WO2004043493A1
(en)
|
2002-11-14 |
2004-05-27 |
Syntarga B.V. |
Prodrugs built as multiple self-elimination-release spacers
|
|
GB0226593D0
(en)
|
2002-11-14 |
2002-12-24 |
Consultants Ltd |
Compounds
|
|
BRPI0316282B8
(pt)
*
|
2002-11-15 |
2021-05-25 |
Genmab As |
anticorpo humano isolado monoclonal, composição, imunoconjugado, molécula biespecífica ou multiespecífica, método e conjunto de diagnóstico para detectar a presença de antígeno cd25 ou uma célula que expressa cd25, e, vetor de expressão
|
|
AU2003294355A1
(en)
|
2002-11-15 |
2004-06-15 |
The Board Of Trustees Of The University Of Arkansas |
Ca125 gene and its use for diagnostic and therapeutic interventions
|
|
EP1569685B8
(en)
|
2002-11-15 |
2012-12-05 |
MUSC Foundation For Research Development |
Complement receptor 2 targeted complement modulators
|
|
US20080213166A1
(en)
|
2002-11-20 |
2008-09-04 |
Biogen Idec Inc. |
Novel Gene Targets and Ligands that Bind Thereto for Treatment and Diagnosis of Colon Carcinomas
|
|
AU2003294462C1
(en)
|
2002-11-21 |
2011-06-30 |
University Of Utah Research Foundation |
Purinergic modulation of smell
|
|
AU2003298786A1
(en)
|
2002-11-26 |
2004-06-18 |
Protein Design Labs, Inc. |
Methods of detecting soft tissue sarcoma, compositions and methods of screening for soft tissue sarcoma modulators
|
|
AU2003302774A1
(en)
|
2002-12-06 |
2004-06-30 |
Diadexus, Inc. |
Compositions, splice variants and methods relating to ovarian specific genes and proteins
|
|
JP2004198419A
(ja)
|
2002-12-13 |
2004-07-15 |
Bayer Healthcare Llc |
Timp1を用いた検出方法
|
|
JP4898120B2
(ja)
|
2002-12-20 |
2012-03-14 |
アボット バイオセラピューティクス コーポレイション |
Gpr64に対する抗体とその利用法
|
|
AU2003299819A1
(en)
|
2002-12-23 |
2004-07-22 |
Human Genome Sciences, Inc. |
Neutrokine-alpha conjugate, neutrokine-alpha complex, and uses thereof
|
|
EP1597558A2
(en)
|
2003-01-08 |
2005-11-23 |
Bristol-Myers Squibb Company |
Biomarkers and methods for determining sensitivity to epidermal growth factor receptor modulators
|
|
US20050227301A1
(en)
|
2003-01-10 |
2005-10-13 |
Polgen |
Cell cycle progression proteins
|
|
WO2004063355A2
(en)
|
2003-01-10 |
2004-07-29 |
Protein Design Labs, Inc. |
Novel methods of diagnosis of metastatic cancer, compositions and methods of screening for modulators of matastatic cancer
|
|
US20040171823A1
(en)
|
2003-01-14 |
2004-09-02 |
Nadler Steven G. |
Polynucleotides and polypeptides associated with the NF-kappaB pathway
|
|
US7258971B2
(en)
|
2003-01-15 |
2007-08-21 |
Bayer Healthcare Ag |
Methods and compositions for treating urological disorders using carboxypeptidase Z identified as 8263
|
|
AU2004213432A1
(en)
|
2003-02-14 |
2004-09-02 |
Sagres Discovery, Inc. |
Novel therapeutic targets in cancer
|
|
US20030224411A1
(en)
|
2003-03-13 |
2003-12-04 |
Stanton Lawrence W. |
Genes that are up- or down-regulated during differentiation of human embryonic stem cells
|
|
US6884799B2
(en)
|
2003-03-31 |
2005-04-26 |
Council Of Scientific And Industrial Research |
Non-cross-linking pyrrolo[2,1-c][1,4]benzodiazepines and process thereof
|
|
GB0321295D0
(en)
|
2003-09-11 |
2003-10-15 |
Spirogen Ltd |
Synthesis of protected pyrrolobenzodiazepines
|
|
GB0416511D0
(en)
|
2003-10-22 |
2004-08-25 |
Spirogen Ltd |
Pyrrolobenzodiazepines
|
|
US7511032B2
(en)
|
2003-10-22 |
2009-03-31 |
The United States Of America As Represented By The Secretary, Department Of Health And Human Services |
Pyrrolobenzodiazepine derivatives, compositions comprising the same and methods related thereto
|
|
DK1725249T3
(en)
|
2003-11-06 |
2014-03-17 |
Seattle Genetics Inc |
Monomethylvaline compounds capable of conjugating to ligands.
|
|
EP1720908A2
(en)
|
2004-02-17 |
2006-11-15 |
Absalus, Inc. |
Super-humanized antibodies against respiratory syncytial virus
|
|
JP5064037B2
(ja)
|
2004-02-23 |
2012-10-31 |
ジェネンテック, インコーポレイテッド |
複素環式自壊的リンカーおよび結合体
|
|
GB0404578D0
(en)
|
2004-03-01 |
2004-04-07 |
Spirogen Ltd |
Pyrrolobenzodiazepines
|
|
GB0404577D0
(en)
|
2004-03-01 |
2004-04-07 |
Spirogen Ltd |
Pyrrolobenzodiazepines
|
|
GB0404574D0
(en)
|
2004-03-01 |
2004-04-07 |
Spirogen Ltd |
Amino acids
|
|
SI2270010T1
(sl)
|
2004-03-01 |
2012-05-31 |
Spirogen Ltd |
hidroksi H pirolo c benzodiazepin onski derivati kot ključni intermediati za pripravo C substituiranih pirolobenzodiazepinov
|
|
DE102004010943A1
(de)
|
2004-03-03 |
2005-09-29 |
Degussa Ag |
Verfahren zur Herstellung von N-geschützten 4-Ketprolinderivaten
|
|
WO2005085260A1
(en)
|
2004-03-09 |
2005-09-15 |
Spirogen Limited |
Pyrrolobenzodiazepines
|
|
FR2869231B1
(fr)
|
2004-04-27 |
2008-03-14 |
Sod Conseils Rech Applic |
Composition therapeutique contenant au moins un derive de la pyrrolobenzodiazepine et la fludarabine
|
|
GB0410725D0
(en)
|
2004-05-13 |
2004-06-16 |
Spirogen Ltd |
Pyrrolobenzodiazepine therapeutic agents
|
|
ES2579805T3
(es)
|
2004-09-23 |
2016-08-16 |
Genentech, Inc. |
Anticuerpos y conjugados modificados por ingeniería genética con cisteína
|
|
EP1831418A2
(en)
|
2004-12-24 |
2007-09-12 |
Showa Denko Kabushiki Kaisha |
Production method of thermoelectric semiconductor alloy, thermoelectric conversion module and thermoelectric power generating device
|
|
DK1844074T3
(da)
|
2005-02-03 |
2013-07-15 |
Antitope Ltd |
Humane antistoffer og proteiner
|
|
AU2006236225C1
(en)
|
2005-04-19 |
2013-05-02 |
Seagen Inc. |
Humanized anti-CD70 binding agents and uses thereof
|
|
PL1879901T3
(pl)
|
2005-04-21 |
2010-06-30 |
Medimmune Ltd |
Pirolobenzodiazepiny
|
|
DE602006006199D1
(de)
|
2005-10-05 |
2009-05-20 |
Spirogen Ltd |
4-ä4-(5-oxo-2,3,5,11a-tetrahydro-5h-pyrrolo ä2, 1-cüä1,4übenzodiazepin-8-yloxy)-butyrylaminoü-1h-pyrrol-2-carbonsäurealkylesterderivate und verwandte verbindung zur behandlung einer proliferativen erkrankung
|
|
SI1934174T1
(sl)
|
2005-10-07 |
2011-08-31 |
Exelixis Inc |
Inhibitorji MEK in postopki za njihovo uporabo
|
|
DK2270050T3
(da)
|
2005-12-30 |
2013-08-12 |
Merck Patent Gmbh |
Anti-CD19-antistoffer med nedsat immunogenicitet
|
|
SI1813614T1
(sl)
|
2006-01-25 |
2012-01-31 |
Sanofi 174 |
Citotoksična sredstva, ki obsegajo nove tomajmicinske derivate
|
|
NZ574215A
(en)
|
2006-07-18 |
2012-07-27 |
Sanofi Aventis |
Antagonist antibody against epha2 for the treatment of cancer
|
|
DK2059536T3
(da)
|
2006-08-14 |
2014-04-14 |
Xencor Inc |
Optimerede antistoffer, der er rettet mod cd19
|
|
US20080112961A1
(en)
|
2006-10-09 |
2008-05-15 |
Macrogenics, Inc. |
Identification and Engineering of Antibodies with Variant Fc Regions and Methods of Using Same
|
|
EP1914242A1
(en)
|
2006-10-19 |
2008-04-23 |
Sanofi-Aventis |
Novel anti-CD38 antibodies for the treatment of cancer
|
|
ES2523915T5
(es)
|
2006-12-01 |
2022-05-26 |
Seagen Inc |
Agentes de unión a la diana variantes y usos de los mismos
|
|
JP2010516651A
(ja)
*
|
2007-01-17 |
2010-05-20 |
メルク セローノ ソシエテ アノニム |
Fc含有タンパク質の精製のための方法
|
|
CL2008001334A1
(es)
|
2007-05-08 |
2008-09-22 |
Genentech Inc |
Anticuerpo anti-muc16 disenado con cisteina; conjugado que lo comprende; metodo de produccion; formulacion farmaceutica que lo comprende; y su uso para tratar el cancer.
|
|
EP2019104B1
(en)
|
2007-07-19 |
2013-09-04 |
Sanofi |
Cytotoxic agents comprising new tomaymycin derivatives and their therapeutic use
|
|
US8937161B2
(en)
|
2007-10-19 |
2015-01-20 |
Genentech, Inc. |
Cysteine engineered anti-TENB2 antibodies and antibody drug conjugates
|
|
PL2265283T3
(pl)
|
2008-03-18 |
2015-03-31 |
Seattle Genetics Inc |
Koniugaty aurystatyny lek łącznik
|
|
GB0813432D0
(en)
|
2008-07-22 |
2008-08-27 |
Spirogen Ltd |
Pyrrolobenzodiazepines
|
|
KR101631610B1
(ko)
|
2008-10-15 |
2016-06-17 |
짐머 게엠베하 |
골수내 못
|
|
GB0819097D0
(en)
|
2008-10-17 |
2008-11-26 |
Spirogen Ltd |
Pyrrolobenzodiazepines
|
|
GB0819095D0
(en)
*
|
2008-10-17 |
2008-11-26 |
Spirogen Ltd |
Pyrrolobenzodiazepines
|
|
JP5977522B2
(ja)
|
2009-02-05 |
2016-08-24 |
イミュノジェン・インコーポレーテッド |
新規ベンゾジアゼピン誘導体
|
|
CA2753158A1
(en)
|
2009-02-23 |
2010-08-26 |
Glenmark Pharmaceuticals S.A. |
Humanized antibodies that bind to cd19 and their uses
|
|
FR2949469A1
(fr)
|
2009-08-25 |
2011-03-04 |
Sanofi Aventis |
Derives anticancereux, leur preparation et leur application en therapeutique
|
|
CN102612524A
(zh)
|
2009-09-01 |
2012-07-25 |
雅培制药有限公司 |
双重可变结构域免疫球蛋白及其用途
|
|
WO2011038159A2
(en)
|
2009-09-24 |
2011-03-31 |
Seattle Genetics, Inc. |
Dr5 ligand drug conjugates
|
|
US9040526B2
(en)
|
2010-02-09 |
2015-05-26 |
Bristol-Myers Squibb Company |
Benzylpyrrolidinone derivatives as modulators of chemokine receptor activity
|
|
WO2011130615A2
(en)
|
2010-04-15 |
2011-10-20 |
Dr. Reddy's Laboratories Ltd. |
Preparation of lacosamide
|
|
RS52983B
(sr)
|
2010-04-15 |
2014-02-28 |
Spirogen Sárl |
Pirolobenzodiazepini i njihovi konjugati
|
|
JP5875083B2
(ja)
*
|
2010-04-15 |
2016-03-02 |
メディミューン リミテッド |
増殖性疾患治療用ピロロベンゾジアゼピン
|
|
EP2558127B1
(en)
|
2010-04-15 |
2022-01-19 |
Seagen Inc. |
Targeted pyrrolobenzodiazepine conjugates
|
|
GB201006340D0
(en)
|
2010-04-15 |
2010-06-02 |
Spirogen Ltd |
Synthesis method and intermediates
|
|
TWI617555B
(zh)
|
2011-02-15 |
2018-03-11 |
免疫原公司 |
細胞毒性苯并二氮呯衍生物
|
|
KR101860174B1
(ko)
|
2011-09-20 |
2018-05-21 |
메디뮨 리미티드 |
표적 접합체 내의 내포를 위한 비대칭 이량체 pbd 화합물로서 피롤로벤조디아제핀
|
|
HUE025661T2
(en)
|
2011-10-14 |
2016-04-28 |
Medimmune Ltd |
Pyrrolobenzodiazepines and their conjugates
|
|
CN104011018B
(zh)
|
2011-10-14 |
2016-12-14 |
麦迪穆有限责任公司 |
可用于制备吡咯并苯并二氮杂卓的合成方法和中间体
|
|
ES2945932T3
(es)
|
2011-10-14 |
2023-07-10 |
Seagen Inc |
Pirrolobenzodiazepinas y conjugados dirigidos
|
|
EP2751111B1
(en)
|
2011-10-14 |
2017-04-26 |
MedImmune Limited |
Asymmetrical bis-(5H-Pyrrolo[2,1-c][1,4]benzodiazepin-5-one) derivatives for the treatment of proliferative or autoimmune diseases
|
|
US9387259B2
(en)
|
2011-10-14 |
2016-07-12 |
Seattle Genetics, Inc. |
Pyrrolobenzodiazepines and targeted conjugates
|
|
EA027386B1
(ru)
|
2011-10-14 |
2017-07-31 |
Медимьюн Лимитед |
Пирролобензодиазепины
|
|
JP2015523380A
(ja)
|
2012-07-09 |
2015-08-13 |
ジェネンテック, インコーポレイテッド |
抗cd79b抗体を含む免疫複合体
|
|
EP2869849A1
(en)
|
2012-07-09 |
2015-05-13 |
Genentech, Inc. |
Immunoconjugates comprising anti-cd22 antibodies
|
|
EP2879708A4
(en)
|
2012-08-02 |
2016-03-16 |
Genentech Inc |
ANTIBODY AND ANTI-ETBR IMMUNOCONJUGATES
|
|
JP6367204B2
(ja)
|
2012-10-12 |
2018-08-01 |
メドイミューン・リミテッドMedImmune Limited |
結合用のピロロベンゾジアゼピン誘導体の合成および中間体
|
|
SI2766048T1
(sl)
|
2012-10-12 |
2015-03-31 |
Spirogen Sarl |
Pirolobenzodiazepini in njihovi konjugati
|
|
TR201808051T4
(tr)
*
|
2012-10-12 |
2018-06-21 |
Adc Therapeutics Sa |
Pirrolobenzodiazepin antikor konjugatları.
|
|
LT2906248T
(lt)
|
2012-10-12 |
2019-02-11 |
Medimmune Limited |
Pirolobenzodiazepinai ir jų konjugatai
|
|
MX363787B
(es)
|
2013-03-13 |
2019-04-03 |
Medimmune Ltd |
Pirrolobenzodiazepinas y conjugados de los mismos.
|
|
CN107148285B
(zh)
*
|
2014-11-25 |
2022-01-04 |
Adc治疗股份有限公司 |
吡咯并苯并二氮杂䓬-抗体缀合物
|
|
BR112019021680A2
(pt)
*
|
2017-04-20 |
2020-05-12 |
Adc Therapeutics Sa |
Terapia de combinação com conjugado anticorpo-fármaco anti-cd25??
|