CY1113504T1 - Παραγωγο προπανο-1,3-διονης ή αλας αυτου - Google Patents
Παραγωγο προπανο-1,3-διονης ή αλας αυτουInfo
- Publication number
- CY1113504T1 CY1113504T1 CY20121101266T CY121101266T CY1113504T1 CY 1113504 T1 CY1113504 T1 CY 1113504T1 CY 20121101266 T CY20121101266 T CY 20121101266T CY 121101266 T CY121101266 T CY 121101266T CY 1113504 T1 CY1113504 T1 CY 1113504T1
- Authority
- CY
- Cyprus
- Prior art keywords
- compound
- present
- gnrh receptor
- propane
- gnrh
- Prior art date
Links
- 150000003839 salts Chemical class 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 4
- 102000008238 LHRH Receptors Human genes 0.000 abstract 3
- 108010021290 LHRH Receptors Proteins 0.000 abstract 3
- 201000010099 disease Diseases 0.000 abstract 3
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 3
- WSMYVTOQOOLQHP-UHFFFAOYSA-N Malondialdehyde Chemical class O=CCC=O WSMYVTOQOOLQHP-UHFFFAOYSA-N 0.000 abstract 2
- 230000003042 antagnostic effect Effects 0.000 abstract 2
- 206010013710 Drug interaction Diseases 0.000 abstract 1
- NMJREATYWWNIKX-UHFFFAOYSA-N GnRH Chemical compound C1CCC(C(=O)NCC(N)=O)N1C(=O)C(CC(C)C)NC(=O)C(CC=1C2=CC=CC=C2NC=1)NC(=O)CNC(=O)C(NC(=O)C(CO)NC(=O)C(CC=1C2=CC=CC=C2NC=1)NC(=O)C(CC=1NC=NC=1)NC(=O)C1NC(=O)CC1)CC1=CC=C(O)C=C1 NMJREATYWWNIKX-UHFFFAOYSA-N 0.000 abstract 1
- 101000857870 Squalus acanthias Gonadoliberin Proteins 0.000 abstract 1
- YTPLMLYBLZKORZ-UHFFFAOYSA-N Thiophene Chemical group C=1C=CSC=1 YTPLMLYBLZKORZ-UHFFFAOYSA-N 0.000 abstract 1
- MXMZCLLIUQEKSN-UHFFFAOYSA-N benzimidazoline Chemical compound C1=CC=C2NCNC2=C1 MXMZCLLIUQEKSN-UHFFFAOYSA-N 0.000 abstract 1
- 230000001419 dependent effect Effects 0.000 abstract 1
- 239000003163 gonadal steroid hormone Substances 0.000 abstract 1
- 229940126601 medicinal product Drugs 0.000 abstract 1
- 230000002503 metabolic effect Effects 0.000 abstract 1
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
- 230000003389 potentiating effect Effects 0.000 abstract 1
- 239000002464 receptor antagonist Substances 0.000 abstract 1
- 229940044551 receptor antagonist Drugs 0.000 abstract 1
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
- C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
- C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
- C07D235/06—Benzimidazoles; Hydrogenated benzimidazoles with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 2
- C07D235/12—Radicals substituted by oxygen atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4164—1,3-Diazoles
- A61K31/4184—1,3-Diazoles condensed with carbocyclic rings, e.g. benzimidazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4192—1,2,3-Triazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4196—1,2,4-Triazoles
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/08—Drugs for disorders of the urinary system of the prostate
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
- A61P5/32—Antioestrogens
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/06—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
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- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
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- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/10—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing aromatic rings
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- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
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- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
Abstract
Στοχεύεται η παροχή μίας ενώσεως χρήσιμης ως ανταγωνιστής υποδοχέα GnRH. Οι εφευρέτες διερεύνησαν περαιτέρω τα παράγωγα της προπανο-1,3-διόνης. Ως αποτέλεσμα, επιβεβαίωσαν ότι μία ένωση έχουσα ένα δακτύλιο βενζολίου ή ένα δακτύλιο θειοφαινίου υποκατασταθέντα από μία ομάδα που αναπαριστάται από -SΟ2-R3 σε ένα παράγωγο προπανο-1,3-διόνης που έχει 2-(1,3-διυδρο-2Η-βενζιμιδαζολ-2-υλιδένιο) έχει άριστη ανταγωνιστική δράση υποδοχέα GnRH και πραγματοποίησαν την παρούσα εφεύρεση. Λόγω του ότι η ένωση της παρούσας εφευρέσεως έχει ισχυρή ανταγωνιστική δράση υποδοχέα GnRH, είναι χρήσιμη για την αγωγή νόσων εξαρτώμενων από φυλετικές ορμόνες, συγκεκριμένα νόσων σχετιζόμενων με τη GnRH. Επιπλέον, λόγω του ότι η ένωση της παρούσας εφευρέσεως έχει άριστη μεταβολική σταθερότητα στους ανθρώπους και λίγες αλληλεπιδράσεις με φάρμακα, έχει κατά συνέπεια προτιμώμενα χαρακτηριστικά ως φαρμακευτικό προϊόν χρησιμοποιούμενο για τις προαναφερθείσες νόσους.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2005101437 | 2005-03-31 | ||
JP2005353577 | 2005-12-07 | ||
EP06730589A EP1864976B1 (en) | 2005-03-31 | 2006-03-30 | Propane-1,3-dion derivative or salt thereof |
Publications (1)
Publication Number | Publication Date |
---|---|
CY1113504T1 true CY1113504T1 (el) | 2016-06-22 |
Family
ID=37073368
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CY20121101266T CY1113504T1 (el) | 2005-03-31 | 2012-12-27 | Παραγωγο προπανο-1,3-διονης ή αλας αυτου |
Country Status (20)
Country | Link |
---|---|
US (1) | US7960562B2 (el) |
EP (1) | EP1864976B1 (el) |
JP (1) | JP4715845B2 (el) |
KR (1) | KR101046039B1 (el) |
AU (1) | AU2006232469B2 (el) |
BR (1) | BRPI0609625A2 (el) |
CA (1) | CA2603185C (el) |
CY (1) | CY1113504T1 (el) |
DK (1) | DK1864976T3 (el) |
ES (1) | ES2392859T3 (el) |
HK (1) | HK1109152A1 (el) |
IL (1) | IL185926A (el) |
NO (1) | NO341019B1 (el) |
NZ (1) | NZ561387A (el) |
PL (1) | PL1864976T3 (el) |
PT (1) | PT1864976E (el) |
RU (1) | RU2404973C2 (el) |
SI (1) | SI1864976T1 (el) |
TW (1) | TW200722420A (el) |
WO (1) | WO2006106812A1 (el) |
Families Citing this family (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP2095818A1 (en) * | 2008-02-29 | 2009-09-02 | AEterna Zentaris GmbH | Use of LHRH antagonists at non-castrating doses |
CA2807419C (en) | 2010-08-18 | 2019-09-24 | Sunil Kumar Kc | Diketones and hydroxyketones as catenin signaling pathway activators |
WO2013132253A1 (en) | 2012-03-07 | 2013-09-12 | Institute Of Cancer Research: Royal Cancer Hospital (The) | 3-aryl-5-substituted-isoquinolin-1-one compounds and their therapeutic use |
JP6183053B2 (ja) * | 2012-08-22 | 2017-08-23 | 宇部興産株式会社 | テトラヒドロピラニルピリミジン化合物の製造方法 |
MX351307B (es) * | 2012-09-07 | 2017-10-10 | Astellas Pharma Inc | Método para producir el compuesto sulfonilamidina. |
SI2968249T1 (sl) | 2013-02-22 | 2019-04-30 | Samumed, Llc | Gama-diketoni kot aktivatorji signalne poti Wnt/beta-katenin |
PL231063B1 (pl) * | 2013-04-10 | 2019-01-31 | Oncoarendi Therapeutics Spolka Z Ograniczona Odpowiedzialnoscia | Pochodne 1-(podstawionej sulfonylo)-2-aminoimidazoliny jako środki przeciwnowotworowe |
CN105722835B (zh) | 2013-09-11 | 2018-07-31 | 癌症研究协会:皇家癌症医院 | 3-芳基-5-取代的-异喹啉-1-酮化合物及它们的疗法应用 |
TW201613579A (en) | 2014-06-24 | 2016-04-16 | Astellas Pharma Inc | Pharmaceutical composition for oral administration |
CN107106549B (zh) | 2014-08-20 | 2020-06-16 | 萨穆梅德有限公司 | 用于治疗和预防老化皮肤和皱纹的γ–二酮 |
CA3066190A1 (en) | 2017-06-05 | 2018-12-13 | ObsEva S.A. | Gonadotropin-releasing hormone antagonist dosing regimens for the treatment of endometriosis |
CN111066191B (zh) * | 2017-08-08 | 2023-05-05 | 住友精化株式会社 | 非水电解液用添加剂、非水电解液及蓄电装置 |
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NZ197714A (en) * | 1980-07-15 | 1984-11-09 | Glaxo Group Ltd | Substituted pyrimidin-2-ones and pharmaceutical compositions |
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-
2006
- 2006-03-30 KR KR1020077025090A patent/KR101046039B1/ko active IP Right Grant
- 2006-03-30 ES ES06730589T patent/ES2392859T3/es active Active
- 2006-03-30 JP JP2007512842A patent/JP4715845B2/ja active Active
- 2006-03-30 EP EP06730589A patent/EP1864976B1/en active Active
- 2006-03-30 PL PL06730589T patent/PL1864976T3/pl unknown
- 2006-03-30 US US11/887,384 patent/US7960562B2/en not_active Expired - Fee Related
- 2006-03-30 WO PCT/JP2006/306641 patent/WO2006106812A1/ja active Application Filing
- 2006-03-30 AU AU2006232469A patent/AU2006232469B2/en not_active Ceased
- 2006-03-30 NZ NZ561387A patent/NZ561387A/en not_active IP Right Cessation
- 2006-03-30 CA CA2603185A patent/CA2603185C/en not_active Expired - Fee Related
- 2006-03-30 SI SI200631472T patent/SI1864976T1/sl unknown
- 2006-03-30 PT PT67305896T patent/PT1864976E/pt unknown
- 2006-03-30 RU RU2007140244/04A patent/RU2404973C2/ru not_active IP Right Cessation
- 2006-03-30 BR BRPI0609625-5A patent/BRPI0609625A2/pt not_active Application Discontinuation
- 2006-03-30 TW TW095111211A patent/TW200722420A/zh not_active IP Right Cessation
- 2006-03-30 DK DK06730589.6T patent/DK1864976T3/da active
-
2007
- 2007-09-11 IL IL185926A patent/IL185926A/en not_active IP Right Cessation
- 2007-10-30 NO NO20075482A patent/NO341019B1/no not_active IP Right Cessation
-
2008
- 2008-03-18 HK HK08103132.5A patent/HK1109152A1/xx not_active IP Right Cessation
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2012
- 2012-12-27 CY CY20121101266T patent/CY1113504T1/el unknown
Also Published As
Publication number | Publication date |
---|---|
JP4715845B2 (ja) | 2011-07-06 |
US7960562B2 (en) | 2011-06-14 |
WO2006106812A1 (ja) | 2006-10-12 |
AU2006232469A1 (en) | 2006-10-12 |
HK1109152A1 (en) | 2008-05-30 |
US20090181964A1 (en) | 2009-07-16 |
JPWO2006106812A1 (ja) | 2008-09-11 |
RU2007140244A (ru) | 2009-05-10 |
ES2392859T3 (es) | 2012-12-14 |
CA2603185A1 (en) | 2006-10-12 |
NO341019B1 (no) | 2017-08-07 |
NZ561387A (en) | 2010-07-30 |
KR101046039B1 (ko) | 2011-07-01 |
TW200722420A (en) | 2007-06-16 |
DK1864976T3 (da) | 2012-10-22 |
KR20070119716A (ko) | 2007-12-20 |
SI1864976T1 (sl) | 2012-12-31 |
EP1864976A1 (en) | 2007-12-12 |
BRPI0609625A2 (pt) | 2010-04-20 |
IL185926A (en) | 2014-02-27 |
EP1864976B1 (en) | 2012-10-10 |
PL1864976T3 (pl) | 2013-03-29 |
EP1864976A4 (en) | 2008-05-07 |
TWI359809B (el) | 2012-03-11 |
NO20075482L (no) | 2007-12-19 |
RU2404973C2 (ru) | 2010-11-27 |
CA2603185C (en) | 2011-07-26 |
IL185926A0 (en) | 2008-01-06 |
AU2006232469B2 (en) | 2011-03-31 |
PT1864976E (pt) | 2013-01-04 |
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