AU3430699A - Butenolide derivatives as anti-cancer agents - Google Patents

Butenolide derivatives as anti-cancer agents

Info

Publication number
AU3430699A
AU3430699A AU34306/99A AU3430699A AU3430699A AU 3430699 A AU3430699 A AU 3430699A AU 34306/99 A AU34306/99 A AU 34306/99A AU 3430699 A AU3430699 A AU 3430699A AU 3430699 A AU3430699 A AU 3430699A
Authority
AU
Australia
Prior art keywords
cancer agents
butenolide
derivatives
butenolide derivatives
cancer
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU34306/99A
Inventor
Washington Odur Ayuko
Eric Lattmann
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB9807773.8A external-priority patent/GB9807773D0/en
Priority claimed from GBGB9813674.0A external-priority patent/GB9813674D0/en
Application filed by Individual filed Critical Individual
Publication of AU3430699A publication Critical patent/AU3430699A/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D307/56—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D307/60—Two oxygen atoms, e.g. succinic anhydride
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D307/56—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D307/66—Nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/04—Ortho-condensed systems
AU34306/99A 1998-04-08 1999-04-08 Butenolide derivatives as anti-cancer agents Abandoned AU3430699A (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
GBGB9807773.8A GB9807773D0 (en) 1998-04-08 1998-04-08 Anti-cancer agent
GB9807773 1998-04-08
GBGB9813674.0A GB9813674D0 (en) 1998-06-24 1998-06-24 Anti-cancer agent
GB9813674 1998-06-24
PCT/GB1999/001074 WO1999052888A1 (en) 1998-04-08 1999-04-08 Butenolide derivatives as anti-cancer agents

Publications (1)

Publication Number Publication Date
AU3430699A true AU3430699A (en) 1999-11-01

Family

ID=26313459

Family Applications (1)

Application Number Title Priority Date Filing Date
AU34306/99A Abandoned AU3430699A (en) 1998-04-08 1999-04-08 Butenolide derivatives as anti-cancer agents

Country Status (2)

Country Link
AU (1) AU3430699A (en)
WO (1) WO1999052888A1 (en)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2261437T3 (en) 2000-07-05 2006-11-16 Astellas Pharma Inc. DERIVATIVES OF PROPANE-1,3-DIONA.
GB0312360D0 (en) * 2003-05-30 2003-07-02 Univ Aston Novel 4-amino-2(5H)-furanones
WO2005026141A2 (en) * 2003-09-17 2005-03-24 Warner-Lambert Company Llc Process for preparation of substituted butenolides via palladium-free etherification and amination of masked mucohalic acids
RU2347781C2 (en) 2004-06-04 2009-02-27 Астеллас Фарма Инк. Propane-1,3-dione derivative and its salt
CA2603185C (en) 2005-03-31 2011-07-26 Astellas Pharma Inc. Propane-1,3-dione derivative or salt thereof
CA2689707A1 (en) * 2009-11-16 2011-05-16 Jean-Simon Diallo Identification of the novel small molecule viral sensitizer vse1 using high-throughput screening
US20180305345A1 (en) * 2015-01-26 2018-10-25 Ottawa Hospital Research Institute Compositions and methods for enhancing oncolytic virus efficacy
CN109320505B (en) * 2018-11-08 2022-08-02 海利尔药业集团股份有限公司 Preparation and application of halogenated butenolide compound with insecticidal activity
CN111196791B (en) * 2020-01-20 2022-03-08 中山大学 Chiral gamma-butyrolactone derivative and synthesis method and application thereof
CN112321402B (en) * 2020-11-10 2022-11-29 西安石油大学 Method for preparing 2-hydroxyethyl phenyl ketone by coupling two components

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HUT74179A (en) * 1993-08-19 1996-11-28 Warner Lambert Co Substituted 2(5h)furanone, 2(5h)thiophenone and 2(5h)pyrrolone derivatives, their preparation and their use as endothelin antagonists
AU6388896A (en) * 1995-07-06 1997-02-05 Warner-Lambert Company Butenolide endothelin antagonists

Also Published As

Publication number Publication date
WO1999052888A1 (en) 1999-10-21

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Legal Events

Date Code Title Description
MK6 Application lapsed section 142(2)(f)/reg. 8.3(3) - pct applic. not entering national phase