SI1392348T1 - Zdravljenje demence in nevrodegenerativnih bolezni z antagonisti lhrh v vmesnih dozah - Google Patents

Zdravljenje demence in nevrodegenerativnih bolezni z antagonisti lhrh v vmesnih dozah

Info

Publication number
SI1392348T1
SI1392348T1 SI200230730T SI200230730T SI1392348T1 SI 1392348 T1 SI1392348 T1 SI 1392348T1 SI 200230730 T SI200230730 T SI 200230730T SI 200230730 T SI200230730 T SI 200230730T SI 1392348 T1 SI1392348 T1 SI 1392348T1
Authority
SI
Slovenia
Prior art keywords
dementia
treatment
neurodegenerative diseases
lhrh antagonists
intermediate doses
Prior art date
Application number
SI200230730T
Other languages
English (en)
Inventor
Jurgen Engel
Rainer Voegeli
Original Assignee
Aeterna Zentaris Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Aeterna Zentaris Gmbh filed Critical Aeterna Zentaris Gmbh
Publication of SI1392348T1 publication Critical patent/SI1392348T1/sl

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/04Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/10Peptides having 12 to 20 amino acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/04Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/08Peptides having 5 to 11 amino acids
    • A61K38/09Luteinising hormone-releasing hormone [LHRH], i.e. Gonadotropin-releasing hormone [GnRH]; Related peptides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Epidemiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Peptides Or Proteins (AREA)
SI200230730T 2001-04-30 2002-04-27 Zdravljenje demence in nevrodegenerativnih bolezni z antagonisti lhrh v vmesnih dozah SI1392348T1 (sl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US28743401P 2001-04-30 2001-04-30
PCT/EP2002/004677 WO2002102401A1 (en) 2001-04-30 2002-04-27 Treatment of dementia and neurodegenerative diseases with intermediate doses of lhrh antagonists
EP02735312A EP1392348B1 (en) 2001-04-30 2002-04-27 Treatment of dementia and neurodegenerative diseases with intermediate doses of lhrh antagonists

Publications (1)

Publication Number Publication Date
SI1392348T1 true SI1392348T1 (sl) 2008-12-31

Family

ID=23102886

Family Applications (1)

Application Number Title Priority Date Filing Date
SI200230730T SI1392348T1 (sl) 2001-04-30 2002-04-27 Zdravljenje demence in nevrodegenerativnih bolezni z antagonisti lhrh v vmesnih dozah

Country Status (28)

Country Link
US (1) US7288517B2 (sl)
EP (1) EP1392348B1 (sl)
JP (1) JP2004529207A (sl)
KR (1) KR20040000446A (sl)
CN (1) CN1317030C (sl)
AT (1) ATE400287T1 (sl)
AU (1) AU2002310788B2 (sl)
BG (1) BG108339A (sl)
BR (1) BR0209290A (sl)
CA (1) CA2444876A1 (sl)
CZ (1) CZ20033167A3 (sl)
DE (1) DE60227507D1 (sl)
DK (1) DK1392348T3 (sl)
ES (1) ES2307760T3 (sl)
HK (1) HK1072000A1 (sl)
HU (1) HUP0400067A2 (sl)
IL (1) IL156777A0 (sl)
MX (1) MXPA03008666A (sl)
NO (1) NO20034322D0 (sl)
NZ (1) NZ544417A (sl)
PL (1) PL362319A1 (sl)
PT (1) PT1392348E (sl)
RU (1) RU2319501C2 (sl)
SI (1) SI1392348T1 (sl)
SK (1) SK14512003A3 (sl)
UA (1) UA80679C2 (sl)
WO (1) WO2002102401A1 (sl)
ZA (1) ZA200305326B (sl)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6828415B2 (en) * 1993-02-19 2004-12-07 Zentaris Gmbh Oligopeptide lyophilisate, their preparation and use
US20020077327A1 (en) * 1999-09-23 2002-06-20 Neurocrine Biosciences, Inc. Gonadotropin-releasing hormone receptor antagonists and methods relating thereto
AU2001271022B2 (en) * 2000-07-05 2006-08-17 Astellas Pharma Inc. Propane-1,3-dione derivatives
DE10137174A1 (de) * 2001-07-31 2003-02-13 Zentaris Ag Verwendung von LHRH-Antagonisten in nichtkastrierenden Dosen zur Verbesserung der T-Zellen-vermittelten Immunität
EP1752452A4 (en) * 2004-06-04 2010-07-14 Astellas Pharma Inc DERIVATIVE OF PROPANE-1, 3-DIONE OR ITS SALT
US20080171736A1 (en) * 2004-12-23 2008-07-17 Gregory Christopher W Treatment of Alzheimer's Disease and Mild Cognitive impairment using GnRH-I analogs and one or more of acetylcholinesterase inhibitors and NMDA receptor antagonists
CN101087618A (zh) * 2004-12-23 2007-12-12 航行药物公司 醋酸亮丙瑞林和乙酰胆碱酯酶抑制剂或nmda受体抑制剂在阿尔茨海默氏病治疗中的应用
KR101046039B1 (ko) 2005-03-31 2011-07-01 아스텔라스세이야쿠 가부시키가이샤 프로판-1,3-디온 유도체 또는 그의 염
EP2091943B1 (en) 2006-10-21 2013-11-20 AbbVie Deutschland GmbH & Co KG Heterocyclic compounds and their use as glycogen synthase kinase 3 inhibitors
JP5385282B2 (ja) * 2007-09-11 2014-01-08 モンドバイオテック ラボラトリーズ アクチエンゲゼルシャフト 治療剤としての血小板フィブリノーゲン受容体ヘキサペプチドアンタゴニストおよびα−エンドルフィンの使用
CA2698768A1 (en) * 2007-09-11 2009-04-02 Dorian Bevec Use of a peptide as a therapeutic agent
EP2095818A1 (en) 2008-02-29 2009-09-02 AEterna Zentaris GmbH Use of LHRH antagonists at non-castrating doses
EP2307040B1 (en) * 2008-05-29 2015-09-09 Isr Immune System Regulation Ab Use of gnrh and sex hormones for treating viral disease, in particular hiv/aids
WO2012041814A1 (en) 2010-09-27 2012-04-05 Abbott Gmbh & Co. Kg Heterocyclic compounds and their use as glycogen synthase kinase-3 inhibitors
US9090592B2 (en) 2010-12-30 2015-07-28 AbbVie Deutschland GmbH & Co. KG Heterocyclic compounds and their use as glycogen synthase kinase-3 inhibitors
EP3560555A1 (en) * 2018-04-26 2019-10-30 LifeArc A composition for treating one or more estrogen related diseases

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3135743A (en) 1960-06-29 1964-06-02 Sterling Drug Inc Steroido[2. 3-d]isoxazoles and preparation thereof
WO1997044339A1 (en) * 1996-05-20 1997-11-27 Merck & Co., Inc. Antagonists of gonadotropin releasing hormone
DE19911771B4 (de) 1999-03-17 2006-03-30 Zentaris Gmbh LHRH-Antagonist, Verfahren zu seiner Herstellung und seiner Verwendung
AU767440B2 (en) 1999-05-14 2003-11-13 Neurocrine Biosciences, Inc. Imidazo- and pyrrolo(1,2-A)pyrimid-4-ones as gonadotropin-releasing hormone receptor antagonists
CA2309395A1 (en) 1999-06-04 2000-12-04 Richard Lloyd Bowen Methods for preventing and treating alzheimer's disease
KR20020045609A (ko) 1999-10-15 2002-06-19 추후기재 고나도트로핀-분비 호르몬 수용체 길항제 및 이와 관련된방법
EP1393747A4 (en) 2000-04-13 2004-03-03 Takeda Chemical Industries Ltd AGENT FOR PREVENTION / TREATMENT OF ALZHEIMER DISEASE
AU2001271022B2 (en) 2000-07-05 2006-08-17 Astellas Pharma Inc. Propane-1,3-dione derivatives

Also Published As

Publication number Publication date
SK14512003A3 (sk) 2004-08-03
MXPA03008666A (es) 2004-10-15
AU2002310788B2 (en) 2007-04-05
EP1392348B1 (en) 2008-07-09
DE60227507D1 (de) 2008-08-21
RU2003134949A (ru) 2005-02-10
US7288517B2 (en) 2007-10-30
PT1392348E (pt) 2008-09-09
UA80679C2 (en) 2007-10-25
IL156777A0 (en) 2004-02-08
ATE400287T1 (de) 2008-07-15
CA2444876A1 (en) 2002-12-27
NZ544417A (en) 2008-03-28
HK1072000A1 (en) 2005-08-12
HUP0400067A2 (hu) 2004-04-28
EP1392348A1 (en) 2004-03-03
ZA200305326B (en) 2003-07-30
DK1392348T3 (da) 2008-09-29
BR0209290A (pt) 2004-07-13
CN1317030C (zh) 2007-05-23
NO20034322L (no) 2003-09-26
RU2319501C2 (ru) 2008-03-20
BG108339A (bg) 2004-11-30
CZ20033167A3 (cs) 2004-08-18
US20020177556A1 (en) 2002-11-28
JP2004529207A (ja) 2004-09-24
PL362319A1 (en) 2004-10-18
NO20034322D0 (no) 2003-09-26
CN1575185A (zh) 2005-02-02
ES2307760T3 (es) 2008-12-01
WO2002102401A1 (en) 2002-12-27
KR20040000446A (ko) 2004-01-03

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