CY1113477T1 - Ετερολογος εκφραση πρωτεϊνων της neisseria - Google Patents
Ετερολογος εκφραση πρωτεϊνων της neisseriaInfo
- Publication number
- CY1113477T1 CY1113477T1 CY20121100861T CY121100861T CY1113477T1 CY 1113477 T1 CY1113477 T1 CY 1113477T1 CY 20121100861 T CY20121100861 T CY 20121100861T CY 121100861 T CY121100861 T CY 121100861T CY 1113477 T1 CY1113477 T1 CY 1113477T1
- Authority
- CY
- Cyprus
- Prior art keywords
- expression
- neisseria
- neisseria protein
- approaches
- protein expression
- Prior art date
Links
- 102000004169 proteins and genes Human genes 0.000 title abstract 3
- 108090000623 proteins and genes Proteins 0.000 title abstract 3
- 241000588653 Neisseria Species 0.000 title 1
- 238000013459 approach Methods 0.000 abstract 2
- 241000588652 Neisseria gonorrhoeae Species 0.000 abstract 1
- 241000588650 Neisseria meningitidis Species 0.000 abstract 1
- 230000001413 cellular effect Effects 0.000 abstract 1
- 230000001900 immune effect Effects 0.000 abstract 1
- 238000000746 purification Methods 0.000 abstract 1
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/02—Bacterial antigens
- A61K39/095—Neisseria
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
- C07K14/22—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Neisseriaceae (F)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P21/00—Preparation of peptides or proteins
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P21/00—Preparation of peptides or proteins
- C12P21/02—Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6888—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms
- C12Q1/689—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms for bacteria
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/545—Medicinal preparations containing antigens or antibodies characterised by the dose, timing or administration schedule
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55505—Inorganic adjuvants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/57—Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2
- A61K2039/572—Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2 cytotoxic response
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/57—Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2
- A61K2039/575—Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2 humoral response
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/156—Polymorphic or mutational markers
Abstract
Εναλλακτικές προσεγγίσεις της ετερόλογου έκφρασης των πρωτεϊνών Neisseria meningitidis και τη Neisseria gonorrhoeae. Αυτές οι προσεγγίσεις συνήθως επηρεάζουν το επίπεδο έκφρασης, την ευκολία καθαρισμού, την κυτταρική τοποθέτηση, και/ή τις ανοσολογικές ιδιότητες της εκφραζόμενης πρωτεΐνης.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB0004695A GB0004695D0 (en) | 2000-02-28 | 2000-02-28 | Protein expression |
GB0027675A GB0027675D0 (en) | 2000-11-13 | 2000-11-13 | Protein Expression |
EP06076718A EP1790660B1 (en) | 2000-02-28 | 2001-02-28 | Heterologous expression of neisserial proteins |
Publications (1)
Publication Number | Publication Date |
---|---|
CY1113477T1 true CY1113477T1 (el) | 2016-06-22 |
Family
ID=26243750
Family Applications (6)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CY20071100540T CY1106532T1 (el) | 2000-02-28 | 2007-04-19 | Ετερολογος εκφραση των πρωτεϊνων της neisseria |
CY20081100464T CY1107447T1 (el) | 2000-02-28 | 2008-04-30 | Ετερολογη εκφραση πρωτεϊνων των neisseria |
CY20111100604T CY1111591T1 (el) | 2000-02-28 | 2011-06-27 | Υβριδικη εκφραση πρωτεϊνων των neisseria |
CY20121100728T CY1113032T1 (el) | 2000-02-28 | 2012-08-13 | Ετερολογη εκφραση πρωτεϊνων νειssεrια |
CY20121100861T CY1113477T1 (el) | 2000-02-28 | 2012-09-19 | Ετερολογος εκφραση πρωτεϊνων της neisseria |
CY2013025C CY2013025I1 (el) | 2000-02-28 | 2013-07-03 | Ετερολογος εκφραση των πρωτεϊνων της neisseria |
Family Applications Before (4)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CY20071100540T CY1106532T1 (el) | 2000-02-28 | 2007-04-19 | Ετερολογος εκφραση των πρωτεϊνων της neisseria |
CY20081100464T CY1107447T1 (el) | 2000-02-28 | 2008-04-30 | Ετερολογη εκφραση πρωτεϊνων των neisseria |
CY20111100604T CY1111591T1 (el) | 2000-02-28 | 2011-06-27 | Υβριδικη εκφραση πρωτεϊνων των neisseria |
CY20121100728T CY1113032T1 (el) | 2000-02-28 | 2012-08-13 | Ετερολογη εκφραση πρωτεϊνων νειssεrια |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CY2013025C CY2013025I1 (el) | 2000-02-28 | 2013-07-03 | Ετερολογος εκφραση των πρωτεϊνων της neisseria |
Country Status (20)
Country | Link |
---|---|
US (9) | US20040092711A1 (el) |
EP (6) | EP1261723B1 (el) |
JP (8) | JP4763210B2 (el) |
CN (7) | CN100473663C (el) |
AT (3) | ATE503837T1 (el) |
AU (4) | AU3947801A (el) |
BR (2) | BR0108711A (el) |
CA (5) | CA2400562C (el) |
CY (6) | CY1106532T1 (el) |
DE (3) | DE60144353D1 (el) |
DK (4) | DK1261723T3 (el) |
ES (5) | ES2299476T3 (el) |
HK (4) | HK1055993A1 (el) |
LU (1) | LU92240I2 (el) |
MX (2) | MXPA02008313A (el) |
NL (1) | NL300605I2 (el) |
NZ (2) | NZ521531A (el) |
PT (4) | PT1947187E (el) |
RU (2) | RU2299906C2 (el) |
WO (2) | WO2001064922A2 (el) |
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EP2261351A3 (en) | 1998-05-01 | 2012-01-11 | Novartis Vaccines and Diagnostics, Inc. | Neisseria meningitidis antigens and compositions |
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CA2371994C (en) * | 1999-02-26 | 2010-09-28 | Guido Grandi | Enhancement of bactericidal activity of neisseria antigens with oligonucleotides containing cg motifs |
ES2477194T3 (es) | 1999-04-30 | 2014-07-16 | Novartis Vaccines And Diagnostics S.R.L. | Ant�genos neisseriales conservados |
GB9911683D0 (en) * | 1999-05-19 | 1999-07-21 | Chiron Spa | Antigenic peptides |
EP2270172B1 (en) | 1999-05-19 | 2016-01-13 | GlaxoSmithKline Biologicals SA | Combination neisserial compositions |
CN1796404A (zh) | 1999-10-29 | 2006-07-05 | 启龙有限公司 | 奈瑟球菌的抗原性肽 |
GB9928196D0 (en) | 1999-11-29 | 2000-01-26 | Chiron Spa | Combinations of B, C and other antigens |
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ATE503837T1 (de) | 2000-02-28 | 2011-04-15 | Novartis Vaccines & Diagnostic | Hybride expression neisserscher proteine |
CA2439428C (en) * | 2001-04-17 | 2012-01-24 | Chiron Corporation | Molecular mimetics of meningococcal b epitopes which elicit functionally active antibodies |
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GB0118249D0 (en) | 2001-07-26 | 2001-09-19 | Chiron Spa | Histidine vaccines |
GB0121591D0 (en) | 2001-09-06 | 2001-10-24 | Chiron Spa | Hybrid and tandem expression of neisserial proteins |
CA2452836C (en) * | 2001-07-27 | 2012-11-27 | Chiron Srl | Meningococcus adhesins nada, app and orf 40 |
AU2014201962B2 (en) * | 2001-09-06 | 2016-06-09 | Novartis Vaccines And Diagnostics S.R.L. | Hybrid and tandem expression of Neisserial proteins |
AR045702A1 (es) | 2001-10-03 | 2005-11-09 | Chiron Corp | Composiciones de adyuvantes. |
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- 2010-12-24 JP JP2010288968A patent/JP5346004B2/ja not_active Expired - Fee Related
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2011
- 2011-01-12 JP JP2011004414A patent/JP2011101657A/ja active Pending
- 2011-06-27 CY CY20111100604T patent/CY1111591T1/el unknown
- 2011-12-29 US US13/340,549 patent/US8703914B2/en not_active Expired - Fee Related
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2012
- 2012-08-13 CY CY20121100728T patent/CY1113032T1/el unknown
- 2012-09-19 CY CY20121100861T patent/CY1113477T1/el unknown
- 2012-09-27 JP JP2012214120A patent/JP2013005816A/ja not_active Withdrawn
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2013
- 2013-07-03 CY CY2013025C patent/CY2013025I1/el unknown
- 2013-07-04 LU LU92240C patent/LU92240I2/fr unknown
- 2013-07-15 NL NL300605C patent/NL300605I2/nl unknown
- 2013-09-18 JP JP2013192617A patent/JP5941027B2/ja not_active Expired - Fee Related
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2014
- 2014-03-18 JP JP2014054817A patent/JP2014121333A/ja active Pending
- 2014-04-03 US US14/244,806 patent/US20140294885A1/en not_active Abandoned
- 2014-07-31 US US14/448,792 patent/US9150898B2/en not_active Expired - Fee Related
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2016
- 2016-04-11 JP JP2016078708A patent/JP2016128520A/ja active Pending
- 2016-12-02 US US15/368,429 patent/US20170080076A1/en not_active Abandoned
- 2016-12-02 US US15/368,435 patent/US20170080077A1/en not_active Abandoned
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