BR0213119A - Composição imunogênica e uso da mesma - Google Patents

Composição imunogênica e uso da mesma

Info

Publication number
BR0213119A
BR0213119A BR0213119-6A BR0213119A BR0213119A BR 0213119 A BR0213119 A BR 0213119A BR 0213119 A BR0213119 A BR 0213119A BR 0213119 A BR0213119 A BR 0213119A
Authority
BR
Brazil
Prior art keywords
immunogenic composition
neisserial
composition
cpg
meningococo
Prior art date
Application number
BR0213119-6A
Other languages
English (en)
Inventor
Derek O'hagan
Nicholas Valiante
Original Assignee
Chiron Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from PCT/US2002/010869 external-priority patent/WO2002080648A2/en
Application filed by Chiron Corp filed Critical Chiron Corp
Publication of BR0213119A publication Critical patent/BR0213119A/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/02—Bacterial antigens
    • A61K39/095—Neisseria
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/39—Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511—Organic adjuvants
    • A61K2039/55555—Liposomes; Vesicles, e.g. nanoparticles; Spheres, e.g. nanospheres; Polymers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511—Organic adjuvants
    • A61K2039/55561—CpG containing adjuvants; Oligonucleotide containing adjuvants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511—Organic adjuvants
    • A61K2039/55566—Emulsions, e.g. Freund's adjuvant, MF59
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/60—Medicinal preparations containing antigens or antibodies characteristics by the carrier linked to the antigen
    • A61K2039/6093—Synthetic polymers, e.g. polyethyleneglycol [PEG], Polymers or copolymers of (D) glutamate and (D) lysine

Abstract

"COMPOSIçõES ADJUVANTES DE MENINGOCOCO". Trata-se de uma combinação de oligonucleotídeos CpG e micropartículas poliméricas, que consiste de um adjuvante extremamente eficaz para os antígenos de Neisserial. A invenção, por conseguinte, proporciona uma composição que compreende: (a) um antígeno Neisserial; (b) um oligonucleotídeo CpG; e (c) uma micropartícula polimérica biodegradável.
BR0213119-6A 2001-10-03 2002-10-03 Composição imunogênica e uso da mesma BR0213119A (pt)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US32692901P 2001-10-03 2001-10-03
PCT/US2002/010869 WO2002080648A2 (en) 2001-04-05 2002-04-05 Mucosal boosting following parenteral priming
US37354702P 2002-04-17 2002-04-17
US38067702P 2002-05-13 2002-05-13
US25443802A 2002-09-24 2002-09-24
US0230423 2002-09-24
PCT/US2002/031726 WO2003028661A2 (en) 2001-10-03 2002-10-03 Adjuvanted meningococcus compositions

Publications (1)

Publication Number Publication Date
BR0213119A true BR0213119A (pt) 2004-12-28

Family

ID=32601151

Family Applications (1)

Application Number Title Priority Date Filing Date
BR0213119-6A BR0213119A (pt) 2001-10-03 2002-10-03 Composição imunogênica e uso da mesma

Country Status (8)

Country Link
EP (1) EP1438323A4 (pt)
JP (1) JP4522699B2 (pt)
CN (1) CN100354297C (pt)
AU (1) AU2002334844B2 (pt)
BR (1) BR0213119A (pt)
CA (1) CA2462646C (pt)
NZ (1) NZ532274A (pt)
WO (1) WO2003028661A2 (pt)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0115176D0 (en) 2001-06-20 2001-08-15 Chiron Spa Capular polysaccharide solubilisation and combination vaccines
DE60328481D1 (de) * 2002-05-14 2009-09-03 Novartis Vaccines & Diagnostic Schleimhautapplizierter impfstoff, der das adjuvanz chitosan und menigokokkenantigene enthält
GB0302218D0 (en) 2003-01-30 2003-03-05 Chiron Sri Vaccine formulation & Mucosal delivery
CA2493977A1 (en) * 2002-08-02 2004-02-19 Glaxosmithkline Biologicals Sa Vaccine composition comprising lipooligosaccharide with reduced phase variability
JP2006520746A (ja) 2002-12-27 2006-09-14 カイロン コーポレイション リン脂質を含む免疫原性組成物
WO2004075829A2 (en) * 2003-01-30 2004-09-10 Chiron Corporation Adjuvanted influenza vaccine
PT1587537E (pt) 2003-01-30 2012-05-30 Novartis Ag Vacinas injetáveis contra múltiplos serogrupos meningocócicos
US7731967B2 (en) 2003-04-30 2010-06-08 Novartis Vaccines And Diagnostics, Inc. Compositions for inducing immune responses
US9107831B2 (en) 2003-06-02 2015-08-18 Novartis Vaccines And Diagonstics, Inc. Immunogenic compositions containing microparticles comprising adsorbed toxoid and polysaccharide-containing antigens
EP1725266A4 (en) * 2004-02-20 2008-05-07 Hybridon Inc POWERFUL MUCOSAL IMMUNE RESPONSE INDUCED BY MODIFIED IMMUNOMODULATORY OLIGONUCLEOTIDES
ES2434029T3 (es) 2004-11-15 2013-12-13 Novartis Vaccines And Diagnostics, Inc. Composiciones inmunogénicas que contiene antígeno de antrax, micropartículas de polímero biodegradable, y adyuvante inmunológico que contiene polinucleótido
ZA200707249B (en) 2005-01-28 2010-08-25 Galen Bio Inc Immunologically active compositions
DE602006008278D1 (de) * 2005-03-02 2009-09-17 Pharmazeutische zusammensetzung
US8815253B2 (en) 2007-12-07 2014-08-26 Novartis Ag Compositions for inducing immune responses
CN101559225B (zh) * 2008-04-18 2012-07-11 北京生物制品研究所 脑膜炎球菌疫苗
CA3211102A1 (en) * 2012-06-21 2013-12-27 Northwestern University Peptide conjugated particles

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6239116B1 (en) * 1994-07-15 2001-05-29 University Of Iowa Research Foundation Immunostimulatory nucleic acid molecules
EP1900818A3 (en) * 1997-11-06 2008-06-11 Novartis Vaccines and Diagnostics S.r.l. Neisserial antigens
ES2333071T5 (es) * 1998-01-14 2015-08-17 Novartis Vaccines And Diagnostics S.R.L. Antígenos de Neisseria meningitidis
ES2294629T3 (es) * 1998-05-01 2008-04-01 Novartis Vaccines And Diagnostics, Inc. Antigenos de neisseria y composiciones.
AU763975B2 (en) * 1998-07-29 2003-08-07 Novartis Vaccines And Diagnostics, Inc. Microparticles with adsorbent surfaces, methods of making same, and uses thereof
AU1202200A (en) * 1998-10-09 2000-05-01 Chiron Corporation Neisseria genomic sequences and methods of their use
DE60015084T2 (de) * 1999-02-26 2006-02-16 Chiron S.R.L. Verbesserung der bakterizidaktivität von neisseria antigenen mit cg enthaltende oligonukleotiden
CA2363141C (en) * 1999-02-26 2010-04-06 Chiron Corporation Microemulsions with adsorbed macromolecules and microparticles
PT1228217E (pt) * 1999-04-30 2013-01-28 Novartis Vaccines & Diagnostic Antígenos de neisseria conservados
AU3948801A (en) * 2000-02-28 2001-09-12 Chiron Spa Heterologous expression of neisserial proteins

Also Published As

Publication number Publication date
CA2462646C (en) 2013-02-12
AU2002334844B2 (en) 2007-08-02
JP4522699B2 (ja) 2010-08-11
EP1438323A2 (en) 2004-07-21
JP2005526697A (ja) 2005-09-08
WO2003028661A3 (en) 2003-10-09
NZ532274A (en) 2006-02-24
EP1438323A4 (en) 2007-08-01
WO2003028661A2 (en) 2003-04-10
CN1599746A (zh) 2005-03-23
CN100354297C (zh) 2007-12-12
AU2002334844B8 (en) 2003-04-14
CA2462646A1 (en) 2003-04-10

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Legal Events

Date Code Title Description
B06G Technical and formal requirements: other requirements

Free format text: APRESENTE O DEPOSITANTE NOVAS FOLHAS DE DECLARACAO DAS PRIORIDADES NOS US 10/254.438 DE 24/09/2002E PCT/US02/30423 DE 24/09/2002, ASSINADAS.

B25D Requested change of name of applicant approved

Owner name: NOVARTIS VACCINES AND DIAGNOSTICS, INC. (US)

Free format text: ALTERADO DE: CHIRON CORPORATION

B06F Objections, documents and/or translations needed after an examination request according art. 34 industrial property law
B08F Application fees: dismissal - article 86 of industrial property law

Free format text: REFERENTE A 12A ANUIDADE.

B08K Lapse as no evidence of payment of the annual fee has been furnished to inpi (acc. art. 87)

Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 2274 DE 05/08/2014.