BR9808772A - Composição de vacina multivalente com carreadora misturada - Google Patents
Composição de vacina multivalente com carreadora misturadaInfo
- Publication number
- BR9808772A BR9808772A BR9808772-0A BR9808772A BR9808772A BR 9808772 A BR9808772 A BR 9808772A BR 9808772 A BR9808772 A BR 9808772A BR 9808772 A BR9808772 A BR 9808772A
- Authority
- BR
- Brazil
- Prior art keywords
- composition
- multivalent vaccine
- mixed carrier
- conjugates
- carrier protein
- Prior art date
Links
- 239000000203 mixture Substances 0.000 title abstract 3
- 229940031348 multivalent vaccine Drugs 0.000 title abstract 2
- 102000014914 Carrier Proteins Human genes 0.000 abstract 2
- 108010078791 Carrier Proteins Proteins 0.000 abstract 2
- 239000003795 chemical substances by application Substances 0.000 abstract 2
- 150000004676 glycans Chemical class 0.000 abstract 2
- 229920001282 polysaccharide Polymers 0.000 abstract 2
- 239000005017 polysaccharide Substances 0.000 abstract 2
- 241000894006 Bacteria Species 0.000 abstract 1
- 230000002163 immunogen Effects 0.000 abstract 1
- 208000015181 infectious disease Diseases 0.000 abstract 1
- 244000052769 pathogen Species 0.000 abstract 1
- 230000001717 pathogenic effect Effects 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/02—Bacterial antigens
- A61K39/09—Lactobacillales, e.g. aerococcus, enterococcus, lactobacillus, lactococcus, streptococcus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/02—Bacterial antigens
- A61K39/09—Lactobacillales, e.g. aerococcus, enterococcus, lactobacillus, lactococcus, streptococcus
- A61K39/092—Streptococcus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/60—Medicinal preparations containing antigens or antibodies characteristics by the carrier linked to the antigen
- A61K2039/6031—Proteins
- A61K2039/6037—Bacterial toxins, e.g. diphteria toxoid [DT], tetanus toxoid [TT]
Abstract
<B>COMPOSIçãO DE VACINA MULTIVALENTE COM CARREADORA MISTURADA<D> A invenção refere-se a uma composição farmacêutica para tratar ou impedir um certo número de infecções provocadas por agentes patogênicos tais como bactérias, compreendendo, como agente imunogênico, um ou diversos polissacarídeos obtidos a partir de um ou de diversos agentes patogênicos. Os polissacarídeos estão sob a forma de conjugados, acoplados a uma proteína carreadora. A composição contém, pelo menos, dois tipos de conjugados, sendo cada um deles caracterizado por, pelo menos, uma proteína carreadora diferente.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR9706210A FR2763244B1 (fr) | 1997-05-14 | 1997-05-14 | Composition vaccinale multivalente a porteur mixte |
PCT/FR1998/000966 WO1998051339A1 (fr) | 1997-05-14 | 1998-05-14 | Composition vaccinale multivalente a porteur mixte |
Publications (1)
Publication Number | Publication Date |
---|---|
BR9808772A true BR9808772A (pt) | 2000-09-05 |
Family
ID=9507086
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR9808772-0A BR9808772A (pt) | 1997-05-14 | 1998-05-14 | Composição de vacina multivalente com carreadora misturada |
Country Status (20)
Country | Link |
---|---|
US (2) | US7862823B1 (pt) |
EP (1) | EP0983087B1 (pt) |
JP (1) | JP2001525815A (pt) |
KR (1) | KR100709628B1 (pt) |
CN (1) | CN1154509C (pt) |
AT (1) | ATE279942T1 (pt) |
AU (1) | AU748716B2 (pt) |
BR (1) | BR9808772A (pt) |
CA (1) | CA2289009C (pt) |
CZ (1) | CZ295272B6 (pt) |
DE (1) | DE69827127T2 (pt) |
ES (1) | ES2227840T3 (pt) |
FR (1) | FR2763244B1 (pt) |
HU (1) | HUP0002322A3 (pt) |
IL (3) | IL132669A0 (pt) |
NO (1) | NO320415B1 (pt) |
NZ (1) | NZ500738A (pt) |
PL (1) | PL189653B1 (pt) |
PT (1) | PT983087E (pt) |
WO (1) | WO1998051339A1 (pt) |
Families Citing this family (46)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP1034792A1 (en) * | 1999-03-11 | 2000-09-13 | Pasteur Merieux Serums Et Vaccins | Intranasal delivery of pneumococcal polysaccharide vaccines |
SI1162999T1 (sl) * | 1999-03-19 | 2007-04-30 | Glaxosmithkline Biolog Sa | Vakcina proti Streptococcus pneumoniae |
GB9909077D0 (en) * | 1999-04-20 | 1999-06-16 | Smithkline Beecham Biolog | Novel compositions |
FR2806304B1 (fr) * | 2000-03-17 | 2002-05-10 | Aventis Pasteur | Conjugues polysaccharidiques du pneumocoque a usage vaccinal contre le tetanos et la diphterie |
GB0108364D0 (en) * | 2001-04-03 | 2001-05-23 | Glaxosmithkline Biolog Sa | Vaccine composition |
GB0022742D0 (en) * | 2000-09-15 | 2000-11-01 | Smithkline Beecham Biolog | Vaccine |
GB0130215D0 (en) * | 2001-12-18 | 2002-02-06 | Glaxosmithkline Biolog Sa | Vaccine |
FR2850106B1 (fr) | 2003-01-17 | 2005-02-25 | Aventis Pasteur | Conjugues obtenus par amination reductrice du polysaccharide capsulaire du pneumocoque de serotype 5 |
PL1740217T3 (pl) | 2004-04-30 | 2012-03-30 | Novartis Ag | Szczepienie koniugatem meningokokowym |
GB0409745D0 (en) | 2004-04-30 | 2004-06-09 | Chiron Srl | Compositions including unconjugated carrier proteins |
GB0500787D0 (en) | 2005-01-14 | 2005-02-23 | Chiron Srl | Integration of meningococcal conjugate vaccination |
GB0419846D0 (en) * | 2004-09-07 | 2004-10-13 | Chiron Srl | Vaccine adjuvants for saccharides |
US7955605B2 (en) | 2005-04-08 | 2011-06-07 | Wyeth Llc | Multivalent pneumococcal polysaccharide-protein conjugate composition |
EP2425851A1 (en) | 2005-04-08 | 2012-03-07 | Wyeth LLC | Multivalent Pneumococcal Polysaccharide-Protein Conjugate Composition |
US7709001B2 (en) | 2005-04-08 | 2010-05-04 | Wyeth Llc | Multivalent pneumococcal polysaccharide-protein conjugate composition |
US20070184072A1 (en) | 2005-04-08 | 2007-08-09 | Wyeth | Multivalent pneumococcal polysaccharide-protein conjugate composition |
SI1896065T2 (sl) | 2005-06-27 | 2014-12-31 | Glaxosmithkline Biologicals S.A. | Postopek za pripravo cepiv |
JP5135220B2 (ja) | 2005-09-01 | 2013-02-06 | ノバルティス ヴァクシンズ アンド ダイアグノスティクス ゲーエムベーハー アンド カンパニー カーゲー | 血清群c髄膜炎菌を含む複数ワクチン接種 |
ES2707499T3 (es) | 2005-12-22 | 2019-04-03 | Glaxosmithkline Biologicals Sa | Vacuna de conjugado de polisacárido neumocócico |
TW200806315A (en) * | 2006-04-26 | 2008-02-01 | Wyeth Corp | Novel formulations which stabilize and inhibit precipitation of immunogenic compositions |
US8808707B1 (en) | 2006-05-08 | 2014-08-19 | Wyeth Llc | Pneumococcal dosing regimen |
CN103933564A (zh) | 2007-05-02 | 2014-07-23 | 葛兰素史密丝克莱恩生物有限公司 | 疫苗 |
EP2170391B1 (en) * | 2007-06-20 | 2017-01-18 | Pfizer Ireland Pharmaceuticals | Modified polysaccharides for conjugate vaccines |
RS54349B1 (en) | 2007-06-26 | 2016-02-29 | Glaxosmithkline Biologicals S.A. | VACCINE CONTAINING STREPTOCOCCUS PNEUMONIAE Capsular POLYSACCHARIDE CONJUGATES |
EP2547357A1 (en) | 2010-03-18 | 2013-01-23 | Novartis AG | Adjuvanted vaccines for serogroup b meningococcus |
BR112013005049A2 (pt) | 2010-09-02 | 2016-05-31 | Sanofi Pasteur | estabilizador para a preparação de uma composição vacina da pólio seca injetável |
GB201101665D0 (en) | 2011-01-31 | 2011-03-16 | Novartis Ag | Immunogenic compositions |
TR201900778T4 (tr) * | 2012-01-30 | 2019-02-21 | Serum Institute Of India Private Ltd | İmmünojenik bileşim. |
CN104582718B (zh) | 2012-10-03 | 2017-10-24 | 诺华股份有限公司 | 免疫原性组合物 |
WO2016012385A1 (en) | 2014-07-21 | 2016-01-28 | Sanofi Pasteur | Vaccine composition comprising ipv and cyclodextrins |
US9107906B1 (en) | 2014-10-28 | 2015-08-18 | Adma Biologics, Inc. | Compositions and methods for the treatment of immunodeficiency |
CN105695497B (zh) * | 2014-11-27 | 2019-09-24 | 中国人民解放军军事医学科学院生物工程研究所 | 一种细菌多糖修饰的重组融合蛋白的制备方法及其应用 |
EP3313436B1 (en) | 2015-06-23 | 2020-12-23 | Biological E Limited | Multivalent pneumococcal conjugate vaccine |
CN109862908B (zh) * | 2016-08-05 | 2023-05-02 | 圣诺菲·帕斯图尔公司 | 多价肺炎球菌多糖-蛋白质缀合物组合物 |
MX2019001341A (es) * | 2016-08-05 | 2019-07-04 | Sanofi Pasteur Inc | Composicion de conjugado de polisacarido neumococico multivalente-proteina. |
KR102608081B1 (ko) * | 2016-09-30 | 2023-11-29 | 바이오로지칼 이 리미티드 | 폴리사카라이드-단백질 접합체를 포함하는 다가 폐렴구균 백신 조성물 |
US11951165B2 (en) | 2016-12-30 | 2024-04-09 | Vaxcyte, Inc. | Conjugated vaccine carrier proteins |
US10259865B2 (en) | 2017-03-15 | 2019-04-16 | Adma Biologics, Inc. | Anti-pneumococcal hyperimmune globulin for the treatment and prevention of pneumococcal infection |
BR112019026192B1 (pt) | 2017-06-10 | 2022-05-10 | Inventprise, Llc | Vacinas de conjugado multivalente com polissacarídeos de conjugado bivalente ou multivalente que fornecem imunogenicidade e avidez melhoradas |
US10729763B2 (en) | 2017-06-10 | 2020-08-04 | Inventprise, Llc | Mixtures of polysaccharide-protein pegylated compounds |
US11123417B2 (en) * | 2018-02-05 | 2021-09-21 | Sanofi Pasteur Inc. | Multivalent pneumococcal polysaccharide-protein conjugate composition |
CN111757754A (zh) * | 2018-02-05 | 2020-10-09 | 赛诺菲巴斯德有限公司 | 多价肺炎球菌多糖-蛋白质缀合物组合物 |
CA3096358A1 (en) | 2018-04-18 | 2019-10-24 | Sk Bioscience Co., Ltd. | Streptococcus pneumoniae capsular polysaccharide and immunogenic conjugate thereof |
WO2020010016A1 (en) | 2018-07-04 | 2020-01-09 | Sutrovax, Inc. | Self-adjuvanted immunogenic conjugates |
WO2020009993A1 (en) | 2018-07-04 | 2020-01-09 | Sutrovax, Inc. | Improvements in immunogenic conjugates |
WO2023200704A1 (en) | 2022-04-11 | 2023-10-19 | Sanofi Pasteur Inc. | Protein-saccharide conjugation with sodium cyanoborohydride |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS5639022A (en) * | 1979-09-05 | 1981-04-14 | Hayashibara Biochem Lab Inc | Preparation of vaccine |
NZ220932A (en) * | 1986-07-03 | 1990-05-28 | Victoria State | Composition comprising an antigenic substance, such as lhrh, conjugated to at least two different carriers and method of immunological castration and spaying |
CA2059692C (en) * | 1991-01-28 | 2004-11-16 | Peter J. Kniskern | Pneumoccoccal polysaccharide conjugate vaccine |
SI1162999T1 (sl) | 1999-03-19 | 2007-04-30 | Glaxosmithkline Biolog Sa | Vakcina proti Streptococcus pneumoniae |
GB0130215D0 (en) | 2001-12-18 | 2002-02-06 | Glaxosmithkline Biolog Sa | Vaccine |
-
1997
- 1997-05-14 FR FR9706210A patent/FR2763244B1/fr not_active Expired - Lifetime
-
1998
- 1998-05-14 DE DE69827127T patent/DE69827127T2/de not_active Revoked
- 1998-05-14 IL IL13266998A patent/IL132669A0/xx unknown
- 1998-05-14 JP JP54887698A patent/JP2001525815A/ja active Pending
- 1998-05-14 BR BR9808772-0A patent/BR9808772A/pt not_active Application Discontinuation
- 1998-05-14 US US09/423,698 patent/US7862823B1/en not_active Expired - Fee Related
- 1998-05-14 PT PT98925715T patent/PT983087E/pt unknown
- 1998-05-14 EP EP98925715A patent/EP0983087B1/fr not_active Revoked
- 1998-05-14 WO PCT/FR1998/000966 patent/WO1998051339A1/fr active Application Filing
- 1998-05-14 PL PL98336704A patent/PL189653B1/pl unknown
- 1998-05-14 KR KR1019997010432A patent/KR100709628B1/ko not_active IP Right Cessation
- 1998-05-14 CZ CZ19994021A patent/CZ295272B6/cs not_active IP Right Cessation
- 1998-05-14 AU AU77730/98A patent/AU748716B2/en not_active Ceased
- 1998-05-14 NZ NZ500738A patent/NZ500738A/en not_active IP Right Cessation
- 1998-05-14 ES ES98925715T patent/ES2227840T3/es not_active Expired - Lifetime
- 1998-05-14 CA CA2289009A patent/CA2289009C/fr not_active Expired - Fee Related
- 1998-05-14 CN CNB988050765A patent/CN1154509C/zh not_active Expired - Fee Related
- 1998-05-14 AT AT98925715T patent/ATE279942T1/de not_active IP Right Cessation
- 1998-05-14 HU HU0002322A patent/HUP0002322A3/hu unknown
-
1999
- 1999-11-01 IL IL132669A patent/IL132669A/en not_active IP Right Cessation
- 1999-11-02 NO NO19995349A patent/NO320415B1/no not_active IP Right Cessation
-
2007
- 2007-05-17 IL IL183296A patent/IL183296A0/en unknown
-
2010
- 2010-11-22 US US12/951,867 patent/US8029798B2/en not_active Expired - Fee Related
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
B25D | Requested change of name of applicant approved |
Owner name: AVENTIS PASTEUR (FR) Free format text: ALTERADO DE: PASTEUR MERIEUX SERUMS ET VACCINS S.A. |
|
B25G | Requested change of headquarter approved |
Owner name: AVENTIS PASTEUR (FR) Free format text: SEDE ALTERADA CONFORME SOLICITADO NA PETICAO NO 020070077844/RJ DE 12/06/2007. |
|
B25D | Requested change of name of applicant approved |
Owner name: SANOFI PASTEUR (FR) Free format text: ALTERADO DE: AVENTIS PASTEUR |
|
B07A | Application suspended after technical examination (opinion) [chapter 7.1 patent gazette] | ||
B09B | Patent application refused [chapter 9.2 patent gazette] |
Free format text: DE ACORDO COM O ARTIGO 37, INDEFIRO O PRESENTE PEDIDO, TENDO POR BASE O ART. 13 COMBINADO COM O ART. 8O DA LPI 9279/96 |
|
B12B | Appeal against refusal [chapter 12.2 patent gazette] |