BRPI0510570A - composição de vacina - Google Patents

composição de vacina

Info

Publication number
BRPI0510570A
BRPI0510570A BRPI0510570-6A BRPI0510570A BRPI0510570A BR PI0510570 A BRPI0510570 A BR PI0510570A BR PI0510570 A BRPI0510570 A BR PI0510570A BR PI0510570 A BRPI0510570 A BR PI0510570A
Authority
BR
Brazil
Prior art keywords
vaccine composition
antigen
vaccine
eso
saponin
Prior art date
Application number
BRPI0510570-6A
Other languages
English (en)
Inventor
Vincent Brichard
Remi M Palmantier
Melinda Meaders
Claudine Elvire Marie Bruck
Original Assignee
Glaxosmithkline Biolog Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glaxosmithkline Biolog Sa filed Critical Glaxosmithkline Biolog Sa
Publication of BRPI0510570A publication Critical patent/BRPI0510570A/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/0005—Vertebrate antigens
    • A61K39/0011—Cancer antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/0005—Vertebrate antigens
    • A61K39/0011—Cancer antigens
    • A61K39/001184—Cancer testis antigens, e.g. SSX, BAGE, GAGE or SAGE
    • A61K39/001186—MAGE
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/0005—Vertebrate antigens
    • A61K39/0011—Cancer antigens
    • A61K39/001184—Cancer testis antigens, e.g. SSX, BAGE, GAGE or SAGE
    • A61K39/001188—NY-ESO
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511—Organic adjuvants
    • A61K2039/55561—CpG containing adjuvants; Oligonucleotide containing adjuvants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511—Organic adjuvants
    • A61K2039/55577—Saponins; Quil A; QS21; ISCOMS

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Mycology (AREA)
  • Oncology (AREA)
  • Epidemiology (AREA)
  • Microbiology (AREA)
  • Immunology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicinal Preparation (AREA)

Abstract

COMPOSIçãO DE VACINA. A presente invenção fornece novas formulações de vacina para o tratamento de antígenos do câncer. A vacina compreende um antígeno MAGE-3 modificado, um antígeno NY-ESO- 1, e um adjuvante compreendendo uma saponina e um oligonucleotídeo imunoestimulador.
BRPI0510570-6A 2004-05-04 2005-05-02 composição de vacina BRPI0510570A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB0409940.4A GB0409940D0 (en) 2004-05-04 2004-05-04 Vaccine
PCT/EP2005/004956 WO2005105139A2 (en) 2004-05-04 2005-05-02 Mage-3 and ny-eso-1 based polyvalent vaccine for cancer immunotherapy

Publications (1)

Publication Number Publication Date
BRPI0510570A true BRPI0510570A (pt) 2007-11-20

Family

ID=32482653

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0510570-6A BRPI0510570A (pt) 2004-05-04 2005-05-02 composição de vacina

Country Status (16)

Country Link
US (1) US20070243196A1 (pt)
EP (1) EP1755657A2 (pt)
JP (1) JP2007536326A (pt)
CN (1) CN1980691A (pt)
AU (1) AU2005237256A1 (pt)
BR (1) BRPI0510570A (pt)
CA (1) CA2564470A1 (pt)
GB (1) GB0409940D0 (pt)
IL (1) IL178681A0 (pt)
MA (1) MA28639B1 (pt)
MX (1) MXPA06012723A (pt)
NO (1) NO20065480L (pt)
NZ (1) NZ550967A (pt)
RU (1) RU2006138283A (pt)
WO (1) WO2005105139A2 (pt)
ZA (1) ZA200608693B (pt)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2007137986A2 (en) * 2006-05-26 2007-12-06 Glaxosmithkline Biologicals Sa Vaccination against cancer
GB0612342D0 (en) * 2006-06-21 2006-08-02 Glaxosmithkline Biolog Sa Method
PL2118128T3 (pl) * 2007-01-15 2013-03-29 Glaxosmithkline Biologicals Sa Białka fuzyjne zawierające antygeny odrzucenia nowotworu NY-ESO-1 i LAGE-1
WO2008110372A1 (en) 2007-03-13 2008-09-18 University Of Zurich Monoclonal human tumor-specific antibody
PT2148697E (pt) 2007-05-24 2012-12-24 Glaxosmithkline Biolog Sa Composição liofilizada de wt-1 contendo cpg
WO2009127666A2 (en) * 2008-04-15 2009-10-22 Glaxosmithkline Biologicals S.A. Method and compositions
CN101381402B (zh) * 2008-10-20 2011-06-01 中国人民解放军第三军医大学 Ny-eso-1肿瘤抗原模拟表位及其应用
EP2408933A2 (en) 2009-03-17 2012-01-25 MDxHealth SA Improved detection of gene expression
GB0910046D0 (en) 2009-06-10 2009-07-22 Glaxosmithkline Biolog Sa Novel compositions
DK2663580T3 (en) * 2011-01-10 2017-03-13 Ct Atlantic Ltd COMBINATION THERAPY INCLUDING TUMOR ASSOCIATED ANTI-BINDING ANTIBODIES
GB201116248D0 (en) 2011-09-20 2011-11-02 Glaxosmithkline Biolog Sa Liposome production using isopropanol
CA3027289A1 (en) * 2013-05-14 2014-11-20 Zoetis Services Llc Vaccine compositions comprising sp oil and p-class immunostimulatory oligonucleotides
AU2014292926B2 (en) 2013-07-25 2020-03-05 Exicure Operating Company Spherical nucleic acid-based constructs as immunostimulatory agents for prophylactic and therapeutic use
JP6581604B2 (ja) 2014-06-04 2019-09-25 イグジキュア, インコーポレーテッドExicure, Inc. 予防的または治療的適用のためのリポソーム球状核酸による免疫調節物質の多価送達
GB201413665D0 (en) 2014-07-03 2014-09-17 Transimmune Ag And Yale University Method for obtaining globally activated monocytes
WO2016019298A2 (en) * 2014-08-01 2016-02-04 Texas Tech University System Cancer testis antigen sperm protein 17 as a target for breast cancer immunotherapy and diagnosis
CA2968531A1 (en) 2014-11-21 2016-05-26 Northwestern University The sequence-specific cellular uptake of spherical nucleic acid nanoparticle conjugates
US11364304B2 (en) 2016-08-25 2022-06-21 Northwestern University Crosslinked micellar spherical nucleic acids
US11696954B2 (en) 2017-04-28 2023-07-11 Exicure Operating Company Synthesis of spherical nucleic acids using lipophilic moieties
WO2018226931A1 (en) * 2017-06-07 2018-12-13 David Weiner Mage-a vaccines and methods of treatment using the same
WO2019061297A1 (zh) * 2017-09-29 2019-04-04 苏州工业园区唯可达生物科技有限公司 一种cd4辅助性t细胞表位融合肽及其疫苗
GB201804468D0 (en) * 2018-03-21 2018-05-02 Valo Therapeutics Oy PeptiCRAd Cancer Therapy

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5057540A (en) * 1987-05-29 1991-10-15 Cambridge Biotech Corporation Saponin adjuvant
US5278302A (en) * 1988-05-26 1994-01-11 University Patents, Inc. Polynucleotide phosphorodithioates
US4912094B1 (en) * 1988-06-29 1994-02-15 Ribi Immunochem Research Inc. Modified lipopolysaccharides and process of preparation
FR2649012B1 (fr) * 1989-07-03 1991-10-25 Seppic Sa Emulsions multiphasiques injectables
FR2649013B1 (fr) * 1989-07-03 1991-10-25 Seppic Sa Vaccins et vecteurs de principes actifs fluides contenant une huile metabolisable
AU725615B2 (en) * 1996-02-23 2000-10-12 British Telecommunications Public Limited Company Optical interconnect
DE69943359D1 (de) * 1998-02-05 2011-05-26 Glaxosmithkline Biolog Sa Tumorassoziierte Antigenderivate der Mage-Familie, zur Herstellung von Fusionsproteinen mit T-Helper Epitope und Zusammensetzungen zur Impfung
US6686147B1 (en) * 1998-07-15 2004-02-03 Ludwig Institute For Cancer Research Cancer associated antigens and uses therefor
US20030044813A1 (en) * 2001-03-30 2003-03-06 Old Lloyd J. Cancer-testis antigens

Also Published As

Publication number Publication date
JP2007536326A (ja) 2007-12-13
NZ550967A (en) 2009-01-31
MXPA06012723A (es) 2007-02-14
IL178681A0 (en) 2007-02-11
AU2005237256A1 (en) 2005-11-10
ZA200608693B (en) 2010-01-27
CN1980691A (zh) 2007-06-13
CA2564470A1 (en) 2005-11-10
NO20065480L (no) 2006-11-28
EP1755657A2 (en) 2007-02-28
RU2006138283A (ru) 2008-06-10
MA28639B1 (fr) 2007-06-01
WO2005105139A2 (en) 2005-11-10
US20070243196A1 (en) 2007-10-18
GB0409940D0 (en) 2004-06-09
WO2005105139A3 (en) 2006-04-13

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Legal Events

Date Code Title Description
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE AS 6A E 7A ANUIDADES.

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 2158 DE 15/05/2012.