US6207646B1
(en)
|
1994-07-15 |
2001-03-27 |
University Of Iowa Research Foundation |
Immunostimulatory nucleic acid molecules
|
US6977245B2
(en)
|
1999-04-12 |
2005-12-20 |
The United States Of America As Represented By The Department Of Health And Human Services |
Oligodeoxynucleotide and its use to induce an immune response
|
US20050226890A1
(en)
*
|
1999-08-12 |
2005-10-13 |
Cohen David I |
Tat-based vaccine compositions and methods of making and using same
|
US20050244434A1
(en)
*
|
1999-08-12 |
2005-11-03 |
Cohen David I |
Tat-based tolerogen compositions and methods of making and using same
|
EP1322655B1
(en)
|
2000-01-14 |
2007-11-14 |
The Government of the United States of America, as represented by the Secretary of the Department of Health and Human Services |
Oligodeoxynucleotide and its use to induce an immune response
|
US7129222B2
(en)
|
2000-03-10 |
2006-10-31 |
Dynavax Technologies Corporation |
Immunomodulatory formulations and methods for use thereof
|
US20030129251A1
(en)
|
2000-03-10 |
2003-07-10 |
Gary Van Nest |
Biodegradable immunomodulatory formulations and methods for use thereof
|
WO2002013857A2
(en)
*
|
2000-08-17 |
2002-02-21 |
Intercell Biomedizinische Forschungs- Und Entwicklungs Ag |
A vaccine which comprises at least one antigen and a cathelididin derived antimicrobial peptide or a derivative thereof
|
US20030049266A1
(en)
|
2000-12-27 |
2003-03-13 |
Fearon Karen L. |
Immunomodulatory polynucleotides and methods of using the same
|
WO2002053184A2
(en)
|
2001-01-05 |
2002-07-11 |
Intercell Ag |
Uses for polycationic compounds as vaccine adjuvants
|
US20040081655A1
(en)
*
|
2001-01-05 |
2004-04-29 |
Karen Lingnau |
Methods and compositions comprising polycationic compounds
|
AU2002345847B2
(en)
|
2001-06-21 |
2008-05-29 |
Dynavax Technologies Corporation |
Chimeric immunomodulatory compounds and methods of using the same
|
US7666674B2
(en)
|
2001-07-27 |
2010-02-23 |
The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services |
Use of sterically stabilized cationic liposomes to efficiently deliver CPG oligonucleotides in vivo
|
AU2002326561B2
(en)
|
2001-08-07 |
2008-04-03 |
Dynavax Technologies Corporation |
Immunomodulatory compositions, formulations, and methods for use thereof
|
US7354909B2
(en)
*
|
2001-08-14 |
2008-04-08 |
The United States Of America As Represented By Secretary Of The Department Of Health And Human Services |
Method for rapid generation of mature dendritic cells
|
DE60234375D1
(de)
|
2001-09-14 |
2009-12-24 |
Cytos Biotechnology Ag |
VERPACKUNG VON IMMUNSTIMULIERENDEM CpG IN VIRUSÄHNLICHEN PARTIKELN: HERSTELLUNGSVERFAHREN UND VERWENDUNG
|
US20030134810A1
(en)
*
|
2001-10-09 |
2003-07-17 |
Chris Springate |
Methods and compositions comprising biocompatible materials useful for the administration of therapeutic agents
|
US20030139364A1
(en)
*
|
2001-10-12 |
2003-07-24 |
University Of Iowa Research Foundation |
Methods and products for enhancing immune responses using imidazoquinoline compounds
|
US8466116B2
(en)
|
2001-12-20 |
2013-06-18 |
The Unites States Of America As Represented By The Secretary Of The Department Of Health And Human Services |
Use of CpG oligodeoxynucleotides to induce epithelial cell growth
|
WO2003054161A2
(en)
|
2001-12-20 |
2003-07-03 |
The Government Of The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services |
USE OF CpG OLIGODEOXYNUCLEOTIDES TO INDUCE ANGIOGENESIS
|
US8088388B2
(en)
|
2002-02-14 |
2012-01-03 |
United Biomedical, Inc. |
Stabilized synthetic immunogen delivery system
|
EP1513552B1
(en)
*
|
2002-06-20 |
2010-12-01 |
Cytos Biotechnology AG |
Packaged virus-like particles in combination with cpg for use as adjuvants with allergens : method of preparation and use
|
US20040053880A1
(en)
|
2002-07-03 |
2004-03-18 |
Coley Pharmaceutical Group, Inc. |
Nucleic acid compositions for stimulating immune responses
|
US7807803B2
(en)
|
2002-07-03 |
2010-10-05 |
Coley Pharmaceutical Group, Inc. |
Nucleic acid compositions for stimulating immune responses
|
US8263091B2
(en)
|
2002-09-18 |
2012-09-11 |
The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services |
Method of treating and preventing infections in immunocompromised subjects with immunostimulatory CpG oligonucleotides
|
JP5116971B2
(ja)
|
2002-10-15 |
2013-01-09 |
インターセル アーゲー |
B群連鎖球菌の接着因子をコードする核酸、b群連鎖球菌の接着因子、およびその使用
|
CA2502015A1
(en)
|
2002-12-11 |
2004-06-24 |
Coley Pharmaceutical Group, Inc. |
5' cpg nucleic acids and methods of use
|
SI1575977T1
(sl)
|
2002-12-23 |
2010-01-29 |
Dynavax Tech Corp |
Imunostimulirni sekvenčni polinukleotidi in postopki za njihovo uporabo
|
US8158768B2
(en)
|
2002-12-23 |
2012-04-17 |
Dynavax Technologies Corporation |
Immunostimulatory sequence oligonucleotides and methods of using the same
|
US8193185B2
(en)
|
2003-01-21 |
2012-06-05 |
Novartis Vaccines And Diagnostics, Inc. |
Use of tryptanthrin compounds for immune potentiation
|
EP2287315A1
(en)
|
2003-03-04 |
2011-02-23 |
Intercell AG |
Streptococcus pyogenes antigens
|
WO2004084938A1
(en)
*
|
2003-03-24 |
2004-10-07 |
Intercell Ag |
Improved vaccines
|
EP2258365B1
(en)
|
2003-03-28 |
2013-05-29 |
Novartis Vaccines and Diagnostics, Inc. |
Use of organic compounds for immunopotentiation
|
US7628994B2
(en)
|
2003-03-31 |
2009-12-08 |
Intercell Ag |
S. epidermidis antigens
|
EP2311991A1
(en)
|
2003-04-15 |
2011-04-20 |
Intercell AG |
S. pneumoniae antigens
|
EP2287177A3
(en)
|
2003-05-07 |
2011-08-31 |
Intercell AG |
Streptococcus agalactiae antigens I + II
|
US20080175856A1
(en)
|
2003-05-30 |
2008-07-24 |
Intercell Ag |
Enterococcus Antigens
|
CN1822856B
(zh)
*
|
2003-07-11 |
2010-04-28 |
英特塞尔股份公司 |
Hcv疫苗
|
US7927580B2
(en)
*
|
2004-03-16 |
2011-04-19 |
Nanirx, Inc. |
Tat-based immunomodulatory compositions and methods of their discovery and use
|
CA2571710A1
(en)
|
2004-06-24 |
2006-11-02 |
Nicholas Valiante |
Small molecule immunopotentiators and assays for their detection
|
WO2006002422A2
(en)
|
2004-06-24 |
2006-01-05 |
Novartis Vaccines And Diagnostics Inc. |
Compounds for immunopotentiation
|
WO2007011776A2
(en)
*
|
2005-07-15 |
2007-01-25 |
Novartis Ag |
Pamps, pathogen associated molecular patterns
|
EP1973608A1
(en)
|
2005-12-14 |
2008-10-01 |
Cytos Biotechnology AG |
Immunostimulatory nucleic acid packaged particles for the treatment of hypersensitivity
|
WO2007144150A1
(en)
|
2006-06-12 |
2007-12-21 |
Cytos Biotechnology Ag |
Processes for packaging oligonucleotides into virus-like particles of rna bacteriophages
|
EP2292644A3
(en)
|
2006-07-07 |
2011-05-25 |
Intercell AG |
Small Streptococcus pyogenes antigens and their use
|
US8129165B2
(en)
|
2006-09-15 |
2012-03-06 |
Intercell Ag |
Borrelia antigens
|
EP1923069A1
(en)
|
2006-11-20 |
2008-05-21 |
Intercell AG |
Peptides protective against S. pneumoniae and compositions, methods and uses relating thereto
|
CA2671873C
(en)
|
2006-12-12 |
2018-10-09 |
Brian Stephen Sproat |
Oligonucleotides containing high concentrations of guanine monomers
|
EP2120984A2
(en)
|
2007-01-12 |
2009-11-25 |
Intercell AG |
Protective proteins of s. agalactiae, combinations thereof and methods of using the same
|
EP2121048B9
(en)
|
2007-02-19 |
2016-02-24 |
Marine Polymer Technologies, Inc. |
Hemostatic compositions and therapeutic regimens
|
EP2152731A2
(en)
|
2007-05-02 |
2010-02-17 |
Intercell AG |
Klebsiella antigens
|
EP2012122A1
(en)
|
2007-07-06 |
2009-01-07 |
Medigene AG |
Mutated parvovirus structural proteins as vaccines
|
US20100203083A1
(en)
|
2007-05-31 |
2010-08-12 |
Medigene Ag |
Mutated structural protein of a parvovirus
|
CA2690271A1
(en)
|
2007-06-18 |
2008-12-24 |
Intercell Ag |
Chlamydia antigens
|
WO2009030254A1
(en)
|
2007-09-04 |
2009-03-12 |
Curevac Gmbh |
Complexes of rna and cationic peptides for transfection and for immunostimulation
|
DE102007044093A1
(de)
*
|
2007-09-14 |
2009-03-19 |
Phenion Gmbh & Co. Kg |
Nukleinsäurehaltige kosmetische und/oder pharmazeutische Zubereitungen zur Induktion antimikrobieller Peptide in epithelialen Deckgeweben
|
CN101977927A
(zh)
|
2008-03-17 |
2011-02-16 |
英特塞尔股份公司 |
针对肺炎链球菌保护的肽以及与其有关的组合物、方法和用途
|
JP5659332B2
(ja)
|
2008-06-27 |
2015-01-28 |
ゾエティス・エルエルシー |
新規なアジュバント組成物
|
US20100233270A1
(en)
|
2009-01-08 |
2010-09-16 |
Northwestern University |
Delivery of Oligonucleotide-Functionalized Nanoparticles
|
EP2424882A2
(en)
|
2009-02-05 |
2012-03-07 |
Intercell AG |
Peptides protective against e. faecalis, methods and uses relating thereto
|
WO2010092176A2
(en)
|
2009-02-13 |
2010-08-19 |
Intercell Ag |
Nontypable haemophilus influenzae antigens
|
BRPI1009215B1
(pt)
|
2009-03-23 |
2019-10-29 |
Nanirx Inc |
composição farmacêutica compreendendo uma sequência de aminoácidos modificada da proteína trans-ativadora de transcrição (tat) do vírus da imunodeficiência humana (hiv) e uso de um polipeptídeo derivado de tat para tratar câncer
|
US20110053829A1
(en)
|
2009-09-03 |
2011-03-03 |
Curevac Gmbh |
Disulfide-linked polyethyleneglycol/peptide conjugates for the transfection of nucleic acids
|
EP2319871A1
(en)
|
2009-11-05 |
2011-05-11 |
Sanofi-aventis |
Polypeptides for binding to the "receptor for advanced glycation endproducts" as well as compositions and methods involving the same
|
WO2011042548A1
(en)
|
2009-10-09 |
2011-04-14 |
Sanofi-Aventis |
Polypeptides for binding to the "receptor for advanced glycation endproducts" as well as compositions and methods involving the same
|
EP2308896A1
(en)
|
2009-10-09 |
2011-04-13 |
Sanofi-aventis |
Polypeptides for binding to the "receptor for advanced glycation endproducts" as well as compositions and methods involving the same
|
EA201500857A1
(ru)
|
2010-05-26 |
2016-06-30 |
Селекта Байосайенсиз, Инк. |
Комбинированные вакцины с синтетическими наноносителями
|
RS55707B2
(sr)
|
2010-09-03 |
2022-10-31 |
Valneva Austria Gmbh |
Izolovani polipeptid toksin a i toksin b proteina c. difficile i njihova upotreba
|
WO2012031760A1
(en)
|
2010-09-08 |
2012-03-15 |
Medigene Ag |
Parvovirus mutated structural proteins comprising cross - protective b - cell epitopes of a hpv l2 protein as well as products and methods relating thereto
|
US9441013B2
(en)
*
|
2011-05-17 |
2016-09-13 |
H. Lee Moffitt Cancer Center And Research Institute, Inc. |
Melanocortin 1 receptor ligands and methods of use
|
EA201490381A1
(ru)
*
|
2011-07-29 |
2014-06-30 |
Селекта Байосайенсиз, Инк. |
Синтетические наноносители, которые стимулируют формирование гуморального иммунного ответа и иммунного ответа, опосредованного цитотоксическими т-лимфоцитами (ctl)
|
EP2809354B1
(en)
*
|
2012-01-31 |
2021-04-14 |
CureVac AG |
Negatively charged nucleic acid comprising complexes for immunostimulation
|
WO2013113325A1
(en)
*
|
2012-01-31 |
2013-08-08 |
Curevac Gmbh |
Negatively charged nucleic acid comprising complexes for immunostimulation
|
WO2013113326A1
(en)
*
|
2012-01-31 |
2013-08-08 |
Curevac Gmbh |
Pharmaceutical composition comprising a polymeric carrier cargo complex and at least one protein or peptide antigen
|
CA2919268C
(en)
|
2013-07-25 |
2023-09-05 |
Exicure, Inc. |
Spherical nucleic acid-based constructs as immunostimulatory agents for prophylactic and therapeutic use
|
SG10201801431TA
(en)
|
2013-08-21 |
2018-04-27 |
Curevac Ag |
Respiratory syncytial virus (rsv) vaccine
|
CA2924526A1
(en)
|
2013-09-19 |
2015-03-26 |
Paul Joseph Dominowski |
Water-in-oil emulsions comprising immunostimulatory oligonucleotides
|
JP2016533352A
(ja)
|
2013-10-04 |
2016-10-27 |
ピーアイエヌ ファーマ インコーポレイテッド |
免疫刺激性HIV Tat誘導体ポリペプチドによる癌の治療
|
EP3129050A2
(en)
|
2014-04-01 |
2017-02-15 |
CureVac AG |
Polymeric carrier cargo complex for use as an immunostimulating agent or as an adjuvant
|
KR102290205B1
(ko)
|
2014-06-04 |
2021-08-20 |
엑시큐어, 인크. |
예방 또는 치료 용도를 위한 리포솜성 구형 핵산에 의한 면역 조절인자의 다가 전달
|
CA2968531A1
(en)
|
2014-11-21 |
2016-05-26 |
Northwestern University |
The sequence-specific cellular uptake of spherical nucleic acid nanoparticle conjugates
|
AR103427A1
(es)
|
2015-01-16 |
2017-05-10 |
Zoetis Services Llc |
Vacuna contra la fiebre aftosa
|
US11364304B2
(en)
|
2016-08-25 |
2022-06-21 |
Northwestern University |
Crosslinked micellar spherical nucleic acids
|
WO2018201090A1
(en)
|
2017-04-28 |
2018-11-01 |
Exicure, Inc. |
Synthesis of spherical nucleic acids using lipophilic moieties
|
WO2019158636A1
(en)
|
2018-02-16 |
2019-08-22 |
2A Pharma Ab |
Parvovirus structural protein for the treatment of autoimmune diseases
|
EP3527223A1
(en)
|
2018-02-16 |
2019-08-21 |
2A Pharma AB |
Mutated parvovirus structural protein
|
MX2021013111A
(es)
|
2019-05-20 |
2021-11-17 |
Valneva Se |
Una vacuna de subunidad para el tratamiento o la prevencion de una infeccion del tracto respiratorio.
|
WO2023083964A1
(en)
|
2021-11-11 |
2023-05-19 |
2A Pharma Ab |
Parvovirus structural protein against beta- and gamma-hpv
|