ATE392904T1 - Pharmazeutische zusammensetzung zur immunstimulation und zur zubereitung von impfstoffen enthaltend ein antigen, und als adjuvantien ein immunogenes oligodesoxynukleotid und ein polykationisches polypeptid - Google Patents
Pharmazeutische zusammensetzung zur immunstimulation und zur zubereitung von impfstoffen enthaltend ein antigen, und als adjuvantien ein immunogenes oligodesoxynukleotid und ein polykationisches polypeptidInfo
- Publication number
- ATE392904T1 ATE392904T1 AT01903625T AT01903625T ATE392904T1 AT E392904 T1 ATE392904 T1 AT E392904T1 AT 01903625 T AT01903625 T AT 01903625T AT 01903625 T AT01903625 T AT 01903625T AT E392904 T1 ATE392904 T1 AT E392904T1
- Authority
- AT
- Austria
- Prior art keywords
- oligodesoxynucleotide
- immuno
- immunogenic
- adjuvants
- stimulation
- Prior art date
Links
- 239000002671 adjuvant Substances 0.000 title 1
- 239000000427 antigen Substances 0.000 title 1
- 102000036639 antigens Human genes 0.000 title 1
- 108091007433 antigens Proteins 0.000 title 1
- 230000002163 immunogen Effects 0.000 title 1
- 230000003308 immunostimulating effect Effects 0.000 title 1
- 239000008194 pharmaceutical composition Substances 0.000 title 1
- 229920001184 polypeptide Polymers 0.000 title 1
- 102000004196 processed proteins & peptides Human genes 0.000 title 1
- 108090000765 processed proteins & peptides Proteins 0.000 title 1
- 229960005486 vaccine Drugs 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/39—Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55561—CpG containing adjuvants; Oligonucleotide containing adjuvants
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Immunology (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- General Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Microbiology (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Mycology (AREA)
- Epidemiology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Transplantation (AREA)
- Virology (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicinal Preparation (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| AT0012900A AT409085B (de) | 2000-01-28 | 2000-01-28 | Pharmazeutische zusammensetzung zur immunmodulation und herstellung von vakzinen |
| PCT/EP2001/000087 WO2001054720A1 (en) | 2000-01-28 | 2001-01-05 | Pharmaceutical composition for immunomodulation and preparation of vaccines comprising an antigen and an immunogenic oligodeoxynucleotide and a polycationic polymer as adjuvants |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE392904T1 true ATE392904T1 (de) | 2008-05-15 |
Family
ID=3635970
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT0012900A AT409085B (de) | 2000-01-28 | 2000-01-28 | Pharmazeutische zusammensetzung zur immunmodulation und herstellung von vakzinen |
| AT01903625T ATE392904T1 (de) | 2000-01-28 | 2001-01-05 | Pharmazeutische zusammensetzung zur immunstimulation und zur zubereitung von impfstoffen enthaltend ein antigen, und als adjuvantien ein immunogenes oligodesoxynukleotid und ein polykationisches polypeptid |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT0012900A AT409085B (de) | 2000-01-28 | 2000-01-28 | Pharmazeutische zusammensetzung zur immunmodulation und herstellung von vakzinen |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US20020197269A1 (de) |
| EP (1) | EP1251871B1 (de) |
| JP (1) | JP2003520824A (de) |
| AR (1) | AR026940A1 (de) |
| AT (2) | AT409085B (de) |
| AU (1) | AU784403B2 (de) |
| CA (1) | CA2396884A1 (de) |
| DE (1) | DE60133717T2 (de) |
| ES (1) | ES2304376T3 (de) |
| PE (1) | PE20011217A1 (de) |
| UY (1) | UY26555A1 (de) |
| WO (1) | WO2001054720A1 (de) |
Families Citing this family (89)
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| US6207646B1 (en) | 1994-07-15 | 2001-03-27 | University Of Iowa Research Foundation | Immunostimulatory nucleic acid molecules |
| US6977245B2 (en) | 1999-04-12 | 2005-12-20 | The United States Of America As Represented By The Department Of Health And Human Services | Oligodeoxynucleotide and its use to induce an immune response |
| US20050244434A1 (en) * | 1999-08-12 | 2005-11-03 | Cohen David I | Tat-based tolerogen compositions and methods of making and using same |
| US20050226890A1 (en) * | 1999-08-12 | 2005-10-13 | Cohen David I | Tat-based vaccine compositions and methods of making and using same |
| DE60131430T2 (de) | 2000-01-14 | 2008-10-16 | The Government Of The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services | Oligodeoxynukleotide und ihre verwendung zur induktion einer immunreaktion |
| US20030129251A1 (en) | 2000-03-10 | 2003-07-10 | Gary Van Nest | Biodegradable immunomodulatory formulations and methods for use thereof |
| US7129222B2 (en) | 2000-03-10 | 2006-10-31 | Dynavax Technologies Corporation | Immunomodulatory formulations and methods for use thereof |
| WO2002013857A2 (en) * | 2000-08-17 | 2002-02-21 | Intercell Biomedizinische Forschungs- Und Entwicklungs Ag | A vaccine which comprises at least one antigen and a cathelididin derived antimicrobial peptide or a derivative thereof |
| AU2002231336B2 (en) | 2000-12-27 | 2007-06-28 | Surefire Medical, Inc. D/B/A Trisalus Life Sciences | Immunomodulatory polynucleotides and methods of using the same |
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| AU2002361468A1 (en) * | 2001-08-14 | 2003-03-18 | The Government Of The United States Of America As Represented By The Secretary Of Health And Human S | Method for rapid generation of mature dendritic cells |
| DE60234375D1 (de) * | 2001-09-14 | 2009-12-24 | Cytos Biotechnology Ag | VERPACKUNG VON IMMUNSTIMULIERENDEM CpG IN VIRUSÄHNLICHEN PARTIKELN: HERSTELLUNGSVERFAHREN UND VERWENDUNG |
| US20030134810A1 (en) * | 2001-10-09 | 2003-07-17 | Chris Springate | Methods and compositions comprising biocompatible materials useful for the administration of therapeutic agents |
| US20030139364A1 (en) * | 2001-10-12 | 2003-07-24 | University Of Iowa Research Foundation | Methods and products for enhancing immune responses using imidazoquinoline compounds |
| US8466116B2 (en) | 2001-12-20 | 2013-06-18 | The Unites States Of America As Represented By The Secretary Of The Department Of Health And Human Services | Use of CpG oligodeoxynucleotides to induce epithelial cell growth |
| AU2002366710A1 (en) | 2001-12-20 | 2003-07-09 | The Government Of The United States Of America As Represented By The Secretary Of The Department Of | USE OF CpG OLIGODEOXYNUCLEOTIDES TO INDUCE ANGIOGENESIS |
| US8088388B2 (en) | 2002-02-14 | 2012-01-03 | United Biomedical, Inc. | Stabilized synthetic immunogen delivery system |
| PL375306A1 (en) * | 2002-06-20 | 2005-11-28 | Cytos Biotechnology Ag | Packaged virus-like particles for use as adjuvants: method of preparation and use |
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| US8263091B2 (en) | 2002-09-18 | 2012-09-11 | The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services | Method of treating and preventing infections in immunocompromised subjects with immunostimulatory CpG oligonucleotides |
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| AU2015269412B2 (en) | 2014-06-04 | 2020-03-12 | Exicure Operating Company | Multivalent delivery of immune modulators by liposomal spherical nucleic acids for prophylactic or therapeutic applications |
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| FI3244920T3 (fi) | 2015-01-16 | 2023-08-04 | Zoetis Services Llc | Suu- ja sorkkatautirokote |
| WO2018039629A2 (en) | 2016-08-25 | 2018-03-01 | Northwestern University | Micellar spherical nucleic acids from thermoresponsive, traceless templates |
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| WO2019158636A1 (en) | 2018-02-16 | 2019-08-22 | 2A Pharma Ab | Parvovirus structural protein for the treatment of autoimmune diseases |
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| CN114127101A (zh) | 2019-05-20 | 2022-03-01 | 瓦尔尼瓦公司 | 用于治疗或预防呼吸道感染的亚单位疫苗 |
| WO2023083964A1 (en) | 2021-11-11 | 2023-05-19 | 2A Pharma Ab | Parvovirus structural protein against beta- and gamma-hpv |
| CN117860879A (zh) * | 2024-01-10 | 2024-04-12 | 广州医科大学附属肿瘤医院 | 一种纳米疫苗递送系统及其制备方法和应用 |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NZ221306A (en) * | 1986-08-15 | 1990-02-26 | Commw Scient Ind Res Org | 2-component immunoadjuvant comprising a mycobacterial free immunoadjuvant oil and a polycationic polyelectrolyte immunoadjuvant and vaccines thereof |
| DE69535905D1 (de) * | 1994-07-15 | 2009-02-26 | Coley Pharm Group Inc | Immunomodulatorische Oligonukleotide |
| CO4600681A1 (es) * | 1996-02-24 | 1998-05-08 | Boehringer Ingelheim Pharma | Composicion farmaceutica para la modulacion inmunitaria |
| EP0930893B1 (de) * | 1996-10-11 | 2005-04-13 | The Regents of The University of California | Immunostimulierende oligonucleotidekonjugate |
| AU7589398A (en) * | 1997-05-19 | 1998-12-11 | Merck & Co., Inc. | Oligonucleotide adjuvant |
| US6589940B1 (en) * | 1997-06-06 | 2003-07-08 | Dynavax Technologies Corporation | Immunostimulatory oligonucleotides, compositions thereof and methods of use thereof |
| DE19803453A1 (de) * | 1998-01-30 | 1999-08-12 | Boehringer Ingelheim Int | Vakzine |
-
2000
- 2000-01-28 AT AT0012900A patent/AT409085B/de not_active IP Right Cessation
- 2000-12-13 AR ARP000106610A patent/AR026940A1/es unknown
-
2001
- 2001-01-05 WO PCT/EP2001/000087 patent/WO2001054720A1/en not_active Ceased
- 2001-01-05 AU AU31665/01A patent/AU784403B2/en not_active Ceased
- 2001-01-05 JP JP2001554703A patent/JP2003520824A/ja not_active Withdrawn
- 2001-01-05 CA CA002396884A patent/CA2396884A1/en not_active Abandoned
- 2001-01-05 AT AT01903625T patent/ATE392904T1/de not_active IP Right Cessation
- 2001-01-05 EP EP01903625A patent/EP1251871B1/de not_active Expired - Lifetime
- 2001-01-05 DE DE60133717T patent/DE60133717T2/de not_active Expired - Lifetime
- 2001-01-05 ES ES01903625T patent/ES2304376T3/es not_active Expired - Lifetime
- 2001-01-24 UY UY26555A patent/UY26555A1/es unknown
- 2001-01-26 PE PE2001000093A patent/PE20011217A1/es not_active Application Discontinuation
-
2002
- 2002-07-25 US US10/205,150 patent/US20020197269A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| AT409085B (de) | 2002-05-27 |
| DE60133717T2 (de) | 2009-07-02 |
| AU3166501A (en) | 2001-08-07 |
| ATA1292000A (de) | 2001-10-15 |
| UY26555A1 (es) | 2001-08-27 |
| ES2304376T3 (es) | 2008-10-16 |
| US20020197269A1 (en) | 2002-12-26 |
| JP2003520824A (ja) | 2003-07-08 |
| PE20011217A1 (es) | 2001-12-04 |
| DE60133717D1 (de) | 2008-06-05 |
| EP1251871B1 (de) | 2008-04-23 |
| WO2001054720A1 (en) | 2001-08-02 |
| AR026940A1 (es) | 2003-03-05 |
| EP1251871A1 (de) | 2002-10-30 |
| AU784403B2 (en) | 2006-03-30 |
| CA2396884A1 (en) | 2001-08-02 |
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